Citation Impact
Citing Papers
Prospective identification of tumorigenic breast cancer cells
2003 Standout
Stress-Dependent Regulation of FOXO Transcription Factors by the SIRT1 Deacetylase
2004 StandoutScience
PARP inhibitors: Synthetic lethality in the clinic
2017 StandoutScience
Hallmarks of Cancer: The Next Generation
2011 Standout
Chaetocin-induced ROS-mediated apoptosis involves ATM–YAP1 axis and JNK-dependent inhibition of glucose metabolism
2014
Innate Immunity in Pluripotent Human Cells
2013
The DNA-damage response in human biology and disease
2009 StandoutNature
BRCA2 Is Required for Homology-Directed Repair of Chromosomal Breaks
2001
Mitotic Checkpoint Inactivation Fosters Transformation in Cells Lacking the Breast Cancer Susceptibility Gene, Brca2
1999 StandoutNobel
AIM2 recognizes cytosolic dsDNA and forms a caspase-1-activating inflammasome with ASC
2009 StandoutNature
Cell cycle proteins as promising targets in cancer therapy
2017 Standout
The DNA damage response pathways: at the crossroad of protein modifications
2007
Cell-cycle checkpoints and cancer
2004 StandoutNature
Regulation of DNA repair in hypoxic cancer cells
2007
RNA Polymerase II Blockage by Cisplatin-damaged DNA
2005
Distinct functional domains of Nbs1 modulate the timing and magnitude of ATM activation after low doses of ionizing radiation
2004
A microRNA component of the p53 tumour suppressor network
2007 StandoutNature
BRAFE600-associated senescence-like cell cycle arrest of human naevi
2005 StandoutNature
Targeting the DNA repair defect in BRCA mutant cells as a therapeutic strategy
2005 StandoutNature
Signal transduction by the c-Jun N-terminal kinase (JNK) — from inflammation to development
1998
p21/CDKN1A Mediates Negative Regulation of Transcription by p53
2003
The Breast Cancer Susceptibility Gene BRCA1 Is Required for Subnuclear Assembly of Rad51 and Survival following Treatment with the DNA Cross-linking Agent Cisplatin
2000
Human SIR2 deacetylates p53 and antagonizes PML/p53-induced cellular senescence
2002
The HIN domain of IFI-200 proteins consists of two OB folds
2004
Identification and functional analysis of TopBP1 and its homologs
2005
IFI16 Acts as a Nuclear Pathogen Sensor to Induce the Inflammasome in Response to Kaposi Sarcoma-Associated Herpesvirus Infection
2011
Biochemical and growth regulatory activities of the HIN-200 family member and putative tumor suppressor protein, AIM2
2004
Fibronectin, integrins, and growth control
2001
Ubiquitin-dependent regulation of COPII coat size and function
2012 StandoutNatureNobel
Conditional mutation of Brca1 in mammary epithelial cells results in blunted ductal morphogenesis and tumour formation
1999
Rap1 mediates sustained MAP kinase activation induced by nerve growth factor
1998 Nature
The DNA Damage Response: Making It Safe to Play with Knives
2010 Standout
BRCA1 and its toolbox for the maintenance of genome integrity
2009
Phosphorylation of c-Crk II on the Negative Regulatory Tyr222 Mediates Nerve Growth Factor-induced Cell Spreading and Morphogenesis
2000
Intrinsic Immunity Shapes Viral Resistance of Stem Cells
2017 StandoutNobel
The Microprocessor complex mediates the genesis of microRNAs
2004 StandoutNature
Epithelial cancer in Fanconi anemia complementation group D2 (Fancd2) knockout mice
2003
BRCA1 protein is linked to the RNA polymerase II holoenzyme complex via RNA helicase A
1998
Identification of specific autoantigens in Sjögren's syndrome by SEREX
2005
Costimulation through CD28 Suppresses T Cell Receptor-dependent Activation of the Ras-like Small GTPase Rap1 in Human T Lymphocytes
1998
Genome maintenance mechanisms for preventing cancer
2001 StandoutNature
Mutation in Brca2 stimulates error-prone homology-directed repair of DNA double-strand breaks occurring between repeated sequences
2001
The causes and consequences of genetic heterogeneity in cancer evolution
2013 StandoutNature
Crucial role of p53-dependent cellular senescence in suppression of Pten-deficient tumorigenesis
2005 StandoutNature
CDK-dependent phosphorylation of BRCA2 as a regulatory mechanism for recombinational repair
2005 NatureNobel
Sirt1 promotes fat mobilization in white adipocytes by repressing PPAR-γ
2004 StandoutNature
Regulation of BRCC, a Holoenzyme Complex Containing BRCA1 and BRCA2, by a Signalosome-like Subunit and Its Role in DNA Repair
2003
The DNA damage response: putting checkpoints in perspective
2000 StandoutNature
Stat1-dependent and -independent pathways in IFN-γ-dependent signaling
2002
DNA-PKcs has KU-dependent function in rRNA processing and haematopoiesis
2020 StandoutNatureNobel
The Fanconi road to cancer: Figure 1.
2003
The role of senescent cells in ageing
2014 StandoutNature
Quantitative Proteomic Analysis of Cellular Protein Modulation upon Inhibition of the NEDD8-Activating Enzyme by MLN4924
2011
Exploring complex networks
2001 StandoutNature
BRCA1 Is Associated with a Human SWI/SNF-Related Complex
2000
Branch Migration and Holliday Junction Resolution Catalyzed by Activities from Mammalian Cells
2001
Oxygen Sensing, Homeostasis, and Disease
2011 StandoutNobel
Role of BRCA2 in Control of the RAD51 Recombination and DNA Repair Protein
2001
Cancer-related inflammation
2008 StandoutNature
Integrins
2002 Standout
Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan
2003 StandoutNature
Proteomics to study genes and genomes
2000 StandoutNature
The HIN-200 family: More than interferon-inducible genes?
2005
Inflammasomes in health and disease
2012 StandoutNature
Peptidic degron in EID1 is recognized by an SCF E3 ligase complex containing the orphan F-box protein FBXO21
2015 StandoutNobel
Convergence of Wnt, ß-Catenin, and Cadherin Pathways
2004 StandoutScience
Structure of an XRCC1 BRCT domain: a new protein-protein interaction module
1998 StandoutNobel
The Bcl-2 Protein Family: Arbiters of Cell Survival
1998 StandoutScience
Deficiency of human BRCA2 leads to impaired homologous recombination but maintains normal nonhomologous end joining
2001
Molecular Interaction Map of the Mammalian Cell Cycle Control and DNA Repair Systems
1999 Nobel
Reconstitution of RPA-covered single-stranded DNA-activated ATR-Chk1 signaling
2010 StandoutNobel
CBP/p300 in cell growth, transformation, and development
2000
Physiology meets biophysics: Visualizing the interaction of hypoxia-inducible factor 1α with p300 and CBP
2002 StandoutNobel
Rb-Mediated Heterochromatin Formation and Silencing of E2F Target Genes during Cellular Senescence
2003 Standout
Following the Path of the Virus: The Exploitation of Host DNA Repair Mechanisms by Retroviruses
2006
Cancer Immunoediting: Integrating Immunity’s Roles in Cancer Suppression and Promotion
2011 StandoutScience
Epac is a Rap1 guanine-nucleotide-exchange factor directly activated by cyclic AMP
1998 StandoutNature
Antiviral Actions of Interferons
2001 Standout
Integrin Signaling
1999 StandoutScience
cis -Diammine(pyridine)chloroplatinum(II), a monofunctional platinum(II) antitumor agent: Uptake, structure, function, and prospects
2008 StandoutNobel
PD-L1 and PD-L2 are differentially regulated by Th1 and Th2 cells
2003 StandoutNobel
Requirement of ATM-Dependent Phosphorylation of Brca1 in the DNA Damage Response to Double-Strand Breaks
1999 Science
Toll-related receptors and the control of antimicrobial peptide expression inDrosophila
2000 StandoutNobel
The signals and pathways activating cellular senescence
2004
The Ubiquitin-Proteasome Pathway and Its Role in Cancer
2005
Integrin-mediated Activation of Focal Adhesion Kinase Is Required for Signaling to Jun NH2-terminal Kinase and Progression through the G1 Phase of the Cell Cycle
1999
HdmX stimulates Hdm2-mediated ubiquitination and degradation of p53
2003 StandoutNobel
Genetically encoded fluorescent reporters of protein tyrosine kinase activities in living cells
2001 StandoutNobel
Suppression of Lymphoma and Epithelial Malignancies Effected by Interferon γ
2002
The p53-dependent effects of macrophage migration inhibitory factor revealed by gene targeting
2003
Human DNA Repair Genes
2001 StandoutScienceNobel
The adaptor protein Crk connects multiple cellular stimuli to the JNK signaling pathway
1998
Multiple Click-Selective tRNA Synthetases Expand Mammalian Cell-Specific Proteomics
2018 StandoutNobel
Mitochondrial activation chemicals synergize with surface receptor PD-1 blockade for T cell-dependent antitumor activity
2017 StandoutNobel
A phosphatidylinositol 3-kinase/Akt pathway promotes translocation of Mdm2 from the cytoplasm to the nucleus
2001
Mechanism of Action and In Vivo Role of Platelet-Derived Growth Factor
1999 Standout
Works of Toru Ouchi being referenced
STAT1-induced Apoptosis Is Mediated by Caspases 2, 3, and 7
2004
A member of the Pyrin family, IFI16, is a novel BRCA1-associated protein involved in the p53-mediated apoptosis pathway
2003
Overexpression of aurora kinase A in mouse mammary epithelium induces genetic instability preceding mammary tumor formation
2006
BRCA1 phosphorylation: Biological consequences
2006
Requirement of IFI16 for the Maximal Activation of p53 Induced by Ionizing Radiation
2004
DNA damage induces reactive oxygen species generation through the H2AX-Nox1/Rac1 pathway
2012
IFI16 as a Negative Regulator in the Regulation of p53 and p21Waf1
2003
Cell Cycle Differences in DNA Damage-induced BRCA1 Phosphorylation Affect Its Subcellular Localization
2003
BRCA1 shifts p53-mediated cellular outcomes towards irreversible growth arrest
2003
Autoubiquitination of the BRCA1·BARD1 RING Ubiquitin Ligase
2002
Collaboration of signal transducer and activator of transcription 1 (STAT1) and BRCA1 in differential regulation of IFN-γ target genes
2000
Sustained activation of Ras/Raf/mitogen-activated protein kinase cascade by the tumor suppressor p53
2000
Tumor Suppressor p53 Is Required To Modulate BRCA1 Expression
2000
BRCA1 regulates p53-dependent gene expression
1998
BRCA1 Phosphorylation Regulates Caspase-3 Activation in UV-Induced Apoptosis
2005
Downstream of Crk adaptor signaling pathway: Activation of Jun kinase by v-Crk through the guanine nucleotide exchange protein C3G
1997
The BRCA 2 gene product functionally interacts with p53 and RAD51
1998