Standout Papers
Citation Impact
Citing Papers
Histone demethylase KDM6A directly senses oxygen to control chromatin and cell fate
2019 StandoutScienceNobel
RIP3, an Energy Metabolism Regulator That Switches TNF-Induced Cell Death from Apoptosis to Necrosis
2009 StandoutScience
CTLA-4 Control over Foxp3 + Regulatory T Cell Function
2008 StandoutScienceNobel
CCR7 is required for the in vivo function of CD4+ CD25+ regulatory T cells
2007
Control of Regulatory T Cell Development by the Transcription Factor Foxp3
2003 StandoutScienceNobel
A noninflammatory mRNA vaccine for treatment of experimental autoimmune encephalomyelitis
2021 StandoutScienceNobel
Commensal Bifidobacterium promotes antitumor immunity and facilitates anti–PD-L1 efficacy
2015 StandoutScience
Trained immunity: A program of innate immune memory in health and disease
2016 StandoutScience
Homeostatic maintenance of natural Foxp3 + CD25+ CD4+ regulatory T cells by interleukin (IL)-2 and induction of autoimmune disease by IL-2 neutralization
2005 StandoutNobel
Construction of self-recognizing regulatory T cells from conventional T cells by controlling CTLA-4 and IL-2 expression
2013 StandoutNobel
PD-1 + regulatory T cells amplified by PD-1 blockade promote hyperprogression of cancer
2019 StandoutNobel
Aire-Dependent Thymic Development of Tumor-Associated Regulatory T Cells
2013 StandoutScienceNobel
CD4+ Tregs and immune control
2004 StandoutNobel
Arrestin 3 Mediates Endocytosis of CCR7 following Ligation of CCL19 but Not CCL21
2008
Platelet factor 4–induced T H 1-T reg polarization suppresses antitumor immunity
2024 StandoutScienceNobel
Priming of naive T cells inside tumors leads to eradication of established tumors
2004
Claudins 6, 9, and 13 are developmentally expressed renal tight junction proteins
2006
CCR7 and its ligands: balancing immunity and tolerance
2008
Nucleotides released by apoptotic cells act as a find-me signal to promote phagocytic clearance
2009 StandoutNature
Enhancement of barrier function by overexpression of claudin-4 in tight junctions of submandibular gland cells
2008
Role of C-C chemokine receptor type 7 and its ligands during neuroinflammation
2012
Regulatory T cells exert checks and balances on self tolerance and autoimmunity
2009 StandoutNobel
AKT/PKB Signaling: Navigating Downstream
2007 Standout
Unravelling the pathogenesis of inflammatory bowel disease
2007 StandoutNature
The role of the transcription factor Foxp3 in the development of regulatory T cells
2006
Autophagy in thymic epithelium shapes the T-cell repertoire and is essential for tolerance
2008 Nature
CD4+CD25+ regulatory T cells control Leishmania major persistence and immunity
2002 StandoutNature
Regulatory T Cells
2000 StandoutNobel
An endogenous tumour-promoting ligand of the human aryl hydrocarbon receptor
2011 StandoutNature
Shared Principles in NF-κB Signaling
2008 Standout
Acquisition of a Functional T Cell Receptor during T Lymphocyte Development Is Enforced by HEB and E2A Transcription Factors
2007
Regulation of naive T cell function by the NF-κB2 pathway
2006
Central tolerance: learning self-control in the thymus
2005
Lymphocyte egress from thymus and peripheral lymphoid organs is dependent on S1P receptor 1
2004 StandoutNature
Regulatory T Cells and Immune Tolerance
2008 StandoutNobel
The zinc finger protein cKrox directs CD4 lineage differentiation during intrathymic T cell positive selection
2005
T lineage progenitors: the earliest steps en route to T lymphocytes
2006
Signaling by intrathymic cytokines, not T cell antigen receptors, specifies CD8 lineage choice and promotes the differentiation of cytotoxic-lineage T cells
2010 Standout
Autophagy: Renovation of Cells and Tissues
2011 Standout
Immunogenicity of induced pluripotent stem cells
2011 StandoutNature
Foxp3+CD25+CD4+ natural regulatory T cells in dominant self‐tolerance and autoimmune disease
2006 StandoutNobel
NF-κB and the immune response
2006
Altered thymic T-cell selection due to a mutation of the ZAP-70 gene causes autoimmune arthritis in mice
2003 StandoutNatureNobel
Translational research in immunology: Japanese perspectives
2004
CD4-CD8 Lineage Commitment Is Regulated by a Silencer Element at the ThPOK Transcription-Factor Locus
2008
Modulation of Aire regulates the expression of tissue-restricted antigens
2007
Use of RNA Interference-mediated Gene Silencing and Adenoviral Overexpression to Elucidate the Roles of AKT/Protein Kinase B Isoforms in Insulin Actions
2003
Origin and T Cell Receptor Diversity of Foxp3+CD4+CD25+ T Cells
2006
Promoter analysis of TCDD-inducible genes in a thymic epithelial cell line indicates the potential for cell-specific transcription factor crosstalk in the AhR response
2008
Primary, Adaptive, and Acquired Resistance to Cancer Immunotherapy
2017 Standout
Control of TH17/Treg Balance by Hypoxia-Inducible Factor 1
2011 StandoutNobel
Innate immunity of the newborn: basic mechanisms and clinical correlates
2007 Standout
Repertoires of Autophagy in the Pathogenesis of Ocular Diseases
2015 Standout
Chromatin as an oxygen sensor and active player in the hypoxia response
2011
Structure, regulation and function of PKB/AKT—a major therapeutic target
2003
Autophagy in immunity and inflammation
2011 StandoutNature
Aire regulates negative selection of organ-specific T cells
2003
Claudin-10 exists in six alternatively spliced isoforms that exhibit distinct localization and function
2009
Naturally Arising CD4+Regulatory T Cells for Immunologic Self -Tolerance and Negative Control of Immune Responses
2003 StandoutNobel
Rapid induction of medullary thymocyte phenotypic maturation and egress inhibition by nanomolar sphingosine 1-phosphate receptor agonist
2003
Characterization of the thymic IL-7 niche in vivo
2009
Sialyl Lewis x (CD15s) identifies highly differentiated and most suppressive FOXP3 high regulatory T cells in humans
2015 StandoutNobel
CD4+CD25−LAG3+regulatory T cells controlled by the transcription factor Egr-2
2009 StandoutNobel
Aire
2009
Immunologic Self-Tolerance Maintained by Cd25+Cd4+Regulatory T Cells Constitutively Expressing Cytotoxic T Lymphocyte–Associated Antigen 4
2000 StandoutNobel
Dependence of Self-Tolerance on TRAF6-Directed Development of Thymic Stroma
2005 Science
Developmental regulation of Foxp3 expression during ontogeny
2005
Expression of mucosal chemokines TECK/CCL25 and MEC/CCL28 during fetal development of the ovine mucosal immune system
2007
Synergism of Cytotoxic T Lymphocyte–Associated Antigen 4 Blockade and Depletion of Cd25+ Regulatory T Cells in Antitumor Therapy Reveals Alternative Pathways for Suppression of Autoreactive Cytotoxic T Lymphocyte Responses
2001 StandoutNobel
Orphan Nuclear Receptor Nur77 Is Involved in Caspase-independent Macrophage Cell Death
2003
Foxp3+natural regulatory T cells preferentially form aggregates on dendritic cellsin vitroand actively inhibit their maturation
2008 StandoutNobel
CCR7 Directs the Migration of Thymocytes into the Thymic Medulla
2004
Msx2-interacting nuclear target protein (Mint) deficiency reveals negative regulation of early thymocyte differentiation by Notch/RBP-J signaling
2007 StandoutNobel
Conditional stability of T cells
2010 StandoutNatureNobel
Critical Role for CXCR4 Signaling in Progenitor Localization and T Cell Differentiation in the Postnatal Thymus
2003
Proenkephalin+regulatory T cells expanded by ultraviolet B exposure maintain skin homeostasis with a healing function
2020 StandoutNobel
Epigenetic conversion of conventional T cells into regulatory T cells by CD28 signal deprivation
2020 StandoutNobel
Anti-CCR4 mAb selectively depletes effector-type FoxP3+CD4+regulatory T cells, evoking antitumor immune responses in humans
2013 StandoutNobel
Detection of an autoreactive T-cell population within the polyclonal repertoire that undergoes distinct autoimmune regulator (Aire)-mediated selection
2012
Aryl hydrocarbon receptor negatively regulates dendritic cell immunogenicity via a kynurenine-dependent mechanism
2010
Claudins and the Modulation of Tight Junction Permeability
2013 Standout
Immunotherapy: Bewitched, Bothered, and Bewildered No More
2004 StandoutScienceNobel
The role of intestinal bifidobacteria on immune system development in young rats
2010
Selective engagement of G protein coupled receptor kinases (GRKs) encodes distinct functions of biased ligands
2009 StandoutNobel
Aire-dependent production of XCL1 mediates medullary accumulation of thymic dendritic cells and contributes to regulatory T cell development
2011
A distinct subpopulation of CD25−T-follicular regulatory cells localizes in the germinal centers
2017 StandoutNobel
Autophagy in Health and Disease: A Double-Edged Sword
2004 StandoutScience
Works of Tomoo Ueno being referenced
The Lymphotoxin Pathway Regulates Aire-Independent Expression of Ectopic Genes and Chemokines in Thymic Stromal Cells
2008
Controlling the thymic microenvironment
2005
CCR7-Dependent Cortex-to-Medulla Migration of Positively Selected Thymocytes Is Essential for Establishing Central Tolerance
2006
Role for CCR7 Ligands in the Emigration of Newly Generated T Lymphocytes from the Neonatal Thymus
2002
Expression patterns of claudin family of tight junction membrane proteins in developing mouse submandibular gland
2004
Akt Inhibits the Orphan Nuclear Receptor Nur77 and T-cell Apoptosis
2001
The role of CCL21 in recruitment of T-precursor cells to fetal thymi
2004
Developmental kinetics, turnover, and stimulatory capacity of thymic epithelial cells
2006
NF-κB-Inducing Kinase Establishes Self-Tolerance in a Thymic Stroma-Dependent Manner
2004 StandoutNobel
A Unique Thymic Fibroblast Population Revealed by the Monoclonal Antibody MTS-15
2007
Keratinocyte growth factor (KGF) enhances postnatal T-cell development via enhancements in proliferation and function of thymic epithelial cells
2007
T Cell-Specific Disruption of Arylhydrocarbon Receptor Nuclear Translocator (Arnt) Gene Causes Resistance to 2,3,7,8-Tetrachlorodibenzo-p-dioxin-Induced Thymic Involution
2003
CCR7 Signals Are Essential for Cortex–Medulla Migration of Developing Thymocytes
2004
In Vivo Treatment of Class II MHC-Deficient Mice with Anti-TCR Antibody Restores the Generation of Circulating CD4 T Cells and Optimal Architecture of Thymic Medulla
2003