Citation Impact
Citing Papers
A cyclic oligonucleotide signaling pathway in type III CRISPR-Cas systems
2017 Science
Structures of Cas9 Endonucleases Reveal RNA-Mediated Conformational Activation
2014 StandoutScienceNobel
C2c2 is a single-component programmable RNA-guided RNA-targeting CRISPR effector
2016 StandoutScience
Structures of a CRISPR-Cas9 R-loop complex primed for DNA cleavage
2016 StandoutScienceNobel
Nucleic acid detection with CRISPR-Cas13a/C2c2
2017 StandoutScience
The Human SepSecS-tRNA Sec Complex Reveals the Mechanism of Selenocysteine Formation
2009 StandoutScienceNobel
CRISPR-Cas12a target binding unleashes indiscriminate single-stranded DNase activity
2018 StandoutScienceNobel
Incorporation of sensing modalities into de novo designed fluorescence-activating proteins
2021 StandoutNobel
Inhibition of CRISPR-Cas9 ribonucleoprotein complex assembly by anti-CRISPR AcrIIC2
2019 StandoutNobel
Guide-bound structures of an RNA-targeting A-cleaving CRISPR–Cas13a enzyme
2017 StandoutNobel
The promise and challenge of therapeutic genome editing
2020 StandoutNatureNobel
The Structural Basis for mRNA Recognition and Cleavage by the Ribosome-Dependent Endonuclease RelE
2009 StandoutNobel
A type III-B CRISPR-Cas effector complex mediating massive target DNA destruction
2016
Multiple nucleic acid cleavage modes in divergent type III CRISPR systems
2016
Working Supramolecular Machines Trapped in Glass and Mounted on a Film Surface
2001 StandoutNobel
CRISPR-Based Technologies: Impact of RNA-Targeting Systems
2018
Structural Model of a CRISPR RNA-Silencing Complex Reveals the RNA-Target Cleavage Activity in Cmr4
2014
Cpf1 Is a Single RNA-Guided Endonuclease of a Class 2 CRISPR-Cas System
2015 Standout
From one amino acid to another: tRNA-dependent amino acid biosynthesis
2008
Type III CRISPR-Cas Immunity: Major Differences Brushed Aside
2016
Molecular determinants for CRISPR RNA maturation in the Cas10–Csm complex and roles for non-Cas nucleases
2016
Efficient CRISPR-Mediated Post-Transcriptional Gene Silencing in a Hyperthermophilic Archaeon Using Multiplexed crRNA Expression
2016
MODOMICS: a database of RNA modification pathways—2013 update
2012
Structure Studies of the CRISPR-Csm Complex Reveal Mechanism of Co-transcriptional Interference
2018
Target preference of Type III-A CRISPR-Cas complexes at the transcription bubble
2019 StandoutNobel
Cmr1 enables efficient RNA and DNA interference of a III-B CRISPR–Cas system by binding to target RNA and crRNA
2017
A New Protein-Protein Interaction Sensor Based on Tripartite Split-GFP Association
2013
DNA Targeting by a Minimal CRISPR RNA-Guided Cascade
2016 StandoutNobel
Target RNA capture and cleavage by the Cmr type III-B CRISPR–Cas effector complex
2014
Bipartite recognition of target RNAs activates DNA cleavage by the Type III-B CRISPR–Cas system
2016
Spatiotemporal Control of Type III-A CRISPR-Cas Immunity: Coupling DNA Degradation with the Target RNA Recognition
2016
Cmr4 is the slicer in the RNA-targeting Cmr CRISPR complex
2014
Structure Reveals Mechanisms of Viral Suppressors that Intercept a CRISPR RNA-Guided Surveillance Complex
2017
Diversity and evolution of class 2 CRISPR–Cas systems
2017
Foreign DNA capture during CRISPR–Cas adaptive immunity
2015 StandoutNatureNobel
Structure of the CRISPR Interference Complex CSM Reveals Key Similarities with Cascade
2013
Structure and RNA-binding properties of the Type III-A CRISPR-associated protein Csm3
2013
Dynamic RNA Modifications in Gene Expression Regulation
2017 Standout
The CRISPR-associated DNA-cleaving enzyme Cpf1 also processes precursor CRISPR RNA
2016 StandoutNatureNobel
RNA and DNA Targeting by a Reconstituted Thermus thermophilus Type III-A CRISPR-Cas System
2017 StandoutNobel
A Broad-Spectrum Inhibitor of CRISPR-Cas9
2017 StandoutNobel
Programmable RNA recognition and cleavage by CRISPR/Cas9
2014 StandoutNatureNobel
Unravelling the structural and mechanistic basis of CRISPR–Cas systems
2014
DNA and RNA interference mechanisms by CRISPR-Cas surveillance complexes
2015 StandoutNobel
Expanding Role of the Jumonji C Domain as an RNA Hydroxylase
2010
Type III-A CRISPR-Cas Csm Complexes: Assembly, Periodic RNA Cleavage, DNase Activity Regulation, and Autoimmunity
2018
A Nucleophile Activation Dyad in Ribonucleases
2002
Regulation of cyclic oligoadenylate synthesis by the Staphylococcus epidermidis Cas10-Csm complex
2019
Conformational control of DNA target cleavage by CRISPR–Cas9
2015 StandoutNatureNobel
Crystal structure of archaeal toxin-antitoxin RelE–RelB complex with implications for toxin activity and antitoxin effects
2005
Cryo-EM Structures Reveal Mechanism and Inhibition of DNA Targeting by a CRISPR-Cas Surveillance Complex
2017
Second Messenger cA4 Formation within the Composite Csm1 Palm Pocket of Type III-A CRISPR-Cas Csm Complex and Its Release Path
2019
A thermostable Cas9 with increased lifetime in human plasma
2017 StandoutNobel
Annotation and Classification of CRISPR-Cas Systems
2015
RNA-activated DNA cleavage by the Type III-B CRISPR–Cas effector complex
2016
Biology and Applications of CRISPR Systems: Harnessing Nature’s Toolbox for Genome Engineering
2016 StandoutNobel
Integrase-mediated spacer acquisition during CRISPR–Cas adaptive immunity
2015 StandoutNatureNobel
Structure and Activity of the RNA-Targeting Type III-B CRISPR-Cas Complex of Thermus thermophilus
2013 StandoutNobel
Chemistry of Class 1 CRISPR-Cas effectors: Binding, editing, and regulation
2020 StandoutNobel
The Biology of CRISPR-Cas: Backward and Forward
2018 StandoutNobel
Structural insights into RNA-dependent eukaryal and archaeal selenocysteine formation
2007
A Conserved Structural Chassis for Mounting Versatile CRISPR RNA-Guided Immune Responses
2015
CasX enzymes comprise a distinct family of RNA-guided genome editors
2019 StandoutNatureNobel
Type III CRISPR-Cas systems: when DNA cleavage just isn’t enough
2017
Structural Insights into the Second Step of RNA-dependent Cysteine Biosynthesis in Archaea: Crystal Structure of Sep-tRNA:Cys-tRNA Synthase from Archaeoglobus fulgidus
2007
Two distinct RNase activities of CRISPR-C2c2 enable guide-RNA processing and RNA detection
2016 StandoutNatureNobel
Surveillance and Processing of Foreign DNA by the Escherichia coli CRISPR-Cas System
2015 StandoutNobel
Real-time observation of DNA recognition and rejection by the RNA-guided endonuclease Cas9
2016 StandoutNobel
Small RNAs are modified with N-glycans and displayed on the surface of living cells
2021 StandoutNobel
Type III CRISPR–Cas systems produce cyclic oligoadenylate second messengers
2017 Nature
Diverse evolutionary roots and mechanistic variations of the CRISPR-Cas systems
2016 Science
Multiplexed and portable nucleic acid detection platform with Cas13, Cas12a, and Csm6
2018 StandoutScience
Systematic discovery of natural CRISPR-Cas12a inhibitors
2018 StandoutScienceNobel
Genomes in Focus: Development and Applications of CRISPR‐Cas9 Imaging Technologies
2017 StandoutNobel
Structures of the CRISPR-Cmr complex reveal mode of RNA target positioning
2015 StandoutScienceNobel
The new frontier of genome engineering with CRISPR-Cas9
2014 StandoutScienceNobel
Conceptual Density Functional Theory
2003 Standout
Targeted nucleotide editing using hybrid prokaryotic and vertebrate adaptive immune systems
2016 StandoutScience
CRISPR-CasΦ from huge phages is a hypercompact genome editor
2020 StandoutScienceNobel
CasA mediates Cas3-catalyzed target degradation during CRISPR RNA-guided interference
2014 StandoutNobel
The ribonuclease activity of Csm6 is required for anti-plasmid immunity by Type III-A CRISPR-Cas systems
2018
Programmed DNA destruction by miniature CRISPR-Cas14 enzymes
2018 StandoutScienceNobel
Rational design of a split-Cas9 enzyme complex
2015 StandoutNobel
A Type III-B Cmr effector complex catalyzes the synthesis of cyclic oligoadenylate second messengers by cooperative substrate binding
2018
Artificial Molecular Machines
2000 StandoutNobel
A seed motif for target RNA capture enables efficient immune defence by a type III-B CRISPR-Cas system
2019
Regulation of the RNA and DNA nuclease activities required for Pyrococcus furiosus Type III-B CRISPR–Cas immunity
2020
RTM-Bilder einzelner Porphyrinmoleküle auf Cu(100)- und Cu(111)-Oberflächen
1999
Hydroxylation of the eukaryotic ribosomal decoding center affects translational accuracy
2014 StandoutNobel
Engineering of temperature- and light-switchable Cas9 variants
2013 StandoutNobel
Works of Tomoyuki Numata being referenced
Structural Basis of RNA-Dependent Recruitment of Glutamine to the Genetic Code
2006 Science
Crystal Structure of the Cmr2–Cmr3 Subcomplex in the CRISPR–Cas RNA Silencing Effector Complex
2013
Structural Basis for Sulfur Relay to RNA Mediated by Heterohexameric TusBCD Complex
2006
Crystal Structure of the CRISPR-Cas RNA Silencing Cmr Complex Bound to a Target Analog
2015
Crystal structure of the ribonuclease P protein Ph1877p from hyperthermophilic archaeon Pyrococcus horikoshii OT3
2004
Crystallization and preliminary X-ray diffraction analysis of the CRISPR–Cas RNA-silencing Cmr complex
2015
Contribution of Gln9 and Phe80 to Substrate Binding in Ribonuclease MCI from Bitter Gourd Seeds
2001
Agmatine-conjugated cytidine in a tRNA anticodon is essential for AUA decoding in archaea
2010
Crystal Structure of the Csm3–Csm4 Subcomplex in the Type III-A CRISPR–Cas Interference Complex
2014
Structural transformations of the Si(111)2 × 2-In surface induced by STM tip and thermal annealing
1997