Standout Papers

Aquaporin-4 deletion in mice reduces brain edema after acute water intoxication and ischemic s... 2000 2026 2008 2017 1.3k
  1. Aquaporin-4 deletion in mice reduces brain edema after acute water intoxication and ischemic stroke (2000)
    Geoffrey T. Manley, Miki Fujimura et al. Nature Medicine

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Citing Papers

IgG marker of optic-spinal multiple sclerosis binds to the aquaporin-4 water channel
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Expression and Functional Analysis of Water Channels in a Stably AQP2-transfected Human Collecting Duct Cell Line
1996
Water Channel Properties of Major Intrinsic Protein of Lens
1995 StandoutNobel
The aquaporin family of membrane water channels
1994 StandoutNobel
Molecular Cloning and Characterization of an Aquaporin cDNA from Salivary, Lacrimal, and Respiratory Tissues
1995 StandoutNobel
Oligomerization State of MIP Proteins Expressed in Xenopus Oocytes as Revealed by Freeze-Fracture Electron-Microscopy Analysis
1999
Localization of aquaporin‐5 in sweat glands and functional analysis using knockout mice
2002
Projection Structure of the CHIP28 Water Channel in Lipid Bilayer Membranes at 12-.ANG. Resolution
1994
A refined structure of human aquaporin‐1
2001
An aquaporin-2 water channel mutant which causes autosomal dominant nephrogenic diabetes insipidus is retained in the Golgi complex.
1998
Nephrogenic Diabetes Insipidus
2006
Developmental changes in water permeability across the alveolar barrier in perinatal rabbit lung.
1997
Molecular Cloning and Characterization of AqpZ, a Water Channel from Escherichia coli
1995 StandoutNobel
Molecular Cloning and Characterization of an Insect Aquaporin
1996
Selectivity of the Renal Collecting Duct Water Channel Aquaporin-3
1996
Molecular Characterization of a Broad Selectivity Neutral Solute Channel
1998
The importance of aquaporin water channel protein structures
2000 StandoutNobel
Pattern-specific loss of aquaporin-4 immunoreactivity distinguishes neuromyelitis optica from multiple sclerosis
2007
Switch from an Aquaporin to a Glycerol Channel by Two Amino Acids Substitution
1999
Renal Expression of Aquaporins in Liver Cirrhosis Induced by Chronic Common Bile Duct Ligation in Rats
1999
Molecular Cloning and Expression of a Novel Human Aquaporin from Adipose Tissue with Glycerol Permeability
1997
Transport of Water and Glycerol in Aquaporin 3 Is Gated by H+
1999
Aquaporins in the kidney: Emerging new aspects
1998
Cloning and Functional Expression of a Second New Aquaporin Abundantly Expressed in Testis
1997
Aquaporin water channels: molecular mechanisms for human diseases1
2003 StandoutNobel
Rat renal arcade segment expresses vasopressin-regulated water channel and vasopressin V2 receptor.
1996
Bidirectional Water Fluxes and Specificity for Small Hydrophilic Molecules in Aquaporins 0–5
1998
Ion currents of Xenopus laevis oocytes: state of the art
1999
Aquaporin Water Channels in Kidney
2000 StandoutNobel
Persistent increase in the amount of aquaporin‐5 in the apical plasma membrane of rat parotid acinar cells induced by a muscarinic agonist SNI‐2011
2000
The structure of aquaporins
2006
Rapid gating and anion permeability of an intracellular aquaporin
1999 StandoutNatureNobel
Regulation of Aquaporin-4 Water Channels by Phorbol Ester-dependent Protein Phosphorylation
1998
A Yeast Recombinant Aquaporin Mutant That Is Not Expressed or Mistargeted in Xenopus Oocyte Can Be Functionally Analyzed in Reconstituted Proteoliposomes
1998
Freeze-Fracture Analysis of Plasma Membranes of CHO Cells Stably Expressing Aquaporins 1-5
1998
The three-dimensional structure of aquaporin-1
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Renal aquaporins
1996
Adenovirus-mediated Expression of Aquaporin-5 in Epithelial Cells
1996 StandoutNobel
Acetylcholine Acts on M3Muscarinic Receptors and Induces the Translocation of Aquaporin5 Water Channel via Cytosolic Ca2+Elevation in Rat Parotid Glands
1998
Cryo-EM structure of the protein-conducting ERAD channel Hrd1 in complex with Hrd3
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Ultrastructure, Pharmacologic Inhibition, and Transport Selectivity of Aquaporin CHIP in Proteoliposomes
1994 StandoutNobel
Evidence for the Presence of Aquaporin-3 in Human Red Blood Cells
1998
Salivary Acinar Cells from Aquaporin 5-deficient Mice Have Decreased Membrane Water Permeability and Altered Cell Volume Regulation
2001
The aquaporin family of water channels in kidney
1995 StandoutNobel
Distribution of mRNA encoding the FA-CHIP water channel in amphibian tissues: Effects of salt adaptation
1995
Physiology and pathophysiology of renal aquaporins
2001
Ion Permeation of AQP6 Water Channel Protein
2002 StandoutNobel
Structural determinants of water permeation through aquaporin-1
2000 StandoutNatureNobel
Abnormal Distribution of Aquaporin-5 Water Channel Protein in Salivary Glands from Sjögren's Syndrome Patients
2001 StandoutNobel
Isolation of Human Aquaporin 3 Gene
1995
Molecular characterization of human Aquaporin-7 gene and its chromosomal mapping
1998
Structure of the water channel AqpZ from Escherichia coli revealed by electron crystallography
1999 StandoutNobel
Aquaporins and the respiratory system: advice for a lung investigator
2000 StandoutNobel
The Fold of Human Aquaporin 1
2000
Intra-cerebral injection of neuromyelitis optica immunoglobulin G and human complement produces neuromyelitis optica lesions in mice
2010
Role of renal aquaporins in escape from vasopressin-induced antidiuresis in rat.
1997
Expression of aquaporin-4 in fast-twitch fibers of mammalian skeletal muscle.
1998
Phosphorylation of Serine 256 Is Required for cAMP-dependent Regulatory Exocytosis of the Aquaporin-2 Water Channel
1997
Decreased Abundance of Collecting Duct Aquaporins in Post-Ischemic Renal Failure in Rats
1999
Immunolocalization of Aquaporin Homologs in Mouse Lacrimal Glands
1997
Water and Glycerol Permeabilities of Aquaporins 1–5 and MIP Determined Quantitatively by Expression of Epitope-tagged Constructs inXenopus Oocytes
1997
Genetic mouse models to study blood–brain barrier development and function
2013
Aquaporin-5 Dependent Fluid Secretion in Airway Submucosal Glands
2001
Development, maintenance and disruption of the blood-brain barrier
2013 Standout
Fps1p controls the accumulation and release of the compatible solute glycerol in yeast osmoregulation
1999
Aquaporin Adipose, a Putative Glycerol Channel in Adipocytes
2000
Evidence for a glycerol pathway through aquaporin 1 (CHIP28) channels
1995
The Aquaporins, Blueprints for Cellular Plumbing Systems
1998 StandoutNobel
Defective Urinary Concentrating Ability Due to a Complete Deficiency of Aquaporin-1
2001 StandoutNobel
Cloning of a New Aquaporin (AQP10) Abundantly Expressed in Duodenum and Jejunum
2001
Cloning and Functional Expression of a New Water Channel Abundantly Expressed in the Testis Permeable to Water, Glycerol, and Urea
1997
Three-dimensional organization of a human water channel
1997 Nature
Comparison of the Water Transporting Properties of MIP and AQP1
1997
Aquaporin water channels: unanswered questions and unresolved controversies
1995 StandoutNobel
Structural Analysis of a MIP Family Protein from the Digestive Tract of Cicadella viridis
1995
The role of aquaporins in cellular and whole plant water balance
2000
The AQP2 water channel: Effect of vasopressin treatment, microtubule disruption, and distribution in neonatal rats
1995
Structure of Aquaporin-2 Vasopressin Water Channel
1996
An impaired routing of wild-type aquaporin-2 after tetramerization with an aquaporin-2 mutant explains dominant nephrogenic diabetes insipidus
1999
The wacA gene of Dictyostelium discoideum is a developmentally regulated member of the MIP family
1997
Progress on the Structure and Function of Aquaporin 1
1998 StandoutNobel
Studies of Renal Aquaporin-2 Expression during Renal Escape from Vasopressin-Induced Antidiuresis
1998
Aquaporin water channels – from atomic structure to clinical medicine
2002 StandoutNobel
Functional reconstitution and characterization of AqpZ, the E. coli water channel protein
1999 StandoutNobel
Human red cell aquaporin CHIP. I. Molecular characterization of ABH and Colton blood group antigens.
1994 StandoutNobel
Aquaporins: water selective channels in biological membranes. Molecular structure and tissue distribution
1994
Freeze-fracture and immunogold analysis of aquaporin-4 (AQP4) square arrays, with models of AQP4 lattice assembly
2004
The Human Aquaporin-5 Gene
1996 StandoutNobel
The disturbed blood–brain barrier in human glioblastoma
2012
ABH and Colton blood group antigens on Aquaporin-1, the human red cell water channel protein
1995 StandoutNobel
Immunogold evidence suggests that coupling of K+ siphoning and water transport in rat retinal M�ller cells is mediated by a coenrichment of Kir4.1 and AQP4 in specific membrane domains
1999
Examination of rat salivary glands for the presence of the aquaporin CHIP
1994
Vasopressin Type-2 Receptor and Aquaporin-2 Water Channel Mutants in Nephrogenic Diabetes Insipidus
1998
Renal aquaporins
1998
Dysregulation of renal aquaporins and Na-Cl cotransporter in CCl4-induced cirrhosis
2000
Oligomerization State of Water Channels and Glycerol Facilitators
1998
Functional Expression and Characterization of an Archaeal Aquaporin
2003 StandoutNobel
Structural clues in the sequences of the aquaporins
2000
Physiological importance of aquaporins: lessons from knockout mice
2000
cAMP Regulated Membrane Diffusion of a Green Fluorescent Protein-Aquaporin 2 Chimera
2000
The aquaporin family of water channels in kidney: An update on physiology and pathophysiology of aquaporin-2
1996 StandoutNobel
Hypertonic Induction of Aquaporin-5 Expression through an ERK-dependent Pathway
2000 StandoutNobel
Physiology and Pathophysiology of Renal Aquaporinsa
1999
Regulation of Aquaporin mRNA Expression in Rat Kidney by Water Intake
1999
Surface Topographies at Subnanometer-resolution Reveal Asymmetry and Sidedness of Aquaporin-1
1996 StandoutNobel
Cloning and Functional Expression of a New Aquaporin (AQP9) Abundantly Expressed in the Peripheral Leukocytes Permeable to Water and Urea, but Not to Glycerol
1998
Polarized distribution of key membrane transport proteins in the rat submandibular gland
1996
Expression and Localization of Epithelial Aquaporins in the Adult Human Lung
2001
Aquaporin-3 water channel localization and regulation in rat kidney
1995
Aquaporin‐4 deficiency in skeletal muscle and brain of dystrophic mdx mice
2001
The human AQP4 gene: definition of the locus encoding two water channel polypeptides in brain.
1996 StandoutNobel
Aquaporins: Water selective channels in biological membranes. Molecular structure and tissue distribution
1994
Aquaporins: water channel proteins of plant and animal cells
1994 StandoutNobel
The Mercurial Insensitive Water Channel (AQP-4) Forms Orthogonal Arrays in Stably Transfected Chinese Hamster Ovary Cells
1996
Aquaporins in complex tissues: distribution of aquaporins 1–5 in human and rat eye
1998 StandoutNobel
Salt and water transport across alveolar and distal airway epithelia in the adult lung
1996
Mutations in aquaporin-1 in Phenotypically Normal Humans Without Functional CHIP Water Channels
1994 StandoutScienceNobel
Molecular structure of the water channel through aquaporin CHIP. The hourglass model.
1994 StandoutNobel
Glial-conditional deletion of aquaporin-4 ( Aqp4 ) reduces blood–brain water uptake and confers barrier function on perivascular astrocyte endfeet
2011
Rapid amplification of a water channel-like gene and its flanking sequences from the Methanothermobacter marburgensis genome using a single primer PCR strategy
2001
Reconstitution and functional comparison of purified GlpF and AqpZ, the glycerol and water channels from Escherichia coli
2001 StandoutNobel
Immunolocalization of aquaporin-8 in rat kidney, gastrointestinal tract, testis, and airways
2001
An α-syntrophin-dependent pool of AQP4 in astroglial end-feet confers bidirectional water flow between blood and brain
2003 StandoutNobel
Compensatory increase in AQP2, p-AQP2, and AQP3 expression in rats with diabetes mellitus
2001
The three-dimensional structure of human erythrocyte aquaporin CHIP.
1994 StandoutNobel
Increased fluid secretion after adenoviral-mediated transfer of the aquaporin-1 cDNA to irradiated rat salivary glands
1997 StandoutNobel
Regulation of collecting duct water channel expression by vasopressin in Brattleboro rat.
1994
Expression and immunolocalization of aquaporin water channels in rat exocrine pancreas
2001
Aquaporin-4 Water Channel Protein in the Rat Retina and Optic Nerve: Polarized Expression in Müller Cells and Fibrous Astrocytes
1998 StandoutNobel
Visualization of a water-selective pore by electron crystallography in vitreous ice
2001
MOD-1 is a serotonin-gated chloride channel that modulates locomotory behaviour in C. elegans
2000 StandoutNatureNobel
The aquaporin family of molecular water channels.
1994
Reduced renal medullary water channel expression in puromycin aminonucleoside--induced nephrotic syndrome.
1997
An Aquaporin-Like Gene Required for the Brassica Self-Incompatibility Response
1997 Science
Regulation of AQP6 mRNA and protein expression in rats in response to altered acid-base or water balance
2000 StandoutNobel
Decreased vasopressin-mediated renal water reabsorption in rats with chronic aldosterone-receptor blockade
2000
Functional and molecular characterization of the human neutral solute channel aquaporin-9
1999
Phenotypic Heterogeneity of the Endothelium
2007
Transcellular water transport in lung alveolar epithelium through mercury-sensitive water channels.
1994
Water Permeation Across Biological Membranes: Mechanism and Dynamics of Aquaporin-1 and GlpF
2001 Science
Expression and localization of aquaporins in rat gastrointestinal tract
1999
Long-term regulation of four renal aquaporins in rats
1996
Functional characterization of a microbial aquaglyceroporin
2001
Aquaporin Z of Escherichia coli : Reassessment of Its Regulation and Physiological Role
2002
Immunolocalization of the mercurial-insensitive water channel and glycerol intrinsic protein in epithelial cell plasma membranes.
1995
Downregulation of AQP1, -2, and -3 after ureteral obstruction is associated with a long-term urine-concentrating defect
2001
Aquaporin-2 transfection of Madin-Darby canine kidney cells reconstitutes vasopressin-regulated transcellular osmotic water transport.
1997
Reduced abundance of aquaporins in rats with bilateral ischemia-induced acute renal failure: prevention by α-MSH
1999
Aquaporin null phenotypes: The importance of classical physiology
1998 StandoutNobel
Molecular characterization of an aquaporin cDNA from brain: candidate osmoreceptor and regulator of water balance.
1994 StandoutNobel
Functional independence of monomeric CHIP28 water channels revealed by expression of wild-type mutant heterodimers.
1994
Effect of expressing the water channel aquaporin-1 on the CO2 permeability ofXenopus oocytes
1998
Hourglass Pore-Forming Domains Restrict Aquaporin-1 Tetramer Assembly
1998 StandoutNobel
Dynamic mechanisms of the membrane water channel aquaporin-1 (AQP1)
2001
Biogenesis and transmembrane topology of the CHIP28 water channel at the endoplasmic reticulum.
1994
Decreased pulmonary vascular permeability in aquaporin-1-null humans
2002 StandoutNobel
AQUAPORINS AND WATER PERMEABILITY OF PLANT MEMBRANES
1997
Arginine vasopressin stimulates phosphorylation of aquaporin-2 in rat renal tissue
1999
Heterotetrameric Composition of Aquaporin-4 Water Channels
1999 StandoutNobel
Highly water-permeable type I alveolar epithelial cells confer high water permeability between the airspace and vasculature in rat lung
1998
Decreased vasopressin-mediated renal water reabsorption in rats with compensated liver cirrhosis
1998
Reconstitution of water channel function of aquaporins 1 and 2 by expression in yeast secretory vesicles
1998 StandoutNobel
Grid‐mapped freeze‐fracture analysis of gap junctions in gray and white matter of adult rat central nervous system, with evidence for a “panglial syncytium” that is not coupled to neurons
1997
AQUAPORIN-2 AND -3: Representatives of Two Subgroups of the Aquaporin Family Colocalized in the Kidney Collecting Duct
1998
Mercury-Sensitive Residues and Pore Site in AQP3 Water Channel
1997
Aquaporins in complex tissues. I. Developmental patterns in respiratory and glandular tissues of rat
1997 StandoutNobel
Congestive heart failure in rats is associated with increased expression and targeting of aquaporin-2 water channel in collecting duct
1997
Cloning and expression of AQP3, a water channel from the medullary collecting duct of rat kidney.
1994
Functional requirement of aquaporin-5 in plasma membranes of sweat glands
2002 StandoutNobel
The Aquaporin Family of Water Channel Proteins in Clinical Medicine
1997 StandoutNobel
Long-term regulation of aquaporins in the kidney
1999
The Water Channel Aquaporin-8 Is Mainly Intracellular in Rat Hepatocytes, and Its Plasma Membrane Insertion Is Stimulated by Cyclic AMP
2001
Cellular and Molecular Biology of the Aquaporin Water Channels
1999 StandoutNobel
Acute effects of vasopressin V2-receptor antagonist on kidney AQP2 expression and subcellular distribution
1998
Altered expression of renal AQPs and Na+transporters in rats with Lithium-induced NDI
2000
Urinary content of aquaporin 1 and 2 in nephrogenic diabetes insipidus.
1996
Water Channel Protein AQP3 Is Present in Epithelia Exposed to the Environment of Possible Water Loss
1999
Reduced AQP1, -2, and -3 levels in kidneys of rats with CRF induced by surgical reduction in renal mass
1998
Delayed onset of brain edema and mislocalization of aquaporin-4 in dystrophin-null transgenic mice
2002 StandoutNobel
Pathophysiology of the Aquaporin Water Channels
1996 StandoutNobel
Specialized Membrane Domains for Water Transport in Glial Cells: High-Resolution Immunogold Cytochemistry of Aquaporin-4 in Rat Brain
1997 StandoutNobel
Luminal hypotonicity in proximal tubules of aquaporin-1-knockout mice
2000
Very High Single Channel Water Permeability of Aquaporin-4 in Baculovirus-Infected Insect Cells and Liposomes Reconstituted with Purified Aquaporin-4
1997
Localization of MIWC and GLIP water channel homologs in neuromuscular, epithelial and glandular tissues
1995
Effect of AQP1 expression level on Co(2) permeability in bovine corneal endothelium.
2001
Identification and localization of aquaporin water channels in human salivary glands
2001
Aquaporins in the Kidney: From Molecules to Medicine
2002 StandoutNobel
The Structure of Aquaporin-1 at 4.5-Å Resolution Reveals Short α-Helices in the Center of the Monomer
1999 StandoutNobel
Direct immunogold labeling of aquaporin-4 in square arrays of astrocyte and ependymocyte plasma membranes in rat brain and spinal cord
1998 StandoutNobel
Aquaporin-4 square array assembly: Opposing actions of M1 and M23 isoforms
2003 StandoutNobel
Design of ordered two-dimensional arrays mediated by noncovalent protein-protein interfaces
2015 StandoutScienceNobel
Aquaporin-6: An intracellular vesicle water channel protein in renal epithelia
1999 StandoutNobel
Extrarenal tissue distribution of CHIP28 water channels by in situ hybridization and antibody staining
1994

Works of Tonghui Ma being referenced

Complement-dependent Cytotoxicity in Neuromyelitis Optica Requires Aquaporin-4 Protein Assembly in Orthogonal Arrays
2012
cDNA Cloning and Gene Structure of a Novel Water Channel Expressed Exclusively in Human Kidney: Evidence for a Gene Cluster of Aquaporins at Chromosome Locus 12q13
1996
Generation and phenotype of a transgenic knockout mouse lacking the mercurial-insensitive water channel aquaporin-4.
1997
Aquaporin water channels in gastrointestinal physiology
1999
Severely Impaired Urinary Concentrating Ability in Transgenic Mice Lacking Aquaporin-1 Water Channels
1998
Impaired Stratum Corneum Hydration in Mice Lacking Epidermal Water Channel Aquaporin-3
2002
Structure and function of kidney water channels
1995
Tear Secretion by Lacrimal Glands in Transgenic Mice Lacking Water Channels AQP1, AQP3, AQP4 and AQP5
2000
Cloning of a Novel Water and Urea-Permeable Aquaporin from Mouse Expressed Strongly in Colon, Placenta, Liver, and Heart
1997
Aquaporin-4 deletion in mice reduces brain edema after acute water intoxication and ischemic stroke
2000 Standout
cDNA Cloning, Gene Organization, and Chromosomal Localization of a Human Mercurial Insensitive Water Channel
1995
Reduced water permeability and altered ultrastructure in thin descending limb of Henle in aquaporin-1 null mice
1999
Requirement of aquaporin-1 for NaCl-driven water transport across descending vasa recta
2000
Closely Spaced Tandem Arrangement of AQP2, AQP5, and AQP6 Genes in a 27-Kilobase Segment at Chromosome Locus 12q13
1997
Lung fluid transport in aquaporin-1 and aquaporin-4 knockout mice
1999
Role of water channels in fluid transport studied by phenotype analysis of aquaporin knockout mice
2000
Role of aquaporins in alveolar fluid clearance in neonatal and adult lung, and in oedema formation following acute lung injury: studies in transgenic aquaporin null mice
2000
Gene Structure, cDNA Cloning, and Expression of a Mouse Mercurial-Insensitive Water Channel
1996
Defective Secretion of Saliva in Transgenic Mice Lacking Aquaporin-5 Water Channels
1999
cDNA and Genomic Cloning of Mouse Aquaporin-2: Functional Analysis of an Orthologous Mutant Causing Nephrogenic Diabetes Insipidus
1999
Distinct biogenesis mechanisms for the water channels MIWC and CHIP28 at the endoplasmic reticulum
1995
Carbon Dioxide Permeability of Aquaporin-1 Measured in Erythrocytes and Lung of Aquaporin-1 Null Mice and in Reconstituted Proteoliposomes
2000
Partial Correction of the Urinary Concentrating Defect in Aquaporin-1 Null Mice by Adenovirus-Mediated Gene Delivery
2000
Erythrocyte Water Permeability and Renal Function in Double Knockout Mice Lacking Aquaporin-1 and Aquaporin-3
2001
Cloning of a Novel Rat Kidney cDNA Homologous to CHIP28 and WCH-CD Water Channels
1993
Aquaporin-4 is expressed in basolateral membranes of proximal tubule S3 segments in mouse kidney
2000
Fourfold reduction of water permeability in inner medullary collecting duct of aquaporin-4 knockout mice
1998
Expression, functional analysis, and in situ hybridization of a cloned rat kidney collecting duct water channel
1994
Localization and functional analysis of CHIP28k water channels in stably transfected Chinese hamster ovary cells.
1993
Tetrameric assembly of CHIP28 water channels in liposomes and cell membranes: a freeze-fracture study.
1993
cDNA cloning of a functional water channel from toad urinary bladder epithelium
1996
Role of Aquaporin-4 in Airspace-to-Capillary Water Permeability in Intact Mouse Lung Measured by a Novel Gravimetric Method
1999
Skeletal muscle function and water permeability in aquaporin-4 deficient mice
2000
Defective proximal tubular fluid reabsorption in transgenic aquaporin-1 null mice
1998
A 28 kDa sarcolemmal antigen in kidney principal cell basolateral membranes: relationship to orthogonal arrays and MIP26
1994
Reduced osmotic water permeability of the peritoneal barrier in aquaporin-1 knockout mice
1999
Molecular cloning of a mercurial-insensitive water channel expressed in selected water-transporting tissues.
1994
Cloning of a water channel homolog expressed in brain meningeal cells and kidney collecting duct that functions as a stilbene-sensitive glycerol transporter.
1994
Role of aquaporin water channels in pleural fluid dynamics
2000
Water transport across mammalian cell membranes
1996
Constitutive and regulated membrane expression of aquaporin 1 and aquaporin 2 water channels in stably transfected LLC-PK1 epithelial cells.
1995
Nephrogenic diabetes insipidus in mice lacking aquaporin-3 water channels
2000
Absence of orthogonal arrays in kidney, brain and muscle from transgenic knockout mice lacking water channel aquaporin-4
1997
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