Citation Impact
Citing Papers
Disruption of Autophagy at the Maturation Step by the Carcinogen Lindane Is Associated with the Sustained Mitogen-Activated Protein Kinase/Extracellular Signal–Regulated Kinase Activity
2006
A selective PIKfyve inhibitor blocks PtdIns(3,5)P 2 production and disrupts endomembrane transport and retroviral budding
2008
Differential Antigen Processing by Dendritic Cell Subsets in Vivo
2007 StandoutScienceNobel
Autophagy Plays a Critical Role in the Degradation of Active RHOA, the Control of Cell Cytokinesis, and Genomic Stability
2013
Autophagy Sustains Pancreatic Cancer Growth through Both Cell-Autonomous and Nonautonomous Mechanisms
2018
Atg6 is required for multiple vesicle trafficking pathways and hematopoiesis in Drosophila
2013
TOR Signaling in Growth and Metabolism
2006 Standout
Dedicated SNARE s and specialized TRIM cargo receptors mediate secretory autophagy
2016
Regulation of phosphoinositide 3-kinase expression in health and disease
2009
The Role of Autophagy in Drosophila Metamorphosis
2013
Autophagy Controls the Kinetics and Extent of Mitochondrial Apoptosis by Regulating PUMA Levels
2014
Discovery and functional interrogation of SARS-CoV-2 RNA-host protein interactions
2021 StandoutNobel
Hallmarks of Cancer: The Next Generation
2011 Standout
Hyperactive Innate Immunity Causes Degeneration of Dopamine Neurons upon Altering Activity of Cdk5
2019
Cargo recognition and trafficking in selective autophagy
2014
Promoting basal levels of autophagy in the nervous system enhances longevity and oxidant resistance in adult Drosophila
2008
PIKfyve Regulation of Endosome‐Linked Pathways
2009
ArPIKfyve Homomeric and Heteromeric Interactions Scaffold PIKfyve and Sac3 in a Complex to Promote PIKfyve Activity and Functionality
2008
Does Autophagy Contribute To Cell Death?
2005
RILP interacts with the VPS22 component of the ESCRT-II complex
2006
Two-step process for photoreceptor formation in Drosophila
2001 Nature
Specificity in Signal Transduction
2004
ATG12–ATG3 interacts with Alix to promote basal autophagic flux and late endosome function
2015
A Role for Ubiquitin in Selective Autophagy
2009
Inflammation and metabolic disorders
2006 StandoutNature
Physical Principles of Membrane Shape Regulation by the Glycocalyx
2019 StandoutNobel
Hearing in Drosophila: Development of Johnston's organ and emerging parallels to vertebrate ear development
2005
Lysosomes: fusion and function
2007 Standout
Role and Regulation of Starvation-Induced Autophagy in the Drosophila Fat Body
2004
Autophagy Regulates Programmed Cell Death during the Plant Innate Immune Response
2005
Male-specific fruitless specifies the neural substrates of Drosophila courtship behaviour
2005 StandoutNatureNobel
Dynamic control of neuroexocytosis by phosphoinositides in health and disease
2010
Autophagy and signaling: their role in cell survival and cell death
2005
The role of autophagy in neurodegenerative disease
2013 Standout
RILP interacts with VPS22 and VPS36 of ESCRT-II and regulates their membrane recruitment
2006
Exosomes and Autophagy: Coordinated Mechanisms for the Maintenance of Cellular Fitness
2014
Multivesicular bodies: co-ordinated progression to maturity
2008
Differential Regulation of Distinct Vps34 Complexes by AMPK in Nutrient Stress and Autophagy
2013
Degradation of Endocytosed Epidermal Growth Factor and Virally Ubiquitinated Major Histocompatibility Complex Class I Is Independent of Mammalian ESCRTII
2005
Autophagy is involved in T cell death after binding of HIV-1 envelope proteins to CXCR4
2006
Genome-wide analysis of Notch signalling in Drosophila by transgenic RNAi
2009 Nature
Eaten alive: a history of macroautophagy
2010 Standout
Vesicular trafficking and autophagosome formation
2009
Autophagy fights disease through cellular self-digestion
2008 StandoutNature
Membrane budding and scission by the ESCRT machinery: it's all in the neck
2010
Identification of BRCA1-IRIS, a BRCA1 locus product
2004
Endosomal and non-endosomal functions of ESCRT proteins
2006
Antimicrobial Autophagy: A Conserved Innate Immune Response in Drosophila
2013 Standout
Active Interaction Mapping Reveals the Hierarchical Organization of Autophagy
2017
Direct Induction of Autophagy by Atg1 Inhibits Cell Growth and Induces Apoptotic Cell Death
2007
Cytonemes are required for the establishment of a normal Hedgehog morphogen gradient in Drosophila epithelia
2013
Rab GTPases as coordinators of vesicle traffic
2009 Standout
A Protein's Final ESCRT
2004
Biological Functions of Autophagy Genes: A Disease Perspective
2019 Standout
PIKfyve-ArPIKfyve-Sac3 Core Complex
2009
Autophagy Signaling and the Cogwheels of Cancer
2006
Autophagy and Tumor Metabolism
2017
Assaying autophagic activity in transgenic GFP-Lc3 and GFP-Gabarap zebrafish embryos
2009
ESCRT & Co
2010
Autophagy, Not Apoptosis, Is Essential for Midgut Cell Death in Drosophila
2009
Membrane protein sequestering by ionic protein–lipid interactions
2011 StandoutNatureNobel
The Ubiquitin‐Vacuolar Protein Sorting System is Selectively Required During Entry of Influenza Virus into Host Cells
2003
Synthetic Par polarity induces cytoskeleton asymmetry in unpolarized mammalian cells
2023 StandoutNobel
The ESCRT complexes
2010
Differential Use of Two AP‐3‐mediated Pathways by Lysosomal Membrane Proteins
2004
Morphogen gradient interpretation by a regulated trafficking step during ligand–receptor transduction
2005 StandoutNobel
Rapamycin fed late in life extends lifespan in genetically heterogeneous mice
2009 StandoutNature
Vps-C complexes: gatekeepers of endolysosomal traffic
2009
The structure and function of G-protein-coupled receptors
2009 StandoutNatureNobel
The Selective Macroautophagic Degradation of Aggregated Proteins Requires the PI3P-Binding Protein Alfy
2010
Self-consumption: the interplay of autophagy and apoptosis
2014 Standout
Autophagy Regulates Chromatin Ubiquitination in DNA Damage Response through Elimination of SQSTM1/p62
2016
Growth Factor Regulation of Autophagy and Cell Survival in the Absence of Apoptosis
2005
Emerging functions of the VCP/p97 AAA-ATPase in the ubiquitin system
2012
The Steroid Hormone Ecdysone Controls Systemic Growth by Repressing dMyc Function in Drosophila Fat Cells
2010
Methods in Mammalian Autophagy Research
2010 Standout
Sar1p N-Terminal Helix Initiates Membrane Curvature and Completes the Fission of a COPII Vesicle
2005 StandoutNobel
Multivesicular bodies in neurons: Distribution, protein content, and trafficking functions
2011
Autophagy modulation as a potential therapeutic target for diverse diseases
2012 Standout
CRISPR screening using an expanded toolkit of autophagy reporters identifies TMEM41B as a novel autophagy factor
2019
Beclin1-binding UVRAG targets the class C Vps complex to coordinate autophagosome maturation and endocytic trafficking
2008
Developmental and cellular functions of the ESCRT machinery in pluricellular organisms
2010
Autophagy inhibitors
2015
Autophagy Is an Essential Component of Drosophila Immunity against Vesicular Stomatitis Virus
2009
Growth Arrest and Autophagy Are Required for Salivary Gland Cell Degradation in Drosophila
2007
ESCRT-I Core and ESCRT-II GLUE Domain Structures Reveal Role for GLUE in Linking to ESCRT-I and Membranes
2006
Loss of autophagy in the central nervous system causes neurodegeneration in mice
2006 StandoutNature
Genome-Scale Identification of SARS-CoV-2 and Pan-coronavirus Host Factor Networks
2020 StandoutNobel
Origin and physiological roles of inflammation
2008 StandoutNature
The PtdIns(3,4)P2 phosphatase INPP4A is a suppressor of excitotoxic neuronal death
2010 StandoutNatureNobel
A Lumenal Domain-Dependent Pathway for Sorting to Intralumenal Vesicles of Multivesicular Endosomes Involved in Organelle Morphogenesis
2006
Receptor-mediated selective autophagy degrades the endoplasmic reticulum and the nucleus
2015 StandoutNatureNobel
Targeting autophagy in cancer
2017 Standout
Class II MHC peptide loading by the professionals
2003
Tumor Suppressor Properties of the ESCRT-II Complex Component Vps25 in Drosophila
2005
Autophagy in cell death: an innocent convict?
2005 Standout
Endosome maturation
2011 Standout
Autophagy in Spinal Cord Motor Neurons in Sporadic Amyotrophic Lateral Sclerosis
2011
The role of autophagy during the early neonatal starvation period
2004 StandoutNatureNobel
Signalome-wide RNAi screen identifies GBA1 as a positive mediator of autophagic cell death
2017
Autophagy: process and function
2007 Standout
Activation of autophagy during cell death requires the engulfment receptor Draper
2010 Nature
Toward unraveling membrane biogenesis in mammalian autophagy
2008
Macrophage biology in development, homeostasis and disease
2013 StandoutNature
Tollip and Tom1 Form a Complex and Recruit Ubiquitin-conjugated Proteins onto Early Endosomes
2004
The ESCRT Pathway
2011
Genetic aberrations in macroautophagy genes leading to diseases
2018
Uba1 functions in Atg7- and Atg3-independent autophagy
2013
The emerging shape of the ESCRT machinery
2007
The selective autophagy substrate p62 activates the stress responsive transcription factor Nrf2 through inactivation of Keap1
2010 Standout
Protein Sequence Editing of SKN-1A/Nrf1 by Peptide:N-Glycanase Controls Proteasome Gene Expression
2019 StandoutNobel
TMEM41B Is a Pan-flavivirus Host Factor
2020 StandoutNobel
Autophagic control of listeria through intracellular innate immune recognition in drosophila
2008
Autophagy Inhibition Compromises Degradation of Ubiquitin-Proteasome Pathway Substrates
2009
Cell death by autophagy: facts and apparent artefacts
2011
PIKfyve: Partners, significance, debates and paradoxes
2008
Autophagy: A Forty-Year Search for a Missing Membrane Source
2006
The crosstalk between microtubules, actin and membranes shapes cell division
2020
The structural and energetic basis for high selectivity in a high-affinity protein-protein interaction
2010 StandoutNobel
An Atg1/Atg13 Complex with Multiple Roles in TOR-mediated Autophagy Regulation
2009
Conservation of the Keap1-Nrf2 System: An Evolutionary Journey through Stressful Space and Time
2017
Phosphatidylinositol 3,5-bisphosphate and Fab1p/PIKfyve underPPIn endo-lysosome function
2009
The ESCRT-III Subunit hVps24 Is Required for Degradation but Not Silencing of the Epidermal Growth Factor Receptor
2006
Calpain is required for macroautophagy in mammalian cells
2006
Ramshackle (Brwd3) promotes light-induced ubiquitylation of Drosophila Cryptochrome by DDB1-CUL4-ROC1 E3 ligase complex
2013 StandoutNobel
One-Component Multifunctional Sequence-Defined Ionizable Amphiphilic Janus Dendrimer Delivery Systems for mRNA
2021 StandoutNobel
Biogenesis and Function of Multivesicular Bodies
2007
ATG Systems from the Protein Structural Point of View
2009 StandoutNobel
Biogenesis and Cargo Selectivity of Autophagosomes
2011
Regulation Mechanisms and Signaling Pathways of Autophagy
2009 Standout
Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes
2008 Standout
TheCaenorhabditis elegans spalt-like genesem-4restricts touch cell fate by repressing the selector Hox geneegl-5and the effector genemec-3
2003 StandoutNobel
Stapled Peptide Inhibitors of Autophagy Adapter LC3B
2020
Functional multivesicular bodies are required for autophagic clearance of protein aggregates associated with neurodegenerative disease
2007
Down-regulation of epidermal growth factor receptor signalling within multivesicular bodies
2009
DrosophilaVps16A is required for trafficking to lysosomes and biogenesis of pigment granules
2005
Regulation of GPCRs by Endocytic Membrane Trafficking and Its Potential Implications
2007
Regulation of Caenorhabditis elegans neuronal polarity by heterochronic genes
2019 StandoutNobel
The Ubiquitin-Proteasome System Plays an Important Role during Various Stages of the Coronavirus Infection Cycle
2010
ADAPTORS FOR CLATHRIN COATS: Structure and Function
2004
Regulation of membrane traffic by phosphoinositide 3-kinases
2006
RETROVIRUS BUDDING
2004
Drosophila Melted Modulates FOXO and TOR Activity
2005
Mvb12 Is a Novel Member of ESCRT-I Involved in Cargo Selection by the Multivesicular Body Pathway
2006
THE ESCRT COMPLEXES: Structure and Mechanism of a Membrane-Trafficking Network
2006
Autophagosome formation from membrane compartments enriched in phosphatidylinositol 3-phosphate and dynamically connected to the endoplasmic reticulum
2008 Standout
Regulation of autophagy by mTOR-dependent and mTOR-independent pathways: autophagy dysfunction in neurodegenerative diseases and therapeutic application of autophagy enhancers
2013
BRCA1-IRIS promotes human tumor progression through PTEN blockade and HIF-1α activation
2018 StandoutNobel
Amyloid precursor protein (APP) traffics from the cell surface via endosomes for amyloid β (Aβ) production in the trans -Golgi network
2012 StandoutNobel
Sudestada1, a Drosophila ribosomal prolyl-hydroxylase required for mRNA translation, cell homeostasis, and organ growth
2014 StandoutNobel
Imaging and imagination: understanding the endo-lysosomal system
2008
New component of ESCRT-I regulates endosomal sorting complex assembly
2006
Role of the mammalian retromer in sorting of the cation-independent mannose 6-phosphate receptor
2004
The Multifaceted Roles of Autophagy in Flavivirus-Host Interactions
2018
RILP is required for the proper morphology and function of late endosomes
2007
Stapled β-Hairpins Featuring 4-Mercaptoproline
2021 StandoutNobel
mTOR Pathway as a Target in Tissue Hypertrophy
2006
Normal development is an integral part of tumorigenesis in T cell-specific PTEN-deficient mice
2008 StandoutNobel
Unique double-ring structure of the peroxisomal Pex1/Pex6 ATPase complex revealed by cryo-electron microscopy
2015 StandoutNobel
The vacuolar ATPase is required for physiological as well as pathological activation of the Notch receptor
2010
Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation
2009 StandoutScience
Recent insights into cell death and autophagy
2015
Regulation of Mammalian Autophagy in Physiology and Pathophysiology
2010 Standout
Modulating Macroautophagy: A Neuronal Perspective
2012
Works of Tor Erik Rusten being referenced
Cell death duringDrosophila melanogasterearly oogenesis is mediated through autophagy
2009
Shaping development with ESCRTs
2011
ESCRT functions in autophagy and associated disease
2008
A dual function for Deep orange in programmed autophagy in the Drosophila melanogaster fat body
2006
Analyzing phosphoinositides and their interacting proteins
2006
Disruption of Vps4 and JNK Function in Drosophila Causes Tumour Growth
2009
Multiple functions of the SNARE protein Snap29 in autophagy, endocytic, and exocytic trafficking during epithelial formation inDrosophila
2014
The PI 3-kinase regulator Vps15 is required for autophagic clearance of protein aggregates
2008
Microenvironmental autophagy promotes tumour growth
2017 Nature
Characterization and tissue expression of acidic fibroblast growth factor binding protein homologue in Drosophila melanogaster
2003
ESCRTs and Fab1 Regulate Distinct Steps of Autophagy
2007
p62/Sequestosome-1, Autophagy-related Gene 8, and Autophagy in Drosophila Are Regulated by Nuclear Factor Erythroid 2-related Factor 2 (NRF2), Independent of Transcription Factor TFEB
2015
Programmed Autophagy in the Drosophila Fat Body Is Induced by Ecdysone through Regulation of the PI3K Pathway
2004
PtdIns(3)P controls cytokinesis through KIF13A-mediated recruitment of FYVE-CENT to the midbody
2010
Protein sorting into multivesicular endosomes
2003
Comparative analysis of ESCRT-I, ESCRT-II and ESCRT-III function inDrosophilaby efficient isolation of ESCRT mutants
2009
Fab1 Phosphatidylinositol 3-Phosphate 5-Kinase Controls Trafficking but Not Silencing of Endocytosed Receptors
2006
Regulation of Early Endosomal Entry by theDrosophilaTumor Suppressors Rabenosyn and Vps45
2008
Genetic Modifiers of the Drosophila Blue Cheese Gene Link Defects in Lysosomal Transport With Decreased Life Span and Altered Ubiquitinated-Protein Profiles
2007
Phosphoinositide 3-kinases as accelerators and brakes of autophagy
2013
Spalt modifies EGFR-mediated induction of chordotonal precursors in the embryonic PNS of Drosophila promoting the development of oenocytes
2001
How do ESCRT proteins control autophagy?
2009
Ref(2)P, the Drosophila melanogaster homologue of mammalian p62, is required for the formation of protein aggregates in adult brain
2008
Autophagic degradation of dBruce controls DNA fragmentation in nurse cells during late Drosophila melanogaster oogenesis
2010
Membrane remodeling by the PX-BAR protein SNX18 promotes autophagosome formation
2013