Citation Impact
Citing Papers
Complement and microglia mediate early synapse loss in Alzheimer mouse models
2016 StandoutScience
Synaptic Pruning by Microglia Is Necessary for Normal Brain Development
2011 StandoutScience
Sequential Enrichment and Immunocytochemical Visualization of Human Interferon-α-Producing Cells
1990
Polarity and developmental regulation of two PDZ proteins in the retinal pigment epithelium.
2001
Leukocyte Migration and Adhesion
1995
Generation of an Inhibitory Circuit Involving CD8+ T Cells, IL-2, and NK Cell-Derived TGF-β: Contrasting Effects of Anti-CD2 and Anti-CD3
1998
Activation of ERM proteins in vivo by Rho involves phosphatidyl-inositol 4-phosphate 5-kinase and not ROCK kinases
1999
Treml4, an Ig Superfamily Member, Mediates Presentation of Several Antigens to T Cells In Vivo, Including Protective Immunity to HER2 Protein
2011 StandoutNobel
Structural conversion between open and closed forms of radixin: low-angle shadowing electron microscopy 1 1Edited by M. Moody
2001
Normal Development of Mice and Unimpaired Cell Adhesion/Cell Motility/Actin-based Cytoskeleton without Compensatory Up-regulation of Ezrin or Radixin in Moesin Gene Knockout
1999
ERM proteins in cell adhesion and membrane dynamics
1999
Cell mechanics and the cytoskeleton
2010 StandoutNature
The Membrane-Microfilament Linker Ezrin Is Involved in the Formation of the Immunological Synapse and in T Cell Activation
2001
Impaired immune and acute-phase responses in interleukin-6-deficient mice
1994 StandoutNatureNobel
Inflammation and cancer
2002 StandoutNature
Developmental Neuronal Death in Hippocampus Requires the Microglial CD11b Integrin and DAP12 Immunoreceptor
2008
Physical Principles of Membrane Shape Regulation by the Glycocalyx
2019 StandoutNobel
Mice heterozygous for a mutation at the Nf2 tumor suppressor locus develop a range of highly metastatic tumors
1998
Receptor-specific induction of insulin-like growth factor I in human monocytes by advanced glycosylation end product-modified proteins.
1992
Disease-Associated Microglia: A Universal Immune Sensor of Neurodegeneration
2018
CD22 blockade restores homeostatic microglial phagocytosis in ageing brains
2019 StandoutNatureNobel
Interleukin-12 and the regulation of innate resistance and adaptive immunity
2003 Standout
Cytoskeletal rearrangement during migration and activation of T lymphocytes
1999
Structure of the ERM Protein Moesin Reveals the FERM Domain Fold Masked by an Extended Actin Binding Tail Domain
2000
Expression level, subcellular distribution and Rho-GDI binding affinity of merlin in comparison with ezrin/radixin/moesin proteins
1999
ERM proteins and merlin: integrators at the cell cortex
2002 Standout
A Dual Involvement of the Amino-terminal Domain of Ezrin in F- and G-actin Binding
1997
Recognition of microorganisms and activation of the immune response
2007 StandoutNature
Identification and functional analysis of the ezrin-binding site in the hyaluronan receptor, CD44
1998
Endothelial-Leukocyte Adhesion Molecules
1993
DC-SIGN–ICAM-2 interaction mediates dendritic cell trafficking
2000
Heterogeneous expression of the triggering receptor expressed on myeloid cells‐2 on adult murine microglia
2002
Oligomeric Nature of the Integral Membrane Protein Stomatin
1998
Transforming growth factor-β induces development of the TH17 lineage
2006 StandoutNature
TREMs in the immune system and beyond
2003
Identification of a 55-kDa Ezrin-Related Protein That Induces Cytoskeletal Changes and Localizes to the Nucleolus
1999
Leukocyte-Endothelial Cell Interactions – Lessons from Knockout Mice
1999
Cytotoxicity mediated by T cells and natural killer cells is greatly impaired in perforin-deficient mice
1994 StandoutNature
Osteopetrosis and thalamic hypomyelinosis with synaptic degeneration in DAP12-deficient mice
2003
Human Natural Killer Cells: Origin, Clonality, Specificity, and Receptors
1993
Transmembrane Pickets Connect Cyto- and Pericellular Skeletons Forming Barriers to Receptor Engagement
2018 StandoutNobel
Dendritic cells acquire antigen from apoptotic cells and induce class I-restricted CTLs
1998 StandoutNature
Exclusion of CD43 from the Immunological Synapse Is Mediated by Phosphorylation-Regulated Relocation of the Cytoskeletal Adaptor Moesin
2001
Mutations in Two Genes Encoding Different Subunits of a Receptor Signaling Complex Result in an Identical Disease Phenotype
2002
MEC-2 regulates C. elegans DEG/ENaC channels needed for mechanosensation
2002 StandoutNatureNobel
Association of Ezrin with Intercellular Adhesion Molecule-1 and -2 (ICAM-1 and ICAM-2)
1998
Combined Natural Killer Cell and Dendritic Cell Functional Deficiency in KARAP/DAP12 Loss-of-Function Mutant Mice
2000
Microglia Promote Learning-Dependent Synapse Formation through Brain-Derived Neurotrophic Factor
2013 Standout
Biochemistry and molecular cell biology of diabetic complications
2001 StandoutNature
Direct Binding of the Na–H Exchanger NHE1 to ERM Proteins Regulates the Cortical Cytoskeleton and Cell Shape Independently of H+ Translocation
2000
Merlin: the neurofibromatosis 2 tumor suppressor
1999
A Systematic Screen for Dominant Second-Site Modifiers of Merlin/NF2 Phenotypes Reveals an Interaction With blistered/DSRF and scribbler
2001
A quick and simple method for the quantitation of lactate dehydrogenase release in measurements of cellular cytotoxicity and tumor necrosis factor (TNF) activity
1988
Phosphorylation of the β‐subunit of CD11/CD18 integrins by protein kinase C correlates with leukocyte adhesion
1991
Human natural interferon-α producing cells
1993
The Carboxyl-terminal Region of EBP50 Binds to a Site in the Amino-terminal Domain of Ezrin That Is Masked in the Dormant Molecule
1998
Cortical Actin Organization: Lessons from ERM (Ezrin/Radixin/Moesin) Proteins
1999
Moesin Interacts with the Cytoplasmic Region of Intercellular Adhesion Molecule-3 and Is Redistributed to the Uropod of T Lymphocytes during Cell Polarization
1997
DAP12-Deficient Mice Fail to Develop Autoimmunity Due to Impaired Antigen Priming
2000
Integrins
2002 Standout
Detection of perforin and granzyme A mRNA in infiltrating cells during infection of mice with lymphocytic choriomeningitis virus
1989
An Apical PDZ Protein Anchors the Cystic Fibrosis Transmembrane Conductance Regulator to the Cytoskeleton
1998
Structural basis of the membrane-targeting and unmasking mechanisms of the radixin FERM domain
2000
CD40 ligand on activated platelets triggers an inflammatory reaction of endothelial cells
1998 StandoutNature
Natural killer cells, viruses and cancer
2001
SH2 and SH3 Domains: Elements that Control Interactions of Cytoplasmic Signaling Proteins
1991 StandoutScience
Expression of adhesion molecules and chemotactic cytokines in cultured human mesothelial cells.
1992
Isolation of Putative Progenitor Endothelial Cells for Angiogenesis
1997 StandoutScience
Homotypic and heterotypic interaction of the neurofibromatosis 2 tumor suppressor protein merlin and the ERM protein ezrin
1999
Slc15a4, AP-3, and Hermansky-Pudlak syndrome proteins are required for Toll-like receptor signaling in plasmacytoid dendritic cells
2010 StandoutNobel
Dendritic cells require a systemic type I interferon response to mature and induce CD4+ Th1 immunity with poly IC as adjuvant
2009 StandoutNobel
The Nature of the Principal Type 1 Interferon-Producing Cells in Human Blood
1999 StandoutScience
Immunization with HIV Gag targeted to dendritic cells followed by recombinant New York vaccinia virus induces robust T-cell immunity in nonhuman primates
2011 StandoutNobel
The Staphylococcal Enterotoxins and Their Relatives
1990 StandoutScience
Cell Migration: Integrating Signals from Front to Back
2003 StandoutScience
Early protection against pathogenic virus infection at a mucosal challenge site after vaccination with attenuated simian immunodeficiency virus
2004 StandoutNobel
CD43 Interacts With Moesin and Ezrin and Regulates Its Redistribution to the Uropods of T Lymphocytes at the Cell-Cell Contacts
1998
RGD AND OTHER RECOGNITION SEQUENCES FOR INTEGRINS
1996 Standout
RhoA-Dependent Phosphorylation and Relocalization of ERM Proteins into Apical Membrane/Actin Protrusions in Fibroblasts
1998
Structural Analysis of Drosophila Merlin Reveals Functional Domains Important for Growth Control and Subcellular Localization
1998
Lymphocyte Homing and Homeostasis
1996 StandoutScience
Integrins: Versatility, modulation, and signaling in cell adhesion
1992 Standout
The C-type lectin SIGN-R1 mediates uptake of the capsular polysaccharide ofStreptococcus pneumoniaein the marginal zone of mouse spleen
2003 StandoutNobel
Clearance of apoptotic neurons without inflammation by microglial triggering receptor expressed on myeloid cells-2
2005 Standout
Ezrin Is an Effector of Hepatocyte Growth Factor–mediated Migration and Morphogenesis in Epithelial Cells
1997
Elevated TGF-β1 Secretion and Down-Modulation of NKG2D Underlies Impaired NK Cytotoxicity in Cancer Patients
2004
Comparable T helper 1 (Th1) and CD8 T-cell immunity by targeting HIV gag p24 to CD8 dendritic cells within antibodies to Langerin, DEC205, and Clec9A
2011 StandoutNobel
Leukocyte-endothelial adhesion molecules
1994 Standout
Rho-Kinase Phosphorylates COOH-terminal Threonines of Ezrin/Radixin/Moesin (ERM) Proteins and Regulates Their Head-to-Tail Association
1998
Ezrin links syndecan-2 to the cytoskeleton
2000
Rho-dependent and -independent activation mechanisms of ezrin/radixin/moesin proteins: an essential role for polyphosphoinositides in vivo
2002
New insights on the role of microglia in synaptic pruning in health and disease
2015
CD1d-Restricted and TCR-Mediated Activation of V α 14 NKT Cells by Glycosylceramides
1997 StandoutScience
Neural Science
2000 StandoutNobel
Ezrin/Radixin/Moesin (ERM) Proteins Bind to a Positively Charged Amino Acid Cluster in the Juxta-Membrane Cytoplasmic Domain of CD44, CD43, and ICAM-2
1998
Heterogeneity of presenile dementia with bone cysts (Nasu–Hakola disease)
2002
Foxp3+natural regulatory T cells preferentially form aggregates on dendritic cellsin vitroand actively inhibit their maturation
2008 StandoutNobel
The Cytoskeleton and Cell Signaling: Component Localization and Mechanical Coupling
1998
Cancer Treatment by Targeted Drug Delivery to Tumor Vasculature in a Mouse Model
1998 StandoutScience
IPC: Professional Type 1 Interferon-Producing Cells and Plasmacytoid Dendritic Cell Precursors
2004
Reversible Photocontrol of Biological Systems by the Incorporation of Molecular Photoswitches
2013 StandoutNobel
Selective Tropism of Lymphadenopathy Associated Virus (LAV) for Helper-Inducer T Lymphocytes
1984 StandoutScienceNobel
Lymphokine-activated killer cell phenomenon. Lysis of natural killer-resistant fresh solid tumor cells by interleukin 2-activated autologous human peripheral blood lymphocytes.
1982 Standout
Subsets of Patients with Aplastic Anemia Identified by Flow Microfluorometry
1985 StandoutNobel
Analysis of the mitogenic effects of toxic shock toxin on human peripheral blood mononuclear cells in vitro
1984
Ezrin, a plasma membrane–microfilament linker, signals cell survival through the phosphatidylinositol 3-kinase/Akt pathway
1999
Identification of Epi64, a Tbc/Rabgap Domain–Containing Microvillar Protein That Binds to the First PDZ Domain of Ebp50 and E3karp
2001
Precision glycocalyx editing as a strategy for cancer immunotherapy
2016 StandoutNobel
The roles of interdigitating cells and natural killer cells in the rapid rejection of allogeneic lymphocytes
1986
The Rapid Elimination of Allogeneic Lymphocytes: Relationship to Established Mechanisms of Immunity and to Lymphocyte Traffic
1983
The IL-2 Receptor β Chain (p70): Role in Mediating Signals for LAK, NK, and Proliferative Activities
1987 Science
Mucin MUC1 Is Seen in Cell Surface Protrusions Together with Ezrin in Immunoelectron Tomography and is Concentrated at Tips of Filopodial Protrusions in MCF-7 Breast Carcinoma Cells
2001
Circulating Activated Suppressor T Lymphocytes in Aplastic Anemia
1985
TRANSFORMING GROWTH FACTOR-β REGULATION OF IMMUNE RESPONSES
2005 Standout
Impaired Differentiation of Osteoclasts in TREM-2–deficient Individuals
2003
The p75 peptide is the receptor for interleukin 2 expressed on large granular lymphocytes and is responsible for the interleukin 2 activation of these cells.
1987
The Nf2 tumor suppressor gene product is essential for extraembryonic development immediately prior to gastrulation.
1997
ERM-Merlin and EBP50 Protein Families in Plasma Membrane Organization and Function
2000
Integrin-mediated cell adhesion: the extracellular face.
1994
Characterization of Human Palladin, a Microfilament-associated Protein
2001
Regulation of F-Actin Binding to Platelet Moesin In Vitro by Both Phosphorylation of Threonine 558 and Polyphosphatidylinositides
1999
Phenotypic diversity within clones of human normal t cells
1983
Multiple Defects of Immune Cell Function in Mice with Disrupted Interferon-γ Genes
1993 StandoutScience
Selective rejection of H–2-deficient lymphoma variants suggests alternative immune defence strategy
1986 StandoutNature
Place Cells and Place Recognition Maintained by Direct Entorhinal-Hippocampal Circuitry
2002 StandoutScienceNobel
Kinetics of IL-2 and interferon-γ production, expression of IL-2 receptors, and cell proliferation in human mononuclear cells exposed to staphylococcal enterotoxin A
1985
DAP12/TREM2 Deficiency Results in Impaired Osteoclast Differentiation and Osteoporotic Features
2003
Repair of DNA–polypeptide crosslinks by human excision nuclease
2006 StandoutNobel
Lymphocyte subsets in tumour of patients with undifferentiated nasopharyngeal carcinoma: presence of lymphocytes with the phenotype of activated T cells
1987
Three determinants in ezrin are responsible for cell extension activity.
1997
vav, a novel human oncogene derived from a locus ubiquitously expressed in hematopoietic cells.
1989
Purification and characterization of a cytolytic pore-forming protein from granules of cloned lymphocytes with natural killer activity
1986
Generation of an inhibitory circuit involving CD8+ T cells, IL-2, and NK cell-derived TGF-beta: contrasting effects of anti-CD2 and anti-CD3.
1998
CNS manifestations of Nasu–Hakola disease
2001
Interleukin-2: Inception, Impact, and Implications
1988 StandoutScience
Works of Tuomo Timonen being referenced
Loss-of-function mutations in TYROBP (DAP12) result in a presenile dementia with bone cysts
2000
The ezrin protein family: membrane-cytoskeleton interactions and disease associations
1997
ICAM-2 redistributed by ezrin as a target for killer cells
1996 Nature
Regulation of Natural Killer Cell Activity by Transforming Growth Factor‐β and Prostaglandin E2
1993
Leukocyte‐Cell Adhesion: A Molecular Process Fundamental in Leukocyte Physiology
1990
The expression of human intercellular adhesion molecule‐2 is refractory to inflammatory cytokines
1991
A leukocyte integrin binding peptide from intercellular adhesion molecule-2 stimulates T cell adhesion and natural killer cell activity.
1993
Isolation of human and rat natural killer cells
1982
Determination of surface antigens on highly purified human NK cells by flow cytometry with monoclonal antibodies.
1981
Isolation of human NK cells by density gradient centrifugation
1980
Production of plasminogen activator by human natural killer cells. Large granular lymphocytes.
1984
Natural killer cells are responsible for the interferon production induced in human lymphocytes by tumor cell contact
1980
Analysis by a single cell cytotoxicity assay of natural killer (NK) cells frequencies among human large granular lymphocytes and of the effects of interferon on their activity.
1982
Characteristics of human large granular lymphocytes and relationship to natural killer and K cells
1981
Positive self regulation of cytotoxicity in human natural killer cells by production of interferon upon exposure to influenza and herpes viruses.
1982
Morphological and Functional Characterization of Isolated Effector Cells Responsible for Human Natural Killer Activity to Fetal Fibroblasts and to Cultured Cell Line Targets
1979
A monoclonal antibody to the human leukocyte adhesion molecule intercellular adhesion molecule-2. Cellular distribution and molecular characterization of the antigen
1991
IFN-α and IL-18 synergistically enhance IFN-γ production in human NK cells: differential regulation of Stat4 activation and IFN-γ gene expression by IFN-α and IL-12
2001
Natural killer cell activity in the rat. Analysis of effector cell morphology and effects of interferon on natural killer cell function in the athymic (nude) rat
1982