Citation Impact
Citing Papers
Histone demethylase KDM6A directly senses oxygen to control chromatin and cell fate
2019 StandoutScienceNobel
Chromosomal Instability Confers Intrinsic Multidrug Resistance
2011
Triggering a Cell Shape Change by Exploiting Preexisting Actomyosin Contractions
2012 StandoutScienceNobel
Sustained expression of microRNA-155 in hematopoietic stem cells causes a myeloproliferative disorder
2008 Nobel
Conversion of 5-Methylcytosine to 5-Hydroxymethylcytosine in Mammalian DNA by MLL Partner TET1
2009 StandoutScience
Functional Genomic Analysis of RNA Interference in C. elegans
2005 StandoutScienceNobel
Lysine Acetylation Targets Protein Complexes and Co-Regulates Major Cellular Functions
2009 StandoutScience
Recurrent Fusion of TMPRSS2 and ETS Transcription Factor Genes in Prostate Cancer
2005 StandoutScience
Using RNA interference to identify genes required for RNA interference
2002
High burden and pervasive positive selection of somatic mutations in normal human skin
2015 StandoutScience
Diagnosis and management of acute myeloid leukemia in adults: recommendations from an international expert panel, on behalf of the European LeukemiaNet
2009 Standout
Induction of interferon-stimulated gene expression and antiviral responses require protein deacetylase activity
2004 StandoutNobel
Projection of an Immunological Self Shadow Within the Thymus by the Aire Protein
2002 StandoutScience
Evolution of the Cancer Stem Cell Model
2014 Standout
Human PLU-1 Has Transcriptional Repression Properties and Interacts with the Developmental Transcription Factors BF-1 and PAX9
2003
Mutational Landscape of Basal Cell Carcinomas by Whole-Exome Sequencing
2013
Pan-cancer patterns of somatic copy number alteration
2013
RING fingers and B-boxes: zinc-binding protein-protein interaction domains
1998
The cytoplasmic body component TRIM5α restricts HIV-1 infection in Old World monkeys
2004 StandoutNature
Oncogenic kinase signalling
2001 StandoutNature
Loss of LIN-35, the Caenorhabditis elegansortholog of the tumor suppressor p105Rb, results in enhanced RNA interference
2006 StandoutNobel
Epigenetics in human disease and prospects for epigenetic therapy
2004 StandoutNature
RNAi screen identifies Brd4 as a therapeutic target in acute myeloid leukaemia
2011 StandoutNature
NOTCH1 Mutations Occur Early during Cutaneous Squamous Cell Carcinogenesis
2014
Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism
1998 StandoutNature
Identification of small RNA pathway genes using patterns of phylogenetic conservation and divergence
2012 StandoutNatureNobel
Inactivating mutations of the histone methyltransferase gene EZH2 in myeloid disorders
2010
Genome-scale transcriptional activation by an engineered CRISPR-Cas9 complex
2014 StandoutNature
Covalent histone modifications — miswritten, misinterpreted and mis-erased in human cancers
2010
The RING finger domain: a recent example of a sequence—structure family
1996
Specific small nucleolar RNA expression profiles in acute leukemia
2012
Distant metastasis occurs late during the genetic evolution of pancreatic cancer
2010 StandoutNature
High-Resolution Profiling of Histone Methylations in the Human Genome
2007 Standout
A soma-to-germline transformation in long-lived Caenorhabditis elegans mutants
2009 StandoutNatureNobel
High throughput digital quantification of mRNA abundance in primary human acute myeloid leukemia samples
2009
The Epigenomics of Cancer
2007 Standout
The SWI/SNF complex — chromatin and cancer
2004
Relapsed childhood acute lymphoblastic leukaemia
2013
Cancer stem cells: Back to Darwin?
2010
The Endocannabinoid System as an Emerging Target of Pharmacotherapy
2006 Standout
DANCE, a Novel Secreted RGD Protein Expressed in Developing, Atherosclerotic, and Balloon-injured Arteries
1999 StandoutNobel
Solution structure of the nonmethyl‐CpG‐binding CXXC domain of the leukaemia‐associated MLL histone methyltransferase
2006
Trans-splicing in C. elegans generates the negative RNAi regulator ERI-6/7
2008 StandoutNatureNobel
Somatic misexpression of germline P granules and enhanced RNA interference in retinoblastoma pathway mutants
2005 StandoutNatureNobel
A Temporarily Distinct Subpopulation of Slow-Cycling Melanoma Cells Is Required for Continuous Tumor Growth
2010
The glioma-amplified sequence 41 gene (GAS41) is a direct Myb target gene
2004
Diverse Chromatin Remodeling Genes Antagonize the Rb-Involved SynMuv Pathways in C. elegans
2006
Tumour heterogeneity and cancer cell plasticity
2013 StandoutNature
TET enzymes, TDG and the dynamics of DNA demethylation
2013 StandoutNature
miR-10a is aberrantly overexpressed in Nucleophosmin1 mutated acute myeloid leukaemia and its suppression induces cell death
2012
Positional cloning of the APECED gene
1997
The causes and consequences of genetic heterogeneity in cancer evolution
2013 StandoutNature
Histone deacetylase inhibitors: molecular mechanisms of action
2007
Genomic and Epigenomic Landscapes of Adult De Novo Acute Myeloid Leukemia
2013 Standout
Transformation of hematopoietic cells by BCR/ABL requires activation of a PI-3k/Akt-dependent pathway
1997
Prediction of molecular subtypes in acute myeloid leukemia based on gene expression profiling
2008
RNA interference
2002 StandoutNature
Leukaemogenesis: more than mutant genes
2009
High-resolution genomic profiling of chromosomal aberrations using Infinium whole-genome genotyping
2006
Prognostically Useful Gene-Expression Profiles in Acute Myeloid Leukemia
2004
Truncating mutations of hSNF5/INI1 in aggressive paediatric cancer
1998 StandoutNature
Clonal evolution in cancer
2012 StandoutNature
Identification and Characterization of BRDT: A Testis-Specific Gene Related to the Bromodomain Genes RING3 andDrosophila fsh
1997
Systematic analysis of genes required for synapse structure and function
2005 StandoutNatureNobel
Chimeric Antigen Receptor T Cells for Sustained Remissions in Leukemia
2014 Standout
A Novel Gene (PLU-1) Containing Highly Conserved Putative DNA/Chromatin Binding Motifs Is Specifically Up-regulated in Breast Cancer
1999
The Retinoblastoma Binding Protein RBP2 Is an H3K4 Demethylase
2007 StandoutNobel
Metastatic colonization by circulating tumour cells
2016 StandoutNature
Discovery and saturation analysis of cancer genes across 21 tumour types
2014 StandoutNature
Identification of acquired copy number alterations and uniparental disomies in cytogenetically normal acute myeloid leukemia using high-resolution single-nucleotide polymorphism analysis
2009
Linking the epigenetic ‘language’ of covalent histone modifications to cancer
2004
Genetic variegation of clonal architecture and propagating cells in leukaemia
2010 Nature
A Gain-of-Function Mutation of JAK2 in Myeloproliferative Disorders
2005 Standout
The Polycomb complex PRC2 and its mark in life
2011 StandoutNature
Evolution of human BCR–ABL1 lymphoblastic leukaemia-initiating cells
2011 Nature
MicroRNA Expression in Cytogenetically Normal Acute Myeloid Leukemia
2008
hDOT1L Links Histone Methylation to Leukemogenesis
2005
DNA profiling by arrayCGH in acute myeloid leukemia and myelodysplastic syndromes
2007
The Drosophila homolog of the human AF10 is an HP1‐interacting suppressor of position effect variegation
2001
Autochthonous tumors driven by Rb1 loss have an ongoing requirement for the RBP2 histone demethylase
2018 StandoutNobel
Interferon-stimulated transcription and innate antiviral immunity require deacetylase activity and histone deacetylase 1
2003
The mouse and human genes encoding the recognition component of the N-end rule pathway
1998 StandoutNobel
Development of Monocytes, Macrophages, and Dendritic Cells
2010 StandoutScience
The development of imatinib as a therapeutic agent for chronic myeloid leukemia
2004
Chromatin and oxygen sensing in the context of JmjC histone demethylases
2014
Mammalian mediator of transcriptional regulation and its possible role as an end-point of signal transduction pathways
1998 StandoutNobel
Does this have a familiar RING?
1996
The impact of FLT3 internal tandem duplication mutant level, number, size, and interaction with NPM1 mutations in a large cohort of young adult patients with acute myeloid leukemia
2007
MLL is fused to CBP, a histone acetyltransferase, in therapy-related acute myeloid leukemia with a t(11;16)(q23;p13.3)
1997
Histone Demethylase KDM5B Collaborates with TFAP2C and Myc To Repress the Cell Cycle Inhibitor p21 cip ( CDKN1A )
2012
The prognostic and functional role of microRNAs in acute myeloid leukemia
2010
LCX, leukemia-associated protein with a CXXC domain, is fused to MLL in acute myeloid leukemia with trilineage dysplasia having t(10;11)(q22;q23).
2002
Cancer Genome Landscapes
2013 StandoutScience
The Importance of Diagnostic Cytogenetics on Outcome in AML: Analysis of 1,612 Patients Entered Into the MRC AML 10 Trial
1998 Standout
Coordinated regulation of transcriptional repression by the RBP2 H3K4 demethylase and Polycomb-Repressive Complex 2
2008
The miR-17-92 microRNA Polycistron Regulates MLL Leukemia Stem Cell Potential by Modulating p21 Expression
2010
The Ubiquitin-Proteasome Proteolytic Pathway: Destruction for the Sake of Construction
2002 StandoutNobel
A decade of genome-wide gene expression profiling in acute myeloid leukemia: flashback and prospects
2008
Coordinated repression of cell cycle genes by KDM5A and E2F4 during differentiation
2012 StandoutNobel
Detection of 14q32 translocations in B-cell malignancies by in situ hybridization with yeast artificial chromosome clones containing the human IgH gene locus
1994
Xenografts of highly resistant leukemia recapitulate the clonal composition of the leukemogenic compartment
2011
Works of Tracy Chaplin being referenced
MicroRNA miR-181a correlates with morphological sub-class of acute myeloid leukaemia and the expression of its target genes in global genome-wide analysis
2007
Genetic lesions in a preleukemic aplasia phase in a child with acute lymphoblastic leukemia
2008
Genome-wide DNA copy number analysis in pancreatic cancer using high-density single nucleotide polymorphism arrays
2007
Histone acetylation-mediated regulation of genes in leukaemic cells
2003
Distinctive Patterns of MicroRNA Expression Associated with Karyotype in Acute Myeloid Leukaemia
2008
Novel regions of acquired uniparental disomy discovered in acute myeloid leukemia
2008
Genome‐wide analysis of acute myeloid leukemia with normal karyotype reveals a unique pattern of homeobox gene expression distinct from those with translocation‐mediated fusion events
2003
Relapsed childhood high hyperdiploid acute lymphoblastic leukemia: presence of preleukemic ancestral clones and the secondary nature of microdeletions and RTK-RAS mutations
2010
Single Nucleotide Polymorphism Array Analysis Defines a Specific Genetic Fingerprint for Well-Differentiated Cutaneous SCCs
2009
Mitotic recombination in haematological malignancy
2009
Functional Analysis of the Transcription Repressor PLU-1/JARID1B
2007
The MLL fusion partner AF10 binds GAS41, a protein that interacts with the human SWI/SNF complex
2002
A novel class of zinc finger/leucine zipper genes identified from the molecular cloning of the t(10;11) translocation in acute leukemia
1995
Molecular analysis of the genomic inversion and insertion ofAF10 intoMLL suggests a single-step event
2001
Establishment of a lymphoblastoid cell line, SD-1, expressing the p190 bcr-abl chimaeric protein.
1991
Cannabis-induced cytotoxicity in leukemic cell lines: the role of the cannabinoid receptors and the MAPK pathway
2004
The leukemia-associated-protein (LAP) domain, a cysteine-rich motif, is present in a wide range of proteins, including MLL, AF10, and MLLT6 proteins.
1995
Chromosome 11q23 translocations in both infant and adult acute leukemias are detected by in situ hybridization with a yeast artificial chromosome
1992
Acquisition of genome-wide copy number alterations in monozygotic twins with acute lymphoblastic leukemia
2010
Genome-Wide Single Nucleotide Polymorphism Analysis Reveals Frequent Partial Uniparental Disomy Due to Somatic Recombination in Acute Myeloid Leukemias
2005
The t(10;11) translocation in acute myeloid leukemia (M5) consistently fuses the leucine zipper motif of AF10 onto the HRX gene
1995
Genomewide Single Nucleotide Polymorphism Microarray Mapping in Basal Cell Carcinomas Unveils Uniparental Disomy as a Key Somatic Event
2005
Combined Array-Comparative Genomic Hybridization and Single-Nucleotide Polymorphism-Loss of Heterozygosity Analysis Reveals Complex Changes and Multiple Forms of Chromosomal Instability in Colorectal Cancers
2006
BCR-ABL and BCR proteins: biochemical characterization and localization.
1990