Citation Impact
Citing Papers
Computational protein design enables a novel one-carbon assimilation pathway
2015 StandoutNobel
High-throughput characterization of protein–protein interactions by reprogramming yeast mating
2017 StandoutNobel
Computational Stabilization of a Non‐Heme Iron Enzyme Enables Efficient Evolution of New Function
2024 StandoutNobel
Switchable Cas9
2017 StandoutNobel
A bacterial pathogen induces developmental slowing by high reactive oxygen species and mitochondrial dysfunction in Caenorhabditis elegans
2023 StandoutNobel
Controlling CRISPR-Cas9 with ligand-activated and ligand-deactivated sgRNAs
2019 StandoutNobel
Pretreatment of lignocellulose: Formation of inhibitory by-products and strategies for minimizing their effects
2015 Standout
A cell-free platform for the prenylation of natural products and application to cannabinoid production
2019 StandoutNobel
The re-emergence of natural products for drug discovery in the genomics era
2015 Standout
Dynamic combinatorial/covalent chemistry: a tool to read, generate and modulate the bioactivity of compounds and compound mixtures
2013
Improving stability of nitrile hydratase by bridging the salt-bridges in specific thermal-sensitive regions
2013
MACBETH: Multiplex automated Corynebacterium glutamicum base editing method
2018
Improving and repurposing biocatalysts via directed evolution
2015
Modular and tunable biological feedback control using a de novo protein switch
2019 StandoutNatureNobel
Multi-input chemical control of protein dimerization for programming graded cellular responses
2019 StandoutNobel
High‐Throughput Screening for Terpene‐Synthase‐Cyclization Activity and Directed Evolution of a Terpene Synthase
2013 StandoutNobel
Alzheimer's disease
2011 Standout
Exploiting and engineering hemoproteins for abiological carbene and nitrene transfer reactions
2017 StandoutNobel
Directed enzyme evolution: beyond the low-hanging fruit
2012
Engineering Complex Synthetic Transcriptional Programs with CRISPR RNA Scaffolds
2014
CRISPR/Cas9-based Genome Editing in Pseudomonas aeruginosa and Cytidine Deaminase-Mediated Base Editing in Pseudomonas Species
2018
Computational Library Design for Increasing Haloalkane Dehalogenase Stability
2014 StandoutNobel
Tau in physiology and pathology
2015 Standout
Profiling of engineering hotspots identifies an allosteric CRISPR-Cas9 switch
2016 StandoutNobel
The coming of age of de novo protein design
2016 StandoutNatureNobel
Stabilizing biocatalysts
2013
Combinatorial metabolic engineering using an orthogonal tri-functional CRISPR system
2017
FireProt: Energy- and Evolution-Based Computational Design of Thermostable Multiple-Point Mutants
2015 StandoutNobel
Genome editing with CRISPR–Cas nucleases, base editors, transposases and prime editors
2020 Standout
De novo design of bioactive protein switches
2019 StandoutNatureNobel
Diverse Engineered Heme Proteins Enable Stereodivergent Cyclopropanation of Unactivated Alkenes
2018 StandoutNobel
<p>Alzheimer’s disease: pathogenesis, diagnostics, and therapeutics</p>
2019 Standout
Tau oligomers and aggregation in Alzheimer’s disease
2009
Genome-wide mapping of mutations at single-nucleotide resolution for protein, metabolic and genome engineering
2016
Targeting Post-translational Modifications on Tau as a Therapeutic Strategy for Alzheimer's Disease
2011
Mutations in adenine-binding pockets enhance catalytic properties of NAD(P)H-dependent enzymes
2015 StandoutNobel
Designing Eukaryotic Gene Expression Regulation Using Machine Learning
2019
CRISPR-Based Technologies for the Manipulation of Eukaryotic Genomes
2016 Standout
Cornerstones of CRISPR–Cas in drug discovery and therapy
2016 StandoutNobel
Catalytic efficiencies of directly evolved phosphotriesterase variants with structurally different organophosphorus compounds in vitro
2015 StandoutNobel
Machine learning-guided co-optimization of fitness and diversity facilitates combinatorial library design in enzyme engineering
2024
Engineering specialized metabolic pathways—is there a room for enzyme improvements?
2012
Post-translational modifications of tau protein: Implications for Alzheimer's disease
2011
Strategies for the consolidation of biologically mediated events in the conversion of pre-treated lignocellulose into ethanol
2013
A Highly Characterized Yeast Toolkit for Modular, Multipart Assembly
2015
Improving Protein Expression, Stability, and Function with ProteinMPNN
2024 StandoutNobel
Metabolic Engineering: Past and Future
2013
Structure of a designed tetrahedral protein assembly variant engineered to have improved soluble expression
2015 StandoutNobel
Overcoming an optimization plateau in the directed evolution of highly efficient nerve agent bioscavengers
2017 StandoutNobel
Corynebacterium glutamicum Metabolic Engineering with CRISPR Interference (CRISPRi)
2016
Synthetic biology for the directed evolution of protein biocatalysts: navigating sequence space intelligently
2014
Genomes in Focus: Development and Applications of CRISPR‐Cas9 Imaging Technologies
2017 StandoutNobel
High‐Throughput Screening for Terpene‐Synthase‐Cyclization Activity and Directed Evolution of a Terpene Synthase
2013 StandoutNobel
Refactoring the Silent Spectinabilin Gene Cluster Using a Plug-and-Play Scaffold
2013
Conditional Recruitment to a DNA-Bound CRISPR–Cas Complex Using a Colocalization-Dependent Protein Switch
2020 StandoutNobel
Directed evolution: Past, present, and future
2012
Opportunities and Challenges for Machine Learning-Assisted Enzyme Engineering
2024 Nobel
Lignocellulosic biomass: a sustainable platform for the production of bio-based chemicals and polymers
2015 Standout
Characteristics of seismic activity of the Upper Silesian Coal Basin in Poland
2006 Standout
New tools for reconstruction and heterologous expression of natural product biosynthetic gene clusters
2015
Identification of Mechanism-Based Inactivation in P450-Catalyzed Cyclopropanation Facilitates Engineering of Improved Enzymes
2016 StandoutNobel
The future of biologically inspired next‐generation factories for chemicals
2017
Engineering Saccharomyces cerevisiae for next generation ethanol production
2013
A general strategy to construct small molecule biosensors in eukaryotes
2015 StandoutNobel
Engineering of temperature- and light-switchable Cas9 variants
2013 StandoutNobel
Natural Products as Sources of New Drugs from 1981 to 2014
2016 Standout
Formation of a hetero[3]rotaxane by a dynamic component-swapping strategy
2014 StandoutNobel
Generating Targeted Libraries by the Combinatorial Incorporation of Synthetic Oligonucleotides During Gene Shuffling (ISOR)
2014
Engineered Biosensors from Dimeric Ligand-Binding Domains
2018 StandoutNobel
De novo design of protein logic gates
2020 StandoutScienceNobel
Improving the Efficiency of Ligand-Binding Protein Design with Molecular Dynamics Simulations
2019 StandoutNobel
Mechanism-based inhibition of an aldolase at high concentrations of its natural substrate acetaldehyde: structural insights and protective strategies
2016
Enantioselective Total Synthesis of Nigelladine A via Late-Stage C–H Oxidation Enabled by an Engineered P450 Enzyme
2017 StandoutNobel
Works of Tong Si being referenced
Protein engineering via Bayesian optimization-guided evolutionary algorithm and robotic experiments
2022
O-GlcNAcylation modulates the self-aggregation ability of the fourth microtubule-binding repeat of tau
2008
Engineering biological systems using automated biofoundries
2017
Directed evolution: an evolving and enabling synthetic biology tool
2012
Design and construction of acetyl-CoA overproducing Saccharomyces cerevisiae strains
2014
Regulatory RNA-assisted genome engineering in microorganisms
2015
Biocatalyst development by directed evolution
2012
Automated multiplex genome-scale engineering in yeast
2017
Homology-Integrated CRISPR–Cas (HI-CRISPR) System for One-Step Multigene Disruption in Saccharomyces cerevisiae
2014
Deep Mutational Scanning of an Oxygen-Independent Fluorescent Protein CreiLOV for Comprehensive Profiling of Mutational and Epistatic Effects
2023
Customized optimization of metabolic pathways by combinatorial transcriptional engineering
2012
Direct Conversion of Xylan to Ethanol by Recombinant Saccharomyces cerevisiae Strains Displaying an Engineered Minihemicellulosome
2012