Citation Impact
Citing Papers
GPCR Engineering Yields High-Resolution Structural Insights into β 2 -Adrenergic Receptor Function
2007 StandoutScienceNobel
Hypogonadotropic hypogonadism due to loss of function of the KiSS1-derived peptide receptor GPR54
2003 Standout
Persistently elevated T cell interferon-gamma responses after treatment for latent tuberculosis infection among health care workers in India: a preliminary report.
2006
Platelet factor 4–induced T H 1-T reg polarization suppresses antitumor immunity
2024 StandoutScienceNobel
β-Arrestin-dependent, G Protein-independent ERK1/2 Activation by the β2 Adrenergic Receptor
2005 StandoutNobel
Protean Effects of a Natural Peptide Agonist of the G Protein-Coupled Secretin Receptor Demonstrated by Receptor Mutagenesis
1998
Protein Kinase A and G Protein-coupled Receptor Kinase Phosphorylation Mediates β-1 Adrenergic Receptor Endocytosis through Different Pathways
2003 StandoutNobel
Comparison of two commercial interferon-γ assays for diagnosingMycobacterium tuberculosisinfection
2006
Regulation of the hypothalamic corticotropin-releasing hormone neurosecretory system
1993
Discrepancy Between the Tuberculin Skin Test and the Whole-Blood Interferon γ Assay for the Diagnosis of Latent Tuberculosis Infection in an Intermediate Tuberculosis-Burden Country
2005
Omental and Subcutaneous Adipose Tissues of Obese Subjects Release Interleukin-6: Depot Difference and Regulation by Glucocorticoid1
1998
The Hypothalamic–Pituitary–Adrenal Axis and Immune-Mediated Inflammation
1995 Standout
Body Fatness and Cancer — Viewpoint of the IARC Working Group
2016 Standout
Exoloop 3 of the Luteinizing Hormone/Choriogonadotropin Receptor
1996
Diversity and Prevalence of Somatic Mutations in the Thyrotropin Receptor and Gsα Genes as a Cause of Toxic Thyroid Adenomas1
1997
Distinct β-Arrestin- and G Protein-dependent Pathways for Parathyroid Hormone Receptor-stimulated ERK1/2 Activation
2006 StandoutNobel
Recent developments in constitutive receptor activity and inverse agonism, and their potential for GPCR drug discovery
2006
Effect of Thyroid Hormones on Cardiac Function, Geometry, and Oxidative Metabolism Assessed Noninvasively by Positron Emission Tomography and Magnetic Resonance Imaging
2000
Palmitoylation of CCR5 Is Critical for Receptor Trafficking and Efficient Activation of Intracellular Signaling Pathways
2001
Constitutive Activation of G Protein-Coupled Receptors as a Result of Selective Substitution of a Conserved Leucine Residue in Transmembrane Helix III
2000
The spectrum of latent tuberculosis: rethinking the biology and intervention strategies
2009 Standout
Minireview: Constitutively Active G Protein-Coupled Receptors: Potential Mechanisms of Receptor Activation
1997
Opioid receptor random mutagenesis reveals a mechanism for G protein–coupled receptor activation
2003
Detecting Latent Tuberculosis Infection in Hemodialysis Patients
2006
Interferon-γ assays in the immunodiagnosis of tuberculosis: a systematic review
2004 Standout
Susceptibility genes in Graves’ ophthalmopathy: searching for a needle in a haystack?
2007
Thyroid Hormone and the Cardiovascular System
2001 Standout
The Luteinizing Hormone/Chorionic Gonadotropin Receptor Has Distinct Transmembrane Conductors for cAMP and Inositol Phosphate Signals
1996
Performance of a whole blood interferon gamma assay for detecting latent infection with Mycobacterium tuberculosis in children
2006
Tuberculosis in Patients with Human Immunodeficiency Virus Infection
1999 Standout
Lys583 in the Third Extracellular Loop of the Lutropin/Choriogonadotropin Receptor Is Critical for Signaling
1996
G Protein-coupled Receptors
1998 StandoutNobel
Wnt/β-Catenin Signaling and Disease
2012 Standout
Graves' Ophthalmopathy
2010 Standout
Isoniazid prophylaxis differently modulates T-cell responses to RD1-epitopes in contacts recently exposed to Mycobacterium tuberculosis: a pilot study
2007
The Ectodomain of the Luteinizing Hormone Receptor Interacts with Exoloop 2 to Constrain the Transmembrane Region
2002 StandoutNobel
Constitutive activation of the TSH receptor by spontaneous mutations affecting the N‐terminal extracellular domain
1997
Differential effects of NaCl concentration on the constitutive activity of the thyrotropin and the luteinizing hormone/chorionic gonadotropin receptors
1996
Low Sensitivity of a Whole‐Blood Interferon‐γ Release Assay for Detection of Active Tuberculosis
2006
The microenvironment of the tumour–host interface
2001 StandoutNature
Synergistic roles of interleukin-6, interleukin-1, and tumor necrosis factor in the adrenocorticotropin response to bacterial lipopolysaccharide in vivo.
1993
The structure and function of G-protein-coupled receptors
2009 StandoutNatureNobel
The Impact of the Gut Microbiota on Human Health: An Integrative View
2012 Standout
Air pollution and health
2002 Standout
A Membrane-proximal Basic Domain and Cysteine Cluster in the C-terminal Tail of CCR5 Constitute a Bipartite Motif Critical for Cell Surface Expression
2001 StandoutNobel
Short-term Effects of Ambient Oxidant Exposure on Mortality: A Combined Analysis within the APHEA Project
1997
Respiratory Diseases and <i>Helicobacter pylori</i> Infection: Is There a Link?
2006
The Three Subfamilies of Leucine-Rich Repeat-Containing G Protein-Coupled Receptors (LGR): Identification of LGR6 and LGR7 and the Signaling Mechanism for LGR7
2000
Association of thyrotrophin receptor antibodies with the clinical features of Graves' ophthalmopathy
2000
Reactivation of Tuberculosis During Immunosuppressive Treatment in a Patient with a Positive QuantiFERON®-RD1 Test
2004
Maternal Thyroid Deficiency during Pregnancy and Subsequent Neuropsychological Development of the Child
1999 Standout
The Carboxyl Terminus of Human Cytomegalovirus-encoded 7 Transmembrane Receptor US28 Camouflages Agonism by Mediating Constitutive Endocytosis
2003
Accuracy of an immune diagnostic assay based on RD1 selected epitopes for active tuberculosis in a clinical setting: a pilot study
2006
Activation of the Luteinizing Hormone Receptor Following Substitution of Ser-277 with Selective Hydrophobic Residues in the Ectodomain Hinge Region
2000 StandoutNobel
Antigen-induced apoptotic death of Ly-1 B cells responsible for autoimmune disease in transgenic mice
1992 StandoutNatureNobel
Origin and physiological roles of inflammation
2008 StandoutNature
Receptors and G proteins as primary components of transmembrane signal transduction
1995
The Epidemiology of Tuberculosis in San Francisco -- A Population-Based Study Using Conventional and Molecular Methods
1994
Reduced Cell Surface Expression of CCR5 in CCR5Δ32 Heterozygotes Is Mediated by Gene Dosage, Rather Than by Receptor Sequestration
2002 StandoutNobel
Regulation of T Cell Receptor CD3ζ Chain Expression byl-Arginine
2002
Use in routine clinical practice of two commercial blood tests for diagnosis of infection with Mycobacterium tuberculosis: a prospective study
2006
Mycobacterium tuberculosis Infection in Health Care Workers in Rural India
2005
A Yeast Genetic Screen Reveals a Critical Role for the Pore Helix Domain in TRP Channel Gating
2008 StandoutNobel
G protein-coupled receptor structure and function: The impact of disease-causing mutations
1995
Comparison of a whole blood interferon-γ assay with tuberculin skin testing for the detection of tuberculosis infection in hospitalized children in rural India
2006
Acute-Phase Proteins and Other Systemic Responses to Inflammation
1999 Standout
Co-expression of Defective Luteinizing Hormone Receptor Fragments Partially Reconstitutes Ligand-induced Signal Generation
1997 StandoutNobel
Obesity is associated with macrophage accumulation in adipose tissue
2003 Standout
Tuberculosis contact investigation with a new, specific blood test in a low-incidence population containing a high proportion of BCG-vaccinated persons
2006
Latent Tuberculosis in HIV positive, diagnosed by the M. Tuberculosis Specific Interferon-γ test
2006
Protein Kinase A-mediated Phosphorylation of the β2-Adrenergic Receptor Regulates Its Coupling to Gs and Gi
2002 StandoutNobel
Clinical Utility of Thyrotropin-Receptor Antibody Assays: Comparison of Radioreceptor and Bioassay Methods
1988
Biomarkers for tuberculosis disease activity, cure, and relapse
2009
Transmembrane Regions V and VI of the Human Luteinizing Hormone Receptor Are Required for Constitutive Activation by a Mutation in the Third Intracellular Loop
1996 StandoutNobel
Risk for Tuberculosis among Children
2006
Depressed Thyroid Function Following Paediatric Cardiopulmonary Bypass: Association with Interleukin-6 Release?
1996
Enzyme-linked Immunospot and Tuberculin Skin Testing to Detect Latent Tuberculosis Infection
2005
Serial Testing of Health Care Workers for Tuberculosis Using Interferon-γ Assay
2006
Routine Hospital Use of a New Commercial Whole Blood Interferon-γ Assay for the Diagnosis of Tuberculosis Infection
2005
Role of the Rate of Internalization of the Agonist-Receptor Complex on the Agonist-Induced Down-Regulation of the Lutropin/ Choriogonadotropin Receptor
1999
Quantitative Comparison of Active and Latent Tuberculosis in the Cynomolgus Macaque Model
2009
Involutional Osteoporosis
1986 Standout
The Thyrotropin (TSH)-Releasing Hormone Receptor: Interaction with TSH and Autoantibodies*
1998
Effect of Thyroid Hormones on Cardiac Function, Geometry, and Oxidative Metabolism Assessed Noninvasively by Positron Emission Tomography and Magnetic Resonance Imaging
2000
EVIDENCE FOR THYROID-GROWTH-STIMULATING IMMUNOGLOBULINS IN SOME GOITROUS THYROID DISEASES
1980
Meta-analysis: New Tests for the Diagnosis of Latent Tuberculosis Infection: Areas of Uncertainty and Recommendations for Research
2007 Standout
Solvent-Free Organic Synthesis
2000 StandoutNobel
An Anionic Residue at Position 564 Is Important for Maintaining the Inactive Conformation of the Human Lutropin/Choriogonadotropin Receptor
1998
Air Pollution and Pulmonary Tuberculosis: A Nested Case–Control Study among Members of a Northern California Health Plan
2016
Naturally Occurring Mutations of the Luteinizing-Hormone Receptor: Lessons Learned about Reproductive Physiology and G Protein–Coupled Receptors
1999
Changes in Thyroid-Stimulating Antibody Activity in Graves' Disease Treated with Antithyroid Drug and Its Relationship to Relapse: A Prospective Study*
1980
Regulation of Receptor Fate by Ubiquitination of Activated β 2 -Adrenergic Receptor and β-Arrestin
2001 StandoutScienceNobel
Characterization of Two Fly LGR (Leucine-Rich Repeat-Containing, G Protein-Coupled Receptor) Proteins Homologous to Vertebrate Glycoprotein Hormone Receptors: Constitutive Activation of Wild-Type Fly LGR1 But Not LGR2 in Transfected Mammalian Cells**This study was supported by NIH Grant HD-23273. The GenBank submission number for fly LGR2 is AF274591.
2000
Carbon−Carbon Coupling Reactions Catalyzed by Heterogeneous Palladium Catalysts
2006 Standout
Insight into Graves’ Hyperthyroidism from Animal Models
2005
A missense mutation in the second transmembrane segment of the luteinizing hormone receptor causes familial male-limited precocious puberty.
1995
Direct effects of ethanol on bone resorption and formation in vitro
1985
THE LUTEINIZING HORMONE RECEPTOR
1998
Comparison of a New ESAT-6/CFP-10 Peptide-Based Gamma Interferon Assay and a Tuberculin Skin Test for Tuberculosis Screening in a Moderate-Risk Population
2006
Interferon-gamma release assays and TB screening in high-income countries: a cost-effectiveness analysis.
2007
Transient Hypothyroidism in Infants Born to Mothers with Chronic Thyroiditis-A Nationwide Study of Twenty-three Cases.
1990
A Transgenic Model of Visceral Obesity and the Metabolic Syndrome
2001 StandoutScience
Activation of Orphan Receptors by the Hormone Relaxin
2002 StandoutScience
Maternal Care, Hippocampal Glucocorticoid Receptors, and Hypothalamic-Pituitary-Adrenal Responses to Stress
1997 StandoutScience
Guidelines for Using the QuantiFERON-TB Gold Test for Detecting Mycobacterium tuberculosis Infection, United States
2005
FUNCTIONAL AND STRUCTURAL COMPLEXITY OF SIGNAL TRANSDUCTION VIA G-PROTEIN-COUPLED RECEPTORS
1997
Oral administration of lipopolysaccharides activates B-1 cells in the peritoneal cavity and lamina propria of the gut and induces autoimmune symptoms in an autoantibody transgenic mouse.
1994 StandoutNobel
Development and Evaluation of a Method for the Partial Purification of Immunoglobulins Specific for Graves’ Disease*
1981
Evaluation of an In Vitro Assay for Interferon γ Production in Response to theMycobacterium tuberculosis–Synthesized Peptide Antigens ESAT-6 and CFP-10 and the PPD Skin Test
2006
Autoimmunity - A Perspective
1983
Transient Neonatal Hypothyroidism Due to Transplacental Transfer of Maternal Immunoglobulins that Inhibit TSH Binding, TSH-Induced cAMP Increase and Cell Growth.
1988
Immunology of Autoimmune Thyroid Diseases
1982 Standout
Organic Reactions in Aqueous Media with a Focus on Carbon−Carbon Bond Formations: A Decade Update
2005 Standout
G PROTEIN–COUPLED RECEPTOR KINASES
1998 StandoutNobel
Inverse agonism of amino-terminally truncated parathyroid hormone (PTH) and PTH-related peptide (PTHrP) analogs revealed with constitutively active mutant PTH/PTHrP receptors.
1996
Current Perspective on the Pathogenesis of Graves’ Disease and Ophthalmopathy
2003
Recombinant interleukin-6 activates the hypothalamic-pituitary-adrenal axis in humans.
1993
Hypothalamic-pituitary-adrenal axis activation and stimulation of systemic vasopressin secretion by recombinant interleukin-6 in humans: potential implications for the syndrome of inappropriate vasopressin secretion.
1994
Fine Particulate Air Pollution and Mortality in 20 U.S. Cities, 1987–1994
2000 Standout
The adipocyte: a model for integration of endocrine and metabolic signaling in energy metabolism regulation
2001
Estrogen Replacement Therapy: Indications and Complications
1983
THYROTROPHIN BINDING INHIBITING IMMUNOGLOBULINS IN GRAVES' DISEASE BEFORE, DURING AND AFTER ANTITHYROID THERAPY, AND ITS RELATION TO LONG‐ACTING THYROID STIMULATOR
1980
Solid state photochemistry of methyl-substituted benzophenones
1987
Organic photochemistry in organized media
1986
Mutations of Gonadotropins and Gonadotropin Receptors: Elucidating the Physiology and Pathophysiology of Pituitary-Gonadal Function
2000
Regulation of the Hypothalamic-Pituitary-Adrenal Axis by Cytokines: Actions and Mechanisms of Action
1999
The Stimulation of Thyroid Hormone Secretion in Vitro by Thyroid-Stimulating Antibodies*
1981
G-protein-coupled Receptor (GPCR) Kinase Phosphorylation and β-Arrestin Recruitment Regulate the Constitutive Signaling Activity of the Human Cytomegalovirus US28 GPCR
2003 StandoutNobel
Systematic Review: T-Cell–based Assays for the Diagnosis of Latent Tuberculosis Infection: An Update
2008
Transduction of Receptor Signals by ß-Arrestins
2005 StandoutScienceNobel
A highly active and reusable heterogeneous catalyst for the Suzuki reaction: synthesis of biaryls and polyaryls
2003
Constitutive Activation of the Cyclic Adenosine 3′,5′-Monophosphate Signaling Pathway by Parathyroid Hormone (PTH)/PTH-Related Peptide Receptors Mutated at the Two Loci for Jansen’s Metaphyseal Chondrodysplasia
1997
Lysophospholipid Growth Factors in the Initiation, Progression, Metastases, and Management of Ovarian Cancer
2000
Works of Toru Mori being referenced
Radioimmunoassay for Human Calcitonin Employing Synthetic Calcitonin M: Ist clinical Application
1975
Characterization of heterogeneous mutations causing constitutive activation of the luteinizing hormone receptor in familial male precocious puberty
1995
Liver-type arginase in serum during and after liver transplantation: a novel index in monitoring conditions of the liver graft and its clinical significance
1998
The first cytoplasmic loop of the thyrotropin receptor is important for phosphoinositide signaling but not for agonist‐induced adenylate cyclase activation
1994
Presence of heterogeneous thyroid-stimulating antibodies in sera from individual Graves' patients as shown by synthesized thyrotropin receptor peptide application: evidence showing two independent epitopes and a possible recognition of two epitopic regions by one antibody molecule
1995
The third exoplasmic loop of the thyrotropin receptor is partially involved in signal transduction
1994
Constitutive activation of cyclic AMP but not phosphatidylinositol signaling caused by four mutations in the 6th transmembrane helix of the human thyrotropin receptor
1994
Establishment and Characterization of an Antihuman Thyrotropin (TSH) Receptor-Specific CD4 + T Cell Line from a Patient with Graves' Disease: Evidence for Multiple T Cell Epitopes on the TSH Receptor Including the Transmembrane Domain
1995
Screening for Tuberculosis Infection Using Whole-Blood Interferon-γ and Mantoux Testing Among Japanese Healthcare Workers
2006
Correlation of HLA types and clinical findings in Japanese patients with hyperthyroid Graves' disease: evidence indicating the existence of four subpopulations
1992
Personal Exposure to Nitrogen Dioxide and Its Association with Respiratory Illness in Hong Kong
1990
A synthetic oligopeptide derived from human thyrotropin receptor sequence binds to Graves' immunoglobulin and inhibits thyroid stimulating antibody activity but lacks interactions with TSH
1991
Correlation between suspended particles in the environmental air and causes of disease among inhabitants: Cross-sectional studies using the vital statistics and air pollution data in Japan
2005
Cytokines and endocrine function: an interaction between the immune and neuroendocrine systems
1991
Further Studies of Amino Acids (268–304) in Thyrotropin (TSH)-Lutropin/Chorionic Gonadotropin (LH/CG) Receptor Chimeras: Cysteine-301 Is Important in TSH Binding and Receptor Tertiary Structure
1994
Cysteine-699, a Possible Palmitoylation Site of the Thyrotropin Receptor, Is Not Crucial for cAMP or Phosphoinositide Signaling but Is Necessary for Full Surface Expression
1996
Interferon‐γ responses after isoniazid chemotherapy for latent tuberculosis
2008
The Role of Asp578 in Maintaining the Inactive Conformation of the Human Lutropin/Choriogonadotropin Receptor
1996
Thyroid-stimulating antibodies in sera from patients with Graves' disease are heterogeneous in epitope recognition
1995
Prolonged Effects of Recombinant Human Interleukin-1 α on Mouse Thyroid Function*
1990
Possible binding site of thyrotropin binding inhibitor immunoglobulin (TBII) on the thyrotropin (TSH) receptor, which is different from TSH binding site
1990
Relationship between whole-blood interferon-gamma responses and the risk of active tuberculosis
2008
Specific Detection of Tuberculosis Infection
2004
Photodimerization of 1,4-dicinnamoylbenzene crystal via a topochemical process
1984
Purification of TSH Receptor from Porcine Thyroid Membrane and Effect of Various Protease Inhibitors on Receptor Stability.
1988
Detection and Properties of TSH-Binding Inhibitor Immunoglobulins in Patients with Graves’ Disease and Hashimoto’s Thyroiditis*
1978
Genetic differences shown by HLA typing among Japanese patients with euthyroid Graves' ophthalmopathy, Graves' disease and Hashimoto's thyroiditis: genetic characteristics of euthyroid Graves' ophthalmopathy
1991
TSH Receptor and LH Receptor, 1995.
1995
Topochemical double photocyclodimerization of the 1,4-dicinnamoylbenzene crystal
1985
Studies of anin VitroBinding Reaction Between Thyroid Microsomes and Long Acting Thyroid Stimulator Globulin (LATS): I. Development of Solid-State Competitive Binding Radioassay Methods for Measurement of Antimicrosomal and Antithyroglobulin Antibodies1
1970
[Usefulness of QuantiFERON TB-2G in contact investigation of a tuberculosis outbreak in a university].
2005
[Basic characteristics of a novel diagnostic method (QuantiFERON TB-2G) for latent tuberculosis infection with the use of Mycobacterium tuberculosis-specific antigens, ESAT-6 and CFP-10].
2004
Myocardial oxidative metabolism in hyperthyroid patients assessed by PET with carbon-11-acetate.
1995
A New in Vitro Assay for Human Thyroid Stimulator Using Cultured Thyroid Cells: Effect of Sodium Chloride on Adenosine 3′,5′-Monophosphate Increase*
1982
Disappearance of Blocking Type Thyrotropin Binding Inhibitor Immunoglobulin (TBII) during Thyroid and Steroid Medication in a Patient with Autoimmune Thyroiditis
1987
Photoreactions of Polyhalobenzenes in Benzene. Formation of Terphenyls
1989
Inhibition of Thyrotropin-Induced Adenosine 3′5′-Monophosphate Increase by Immunoglobulins from Patients with Primary Myxedema*
1983
Restriction Fragment Length Polymorphism Analysis of Epidemiologically Related Mycobacterium tuberculosis Isolates
1993
A predicted case with neonatal transient hypothyroidism due to blocking type thyrotropin binding inhibitor immunoglobulins (TBII)
1985