Standout Papers
- MX2 is an interferon-induced inhibitor of HIV-1 infection (2013)
- Identification of Interferon-Stimulated Genes with Antiretroviral Activity (2016)
- Inhibition of HIV-1 Particle Assembly by 2′,3′-Cyclic-Nucleotide 3′-Phosphodiesterase (2012)
- Tetherin inhibits retrovirus release and is antagonized by HIV-1 Vpu (2008)
Citation Impact
Citing Papers
Cyclic GMP-AMP Synthase Is a Cytosolic DNA Sensor That Activates the Type I Interferon Pathway
2012 StandoutScience
Role of LBPA and Alix in Multivesicular Liposome Formation and Endosome Organization
2004 StandoutScienceNobel
High-Throughput Mapping of a Dynamic Signaling Network in Mammalian Cells
2005 StandoutScience
Broad role for YBX1 in defining the small noncoding RNA composition of exosomes
2017 Nobel
Maturation-Dependent HIV-1 Surface Protein Redistribution Revealed by Fluorescence Nanoscopy
2012 StandoutScienceNobel
Caenorhabditis elegans ADAR editing and the ERI-6/7/MOV10 RNAi pathway silence endogenous viral elements and LTR retrotransposons
2020 StandoutNobel
Structure of the HIV-1 RNA packaging signal
2015 Science
Design and Evolution of New Catalytic Activity with an Existing Protein Scaffold
2006 Science
Proteomics of HCV virions reveals an essential role for the nucleoporin Nup98 in virus morphogenesis
2016 StandoutNobel
LGP2 is a positive regulator of RIG-I– and MDA5-mediated antiviral responses
2010
In vitro reconstitution of the ordered assembly of the endosomal sorting complex required for transport at membrane-bound HIV-1 Gag clusters
2012
The IFITM Proteins Inhibit HIV-1 Infection
2010
Identification of interferon-stimulated genes that attenuate Ebola virus infection
2020 StandoutNobel
Cellular Binding of Hepatitis C Virus Envelope Glycoprotein E2 Requires Cell Surface Heparan Sulfate
2003
Discovery and functional interrogation of SARS-CoV-2 RNA-host protein interactions
2021 StandoutNobel
Sensitivity to BST-2 restriction correlates with Orthobunyavirus host range
2017
A novel combined RNA-protein interaction analysis distinguishes HIV-1 Gag protein binding sites from structural change in the viral RNA leader
2015
Construction of novel repeat proteins with rigid and predictable structures using a shared helix method
2017
Assembly and Architecture of HIV
2011
Assisted Evolution Enables HIV-1 to Overcome a High TRIM5α-Imposed Genetic Barrier to Rhesus Macaque Tropism
2013
The Crystal Structure of Atg3, an Autophagy-related Ubiquitin Carrier Protein (E2) Enzyme that Mediates Atg8 Lipidation
2007 StandoutNobel
Structure and functional interactions of the Tsg101 UEV domain
2002
Specificity in Signal Transduction
2004
Intrinsic Cellular Defenses against Human Immunodeficiency Viruses
2012
Influenza Virus Partially Counteracts Restriction Imposed by Tetherin/BST-2
2012
SARS-CoV-2 Cell Entry Depends on ACE2 and TMPRSS2 and Is Blocked by a Clinically Proven Protease Inhibitor
2020 Standout
Zinc-Finger Antiviral Protein Inhibits XMRV Infection
2012
The cytoplasmic body component TRIM5α restricts HIV-1 infection in Old World monkeys
2004 StandoutNature
Evolutionary conflicts between viruses and restriction factors shape immunity
2012
ZAP’s stress granule localization is correlated with its antiviral activity and induced by virus replication
2019 StandoutNobel
Completion of the entire hepatitis C virus life cycle in genetically humanized mice
2013 StandoutNatureNobel
Selection and evolution of enzymes from a partially randomized non-catalytic scaffold
2007 StandoutNatureNobel
Assembly and Budding of Ebolavirus
2006
Human ADAR1 Prevents Endogenous RNA from Triggering Translational Shutdown
2018 StandoutNobel
Receptor downregulation and multivesicular-body sorting
2002
Cell Signaling by Receptor Tyrosine Kinases
2010 Standout
Architects of assembly: roles of Flaviviridae non-structural proteins in virion morphogenesis
2008 StandoutNobel
The Neuronal Gene Arc Encodes a Repurposed Retrotransposon Gag Protein that Mediates Intercellular RNA Transfer
2018
Unraveling the functions of plasmacytoid dendritic cells during viral infections, autoimmunity, and tolerance
2010
Designed proteins induce the formation of nanocage-containing extracellular vesicles
2016 Nature
Intra-endosomal membrane traffic
2006
Pattern Recognition Receptors and Inflammation
2010 Standout
The intracellular plasma membrane-connected compartment in the assembly of HIV-1 in human macrophages
2016
Inhibition of Japanese encephalitis virus infection by the host zinc-finger antiviral protein
2018
Expanding the Enzyme Universe: Accessing Non‐Natural Reactions by Mechanism‐Guided Directed Evolution
2015 StandoutNobel
SAMHD1 is the dendritic- and myeloid-cell-specific HIV-1 restriction factor counteracted by Vpx
2011 Nature
Structural basis of ubiquitylation
2002
Influenza virus activates inflammasomes via its intracellular M2 ion channel
2010
HIV-1 Assembly, Budding, and Maturation
2012
AIP1/ALIX Is a Binding Partner for HIV-1 p6 and EIAV p9 Functioning in Virus Budding
2003
Influenza virus is not restricted by tetherin whereas influenza VLP production is restricted by tetherin
2011
Ebola virus entry requires the cholesterol transporter Niemann–Pick C1
2011 StandoutNature
A Serpin Shapes the Extracellular Environment to Prevent Influenza A Virus Maturation
2015 StandoutNobel
The Broad-Spectrum Antiviral Protein ZAP Restricts Human Retrotransposition
2015
The Protein Network of HIV Budding
2003
Intrinsic Immunity Shapes Viral Resistance of Stem Cells
2017 StandoutNobel
Double-labelled HIV-1 particles for study of virus–cell interaction
2006
Canine Hepacivirus NS3 Serine Protease Can Cleave the Human Adaptor Proteins MAVS and TRIF
2012
Human MX2 is an interferon-induced post-entry inhibitor of HIV-1 infection
2013 Nature
Nef Proteins from Simian Immunodeficiency Viruses Are Tetherin Antagonists
2009
IFNβ-dependent increases in STAT1, STAT2, and IRF9 mediate resistance to viruses and DNA damage
2013 StandoutNobel
Moloney Leukemia Virus 10 (MOV10) Protein Inhibits Retrovirus Replication
2010
The Assembly of Ebola Virus Nucleocapsid Requires Virion-Associated Proteins 35 and 24 and Posttranslational Modification of Nucleoprotein
2002
A diverse range of gene products are effectors of the type I interferon antiviral response
2011 StandoutNatureNobel
Palmitoylome profiling reveals S-palmitoylation–dependent antiviral activity of IFITM3
2010
Membrane curvature and mechanisms of dynamic cell membrane remodelling
2005 StandoutNature
Glypican-1 identifies cancer exosomes and detects early pancreatic cancer
2015 StandoutNature
Endogenous retroviruses: acquisition, amplification and taming of genome invaders
2013
Convergent Evolution of Escape from Hepaciviral Antagonism in Primates
2012
BST-2/tetherin: Structural biology, viral antagonism, and immunobiology of a potent host antiviral factor
2012
A genetically humanized mouse model for hepatitis C virus infection
2011 StandoutNatureNobel
IFITM Proteins Restrict Viral Membrane Hemifusion
2013
The glycoprotein of vesicular stomatitis virus promotes release of virus-like particles from tetherin-positive cells
2017
Structural Basis for Endosomal Targeting by the Bro1 Domain
2005
Specificities of secretion and uptake of exosomes and other extracellular vesicles for cell-to-cell communication
2018 Standout
The ESCRT Pathway
2011
Interferon-stimulated genes and their antiviral effector functions
2011 StandoutNobel
Interferon-γ Inhibits Ebola Virus Infection
2015
HIV-1 assembly, release and maturation
2015
The biogenesis of multivesicular endosomes
2004
The emerging shape of the ESCRT machinery
2007
Species-Specific Activity of SIV Nef and HIV-1 Vpu in Overcoming Restriction by Tetherin/BST2
2009
Exosomes: composition, biogenesis and function
2002 Standout
Intrinsic antiviral immunity
2012
Interferon-Inducible Cholesterol-25-Hydroxylase Broadly Inhibits Viral Entry by Production of 25-Hydroxycholesterol
2012
Inflammasomes in health and disease
2012 StandoutNature
Molecular mechanism to recruit galectin-3 into multivesicular bodies for polarized exosomal secretion
2018
Slc15a4, AP-3, and Hermansky-Pudlak syndrome proteins are required for Toll-like receptor signaling in plasmacytoid dendritic cells
2010 StandoutNobel
Characterization of Novel Splice Variants of Zinc Finger Antiviral Protein (ZAP)
2019 StandoutNobel
The structural and energetic basis for high selectivity in a high-affinity protein-protein interaction
2010 StandoutNobel
Exosomes
2019 Standout
RTP4 inhibits IFN-I response and enhances experimental cerebral malaria and neuropathology
2020 StandoutNobel
Cellular inhibitors with Fv1-like activity restrict human and simian immunodeficiency virus tropism
2002
Imaging the interaction of HIV-1 genomes and Gag during assembly of individual viral particles
2009
Human ESCRT-II Complex and Its Role in Human Immunodeficiency Virus Type 1 Release
2006
Abrogation of postentry restriction of HIV-1-based lentiviral vector transduction in simian cells
2003
Enhanced HIV-1 immunotherapy by commonly arising antibodies that target virus escape variants
2014
Live-cell observation of cytosolic HIV-1 assembly onset reveals RNA-interacting Gag oligomers
2015
Ceramide Triggers Budding of Exosome Vesicles into Multivesicular Endosomes
2008 StandoutScience
Dengue reporter viruses reveal viral dynamics in interferon receptor-deficient mice and sensitivity to interferon effectors in vitro
2012 StandoutNobel
Tetherin-mediated restriction of filovirus budding is antagonized by the Ebola glycoprotein
2009
Formation and release of arrestin domain-containing protein 1-mediated microvesicles (ARMMs) at plasma membrane by recruitment of TSG101 protein
2012
Modeling host interactions with hepatitis B virus using primary and induced pluripotent stem cell-derived hepatocellular systems
2014 StandoutNobel
Characterization of nonprimate hepacivirus and construction of a functional molecular clone
2015 StandoutNobel
ATG Systems from the Protein Structural Point of View
2009 StandoutNobel
Distinct Roles for Tsg101 and Hrs in Multivesicular Body Formation and Inward Vesiculation
2006
Zinc-finger antiviral protein inhibits HIV-1 infection by selectively targeting multiply spliced viral mRNAs for degradation
2011
Interferon-Induced SCYL2 Limits Release of HIV-1 by Triggering PP2A-Mediated Dephosphorylation of the Viral Protein Vpu
2012
HIV-1–cellular interactions analyzed by single virus tracing
2008
Interferon-Stimulated Genes: A Complex Web of Host Defenses
2014 StandoutNobel
Lipid raft-associated protein sorting in exosomes
2003
Depletion of TSG101 forms a mammalian `Class E' compartment: a multicisternal early endosome with multiple sorting defects
2005
Opposing mechanisms involving RNA and lipids regulate HIV-1 Gag membrane binding through the highly basic region of the matrix domain
2010
Budding Capability of the Influenza Virus Neuraminidase Can Be Modulated by Tetherin
2011
Modular repeat protein sculpting using rigid helical junctions
2020 StandoutNobel
The biology , function , and biomedical applications of exosomes
2020 StandoutScience
The Envelope Gene of Transmitted HIV-1 Resists a Late Interferon Gamma-Induced Block
2017
THE ESCRT COMPLEXES: Structure and Mechanism of a Membrane-Trafficking Network
2006
Antagonism to and Intracellular Sequestration of Human Tetherin by the Human Immunodeficiency Virus Type 2 Envelope Glycoprotein
2009
Reconstitution of selective HIV-1 RNA packaging in vitro by membrane-bound Gag assemblies
2016 StandoutNobel
Defects in Human Immunodeficiency Virus Budding and Endosomal Sorting Induced by TSG101 Overexpression
2003
Dynamics of HIV-1 RNA Near the Plasma Membrane during Virus Assembly
2015
Interferon-Induced Cell Membrane Proteins, IFITM3 and Tetherin, Inhibit Vesicular Stomatitis Virus Infection via Distinct Mechanisms
2010
ESCRTs in membrane sealing
2018
Contribution of Ebola Virus Glycoprotein, Nucleoprotein, and VP24 to Budding of VP40 Virus-Like Particles
2004
Amyloid precursor protein (APP) traffics from the cell surface via endosomes for amyloid β (Aβ) production in the trans -Golgi network
2012 StandoutNobel
Interferon-Stimulated Gene (ISG)-Expression Screening Reveals the Specific Antibunyaviral Activity of ISG20
2018 StandoutNobel
ZAP, a CCCH-Type Zinc Finger Protein, Inhibits Porcine Reproductive and Respiratory Syndrome Virus Replication and Interacts with Viral Nsp9
2019
The Host RNAs in Retroviral Particles
2016
In vivo oligomerization and raft localization of Ebola virus protein VP40 during vesicular budding
2003
Structural basis for Zika envelope domain III recognition by a germline version of a recurrent neutralizing antibody
2020 StandoutNobel
The WD40 and FYVE domain containing protein 2 defines a class of early endosomes necessary for endocytosis
2006 StandoutNobel
Top-down design of protein architectures with reinforcement learning
2023 StandoutScienceNobel
Deficiency of Niemann-Pick Type C-1 Protein Impairs Release of Human Immunodeficiency Virus Type 1 and Results in Gag Accumulation in Late Endosomal/Lysosomal Compartments
2009
Vps27 recruits ESCRT machinery to endosomes during MVB sorting
2003
Genetic Dissection of the Host Tropism of Human-Tropic Pathogens
2015
HIV-1 RNA genome dimerizes on the plasma membrane in the presence of Gag protein
2015
Works of Trinity Zang being referenced
Tetherin inhibits retrovirus release and is antagonized by HIV-1 Vpu
2008 StandoutNature
The RING-CH Ligase K5 Antagonizes Restriction of KSHV and HIV-1 Particle Release by Mediating Ubiquitin-Dependent Endosomal Degradation of Tetherin
2010
Identification of Human VPS37C, a Component of Endosomal Sorting Complex Required for Transport-I Important for Viral Budding
2004
Species-Specific Activity of HIV-1 Vpu and Positive Selection of Tetherin Transmembrane Domain Variants
2009
Arabidopsis Glyoxalase II Contains a Zinc/Iron Binuclear Metal Center That Is Essential for Substrate Binding and Catalysis
2001
MX2 is an interferon-induced inhibitor of HIV-1 infection
2013 StandoutNatureNobel
Tetherin Inhibits HIV-1 Release by Directly Tethering Virions to Cells
2009
HIV-1 and Ebola virus encode small peptide motifs that recruit Tsg101 to sites of particle assembly to facilitate egress
2001
Inhibition of HIV-1 Particle Assembly by 2′,3′-Cyclic-Nucleotide 3′-Phosphodiesterase
2012 StandoutNobel
Global Changes in the RNA Binding Specificity of HIV-1 Gag Regulate Virion Genesis
2014
Identification of Interferon-Stimulated Genes with Antiretroviral Activity
2016 StandoutNobel
Analysis of the human immunodeficiency virus-1 RNA packageome
2016
CG dinucleotide suppression enables antiviral defence targeting non-self RNA
2017 Nature
Matrix-Induced Inhibition of Membrane Binding Contributes to Human Immunodeficiency Virus Type 1 Particle Assembly Defects in Murine Cells
2005
Structural insight into the mechanisms of enveloped virus tethering by tetherin
2010
Envelope-Dependent, Cyclophilin-Independent Effects of Glycosaminoglycans on Human Immunodeficiency Virus Type 1 Attachment and Infection
2002
Role of ESCRT-I in Retroviral Budding
2003
Host and Viral Determinants of Mx2 Antiretroviral Activity
2014
Broad-Spectrum Inhibition of Retroviral and Filoviral Particle Release by Tetherin
2008