Citation Impact
Citing Papers
Programmable RNA recognition using a CRISPR-associated Argonaute
2018 StandoutNobel
Pathophysiology of Migraine: A Disorder of Sensory Processing
2017 Standout
Adenosine Deaminases Acting on RNA, RNA Editing, and Interferon Action
2010
Multi-target strategies for the improved treatment of depressive states: Conceptual foundations and neuronal substrates, drug discovery and therapeutic application
2006
“Selective” serotonin 5-HT2A receptor antagonists
2022
International Union of Pharmacology nomenclature of adrenoceptors.
1994 StandoutNobel
Adrenergic α2C-Receptors Modulate the Acoustic Startle Reflex, Prepulse Inhibition, and Aggression in Mice
1998 StandoutNobel
Functional Neuroimaging of Anxiety: A Meta-Analysis of Emotional Processing in PTSD, Social Anxiety Disorder, and Specific Phobia
2007 Standout
A Neurotrophic Model for Stress-Related Mood Disorders
2006 Standout
Protein synthesis and the mechanisms of lasting change in anxiety induced by severe stress
2005
Merkel Cells Activate Sensory Neural Pathways through Adrenergic Synapses
2018 StandoutNobel
Contribution of 5-HT2Receptor Subtypes to Sleep–Wakefulness and Respiratory Control, and Functional Adaptations in Knock-Out Mice Lacking 5-HT2AReceptors
2005
Adrenergic and Imidazoline Receptor‐Mediated Responses to UK‐14,304‐18 (Brimonidine) in Rabbits and Monkeys
1995
5-HT2C receptors mediate penile erections in rats: actions of novel and selective agonists and antagonists
1997
5-HT2 receptors modulate excitatory neurotransmission to cardiac vagal neurons within the nucleus ambiguus evoked during and after hypoxia
2009 StandoutNobel
Synthesis and binding affinity of new pyrazole and isoxazole derivatives as potential atypical antipsychotics
2007
Molecular, pharmacological and functional diversity of 5-HT receptors
2002 Standout
Allosteric modulation of 5-HT3 receptors: focus on alcohols and anaesthetic agents
1996
Descending control of pain
2002 Standout
Prolonged Kappa Opioid Receptor Phosphorylation Mediated by G-protein Receptor Kinase Underlies Sustained Analgesic Tolerance
2004 StandoutNobel
Pharmacology of antidepressants
2001
Activation of 5-HT 2B Receptors in the Medial Amygdala causes Anxiolysis in the Social Interaction Test in the Rat
1997
The modified Geller–Seifter test in rats was insensitive to GABAB receptor positive modulation or blockade, or 5-HT1A receptor activation
2009
Mechanical, thermal and formalin-induced nociception is differentially altered in 5-HT1A−/−, 5-HT1B−/−, 5-HT2A−/−, 5-HT3A−/− and 5-HTT−/− knock-out male mice
2007 StandoutNobel
Hyponatremia in cirrhosis: From pathogenesis to treatment†
1998
Network pharmacology: the next paradigm in drug discovery
2008 Standout
The use of the elevated plus maze as an assay of anxiety-related behavior in rodents
2007 Standout
Locomotor networks are targets of modulation by sensory transient receptor potential vanilloid 1 and transient receptor potential melastatin 8 channels
2009 StandoutNobel
Effects of the Serotonin Type 2A, 3A and 3B Receptor and the Serotonin Transporter Genes on Paroxetine and Fluvoxamine Efficacy and Adverse Drug Reactions in Depressed Japanese Patients
2006
Agonist-directed trafficking of signalling at serotonin 5-HT2A, 5-HT2B and 5-HT2C-VSV receptors mediated Gq/11 activation and calcium mobilisation in CHO cells
2008
The Pharmacological and Functional Characteristics of the Serotonin 5-HT3A Receptor Are Specifically Modified by a 5-HT3B Receptor Subunit
1999
Evidence that hypophagia induced by d-fenfluramine and d-norfenfluramine in the rat is mediated by 5-HT2C receptors
2001
Interaction of Serotonin 5-Hydroxytryptamine Type 2C Receptors with PDZ10 of the Multi-PDZ Domain Protein MUPP1
2001
The Serotonin Signaling System: From Basic Understanding To Drug Development for Functional GI Disorders
2007 Standout
Indigenous Bacteria from the Gut Microbiota Regulate Host Serotonin Biosynthesis
2015 Standout
Distribution of the 5-hydroxytryptamine2C receptor protein in adult rat brain and spinal cord determined using a receptor-directed antibody: Effect of 5,7-dihydroxytryptamine
1997
A short history of the 5-HT2C receptor: from the choroid plexus to depression, obesity and addiction treatment
2017
Molecular Mechanisms of Depression: Perspectives on New Treatment Strategies
2013 Standout
Differential actions of typical and atypical antipsychotic drugs on dopamine release in the core and shell of the nucleus accumbens
1996
Therapeutic potential of β-arrestin- and G protein-biased agonists
2010 StandoutNobel
SB 242084, a Selective and Brain Penetrant 5-HT 2C Receptor Antagonist
1997
Serotonin receptors and their role in the pathophysiology and therapy of irritable bowel syndrome
2014
Gene targeting — homing in on α2-adrenoceptor-subtype function
1997 StandoutNobel
Novelty and Anxiolytic Drugs Dissociate Two Components of Hippocampal Theta in Behaving Rats
2013 StandoutNobel
Antinociceptive effect of peripheral serotonin 5-HT2B receptor activation on neuropathic pain
2012
To translate, or not to translate: viral and host mRNA regulation by interferon-stimulated genes
2015 StandoutNobel
Serotonin2C receptors tonically suppress the activity of mesocortical dopaminergic and adrenergic, but not serotonergic, pathways: A combined dialysis and electrophysiological analysis in the rat
2000
Disruption of the kappa -opioid receptor gene in mice enhances sensitivity to chemical visceral pain, impairs pharmacological actions of the selective kappa -agonist U-50,488H and attenuates morphine withdrawal
1998
Two functionally distinct α2-adrenergic receptors regulate sympathetic neurotransmission
1999 StandoutNatureNobel
A-to-I RNA Editing and Human Disease
2006
Enhancement of antipsychotic-like properties of the dopamine D2 receptor antagonist, raclopride, by the additional treatment with the 5-HT2 receptor blocking agent, ritanserin, in the rat
1996
The elevated T-maze as an experimental model of anxiety
1998
Autoradiographic localization of dopamine D1 and D2 receptors in rat nucleus accumbens: Resistance to differential rearing conditions
1991 Standout
G Protein-coupled Receptor Kinase 5 Regulates β1-Adrenergic Receptor Association with PSD-95
2002 StandoutNobel
Pharmacologic and Therapeutic Applications of alpha2-Adrenoceptor Subtypes
1993
Relationship Between Dopamine D2 Occupancy, Clinical Response, and Side Effects: A Double-Blind PET Study of First-Episode Schizophrenia
2000 Standout
Neurobiology of Depression
2002 Standout
5‐HT 2C receptor modulation and the treatment of obesity
1999
RS‐127445: a selective, high affinity, orally bioavailable 5‐HT2B receptor antagonist
1999
Comparative efficacy and acceptability of 12 new-generation antidepressants: a multiple-treatments meta-analysis
2009 Standout
A review of central 5-HT receptors and their function
1999 Standout
Major Depressive Disorder
2008 Standout
The neural basis of psychedelic action
2022 Standout
Genetic alteration of the α2-adrenoceptor subtype c in mice affects the development of behavioral despair and stress-induced increases in plasma corticosterone levels
1999 StandoutNobel
Differential Distribution of β-Adrenergic Receptor Subtypes in Blood Vessels of Knockout Mice Lacking β1-or β2-Adrenergic Receptors
2001 StandoutNobel
RS-102221: A Novel High Affinity and Selective, 5-HT 2C Receptor Antagonist
1997
The 5-HT3B subunit is a major determinant of serotonin-receptor function
1999 Nature
Characterization of SB‐271046: A potent, selective and orally active 5‐HT6 receptor antagonist
2000
Modified 5-HT3A receptor function by co-expression of alternatively spliced human 5-HT3A receptor isoforms
2000
Pharmacological characterisation of human 5-HT2 receptor subtypes
2001
The Novel Melatonin Agonist Agomelatine (S20098) Is an Antagonist at 5-Hydroxytryptamine2C Receptors, Blockade of Which Enhances the Activity of Frontocortical Dopaminergic and Adrenergic Pathways
2003
Endocannabinoid-Mediated Control of Synaptic Transmission
2009
AGA technical review on irritable bowel syndrome
2002 Standout
Discriminative stimulus properties of the novel serotonin (5-HT)2C receptor agonist, RO60-0175: a pharmacological analysis
1999
In vitroandin vivoprofile of SB 206553, a potent 5‐HT2C/5‐HT2Breceptor antagonist with anxiolytic‐like properties
1996
Anxiolytic properties of agomelatine, an antidepressant with melatoninergic and serotonergic properties: role of 5-HT2C receptor blockade
2004
Trends in the Development of New Antidepressants. Is there a Light at the End of the Tunnel?
2004
Regional distribution and cellular localization of 5‐HT2C receptor mRNA in monkey brain: Comparison with [3H]mesulergine binding sites and choline acetyltransferase mRNA
2001
5‐HT3‐receptor subunits A and B are co‐expressed in neurons of the dorsal root ganglion
2001
Vascular α-adrenoceptors: from the gene to the human
1995
Uropathic Observations in Mice Expressing a Constitutively Active Point Mutation in the 5-HT3AReceptor Subunit
2004 StandoutNobel
Genetic Alteration of α2C-Adrenoceptor Expression in Mice: Influence on Locomotor, Hypothermic, and Neurochemical Effects of Dexmedetomidine, a Subtype-Nonselective α2-Adrenoceptor Agonist
1997 StandoutNobel
Differential Composition of 5-Hydroxytryptamine3Receptors Synthesized in the Rat CNS and Peripheral Nervous System
2002
Unresponsiveness to Cannabinoids and Reduced Addictive Effects of Opiates in CB 1 Receptor Knockout Mice
1999 StandoutScience
The 5-HT3Subtype of Serotonin Receptor Contributes to Nociceptive Processing via a Novel Subset of Myelinated and Unmyelinated Nociceptors
2002 StandoutNobel
Marine Indole Alkaloids: Potential New Drug Leads for the Control of Depression and Anxiety
2010 Standout
MOD-1 is a serotonin-gated chloride channel that modulates locomotory behaviour in C. elegans
2000 StandoutNatureNobel
Effects of centrally administered anxiolytic compounds in animal models of anxiety
1999
Stressor Controllability, Anxiety, and Serotonin
1998
Cardiovascular Regulation in Mice Lacking α 2 -Adrenergic Receptor Subtypes b and c
1996 StandoutScienceNobel
Reciprocal autoreceptor and heteroreceptor control of serotonergic, dopaminergic and noradrenergic transmission in the frontal cortex: relevance to the actions of antidepressant agents
2000
Regulation of G Protein–Coupled Receptor Signaling by Scaffold Proteins
2002 StandoutNobel
Antinociceptive Action of Nitrous Oxide Is Mediated by Stimulation of Noradrenergic Neurons in the Brainstem and Activation of α2BAdrenoceptors
2000 StandoutNobel
Head‐twitch response in rodents induced by the hallucinogen 2,5‐dimethoxy‐4‐iodoamphetamine: a comprehensive history, a re‐evaluation of mechanisms, and its utility as a model
2012
Serotonin Receptors
2008
Rab3B protein is required for long-term depression of hippocampal inhibitory synapses and for normal reversal learning
2011 StandoutNobel
Cellular and subcellular distribution of the serotonin 5-HT2A receptor in the central nervous system of adult rat
1999
From 2000 to Mid-2010: A Fruitful Decade for the Synthesis of Pyrazoles
2011 Standout
5-HT2AReceptor-Mediated Regulation of Brain-Derived Neurotrophic Factor mRNA in the Hippocampus and the Neocortex
1997
INSIGHTS FROM IN VIVO MODIFICATION OF ADRENERGIC RECEPTOR GENE EXPRESSION
1998 StandoutNobel
Aquaporins in the Kidney: From Molecules to Medicine
2002 StandoutNobel
5-HT2C Receptor Agonists: Pharmacological Characteristics and Therapeutic Potential
1998
Gene targeting — homing in on α2-adrenoceptor-subtype function
1997 StandoutNobel
Physiology of Microglia
2011 Standout
Works of T.P. Blackburn being referenced
Cloning and functional expression of a human 5-hydroxytryptamine type 3AS receptor subunit.
1995
Attenuation of haloperidol‐induced catalepsy by a 5‐HT2C receptor antagonist
1999
SB-243213; a selective 5-HT2C receptor inverse agonist with improved anxiolytic profile: lack of tolerance and withdrawal anxiety
2001
Studies on the role of 5-HT2C and 5-HT2B receptors in regulating generalised seizure threshold in rodents
1998
Profile of SB‐204269, a mechanistically novel anticonvulsant drug, in rat models of focal and generalized epileptic seizures
1997
Evidence for expression of the 5-hydroxytryptamine-2B receptor protein in the rat central nervous system
1997
BW 723C86, a 5-HT2B Receptor Agonist, Causes Hyperphagia and Reduced Grooming in Rats
1997
5-HT2 receptor subtypes: A family re-united?
1995
Effects of the 5‐HT2B receptor agonist, BW 723C86, on three rat models of anxiety
1996
On the mechanisms of k‐opioid‐induced diuresis
1986
Additional evidence for functional subclassification of alpha-2 adrenoceptors based on a new selective antagonist, SK&F 104856.
1991
κ‐Opioid‐induced changes in renal water and electrolyte management and endocrine secretion
1989