Standout Papers
- Genetic Influences on Brain Gene Expression in Rats Selected for Tameness and Aggression (2014)
- The Rise and Fall of the Chemoattractant Receptor GPR33 (2005)
- Targeted resequencing of a genomic region influencing tameness and aggression reveals multiple signals of positive selection (2011)
- Genetic Architecture of Tameness in a Rat Model of Animal Domestication (2009)
- Phenotypic differences in behavior, physiology and neurochemistry between rats selected for tameness and for defensive aggression towards humans (2007)
Citation Impact
Citing Papers
Activity-Dependent Internalization of Smoothened Mediated by ß-Arrestin 2 and GRK2
2004 StandoutScienceNobel
High-Resolution Crystal Structure of an Engineered Human β 2 -Adrenergic G Protein–Coupled Receptor
2007 StandoutScienceNobel
GPCR Engineering Yields High-Resolution Structural Insights into β 2 -Adrenergic Receptor Function
2007 StandoutScienceNobel
Dishevelled 2 Recruits ß-Arrestin 2 to Mediate Wnt5A-Stimulated Endocytosis of Frizzled 4
2003 StandoutScienceNobel
Keeping G Proteins at Bay: A Complex Between G Protein-Coupled Receptor Kinase 2 and Gßγ
2003 StandoutScienceNobel
The 2.6 Angstrom Crystal Structure of a Human A 2A Adenosine Receptor Bound to an Antagonist
2008 StandoutScience
Computational design of soluble and functional membrane protein analogues
2024 StandoutNatureNobel
Latrophilins Function as Heterophilic Cell-adhesion Molecules by Binding to Teneurins
2013 StandoutNobel
GPCR activation mechanisms across classes and macro/microscales
2021
DATING OF THE HOMINID (HOMO NEANDERTHALENSIS) REMAINS ACCUMULATION FROM EL SIDRÓN CAVE (PILOÑA, ASTURIAS, NORTH SPAIN): AN EXAMPLE OF A MULTI‐METHODOLOGICAL APPROACH TO THE DATING OF UPPER PLEISTOCENE SITES
2009
Rapid identification of functionally critical amino acids in a G protein–coupled receptor
2007
Identification of an amino acid residue important for binding of methiothepin and sumatriptan to the human 5-HT1B receptor
1999
Increased Basal Activity Is a Key Determinant in the Severity of Human Skeletal Dysplasia Caused by TRPV4 Mutations
2011
Proboscidean Mitogenomics: Chronology and Mode of Elephant Evolution Using Mastodon as Outgroup
2007
Extracellular Mutations of Protease-Activated Receptor-1 Result in Differential Activation by Thrombin and Thrombin Receptor Agonist Peptide
2000
Essential role for the second extracellular loop in C5a receptor activation
2005
CD22 blockade restores homeostatic microglial phagocytosis in ageing brains
2019 StandoutNatureNobel
Pronounced Conformational Changes following Agonist Activation of the M3 Muscarinic Acetylcholine Receptor
2005
Constitutive Activation of G Protein-Coupled Receptors as a Result of Selective Substitution of a Conserved Leucine Residue in Transmembrane Helix III
2000
PSF and p54nrb/NonO – multi‐functional nuclear proteins
2002
Crystal structure of the human β2 adrenergic G-protein-coupled receptor
2007 StandoutNatureNobel
Agonists induce conformational changes in transmembrane domains III and VI of the beta 2 adrenoceptor
1997
High-resolution crystal structure of human protease-activated receptor 1
2012 StandoutNatureNobel
Transient receptor potential channelopathies
2010
An alpha-carbon template for the transmembrane helices in the rhodopsin family of G-protein-coupled receptors 1 1Edited by R. Huber
1997
Toward the active conformations of rhodopsin and the β2‐adrenergic receptor
2004
Roof and Floor of the Muscarinic Binding Pocket: Variations in the Binding Modes of Orthosteric Ligands
2007
Phagocytosis of apoptotic cells in homeostasis
2015
The complete mitochondrial DNA genome of an unknown hominin from southern Siberia
2010 StandoutNatureNobel
Alternate Coupling of Receptors to Gs and Gi in Pancreatic and Submandibular Gland Cells
1999
The Fourth Transmembrane Segment Forms the Interface of the Dopamine D2 Receptor Homodimer
2003
Identification of ancient remains through genomic sequencing
2008
Conformational Changes That Occur during M3Muscarinic Acetylcholine Receptor Activation Probed by the Use of an in Situ Disulfide Cross-linking Strategy
2002
Neanderthals in central Asia and Siberia
2007 StandoutNatureNobel
Ligand-specific regulation of the extracellular surface of a G-protein-coupled receptor
2010 StandoutNatureNobel
Structure of the human M2 muscarinic acetylcholine receptor bound to an antagonist
2012 StandoutNatureNobel
G Protein-coupled Receptors
1998 StandoutNobel
The Ectodomain of the Luteinizing Hormone Receptor Interacts with Exoloop 2 to Constrain the Transmembrane Region
2002 StandoutNobel
Crystal structure of the β2 adrenergic receptor–Gs protein complex
2011 StandoutNatureNobel
Multiple Residues in the Second Extracellular Loop Are Critical for M3 Muscarinic Acetylcholine Receptor Activation
2007
The structure and function of G-protein-coupled receptors
2009 StandoutNatureNobel
Ancient DNA extraction from bones and teeth
2007 Standout
Molecular modeling of adenosine receptors: new results and trends
2007
In Situ Generation of Wavelength‐Shifting Donor–Acceptor Mixed‐Monolayer‐Modified Surfaces
2010 StandoutNobel
Human occludin is a hepatitis C virus entry factor required for infection of mouse cells
2009 StandoutNatureNobel
Structure of the TRPV1 ion channel determined by electron cryo-microscopy
2013 StandoutNatureNobel
The Three Subfamilies of Leucine-Rich Repeat-Containing G Protein-Coupled Receptors (LGR): Identification of LGR6 and LGR7 and the Signaling Mechanism for LGR7
2000
From micrograms to picograms: quantitative PCR reduces the material demands of high-throughput sequencing
2007 StandoutNobel
Structure of a nanobody-stabilized active state of the β2 adrenoceptor
2011 StandoutNatureNobel
An early modern human from Romania with a recent Neanderthal ancestor
2015 StandoutNatureNobel
Claudin-1 is a hepatitis C virus co-receptor required for a late step in entry
2007 StandoutNatureNobel
Activation of the Luteinizing Hormone Receptor Following Substitution of Ser-277 with Selective Hydrophobic Residues in the Ectodomain Hinge Region
2000 StandoutNobel
Phylogenetic analysis of 277 human G-protein-coupled receptors as a tool for the prediction of orphan receptor ligands
2002
Demystifying the three dimensional structure of G protein-coupled receptors (GPCRs) with the aid of molecular modeling
2003
Crystal structure of the µ-opioid receptor bound to a morphinan antagonist
2012 StandoutNatureNobel
Removal of deaminated cytosines and detection of in vivo methylation in ancient DNA
2009 StandoutNobel
Seven-transmembrane-spanning receptors and heart function
2002 StandoutNatureNobel
Serine and alanine mutagenesis of the nine native cysteine residues of the human A1 adenosine receptor
2000
Structure of a β1-adrenergic G-protein-coupled receptor
2008 StandoutNatureNobel
Role of claudins in tumorigenesis
2005
Transmembrane proteins of tight junctions
2007
A Proposed Structure for Transmembrane Segment 7 of G Protein-Coupled Receptors Incorporating an Asn-Pro/Asp-Pro Motif
1998
Structure and dynamics of the M3 muscarinic acetylcholine receptor
2012 StandoutNatureNobel
Co-expression of Defective Luteinizing Hormone Receptor Fragments Partially Reconstitutes Ligand-induced Signal Generation
1997 StandoutNobel
Protein Kinase A-mediated Phosphorylation of the β2-Adrenergic Receptor Regulates Its Coupling to Gs and Gi
2002 StandoutNobel
Site-directed mutagenesis of the putative human muscarinic M2 receptor binding site
1999
Allosteric Receptors after 30 Years
1998
Analysis of one million base pairs of Neanderthal DNA
2006 StandoutNatureNobel
Transmembrane Regions V and VI of the Human Luteinizing Hormone Receptor Are Required for Constitutive Activation by a Mutation in the Third Intracellular Loop
1996 StandoutNobel
Scanning Mutagenesis Studies of the M 1 Muscarinic Acetylcholine Receptor
2003
Enhanced Morphine Analgesia in Mice Lacking β-Arrestin 2
1999 StandoutScienceNobel
Roles of G‐protein‐coupled receptor dimerization
2004
The Thyrotropin (TSH)-Releasing Hormone Receptor: Interaction with TSH and Autoantibodies*
1998
G Protein-coupled Receptors
1998
Patterns of nucleotide misincorporations during enzymatic amplification and direct large-scale sequencing of ancient DNA
2006 StandoutNobel
Identification of a receptor/G-protein contact site critical for signaling specificity and G-protein activation.
1995
Characterization of Two Fly LGR (Leucine-Rich Repeat-Containing, G Protein-Coupled Receptor) Proteins Homologous to Vertebrate Glycoprotein Hormone Receptors: Constitutive Activation of Wild-Type Fly LGR1 But Not LGR2 in Transfected Mammalian Cells**This study was supported by NIH Grant HD-23273. The GenBank submission number for fly LGR2 is AF274591.
2000
Phenotypic traits of primate hybrids: Recognizing admixture in the fossil record
2010
G Protein–Coupled Receptor Oligomerization
2004
MOD-1 is a serotonin-gated chloride channel that modulates locomotory behaviour in C. elegans
2000 StandoutNatureNobel
CLAUDINS AND EPITHELIAL PARACELLULAR TRANSPORT
2005
μ-Opioid receptor desensitization by β-arrestin-2 determines morphine tolerance but not dependence
2000 StandoutNatureNobel
Connectivity and orientation of the seven helical bundle in the tachykinin NK-1 receptor probed by zinc site engineering.
1996
The second extracellular loop of the dopamine D2receptor lines the binding-site crevice
2004
β-Arrestin 2: A Receptor-Regulated MAPK Scaffold for the Activation of JNK3
2000 StandoutScienceNobel
Uncovering Molecular Mechanisms Involved in Activation of G Protein-Coupled Receptors
2000
Structure-Function of the G Protein–Coupled Receptor Superfamily
2012
Glutamate residues in the second extracellular loop of the human A2a adenosine receptor are required for ligand recognition.
1996
Computational Modeling Approaches to Structure−Function Analysis of G Protein-Coupled Receptors
2005
G PROTEIN–COUPLED RECEPTOR KINASES
1998 StandoutNobel
Mutagenesis Reveals Structure−Activity Parallels between Human A2AAdenosine Receptors and Biogenic Amine G Protein-Coupled Receptors
1997
Neuroscience: Breaking Down Scientific Barriers to the Study of Brain and Mind
2000 StandoutScienceNobel
International Union of Pharmacology. XXV. Nomenclature and Classification of Adenosine Receptors
2001 Standout
Update 1 of: Computational Modeling Approaches to Structure–Function Analysis of G Protein-Coupled Receptors
2011
PERIOD1-Associated Proteins Modulate the Negative Limb of the Mammalian Circadian Oscillator
2005 StandoutScienceNobel
The makers of the Protoaurignacian and implications for Neandertal extinction
2015 StandoutScienceNobel
New Tricks with Old Bones
2008 Science
Targeted Investigation of the Neandertal Genome by Array-Based Sequence Capture
2010 StandoutScienceNobel
ß-Arrestin 2 Mediates Endocytosis of Type III TGF-ß Receptor and Down-Regulation of Its Signaling
2003 StandoutScienceNobel
Transduction of Receptor Signals by ß-Arrestins
2005 StandoutScienceNobel
Targeted Retrieval and Analysis of Five Neandertal mtDNA Genomes
2009 StandoutScienceNobel
Works of Torsten Schöneberg being referenced
The GPS Motif Is a Molecular Switch for Bimodal Activities of Adhesion Class G Protein-Coupled Receptors
2012
Interdomain Interactions Control Ca2+-Dependent Potentiation in the Cation Channel TRPV4
2010
Conserved Extracellular Cysteine Pair in the M3 Muscarinic Acetylcholine Receptor Is Essential for Proper Receptor Cell Surface Localization but Not for G Protein Coupling
1999
The Fate of Desmosomal Proteins in Apoptotic Cells
2001
A novel subgroup of class I G-protein-coupled receptors
1999
Site-directed Mutagenesis Identifies Residues Involved in Ligand Recognition in the Human A2a Adenosine Receptor
1995
Severe Congenital Hyperthyroidism Caused by a Germ-LineneoMutation in the Extracellular Portion of the Thyrotropin Receptor1
1998
Structural basis of G protein-coupled receptor function
1999
Multiplex amplification of ancient DNA
2006
Mutational Analysis of the Relative Orientation of Transmembrane Helices I and VII in G Protein-coupled Receptors
1995
Evolution of GPCR: Change and continuity
2010
A Surface‐Modified Dendrimer Set for Potential Application as Drug Delivery Vehicles: Synthesis, In Vitro Toxicity, and Intracellular Localization
2004
Parallel Selection on TRPV6 in Human Populations
2008
Mutations of the Human Thyrotropin Receptor Gene Causing Thyroid Hypoplasia and Persistent Congenital Hypothyroidism1
1997
Structural Implication for Receptor Oligomerization from Functional Reconstitution Studies of Mutant V2 Vasopressin Receptors
2000
Mutations in G Protein–Coupled Receptors: Mechanisms, Pathophysiology and Potential Therapeutic Approaches
2020
Nuclear Gene Indicates Coat-Color Polymorphism in Mammoths
2006 Science
Nuclear envelope proteomics: Novel integral membrane proteins of the inner nuclear membrane
2001
Functional rescue of mutant V2 vasopressin receptors causing nephrogenic diabetes insipidus by a co-expressed receptor polypeptide.
1996
The specific fates of tight junction proteins in apoptotic epithelial cells
2004
Role of the Third Intracellular Loop for the Activation of Gonadotropin Receptors
1999
A conserved tyrosine residue (Y601) in transmembrane domain 5 of the human thyrotropin receptor serves as a molecular switch to determine G‐protein coupling
1998
Inhibition of Gonadotropin-Releasing Hormone Receptor Signaling by Expression of a Splice Variant of the Human Receptor
1997
FUNCTIONAL AND STRUCTURAL COMPLEXITY OF SIGNAL TRANSDUCTION VIA G-PROTEIN-COUPLED RECEPTORS
1997
A Melanocortin 1 Receptor Allele Suggests Varying Pigmentation Among Neanderthals
2007 Science
Adhesion G Protein-coupled Receptors
2016
Claudin-2 expression induces cation-selective channels in tight junctions of epithelial cells
2002