Standout Papers
Citation Impact
Citing Papers
RIP3, an Energy Metabolism Regulator That Switches TNF-Induced Cell Death from Apoptosis to Necrosis
2009 StandoutScience
Honokiol Induces a Necrotic Cell Death through the Mitochondrial Permeability Transition Pore
2007
Combinations of DNA Methyltransferase and Histone Deacetylase Inhibitors Induce DNA Damage in Small Cell Lung Cancer Cells: Correlation of Resistance with IFN-Stimulated Gene Expression
2010
Id Proteins
2014
Chemopreventive effects of honokiol on UVB-induced skin cancer development.
2010
Characterization of metabolic profile of honokiol in rat feces using liquid chromatography coupled with quadrupole time-of-flight tandem mass spectrometry and 13C stable isotope labeling
2014
Liposomal honokiol, a potent anti-angiogenesis agent, in combination with radiotherapy produces a synergistic antitumor efficacy without increasing toxicity
2008
Honokiol blocks and reverses cardiac hypertrophy in mice by activating mitochondrial Sirt3
2015 Standout
Strategies for subtypes—dealing with the diversity of breast cancer: highlights of the St Gallen International Expert Consensus on the Primary Therapy of Early Breast Cancer 2011
2011 Standout
Improved therapeutic effectiveness by combining liposomal honokiol with cisplatin in lung cancer model
2008
Biological Processes Associated with Breast Cancer Clinical Outcome Depend on the Molecular Subtypes
2008
Hallmarks of Cancer: The Next Generation
2011 Standout
Honokiol induces apoptosis and autophagy via the ROS/ERK1/2 signaling pathway in human osteosarcoma cells in vitro and in vivo
2018 Standout
An integrated encyclopedia of DNA elements in the human genome
2012 StandoutNature
Inhibitory effect of obovatal on the migration and invasion of HT1080 cells via the inhibition of MMP-2
2007
Molecular imaging in drug development
2008 Standout
Honokiol, a small molecular weight natural product, alleviates experimental mesangial proliferative glomerulonephritis
2006
Down-regulation of c-Src/EGFR-mediated signaling activation is involved in the honokiol-induced cell cycle arrest and apoptosis in MDA-MB-231 human breast cancer cells
2009
Preparative purification of anti-tumor derivatives of honokiol by high-speed counter-current chromatography
2007
mTOR Signaling in Growth Control and Disease
2012 Standout
Targeting NF-κB in hematologic malignancies
2006
Plant flavonoids: Classification, distribution, biosynthesis, and antioxidant activity
2022 Standout
Honokiol: a promising small molecular weight natural agent for the growth inhibition of oral squamous cell carcinoma cells
2011
TIGAR, a p53-Inducible Regulator of Glycolysis and Apoptosis
2006 Standout
Oxidative stress, inflammation, and cancer: How are they linked?
2010 Standout
Honokiol causes the p21WAF1‐mediated G(1)‐phase arrest of the cell cycle through inducing p38 mitogen activated protein kinase in vascular smooth muscle cells
2006
Oxidative Stress Hypothesis in Alzheimer's Disease
1997 Standout
Approaches to treat immune hot, altered and cold tumours with combination immunotherapies
2019 Standout
Growth inhibitory effects of obovatol through induction of apoptotic cell death in prostate and colon cancer by blocking of NF-κB
2008
9p21 DNA variants associated with coronary artery disease impair interferon-γ signalling response
2011 Nature
Synthesis and microbiological evaluation of honokiol derivatives as new antimicrobial agents
2010
Therapeutic applications of compounds in the Magnolia family
2011 Standout
Phosphatidic acid signaling to mTOR: Signals for the survival of human cancer cells
2009
Cytotoxic neolignans: an SAR study
2004
Shb Gene Knockdown Increases the Susceptibility of SVR Endothelial Tumor Cells to Apoptotic Stimuli In Vitro and In Vivo
2007
In vitro metabolism and disposition of honokiol in rat and human livers
2011
Tumor Metastasis: Molecular Insights and Evolving Paradigms
2011 Standout
Obovatol inhibits colorectal cancer growth by inhibiting tumor cell proliferation and inducing apoptosis
2008
Atherosclerosis: current pathogenesis and therapeutic options
2011 Standout
Honokiol and magnolol stimulate glucose uptake by activating PI3K‐dependent Akt in L6 myotubes
2012
Honokiol induces cell apoptosis in human chondrosarcoma cells through mitochondrial dysfunction and endoplasmic reticulum stress
2009
Role of Nrf2/HO-1 system in development, oxidative stress response and diseases: an evolutionarily conserved mechanism
2016 Standout
Role of autophagy in cancer
2007 Standout
STAT3 as a central mediator of neoplastic cellular transformation
2006
Honokiol: A potent chemotherapy candidate for human colorectal carcinoma
2004
Necrotic death as a cell fate
2006
Delivery technologies for cancer immunotherapy
2019 Standout
Protective effects of honokiol against oxidized LDL-induced cytotoxicity and adhesion molecule expression in endothelial cells
2006
Honokiol Crosses BBB and BCSFB, and Inhibits Brain Tumor Growth in Rat 9L Intracerebral Gliosarcoma Model and Human U251 Xenograft Glioma Model
2011
The natural product honokiol inhibits calcineurin inhibitor-induced and Ras-mediated tumor promoting pathways
2013
Hepatitis B Virus Promotes Angiopoietin-2 Expression in Liver Tissue
2006
Targeting the IL-6/JAK/STAT3 signalling axis in cancer
2018 Standout
Immunity, Inflammation, and Cancer
2010 Standout
Evaluation of Factors Related to Late Recurrence - Later than 10 Years after the Initial Treatment - in Primary Breast Cancer
2013 Standout
STAT1 Pathway Mediates Amplification of Metastatic Potential and Resistance to Therapy
2009
IFNβ-dependent increases in STAT1, STAT2, and IRF9 mediate resistance to viruses and DNA damage
2013 StandoutNobel
The Pharmacokinetics and Tissue Distribution of Honokiol and its Metabolites in Rats
2015
Enhancement of therapeutic effectiveness by combining liposomal honokiol with cisplatin in ovarian carcinoma
2007
Liposomal honokiol, a promising agent for treatment of cisplatin-resistant human ovarian cancer
2008
STATs in cancer inflammation and immunity: a leading role for STAT3
2009 Standout
Synergistic antitumor effects of liposomal honokiol combined with adriamycin in breast cancer models
2008
Anti-tumor effect of honokiol alone and in combination with other anti-cancer agents in breast cancer
2008
The immune contexture in human tumours: impact on clinical outcome
2012 Standout
Targeting the duality of cancer
2017
Photodynamic therapy of cancer: An update
2011 Standout
Fetal hemoglobin induction by histone deacetylase inhibitors involves generation of reactive oxygen species
2006
Origin and physiological roles of inflammation
2008 StandoutNature
Long noncoding RNAs and human disease
2011 Standout
Honokiol activates AMP-activated protein kinase in breast cancer cells via an LKB1-dependent pathway and inhibits breast carcinogenesis
2012
Honokiol inhibits TNF-α-stimulated NF-κB activation and NF-κB-regulated gene expression through suppression of IKK activation
2005
Progress and challenges in translating the biology of atherosclerosis
2011 StandoutNature
Improved solubility and pharmacokinetics of PEGylated liposomal honokiol and human plasma protein binding ability of honokiol
2011
Honokiol, a natural plant product, inhibits the bone metastatic growth of human prostate cancer cells
2007
Honokiol, a natural therapeutic candidate, induces apoptosis and inhibits angiogenesis of ovarian tumor cells
2008
Repertoires of Autophagy in the Pathogenesis of Ocular Diseases
2015 Standout
Honokiol-mediated Inhibition of PI3K/mTOR Pathway
2009
PGE2-EP2/EP4 signaling elicits immunosuppression by driving the mregDC-Treg axis in inflammatory tumor microenvironment
2022 StandoutNobel
Autophagy promotes tumor cell survival and restricts necrosis, inflammation, and tumorigenesis
2006 Standout
Inhibition of NADPH oxidase-related oxidative stress-triggered signaling by honokiol suppresses high glucose-induced human endothelial cell apoptosis
2008
Honokiol inhibits gastric tumourigenesis by activation of 15‐lipoxygenase‐1 and consequent inhibition of peroxisome proliferator‐activated receptor‐γ and COX‐2‐dependent signals
2010
Honokiol Induces Calpain-Mediated Glucose-Regulated Protein-94 Cleavage and Apoptosis in Human Gastric Cancer Cells and Reduces Tumor Growth
2007
Discovery and resupply of pharmacologically active plant-derived natural products: A review
2015 Standout
Interferons α and β in cancer: therapeutic opportunities from new insights
2019
Identification of Cyclobutane Pyrimidine Dimer-Responsive Genes Using UVB-Irradiated Human Keratinocytes Transfected with In Vitro-Synthesized Photolyase mRNA
2015 StandoutNobel
Targeting cancer cells by ROS-mediated mechanisms: a radical therapeutic approach?
2009 Standout
Honokiol is a potent scavenger of superoxide and peroxyl radicals
2008
Embryo-fetal development toxicity of honokiol microemulsion intravenously administered to pregnant rats
2015
Hepatic Stellate Cells: Protean, Multifunctional, and Enigmatic Cells of the Liver
2008 Standout
Role of the JAK–STAT pathway in myocardial injury
2006
Honokiol: A Novel Natural Agent for Cancer Prevention and Therapy
2012 Standout
Synthesis, cytotoxicity, and antiviral activities of new neolignans related to honokiol and magnolol
2007
US Imaging of Tumor Angiogenesis with Microbubbles Targeted to Vascular Endothelial Growth Factor Receptor Type 2 in Mice
2008
Identification of honokiol metabolites in rats by the method of stable isotope cluster technique and ultra-high performance liquid chromatography/quadrupole-time-of-flight mass spectrometry
2013
Down-regulation of P-glycoprotein expression in MDR breast cancer cell MCF-7/ADR by honokiol
2006
Honokiol, a phytochemical from the Magnolia plant, inhibits photocarcinogenesis by targeting UVB-induced inflammatory mediators and cell cycle regulators: development of topical formulation
2010
Honokiol, a Multifunctional Antiangiogenic and Antitumor Agent
2009 Standout
Apoptosis: A Target for Anticancer Therapy
2018 Standout
Silibinin Inhibits Inflammatory and Angiogenic Attributes in Photocarcinogenesis in SKH-1 Hairless Mice
2007
Regulation and Function of NF-κB Transcription Factors in the Immune System
2009 Standout
DNA Topoisomerase I Inhibitors: Chemistry, Biology, and Interfacial Inhibition
2009 Standout
Honokiol, a Constituent of Oriental Medicinal Herb Magnolia officinalis, Inhibits Growth of PC-3 Xenografts In vivo in Association with Apoptosis Induction
2008
Structural Modification of Honokiol, a Biphenyl Occurring in Magnolia officinalis: the Evaluation of Honokiol Analogues as Inhibitors of Angiogenesis and for Their Cytotoxicity and Structure–Activity Relationship
2011
Signal Transducer and Activator of Transcription 1 Regulates Both Cytotoxic and Prosurvival Functions in Tumor Cells
2007
Safety and Toxicology of Magnolol and Honokiol
2018 Standout
Ruthenium (II) complexes containing a new asymmetric ligand: DNA interaction, photocleavage and topoisomerase I inhibition
2013
Honokiol causes G0-G1 phase cell cycle arrest in human prostate cancer cells in association with suppression of retinoblastoma protein level/phosphorylation and inhibition of E2F1 transcriptional activity
2007
Honokiol Inhibits Epidermal Growth Factor Receptor Signaling and Enhances the Antitumor Effects of Epidermal Growth Factor Receptor Inhibitors
2010
Honokiol, a Natural Plant Product, Inhibits Inflammatory Signals and Alleviates Inflammatory Arthritis
2007 Standout
In Vivo/Ex Vivo and In Situ Assays Used in Cancer Research: A Brief Review
2008
Suppression of Mammary Carcinoma Growth by Retinoic Acid: Proapoptotic Genes Are Targets for Retinoic Acid Receptor and Cellular Retinoic Acid–Binding Protein II Signaling
2005
Inhibition of Tumor Angiogenesis by Interferon-γ by Suppression of Tumor-Associated Macrophage Differentiation
2014
Identification of simple arylfluorosulfates as potent agents against resistant bacteria
2021 StandoutNobel
Targeting Signal Transducer and Activator of Transcription Signaling Pathway in Leukemias
2009
Honokiol: A Review of Its Anticancer Potential and Mechanisms
2019
Current Perspectives of the Applications of Polyphenols and Flavonoids in Cancer Therapy
2020
Honokiol, a natural biphenyl, inhibits in vitro and in vivo growth of breast cancer through induction of apoptosis and cell cycle arrest
2007
Oxidative stress and cancer: have we moved forward?
2006
Arylfluorosulfates Inactivate Intracellular Lipid Binding Protein(s) through Chemoselective SuFEx Reaction with a Binding Site Tyr Residue
2016 StandoutNobel
Identification of a Naturally Occurring Rexinoid, Honokiol, That Activates the Retinoid X Receptor
2010
Facile Purification of Honokiol and Its Antiviral and Cytotoxic Properties
2006
Honokiol overcomes conventional drug resistance in human multiple myeloma by induction of caspase-dependent and -independent apoptosis
2005
Comparative Study of Antioxidant Properties and Total Phenolic Content of 30 Plant Extracts of Industrial Interest Using DPPH, ABTS, FRAP, SOD, and ORAC Assays
2009 Standout
Heterocyclic Nanographenes and Other Polycyclic Heteroaromatic Compounds: Synthetic Routes, Properties, and Applications
2016 Standout
Honokiol Potentiates Apoptosis, Suppresses Osteoclastogenesis, and Inhibits Invasion through Modulation of Nuclear Factor-κB Activation Pathway
2006
Hydrogen Sulfide Mediates Cardioprotection Through Nrf2 Signaling
2009 Standout
Honokiol Suppresses Survival Signals Mediated by Ras-Dependent Phospholipase D Activity in Human Cancer Cells
2008
Honokiol, a phytochemical from Magnolia spp., inhibits breast cancer cell migration by targeting nitric oxide and cyclooxygenase-2
2011
Works of Traci E. Battle being referenced
Carbazole Is a Naturally Occurring Inhibitor of Angiogenesis and Inflammation Isolated from Antipsoriatic Coal Tar
2006
Honokiol, a Small Molecular Weight Natural Product, Inhibits Angiogenesis in Vitro and Tumor Growth in Vivo
2003 Standout
Retinoic acid-induced blr1 expression requires RARα, RXR, and MAPK activation and uses ERK2 but not JNK/SAPK to accelerate cell differentiation
2001
Oral fludarabine has significant activity in patients with previously untreated chronic lymphocytic leukemia, and leads to increased STAT1 levels in vivo
2003
STAT1 mediates differentiation of chronic lymphocytic leukemia cells in response to Bryostatin 1
2003
The natural product honokiol induces caspase-dependent apoptosis in B-cell chronic lymphocytic leukemia (B-CLL) cells
2005 Standout
Honokiol, a Small Molecular Weight Natural Product, Inhibits Angiogenesis in Vitro and Tumor Growth in Vivo
2021
Reactive oxygen signaling and MAPK activation distinguish Epstein–Barr Virus (EBV)-positive versus EBV-negative Burkitt's lymphoma
2004
Bone marrow and tumor cell colony-forming units and human tumor xenograft efficacy of noncamptothecin and camptothecin topoisomerase I inhibitors
2008
A Small-Molecule Enhancer of Signal Transducer and Activator of Transcription 1 Transcriptional Activity Accentuates the Antiproliferative Effects of IFN-γ in Human Cancer Cells
2007
Signal Transducer and Activator of Transcription 1 Activation in Endothelial Cells Is a Negative Regulator of Angiogenesis
2006