Citation Impact
Citing Papers
A Sulfilimine Bond Identified in Collagen IV
2009 StandoutScienceNobel
Identification and proteomic profiling of exosomes in human urine
2004 Standout
Programmed Death 1 Ligand (PD-L) 1 and PD-L2 Limit Autoimmune Kidney Disease: Distinct Roles
2007
Identification of the Interaction Site within Acyl-CoA:Cholesterol Acyltransferase 2 for the Isoform-specific Inhibitor Pyripyropene A
2008 StandoutNobel
RAGE Drives the Development of Glomerulosclerosis and Implicates Podocyte Activation in the Pathogenesis of Diabetic Nephropathy
2003
Elevated expression of transforming growth factor-beta and proteoglycan production in experimental glomerulonephritis. Possible role in expansion of the mesangial extracellular matrix.
1990
Lipoprotein and cholesterol metabolism in diet-induced coronary artery atherosclerosis in primates.
1998
Acromegaly
2006 Standout
Fibrosis in Systemic Sclerosis
2008
A Molecular Profile of Focal Segmental Glomerulosclerosis from Formalin-Fixed, Paraffin-Embedded Tissue
2010
Type IV collagens regulate BMP signalling in Drosophila
2008 Nature
Inflammation and metabolic disorders
2006 StandoutNature
Urinary Proteomics and Biomarker Discovery for Glomerular Diseases
2003
Advanced glycation end products inhibit de novo protein synthesis and induce TGF-β overexpression in proximal tubular cells
2003
TGF-β: Regulation of extracellular matrix
1992
Regulation of Connective Tissue Growth Factor Activity in Cultured Rat Mesangial Cells and Its Expression in Experimental Diabetic Glomerulosclerosis
2000
Epithelial-Mesenchymal Transitions in Development and Disease
2009 Standout
The biology of RAGE and its ligands: Uncovering mechanisms at the heart of diabetes and its complications
2007
CD22 blockade restores homeostatic microglial phagocytosis in ageing brains
2019 StandoutNatureNobel
Molecular mechanisms of epithelial–mesenchymal transition
2014 Standout
Cell Signaling by Receptor Tyrosine Kinases
2010 Standout
Changes in the Expression of Nephrin Gene and Protein in Experimental Diabetic Nephropathy
2001
Podocytic PKC-Alpha Is Regulated in Murine and Human Diabetes and Mediates Nephrin Endocytosis
2010
Renoprotective Effect of the Angiotensin-Receptor Antagonist Irbesartan in Patients with Nephropathy Due to Type 2 Diabetes
2001 Standout
Prevention of diabetic nephropathy in mice by a diet low in glycoxidation products
2002
Ribozyme Targeting of Receptor for Advanced Glycation End Products in Mouse Mesangial Cells
1998
Receptor for AGEs (RAGE) blockade may exert its renoprotective effects in patients with diabetic nephropathy via induction of the angiotensin II type 2 (AT2) receptor
2010
Hallmarks of aging: An expanding universe
2023 Standout
Mouse Models of Diabetic Nephropathy
2004
Glomerulosclerosis induced by in vivo transfection of transforming growth factor-beta or platelet-derived growth factor gene into the rat kidney.
1993
Renal Gene and Protein Expression Signatures for Prediction of Kidney Disease Progression
2009
Catalytic Asymmetric Conjugate Addition/Oxidative Dearomatization Towards Multifunctional Spirocyclic Compounds
2011 StandoutNobel
Synthesis and secretion of hepatic apolipoprotein B-containing lipoproteins
1994
Advanced Glycation End Product-induced Apoptosis and Overexpression of Vascular Endothelial Growth Factor and Monocyte Chemoattractant Protein-1 in Human-cultured Mesangial Cells
2002
Phagocytosis of apoptotic cells in homeostasis
2015
Oncogenic pathway signatures in human cancers as a guide to targeted therapies
2005 StandoutNature
Stimulation of collagen gene expression and protein synthesis in murine mesangial cells by high glucose is mediated by autocrine activation of transforming growth factor-beta.
1994
Regulation of Marginal Zone B Cell Development by MINT, a Suppressor of Notch/RBP-J Signaling Pathway
2003 StandoutNobel
Autocrine secretion of transforming growth factor-β in cultured rat mesangial cells
1992
Scleroderma
2009 Standout
Paricalcitol Attenuates Renal Interstitial Fibrosis in Obstructive Nephropathy
2006
Mutation of the mouse klotho gene leads to a syndrome resembling ageing
1997 StandoutNature
The NOX Family of ROS-Generating NADPH Oxidases: Physiology and Pathophysiology
2007 Standout
Immunological Quantitation and Localization of ACAT-1 and ACAT-2 in Human Liver and Small Intestine
2000
Angiotensin II stimulates extracellular matrix protein synthesis through induction of transforming growth factor-beta expression in rat glomerular mesangial cells.
1994 Standout
Suppression of experimental glomerulonephritis by antiserum against transforming growth factor β1
1990 Nature
Hypoxia and the extracellular matrix: drivers of tumour metastasis
2014 StandoutNobel
Piezos thrive under pressure: mechanically activated ion channels in health and disease
2017 StandoutNobel
Adverse Renal Effects of Immune Checkpoint Inhibitors: A Narrative Review
2017 Standout
Somatic misexpression of germline P granules and enhanced RNA interference in retinoblastoma pathway mutants
2005 StandoutNatureNobel
Structural basis for Gas6–Axl signalling
2005
Endoplasmic Reticulum Stress and the Inflammatory Basis of Metabolic Disease
2010 Standout
A New Perspective on Therapeutic Inhibition of Advanced Glycation in Diabetic Microvascular Complications: Common Downstream Endpoints Achieved Through Disparate Therapeutic Approaches?
2009
The microenvironment of the tumour–host interface
2001 StandoutNature
Chronic kidney disease and cardiovascular risk: epidemiology, mechanisms, and prevention
2013 Standout
3 ACAT Inhibitors: The Search for a Novel and Effective Treatment of Hypercholesterolemia and Atherosclerosis
2002
Enhanced production of glomerular extracellular matrix in a new mouse strain of high serum IgA ddY mice
1996
Stomatin-domain proteins
2011
M-Type Phospholipase A 2 Receptor as Target Antigen in Idiopathic Membranous Nephropathy
2009 Standout
In situ class switching and differentiation to IgA-producing cells in the gut lamina propria
2001 StandoutNatureNobel
Experimental membranous nephropathy redux
2005
Mice carrying a knock-in mutation of Aicda resulting in a defect in somatic hypermutation have impaired gut homeostasis and compromised mucosal defense
2011 StandoutNobel
The pathobiology of the mesangium
1992
Origin and physiological roles of inflammation
2008 StandoutNature
Senescence‐Accelerated Mouse (SAM): A Novel Murine Model of Accelerated Senescence
1991
Biochemistry and molecular cell biology of diabetic complications
2001 StandoutNature
Reduced Incidence and Delayed Occurrence of Fatal Neoplastic Diseases in Growth Hormone Receptor/Binding Protein Knockout Mice
2009
Transforming Growth Factor β in Tissue Fibrosis
1994 Standout
Intestinal IgA synthesis: regulation of front-line body defences
2003 StandoutNobel
Transforming growth factor-β regulates production of proteoglycans by mesangial cells
1990
mTORC1 activation in podocytes is a critical step in the development of diabetic nephropathy in mice
2011
CCR2 antagonism improves insulin resistance, lipid metabolism, and diabetic nephropathy in type 2 diabetic mice
2010
A coding-independent function of gene and pseudogene mRNAs regulates tumour biology
2010 StandoutNature
Reduced angiotensinogen expression attenuates renal interstitial fibrosis in obstructive nephropathy in mice
1999 StandoutNobel
Candidate rejuvenating factor GDF11 and tissue fibrosis: friend or foe?
2020
Mouse Models of Diabetic Nephropathy
2009 Nobel
Stimulation of adipogenesis in fibroblasts by PPARγ2, a lipid-activated transcription factor
1994 Standout
HMGB1, TLR and RAGE: a functional tripod that leads to diabetic inflammation
2011
High glucose-induced proliferation in mesangial cells is reversed by autocrine TGF-β
1992
Differential effects of diabetes on the expression of the gp91phox homologues nox1 and nox4
2005
Vitamin D Therapy in Chronic Kidney Disease and End Stage Renal Disease
2011
Intraglomerular pressure and mesangial stretching stimulate extracellular matrix formation in the rat.
1992
TGF-β activates Akt kinase through a microRNA-dependent amplifying circuit targeting PTEN
2009
Hormonal regulation of longevity in mammals
2007
Receptor for Advanced Glycation End Products (RAGE) Deficiency Attenuates the Development of Atherosclerosis in Diabetes
2008
Relation Between Development of Nephropathy and the p22phox C242T and Receptor for Advanced Glycation End Product G1704T Gene Polymorphisms in Type 2 Diabetic Patients
2004
Growth Hormone Receptor Antagonists: Discovery, Development, and Use in Patients with Acromegaly
2002
Long-Term Renal Effects of a Neutralizing RAGE Antibody in Obese Type 2 Diabetic Mice
2004
Mice carrying null mutations of the genes encoding insulin-like growth factor I (Igf-1) and type 1 IGF receptor (Igf1r)
1993 Standout
Advanced glycation end products activate Smad signaling via TGF‐β‐dependent and ‐independent mechanisms: implications for diabetic renal and vascular disease
2003
Temporal expression of autocrine growth factors corresponds to morphological features of mesangial proliferation in Habu snake venom-induced glomerulonephritis.
1993
Apolipoprotein B mRNA-editing protein induces hepatocellular carcinoma and dysplasia in transgenic animals.
1995 StandoutNobel
Diabetic nephropathy is markedly enhanced in mice lacking the bradykinin B2 receptor
2004 StandoutNobel
Epithelial-to-mesenchymal transition induces cell cycle arrest and parenchymal damage in renal fibrosis
2015 StandoutNobel
Spermatogenesis following male germ-cell transplantation.
1994 Standout
Novel splice variants of the receptor for advanced glycation end-products expressed in human vascular endothelial cells and pericytes, and their putative roles in diabetes-induced vascular injury
2003
Aberrant expansion of segmented filamentous bacteria in IgA-deficient gut
2004 StandoutNobel
The Endoplasmic Reticulum Chaperone Improves Insulin Resistance in Type 2 Diabetes
2005
Migration and Differentiation of Autoreactive B-1 Cells Induced by Activated γ/δ T Cells in Antierythrocyte Immunoglobulin Transgenic Mice
2000 StandoutNobel
From Hyperglycemia to Diabetic Kidney Disease: The Role of Metabolic, Hemodynamic, Intracellular Factors and Growth Factors/Cytokines
2004
ACAT2 Is Localized to Hepatocytes and Is the Major Cholesterol-Esterifying Enzyme in Human Liver
2004 StandoutNobel
Distinct gene expression phenotypes of cells lacking Rb and Rb family members.
2003
TGF-β signal transduction and mesangial cell fibrogenesis
2003
Regulation of insulin-like growth factor I receptors in diabetic mesangial cells
1991
Receptor-specific increase in extracellular matrix production in mouse mesangial cells by advanced glycosylation end products is mediated via platelet-derived growth factor.
1992
T-Independent Immune Response: New Aspects of B Cell Biology
2000 StandoutScienceNobel
Increased Frequency of Surface IgA-Positive Plasma Cells in the Intestinal Lamina Propria and Decreased IgA Excretion in Hyper IgA (HIGA) Mice, a Murine Model of IgA Nephropathy with Hyperserum IgA
2000 StandoutNobel
Mechanisms of Diabetic Complications
2013 Standout
High glucose level unmasks a genetic predisposition to enhanced extracellular matrix production in mesangial cells from the Milan normotensive strain.
1997
A series of conformationally and sterically constrained analogs of N-phenyl-N′-aralkylurea ACAT inhibitors
1995
Disparate effects on renal and oxidative parameters following RAGE deletion, AGE accumulation inhibition, or dietary AGE control in experimental diabetic nephropathy
2009
Metabolic effects of developmental, tissue-, and cell-specific expression of a chimeric phosphoenolpyruvate carboxykinase (GTP)/bovine growth hormone gene in transgenic mice.
1990
MicroRNA‐377 is up‐regulated and can lead to increased fibronectin production in diabetic nephropathy
2008
mTOR Pathway as a Target in Tissue Hypertrophy
2006
Normal development is an integral part of tumorigenesis in T cell-specific PTEN-deficient mice
2008 StandoutNobel
Chemical Chaperones Reduce ER Stress and Restore Glucose Homeostasis in a Mouse Model of Type 2 Diabetes
2006 StandoutScience
Prevention of Incipient Diabetic Nephropathy by High-Dose Thiamine and Benfotiamine
2003
Transforming growth factor-beta production in anti-glomerular basement membrane disease in the rabbit.
1991
Extending Healthy Life Span—From Yeast to Humans
2010 StandoutScience
Human and rat mesangial cell receptors for glucose-modified proteins: potential role in kidney tissue remodelling and diabetic nephropathy.
1991
Reduced growth, abnormal kidney structure, and type 2 (AT 2 ) angiotensin receptor-mediated blood pressure regulation in mice lacking both AT 1A and AT 1B receptors for angiotensin II
1998 StandoutNobel
A novel somatostatin analogue prevents early renal complications in the nonobese diabetic mouse
2001
Genetic Engineering of Livestock
1989 Science
Works of Toshio Doi being referenced
A Vitamin D Analog Ameliorates Glomerular Injury on Rat Glomerulonephritis
2001
Activation of Bone Morphogenetic Protein 4 Signaling Leads to Glomerulosclerosis That Mimics Diabetic Nephropathy
2011
Essential role of Gas6 for glomerular injury in nephrotoxic nephritis
2002
Inhibition of MCP-1/CCR2 pathway ameliorates the development of diabetic nephropathy
2007
Gas6 induces Akt/mTOR-mediated mesangial hypertrophy in diabetic nephropathy
2005
SRY-Related HMG Box 9 Regulates the Expression of Col4a2 through Transactivating Its Enhancer Element in Mesangial Cells
2007
Development and prevention of advanced diabetic nephropathy in RAGE-overexpressing mice
2001
Expression of Smad1 is directly associated with mesangial matrix expansion in rat diabetic nephropathy
2006
Transforming growth factor-beta. Murine glomerular receptors and responses of isolated glomerular cells.
1989
Roles of the AGE‐RAGE System in Vascular Injury in Diabetesa
2000
Activation of STAT3/Smad1 Is a Key Signaling Pathway for Progression to Glomerulosclerosis in Experimental Glomerulonephritis
2005
Phosphorylation of Nephrin Triggers Its Internalization by Raft-Mediated Endocytosis
2009
Study on PDGF Receptor β Pathway in Glomerular Formation in Neonate Mice
2001
Podocin Participates in the Assembly of Tight Junctions between Foot Processes in Nephrotic Podocytes
2007
Retroviral gp70 antigen in spontaneous mesangial glomerulonephritis of ddY mice
1989
Type IV Collagen Is Transcriptionally Regulated by Smad1 under Advanced Glycation End Product (AGE) Stimulation
2004
Glomerulosclerosis in mice transgenic for growth hormone. Increased mesangial extracellular matrix is correlated with kidney mRNA levels.
1991
Demonstration of C3d Deposits in Membranous Nephropathy
1984
Essential role of Gas6 for glomerular injury in nephrotoxic nephritis
2002
RAGE Control of Diabetic Nephropathy in a Mouse Model
2006
Development and prevention of advanced diabetic nephropathy in RAGE-overexpressing mice
2001
Autoimmune abnormalities in a murine model of accelerated senescence.
1989
Glomerular lesions in nonobese diabetic mouse: before and after the onset of hyperglycemia.
1990
Regulation of apolipoprotein B production and secretion in response to the change of intracellular cholesteryl ester contents in rabbit hepatocytes
1993
Progressive glomerulosclerosis develops in transgenic mice chronically expressing growth hormone and growth hormone releasing factor but not in those expressing insulinlike growth factor-1.
1988