Standout Papers
Citation Impact
Citing Papers
Structural Basis of Transcription: Backtracked RNA Polymerase II at 3.4 Angstrom Resolution
2009 StandoutScienceNobel
Single molecules of the bacterial actin MreB undergo directed treadmilling motion in Caulobacter crescentus
2006 StandoutNobel
De Novo Formation of a Subnuclear Body
2008 Science
Protein stability promotes evolvability
2006 StandoutNobel
Masking mRNA from translation in somatic cells.
1993
Biomolecular condensates: organizers of cellular biochemistry
2017 Standout
Shuttling proteins go both ways
1991
A telomerase component is defective in the human disease dyskeratosis congenita
1999 Nature
The box C/D and H/ACA snoRNPs: key players in the modification, processing and the dynamic folding of ribosomal RNA
2011
Fibrillarin binds directly and specifically to U16 box C/D snoRNA
2000
Identification of a novel nuclear pore-associated protein as a functional target of the HIV-1 Rev protein in yeast
1995 StandoutNobel
X-linked dyskeratosis congenita is caused by mutations in a highly conserved gene with putative nucleolar functions
1998
hnRNP proteins:Localization and transport between the nucleus and the cytoplasm
1993
In vivo dynamics of RNA polymerase II transcription
2007
Identification of a signal for rapid export of proteins from the nucleus
1995 StandoutNobel
A Polymeric Protein Anchors the Chromosomal Origin/ParB Complex at a Bacterial Cell Pole
2008 StandoutNobel
Telomerase Mutations in Families with Idiopathic Pulmonary Fibrosis
2007 StandoutNobel
The multifunctional nucleolus
2007
High-Resolution Mapping Reveals a Conserved, Widespread, Dynamic mRNA Methylation Program in Yeast Meiosis
2013 StandoutNobel
A Common Core RNP Structure Shared between the Small Nucleoar Box C/D RNPs and the Spliceosomal U4 snRNP
2000 StandoutNobel
The Cold Shock Domain Protein LIN-28 Controls Developmental Timing in C. elegans and Is Regulated by the lin-4 RNA
1997 StandoutNobel
A Distinct Nuclear Import Pathway Used by Ribosomal Proteins
1997 StandoutNobel
The two steps of nuclear import, targeting to the nuclear envelope and translocation through the nuclear pore, require different cytosolic factors
1992 StandoutNobel
Nuclear import-export: In search of signals and mechanisms
1991
Dynamic RNA Modifications in Gene Expression Regulation
2017 Standout
Short Telomeres, even in the Presence of Telomerase, Limit Tissue Renewal Capacity
2005 StandoutNobel
The Nuclear Envelope of the Yeast Saccharomyces cerevisiae
1992
Nuclear protein accumulation by facilitated transport and intranuclear binding
1993
A nuclear pore complex protein that contains zinc finger motifs, binds DNA, and faces the nucleoplasm
1993 StandoutNobel
Secondary Structure of Vertebrate Telomerase RNA
2000 StandoutNobel
Spliceosomal snRNA modifications and their function
2010
Structural and functional properties of the evolutionarily ancient Y‐box family of nucleic acid binding proteins
1994
Cytosolic proteins that specifically bind nuclear location signals are receptors for nuclear import
1991
The peptide repeat domain of nucleoporin Nup98 functions as a docking site in transport across the nuclear pore complex
1995 StandoutNobel
The biogenesis and regulation of telomerase holoenzymes
2006
X-Linked Dyskeratosis Congenita Is Predominantly Caused by Missense Mutations in the DKC1 Gene
1999
Human Nop5/Nop58 is a component common to the box C/D small nucleolar ribonucleoproteins
1999
Protein import into nuclei: association and dissociation reactions involving transport substrate, transport factors, and nucleoporins
1995 StandoutNobel
Internuclear migration of chicken progesterone receptor, but not simian virus-40 large tumor antigen, in transient heterokaryons.
1992
Probing the Heme Iron Coordination Structure of Pressure-Induced Cytochrome P420cam
1996
Dyskeratosis congenita in all its forms
2000
Coilin-dependent snRNP assembly is essential for zebrafish embryogenesis
2010
Non-coding RNAs: lessons from the small nuclear and small nucleolar RNAs
2007
Compositional Control of Phase-Separated Cellular Bodies
2016
Nucleolar localization signals of Box H/ACA small nucleolar RNAs
1999
Crystallographic Analysis of the Recognition of a Nuclear Localization Signal by the Nuclear Import Factor Karyopherin α
1998 StandoutNobel
Dyskeratosis congenita: its link to telomerase and aplastic anaemia
2003
Birth of the snoRNPs: the evolution of the modification-guide snoRNAs
1998
Nuclear shuttling: The default pathway for nuclear proteins?
1993
Nuclear export of proteins: The role of nuclear retention
1993
In Vivo Analysis of Cajal Body Movement, Separation, and Joining in Live Human Cells
2000
Role of the Nuclear Transport Factor p10 in Nuclear Import
1996 StandoutScienceNobel
A complex of nuclear pore proteins required for pore function.
1991
Proteins Connecting the Nuclear Pore Complex with the Nuclear Interior
1999 StandoutNobel
Previously identified protein of uncertain function is karyopherin alpha and together with karyopherin beta docks import substrate at nuclear pore complexes.
1995 StandoutNobel
NUCLEOCYTOPLASMIC TRANSPORT: The Soluble Phase
1998
Structure and Function of the Nuclear Pore Complex
1992
Kap104p: A Karyopherin Involved in the Nuclear Transport of Messenger RNA Binding Proteins
1996 StandoutScienceNobel
RNA–protein analysis using a conditional CRISPR nuclease
2013 StandoutNobel
Cbf5p, a potential pseudouridine synthase, and Nhp2p, a putative RNA-binding protein, are present together with Gar1p in all H BOX/ACA-motif snoRNPs and constitute a common bipartite structure
1998
Telomerase core components protect Candida telomeres from aberrant overhang accumulation
2007 StandoutNobel
Genetically encoded reporters of protein kinase A activity reveal impact of substrate tethering
2001 StandoutNobel
RanGTP-mediated nuclear export of karyopherin α involves its interaction with the nucleoporin Nup153
1997 StandoutNobel
Two distinct classes of Ran-binding sites on the nucleoporin Nup-358
1999 StandoutNobel
High-affinity binding of Escherichia coli SecB to the signal sequence region of a presecretory protein.
1995 StandoutNobel
Dynamics of component exchange at PML nuclear bodies
2008
Karyopherin β2 mediates nuclear import of a mRNA binding protein
1997 StandoutNobel
Inhibition of nuclear protein import by nonhydrolyzable analogues of GTP and identification of the small GTPase Ran/TC4 as an essential transport factor [published erratum appears in J Cell Biol 1994 Jan;124(1-2):217]
1993
Antibodies against 70-kD heat shock cognate protein inhibit mediated nuclear import of karyophilic proteins.
1992
A Box H/ACA Small Nucleolar RNA-Like Domain at the Human Telomerase RNA 3′ End
1999
A mutant nuclear protein with similarity to RNA binding proteins interferes with nuclear import in yeast.
1992
Nuclear protein import: Ran-GTP dissociates the karyopherin alphabeta heterodimer by displacing alpha from an overlapping binding site on beta.
1996 StandoutNobel
Nucleolar KKE/D Repeat Proteins Nop56P and Nop58P Interact with Nop1p and Are Required for Ribosome Biogenesis
1997
mRNA binding protein mrnp 41 localizes to both nucleus and cytoplasm
1997 StandoutNobel
A new subclass of nucleoporins that functionally interact with nuclear pore protein NSP1.
1992
Heterozygous telomerase RNA mutations found in dyskeratosis congenita and aplastic anemia reduce telomerase activity via haploinsufficiency
2004
Role of the Box C/D Motif in Localization of Small Nucleolar RNAs to Coiled Bodies and Nucleoli
1999
Structure and biogenesis of small nucleolar RNAs acting as guides for ribosomal RNA modification.
1999
Reconstitution of nuclear protein transport with semi-intact yeast cells.
1993
Nuclear localization signals also mediate the outward movement of proteins from the nucleus.
1994
Concentrating pre-mRNA processing factors in the histone locus body facilitates efficient histone mRNA biogenesis
2016
Identification of Protein p270/Tpr as a Constitutive Component of the Nuclear Pore Complex–attached Intranuclear Filaments
1997
Tuning the ribosome: The influence of rRNA modification on eukaryotic ribosome biogenesis and function
2016
Purification of a Ran-interacting protein that is required for protein import into the nucleus.
1994 StandoutNobel
The GTP-binding protein Ran/TC4 is required for protein import into the nucleus
1993 StandoutNatureNobel
Critical role of reverse transcriptase in the inhibitory mechanism of CNI-H0294 on HIV-1 nuclear translocation.
1996 StandoutNobel
RNA transcription modulates phase transition-driven nuclear body assembly
2015
Functional analysis of the pseudoknot structure in human telomerase RNA
2005 StandoutNobel
Protein export from the nucleus requires the GTPase Ran and GTP hydrolysis.
1995 StandoutNobel
In vivo kinetics of U4/U6·U5 tri-snRNP formation in Cajal bodies
2010
Autoproteolysis in nucleoporin biogenesis
1999 StandoutNobel
A low threshold level of expression of mutant-template telomerase RNA inhibits human tumor cell proliferation
2001 StandoutNobel
The HIV-1 Rev trans-activator shuttles between the nucleus and the cytoplasm.
1994
Haploinsufficiency of t e lomerase reverse transcriptase leads to anticipation in autosomal dominant dyskeratosis congenita
2005 StandoutNobel
The binding site of karyopherin alpha for karyopherin beta overlaps with a nuclear localization sequence.
1996 StandoutNobel
Thermostable inhibitor of cAMP-dependent protein kinase enhances the rate of export of the kinase catalytic subunit from the nucleus.
1994 StandoutNobel
Template Boundary in a Yeast Telomerase Specified by RNA Structure
2000 StandoutScienceNobel
Two yeast nuclear pore complex proteins involved in mRNA export form a cytoplasmically oriented subcomplex
1998 StandoutNobel
Cloning and characterization of human karyopherin β3
1997 StandoutNobel
Small Cajal Body–specific RNAs ofDrosophilaFunction in the Absence of Cajal Bodies
2009
Dyskeratosis congenita: telomerase, telomeres and anticipation
2005
Mammalian karyopherin alpha 1 beta and alpha 2 beta heterodimers: alpha 1 or alpha 2 subunit binds nuclear localization signal and beta subunit interacts with peptide repeat-containing nucleoporins.
1995 StandoutNobel
Movement of the free catalytic subunit of cAMP-dependent protein kinase into and out of the nucleus can be explained by diffusion.
1993 StandoutNobel
The NSR1 gene encodes a protein that specifically binds nuclear localization sequences and has two RNA recognition motifs.
1991
Presence of Multiple Sites Containing Polar Material in SphericalEscherichia coliCells That Lack MreB
2005
Identification of fission yeast nuclear markers using random polypeptide fusions with green fluorescent protein
1996 StandoutNobel
Works of U. Thomas Meier being referenced
SHQ1 is required prior to NAF1 for assembly of H/ACA small nucleolar and telomerase RNPs
2009
Architecture and assembly of mammalian H/ACA small nucleolar and telomerase ribonucleoproteins
2004
A class of nonribosomal nucleolar components is located in chromosome periphery and in nucleolus-derived foci during anaphase and telophase
1997
RNA-guided isomerization of uridine to pseudouridine—pseudouridylation
2014
Nopp 140 shuttles on tracks between nucleolus and cytoplasm
1992 StandoutNobel
The many facets of H/ACA ribonucleoproteins
2005
Characterization of the Nucleolar Gene Product, Treacle, in Treacher Collins Syndrome
2000
Dissecting dyskeratosis
2003
Genetic location of genes encoding enterobacterial common antigen
1985
Nopp140 Functions as a Molecular Link Between the Nucleolus and the Coiled Bodies
1998
A nuclear localization signal binding protein in the nucleolus.
1990 StandoutNobel
A nuclear localization signal binding protein in the nucleolus
1990 StandoutNobel
In vivo kinetics of Cajal body components
2004
NAP57, a mammalian nucleolar protein with a putative homolog in yeast and bacteria.
1994
RNA modification in Cajal bodies
2016
Immunopurified Small Nucleolar Ribonucleoprotein Particles Pseudouridylate rRNA Independently of Their Association with Phosphorylated Nopp140
2002
Stepwise RNP assembly at the site of H/ACA RNA transcription in human cells
2006
Electron paramagnetic resonance properties of liver fluke (Dicrocoelium dendriticum) nitrosyl hemoglobin
1984