Citation Impact
Citing Papers
A Novel Tankyrase Small-Molecule Inhibitor Suppresses APC Mutation–Driven Colorectal Tumor Growth
2013
Structural inference of native and partially folded RNA by high-throughput contact mapping
2008 StandoutNobel
Structural characterizations of nonpeptidic thiadiazole inhibitors of matrix metalloproteinases reveal the basis for stromelysin selectivity
1998
Expression, Assay, and Structure of the Extracellular Domain of Murine Carbonic Anhydrase XIV
2004
Structure and function of matrix metalloproteinases and TIMPs
2006 Standout
Mutant carbonic anhydrase 4 impairs pH regulation and causes retinal photoreceptor degeneration
2004
Carbonic Anhydrase Activators. Activation of Isozymes I, II, IV, VA, VII, and XIV with L ‐ and D ‐Histidine and Crystallographic Analysis of Their Adducts with Isoform II: Engineering Proton‐Transfer Processes within the Active Site of an Enzyme
2006
Activation of Atypical Protein Kinase C ζ by Caspase Processing and Degradation by the Ubiquitin-Proteasome System
2000 StandoutNobel
Solution structure of the catalytic domain of human stromelysin complexed with a hydrophobic inhibitor
1995
The β Sliding Clamp Binds to Multiple Sites within MutL and MutS
2006 StandoutNobel
Movement of the Decoding Region of the 16 S Ribosomal RNA Accompanies tRNA Translocation
2000 StandoutNobel
Carbonic Anhydrase Inhibitors: Binding of Indanesulfonamides to the Human Isoform II
2007
Direct Visualization of Asymmetric Adenine Nucleotide-Induced Conformational Changes in MutLα
2008 StandoutNobel
X-ray structure of a hydroxamate inhibitor complex of stromelysin catalytic domain and its comparison with members of the zinc metalloproteinase superfamily
1996
Comparative genomics and evolution of proteins involved in RNA metabolism
2002
Dual selection enhances the signaling specificity of a variant of the quorum-sensing transcriptional activator LuxR
2006 StandoutNobel
Structure, mechanism, and inhibition of histone deacetylases and related metalloenzymes
2011
Substrate Specificities of Caspase Family Proteases
1997
Role of Domains 4 and 5 in Elongation Factor G Functions on the Ribosome
2000
Role of metal ions in the hydrolysis reaction catalyzed by RNase P RNA from Bacillus subtilis
1999
Structure of the topoisomerase VI-B subunit: implications for type II topoisomerase mechanism and evolution
2002
Crystal structure of human carbonic anhydrase XIII and its complex with the inhibitor acetazolamide
2008
Stromelysin‐1: Three‐dimensional structure of the inhibited catalytic domain and of the C‐truncated proenzyme
1995
Serum antibodies to carbonic anhydrase IV in patients with autoimmune pancreatitis
2005
Zinc coordination sphere in biochemical zinc sites
2001
Anchor extension: a structure-guided approach to design cyclic peptides targeting enzyme active sites
2021 StandoutNobel
Retinitis pigmentosa
2006 Standout
X-ray Structures of Human Neutrophil Collagenase Complexed with Peptide Hydroxamate and Peptide Thiol Inhibitors. Implications for Substrate Binding and Rational Drug Design
1995 Nobel
Empirical scoring functions: I. The development of a fast empirical scoring function to estimate the binding affinity of ligands in receptor complexes
1997
Localization of L11 protein on the ribosome and elucidation of its involvement in EF-G-dependent translocation
2001 StandoutNobel
Matrix Metalloproteinases: Regulators of the Tumor Microenvironment
2010 Standout
Carbonic anhydrases: novel therapeutic applications for inhibitors and activators
2008 Standout
Eukaryotic ribonuclease P: Increased complexity to cope with the nuclear pre-tRNA pathway
2001
Carbonic anhydrase inhibitors: X-ray crystallographic studies for the binding of 5-amino-1,3,4-thiadiazole-2-sulfonamide and 5-(4-amino-3-chloro-5-fluorophenylsulfonamido)-1,3,4-thiadiazole-2-sulfonamide to human isoform II
2006
Carbonic anhydrase inhibitors
2002 Standout
Carbonic anhydrase inhibitors: Binding of an antiglaucoma glycosyl-sulfanilamide derivative to human isoform II and its consequences for the drug design of enzyme inhibitors incorporating sugar moieties
2007
Insights into RNA Biology from an Atlas of Mammalian mRNA-Binding Proteins
2012 Standout
Structural analysis of inhibitor binding to human carbonic anhydrase II
1998
A novel loop-loop recognition motif in the yeast ribosomal protein L30 autoregulatory RNA complex.
1999
Crystal structure of the C183S/C217S mutant of human CA VII in complex with acetazolamide
2010
Interactions with Aromatic Rings in Chemical and Biological Recognition
2003 Standout
The metzincins — Topological and sequential relations between the astacins, adamalysins, serralysins, and matrixins (collagenases) define a super family of zinc‐peptidases
1995
The Helping Hand of Collagenase-3 (MMP-13): 2.7 Å Crystal Structure of its C-terminal Haemopexin-like Domain
1996
Comparison of the structure of human recombinant short form stromelysin by multidimensional heteronuclear NMR and X-ray crystallography
1996
Specific Interaction between EF-G and RRF and Its Implication for GTP-Dependent Ribosome Splitting into Subunits
2007 StandoutNobel
IgG4-related disease
2014 Standout
Crystal Structures of Recombinant 19-kDa Human Fibroblast Collagenase Complexed to Itself
1994
The chemical repertoire of natural ribozymes
2002 StandoutNatureNobel
A metalloproteinase disintegrin that releases tumour-necrosis factor-α from cells
1997 StandoutNature
Structures of modified eEF2·80S ribosome complexes reveal the role of GTP hydrolysis in translocation
2007 StandoutNobel
Visualizing induced fit in early assembly of the human signal recognition particle.
2001
The MutL ATPase Is Required for Mismatch Repair
2000 StandoutNobel
Structural features of a superfamily of zinc-endopeptidases: the metzincins
1995
A helping hand for collagenases: the haemopexin-like domain
1995
Crystal Structure and ATPase Activity of MutL
1998
Carbonic anhydrases as targets for medicinal chemistry
2007
Caspases: Intracellular Signaling by Proteolysis
1997 Standout
Crystal structures of matrilysin-inhibitor complexes
1995
In Situ Click Chemistry: Enzyme‐Generated Inhibitors of Carbonic Anhydrase II
2004 StandoutNobel
Wnt/β-Catenin Signaling, Disease, and Emerging Therapeutic Modalities
2017 Standout
Molecular Modeling of the Three-dimensional Structure of the Bacterial RNase P Holoenzyme
2002
Matrix Metalloproteinases
1999 Standout
Future challenges facing the development of specific active-site-directed synthetic inhibitors of MMPs
2004
Zinc enzymes
1998
Iron-Catalyzed Reactions in Organic Synthesis
2004 Standout
Protein Surface-Assisted Enhancement in the Binding Affinity of an Inhibitor for Recombinant Human Carbonic Anhydrase-II
2004
Photo-induced unfolding and inactivation of bovine carbonic anhydrase in the presence of a photoresponsive surfactant
2009
NUC-1, aCaenorhabditis elegansDNase II homolog, functions in an intermediate step of DNA degradation during apoptosis
2000 StandoutNobel
Molecular Recognition of Protein−Ligand Complexes: Applications to Drug Design
1997 Standout
The Complete Atomic Structure of the Large Ribosomal Subunit at 2.4 Å Resolution
2000 StandoutScienceNobel
Eukaryotic Ribonuclease P: A Plurality of Ribonucleoprotein Enzymes
2002
Multicopper Oxidases and Oxygenases
1996 Standout
A Survey of the Role of Noncovalent Sulfur Interactions in Drug Design
2015
Review Oncologic, Endocrine & Metabolic: Recent developments in matrix metalloproteinase inhibitors
1995
Exploration of Structured Symmetric Cyclic Peptides as Ligands for Metal-Organic Frameworks
2022 StandoutNobel
Structural and Functional Aspects of Metal Sites in Biology
1996 Standout
Human matrix metalloproteinase specificity studies using collagen sequence-based synthetic peptides
1996
Potent and selective inhibitors of gelatinase-A 2. carboxylic and phosphonic acid derivatives
1994
Glide: A New Approach for Rapid, Accurate Docking and Scoring. 1. Method and Assessment of Docking Accuracy
2004 Standout
Metabolic reprogramming by HIF-1 promotes the survival of bone marrow–derived angiogenic cells in ischemic tissue
2011 StandoutNobel
Ultrahigh Resolution Crystal Structures of Human Carbonic Anhydrases I and II Complexed with “Two-Prong” Inhibitors Reveal the Molecular Basis of High Affinity
2006
The Origin of Chalcogen-Bonding Interactions
2017 Standout
DNA Mismatch Repair: Functions and Mechanisms
2005 StandoutNobel
Stereoselective Cyclopropanation Reactions
2003 Standout
Recent Advances in Zinc Enzymology
1996 Nobel
Carbonic Anhydrase Inhibitors: Stacking with Phe131 Determines Active Site Binding Region of Inhibitors As Exemplified by the X-ray Crystal Structure of a Membrane-Impermeant Antitumor Sulfonamide Complexed with Isozyme II
2005
Carbonic anhydrase inhibitors and their therapeutic potential
2000
Fluorescent Sensors for Measuring Metal Ions in Living Systems
2014 Standout
Matrix metalloproteinases: structures, evolution, and diversification
1998
Coordinatively Unsaturated Metal Centers in the Extended Porous Framework of Zn3(BDC)3·6CH3OH (BDC = 1,4-Benzenedicarboxylate)
1998 StandoutNobel
Reversible Photocontrol of Biological Systems by the Incorporation of Molecular Photoswitches
2013 StandoutNobel
Crystal structure of the catalytic domain of the tumor-associated human carbonic anhydrase IX
2009
Successful Virtual Screening for Novel Inhibitors of Human Carbonic Anhydrase: Strategy and Experimental Confirmation
2002
Carbonic Anhydrase Inhibitors: Clash with Ala65 as a Means for Designing Inhibitors with Low Affinity for the Ubiquitous Isozyme II, Exemplified by the Crystal Structure of the Topiramate Sulfamide Analogue
2006
The Structure of the Ribosome with Elongation Factor G Trapped in the Posttranslocational State
2009 StandoutScienceNobel
Crystal structure of the dimeric extracellular domain of human carbonic anhydrase XII, a bitopic membrane protein overexpressed in certain cancer tumor cells
2001
Iron-Sulfur Clusters: Nature's Modular, Multipurpose Structures
1997 StandoutScience
Matrix Metalloproteinase Inhibitors and Cancer—Trials and Tribulations
2002 StandoutScience
Polyamines Inhibit Carbonic Anhydrases by Anchoring to the Zinc-Coordinated Water Molecule
2010
Review Article
2004
5'-Triphosphate RNA Is the Ligand for RIG-I
2006 StandoutScience
Hydroxamate inhibitors of the matrix metallo-proteinases (MMPs) containing novel P1′ heteroatom based modifications
1995
The process of mRNA–tRNA translocation
2007 StandoutNobel
Directed Evolution of the Promiscuous Esterase Activity of Carbonic Anhydrase II
2005
Carbonic Anhydrase as a Model for Biophysical and Physical-Organic Studies of Proteins and Protein−Ligand Binding
2008
Synthesis of conformationally constrained potential inhibitors of mammalian metalloproteinases
1997
Design and Therapeutic Application of Matrix Metalloproteinase Inhibitors
1999
Matrix metalloproteases: Structure-based drug discovery targets
1995
Mechanistic Studies on Synthetic Fe−S-Based Clusters and Their Relevance to the Action of Nitrogenases
2005 StandoutNobel
Structural Insights Into the Signal Recognition Particle
2004 StandoutNobel
Structural Aspects of Isozyme Selectivity in the Binding of Inhibitors to Carbonic Anhydrases II and IV
2002
Structural Analysis of Charge Discrimination in the Binding of Inhibitors to Human Carbonic Anhydrases I and II
2007
Pathogenesis of retinitis pigmentosa associated with apoptosis-inducing mutations in carbonic anhydrase IV
2009
Metals in Neurobiology: Probing Their Chemistry and Biology with Molecular Imaging
2008 Standout
Recent advances in matrix metalloproteinase inhibitor research
1996
Multiple Binding Modes of Inhibitors to Carbonic Anhydrases: How to Design Specific Drugs Targeting 15 Different Isoforms?
2012 Standout
Works of Travis Stams being referenced
Structure of human neutrophil collagenase reveals large S1′ specificity pocket
1994
X-ray crystallographic studies of mammalian carbonic anhydrase isozymes
2000
Human HDAC isoform selectivity achieved via exploitation of the acetate release channel with structurally unique small molecule inhibitors
2011
Production, purification, and crystallization of human interleukin‐1β converting enzyme derived from an Escherichia coli expression system
1995
Structures of murine carbonic anhydrase IV and human carbonic anhydrase II complexed with brinzolamide: Molecular basis of isozyme‐drug discrimination
1998
Ribonuclease P Protein Structure: Evolutionary Origins in the Translational Apparatus
1998 Science
[1,2,4]Triazol-3-ylsulfanylmethyl)-3-phenyl-[1,2,4]oxadiazoles: Antagonists of the Wnt Pathway That Inhibit Tankyrases 1 and 2 via Novel Adenosine Pocket Binding
2012
Protein component of the ribozyme ribonuclease P alters substrate recognition by directly contacting precursor tRNA
1998
Crystal structure of the secretory form of membrane-associated human carbonic anhydrase IV at 2.8-Å resolution
1996