Standout Papers
Citation Impact
Citing Papers
Assembly of a Functional HCV Glycoprotein Heterodimer
2007
Production of infectious genotype 1a hepatitis C virus (Hutchinson strain) in cultured human hepatoma cells
2006
Cell culture-grown hepatitis C virus is infectious in vivo and can be recultured in vitro
2006 StandoutNobel
Construction and characterization of infectious intragenotypic and intergenotypic hepatitis C virus chimeras
2006
Compensatory Mutations in E1, p7, NS2, and NS3 Enhance Yields of Cell Culture-Infectious Intergenotypic Chimeric Hepatitis C Virus
2006
Insertion of Green Fluorescent Protein into Nonstructural Protein 5A Allows Direct Visualization of Functional Hepatitis C Virus Replication Complexes
2004 StandoutNobel
Robust hepatitis C virus infection in vitro
2005
Roles for endocytic trafficking and phosphatidylinositol 4-kinase III alpha in hepatitis C virus replication
2009
Complete Replication of Hepatitis C Virus in Cell Culture
2005 StandoutScienceNobel
Plasmacytoid dendritic cells initiate a complex chemokine and cytokine network and are a viable drug target in chronic HCV patients
2007 StandoutNobel
Superinfection Exclusion in Cells Infected with Hepatitis C Virus
2007 StandoutNobel
Evidence for a functional RNA element in the hepatitis C virus core gene
2007 StandoutNobel
Mouse models of acute and chronic hepacivirus infection
2017 StandoutScienceNobel
Persistent Hepatitis C Virus Infection In Vitro: Coevolution of Virus andHost
2006
Production of Infectious Genotype 1b Virus Particles in Cell Culture and Impairment by Replication Enhancing Mutations
2009
NS2 Protein of Hepatitis C Virus Interacts with Structural and Non-Structural Proteins towards Virus Assembly
2011
Current progress in development of hepatitis C virus vaccines
2013
Replication of a hepatitis C virus replicon clone in mouse cells.
2006
Evidence for the Formation of a Heptameric Ion Channel Complex by the Hepatitis C Virus P7 Protein in Vitro
2006
Viral and Cellular Determinants of the Hepatitis C Virus Envelope-Heparan SulfateInteraction
2006
Identification and Targeting of an Interaction between a Tyrosine Motif within Hepatitis C Virus Core Protein and AP2M1 Essential for Viral Assembly
2012
An updated analysis of hepatitis C virus genotypes and subtypes based on the complete coding region
2011
Characterization of Hepatitis C Virus Particle Subpopulations Reveals Multiple Usage of the Scavenger Receptor BI for Entry Steps
2012
MAP-Kinase Regulated Cytosolic Phospholipase A2 Activity Is Essential for Production of Infectious Hepatitis C Virus Particles
2012
Early steps of the hepatitis C virus life cycle
2008
Assembly of infectious hepatitis C virus particles
2010
Cell Culture Systems for Hepatitis C Virus
2013
Intracellular Proton Conductance of the Hepatitis C Virus p7 Protein and Its Contribution to Infectious Virus Production
2010
SEC14L2 enables pan-genotype HCV replication in cell culture
2015 StandoutNatureNobel
Development of novel therapies for hepatitis C
2010
Identification and characterization of a natural inter-genotypic (2b/1b) recombinant hepatitis C virus in Japan
2011
A peptide derived from hepatitis C virus E2 envelope protein inhibits a post-binding step in HCV entry
2010
Evaluation of ITX 5061, a Scavenger Receptor B1 Antagonist: Resistance Selection and Activity in Combination With Other Hepatitis C Virus Antivirals
2012
Completion of the entire hepatitis C virus life cycle in genetically humanized mice
2013 StandoutNatureNobel
Animal Models for the Study of Hepatitis C Virus Infection and Related Liver Disease
2012
Structural Determinants That Target the Hepatitis C Virus Core Protein to Lipid Droplets
2006
Serum amyloid A has antiviral activity against hepatitis C virus by inhibiting virus entry in a cell culture system
2006
Hepatitis C virus—host interactions, replication, and viral assembly
2012
Molecular Determinants and Dynamics of Hepatitis C Virus Secretion
2012
Treatment triumphs
2014 StandoutNatureNobel
Role of lipid metabolism in hepatitis C virus assembly and entry
2009
Direct Infection and Replication of Naturally Occurring Hepatitis C Virus Genotypes 1, 2, 3 and 4 in Normal Human Hepatocyte Cultures
2008
Anti-CD81 antibodies can prevent a hepatitis C virus infection in vivo
2008
Unravelling hepatitis C virus replication from genome to function
2005 StandoutNatureNobel
Robust Hepatitis C Genotype 3a Cell Culture Releasing Adapted Intergenotypic 3a/2a (S52/JFH1) Viruses
2007
Hepatitis C Virus p7 is Critical for Capsid Assembly and Envelopment
2013
Architects of assembly: roles of Flaviviridae non-structural proteins in virion morphogenesis
2008 StandoutNobel
Hepatitis C virus induces interferon-λ and interferon-stimulated genes in primary liver cultures
2010 StandoutNobel
Evasion of intracellular host defence by hepatitis C virus
2005 Nature
Challenge Pools of Hepatitis C Virus Genotypes 1–6 Prototype Strains: Replication Fitness and Pathogenicity in Chimpanzees and Human Liver–Chimeric Mouse Models
2010
In Vivo Evaluation of the Cross-Genotype Neutralizing Activity of Polyclonal Antibodies Against Hepatitis C Virus Δσ
2011
Expression of paramyxovirus V proteins promotes replication and spread of hepatitis C virus in cultures of primary human fetal liver cells
2010 StandoutNobel
Hepatitis C viral protein translation: mechanisms and implications in developing antivirals
2011
Hepatitis C virus envelope glycoprotein immunization of rodents elicits cross-reactive neutralizing antibodies
2007 StandoutNobel
Hepatitis C virus comes full circle
2005
Anti-hepatitis C Virus Activity of Tamoxifen Reveals the Functional Association of Estrogen Receptor with Viral RNA Polymerase NS5B
2007
Hepatitis C Virus RNA Replication
2013
Identification of the Niemann-Pick C1–like 1 cholesterol absorption receptor as a new hepatitis C virus entry factor
2012
Hepatitis C virus entry: Molecular biology and clinical implications
2006
Cell entry of hepatitis C virus
2006
Vps4 and the ESCRT-III complex are required for the release of infectious hepatitis C virus particles
2009
Broadly neutralizing antibodies protect against hepatitis C virus quasispecies challenge
2007
Serum-derived hepatitis C virus infectivity in interferon regulatory factor-7-suppressed human primary hepatocytes
2006
Silencing of USP18 Potentiates the Antiviral Activity of Interferon Against Hepatitis C Virus Infection
2006 StandoutNobel
Identification of bisindolylmaleimides and indolocarbazoles as inhibitors of HCV replication by tube-capture-RT-PCR
2009
Highly Efficient JFH1‐Based Cell‐Culture System for Hepatitis C Virus Genotype 5a: Failure of Homologous Neutralizing‐Antibody Treatment to Control Infection
2008
Visualizing Hepatitis C Virus Infections in Human Liver by Two-Photon Microscopy
2009
Hepatitis C Virus Proteins: From Structure to Function
2013
Structural and Functional Characterization of Nonstructural Protein 2 for Its Role in Hepatitis C Virus Assembly
2008
Hepatitis C virus cell-cell transmission in hepatoma cells in the presence of neutralizing antibodies
2007
Primary Hepatocyte Culture Supports Hepatitis C Virus Replication: A Model for Infection-Associated Hepatocarcinogenesis
2010
Palmitoylation of Hepatitis C Virus Core Protein Is Important for Virion Production
2009
RNA Interference and Single Particle Tracking Analysis of Hepatitis C Virus Endocytosis
2009
The lipid droplet is an important organelle for hepatitis C virus production
2007
Scavenger receptor class B type I is a key host factor for hepatitis C virus infection required for an entry step closely linked to CD81
2007
Hepatitis C Virus p7 Protein Is Crucial for Assembly and Release of Infectious Virions
2007
The ESCRT System Is Required for Hepatitis C Virus Production
2011
Prospects for a vaccine against the hepatitis C virus
2005 StandoutNatureNobel
Apolipoprotein B–dependent hepatitis C virus secretion is inhibited by the grapefruit flavonoid naringenin
2008
Chapter 2 Cutting the Gordian Knot-Development and Biological Relevance of Hepatitis C Virus Cell Culture Systems
2008
Treating viral hepatitis C: efficacy, side effects, and complications
2006
A Human Monoclonal Antibody Targeting Scavenger Receptor Class B Type I Precludes Hepatitis C Virus Infection and Viral Spread In Vitro and In Vivo
2011 StandoutNobel
Efficient hepatitis C virus particle formation requires diacylglycerol acyltransferase-1
2010
High Density Lipoprotein Inhibits Hepatitis C Virus-neutralizing Antibodies by Stimulating Cell Entry via Activation of the Scavenger Receptor BI
2006
Mouse Hepatic Cells Support Assembly of Infectious Hepatitis C Virus Particles
2011
Cardif is an adaptor protein in the RIG-I antiviral pathway and is targeted by hepatitis C virus
2005 StandoutNature
Cell culture–produced hepatitis C virus does not infect peripheral blood mononuclear cells
2008 StandoutNobel
Hepatitis C virus versus innate and adaptive immune responses: a tale of coevolution and coexistence
2009
Antiviral strategies in hepatitis C virus infection
2012
Biochemical and Morphological Properties of Hepatitis C Virus Particles and Determination of Their Lipidome
2010
Enhancement of genotype 1 hepatitis C virus replication by bile acids through FXR
2007
Expanded classification of hepatitis C virus into 7 genotypes and 67 subtypes: Updated criteria and genotype assignment web resource
2013 StandoutNobel
Structural and mechanistic insights into hepatitis C viral translation initiation
2006 StandoutNobel
Claudin Association with CD81 Defines Hepatitis C Virus Entry
2010
The Humoral Immune Response to HCV: Understanding is Key to Vaccine Development
2014
CD81 is dispensable for hepatitis C virus cell-to-cell transmission in hepatoma cells
2008 StandoutNobel
The ins and outs of hepatitis C virus entry and assembly
2013 StandoutNobel
Regulation of Hepatitis C Virion Production via Phosphorylation of the NS5A Protein
2008
Human occludin is a hepatitis C virus entry factor required for infection of mouse cells
2009 StandoutNatureNobel
Temporal Analysis of Hepatitis C Virus Cell Entry with Occludin Directed Blocking Antibodies
2013
Trafficking of Hepatitis C Virus Core Protein during Virus Particle Assembly
2011
Mechanism of action of interferon and ribavirin in treatment of hepatitis C
2005 Nature
Role of low-density lipoprotein receptor in the hepatitis C virus life cycle
2011
Oxidized low-density lipoprotein inhibits hepatitis C virus cell entry in human hepatoma cells
2006 StandoutNobel
Genotype-dependent sensitivity of hepatitis C virus to inhibitors of the p7 ion channel
2008
Regulation of hepatitis C virus secretion by the Hrs-dependent exosomal pathway
2011
Claudin-1 is a hepatitis C virus co-receptor required for a late step in entry
2007 StandoutNatureNobel
A diverse range of gene products are effectors of the type I interferon antiviral response
2011 StandoutNatureNobel
Systematic review: anti-viral therapy of recurrent hepatitis C after liver transplantation
2010
Hepatitis C virus RNA replication is regulated by FKBP8 and Hsp90
2006
Expression of heterologous proteins flanked by NS3-4A cleavage sites within the hepatitis C virus polyprotein
2013 StandoutNobel
Development and characterization of hepatitis C virus genotype 1-7 cell culture systems: Role of CD81 and scavenger receptor class B type I and effect of antiviral drugs # †
2008
Hepatitis C Virus Entry
2007 StandoutNobel
Antiviral effects of amantadine and iminosugar derivatives against hepatitis C virus†
2007
Virion Assembly and Release
2013
The Lipid Droplet Binding Domain of Hepatitis C Virus Core Protein Is a Major Determinant for Efficient Virus Assembly
2007
Measuring HCV Infectivity Produced in Cell Culture and In Vivo
2009
Production of Infectious Hepatitis C Virus in Primary Cultures of Human Adult Hepatocytes
2010
Diacylglycerol Acyltransferase-1 Localizes Hepatitis C Virus NS5A Protein to Lipid Droplets and Enhances NS5A Interaction with the Viral Capsid Core
2013
From Structure to Function: New Insights into Hepatitis C Virus RNA Replication
2005
A reporter cell line for rapid and sensitive evaluation of hepatitis C virus infectivity and replication
2009
The Exchangeable Apolipoprotein ApoC-I Promotes Membrane Fusion of Hepatitis C Virus
2007
Genomic Analysis Reveals a Potential Role for Cell Cycle Perturbation in HCV-Mediated Apoptosis of Cultured Hepatocytes
2009 StandoutNobel
Inhibition of hepatitis C virus p7 membrane channels in a liposome-based assay system
2007
Animal Models for Hepatitis C
2013
A natural inter-genotypic (2b/1b) recombinant of hepatitis C virus in the Philippines
2006
The HCV Life Cycle: In vitro Tissue Culture Systems and Therapeutic Targets
2014 Standout
Hepatitis C virus receptors claudin-1 and occludin after liver transplantation and influence on early viral kinetics
2010
Hepatitis C virus receptor expression in normal and diseased liver tissue
2007
Hepatitis C Virus Glycoproteins Mediate Low pH-dependent Membrane Fusion with Liposomes
2005
Understanding the hepatitis C virus life cycle paves the way for highly effective therapies
2013 StandoutNobel
A Hepatitis C Virus (HCV) Vaccine Comprising Envelope Glycoproteins gpE1/gpE2 Derived from a Single Isolate Elicits Broad Cross-Genotype Neutralizing Antibodies in Humans
2013 StandoutNobel
Hepatitis C virus: why do we need a vaccine to prevent a curable persistent infection?
2015
A genetically humanized mouse model for hepatitis C virus infection
2011 StandoutNatureNobel
Recombinant HCV Variants With NS5A From Genotypes 1–7 Have Different Sensitivities to an NS5A Inhibitor but Not Interferon-α
2010
HCV Replicons: Overview and Basic Protocols
2009
Secretion of Hepatitis C Virus Envelope Glycoproteins Depends on Assembly of Apolipoprotein B Positive Lipoproteins
2009
Scavenger receptor class B type I and the hypervariable region-1 of hepatitis C virus in cell entry and neutralisation
2011
Novel Insights into Hepatitis C Virus Replication and Persistence
2004
The human liver-uPA-SCID mouse: A model for the evaluation of antiviral compounds against HBV and HCV
2008
Activity-based Protein Profiling Identifies a Host Enzyme, Carboxylesterase 1, Which Is Differentially Active during Hepatitis C Virus Replication
2010
Hepatitis C Virus Replication in Transfected and Serum-Infected Cultured Human Fetal Hepatocytes
2007
Innate Immune Responses to Hepatitis C Virus
2013 StandoutNobel
Structural and Functional Studies of Nonstructural Protein 2 of the Hepatitis C Virus Reveal Its Key Role as Organizer of Virion Assembly
2010
25 years of interferon-based treatment of chronic hepatitis C: an epoch coming to an end
2013
Novel human SR-BI antibodies prevent infection and dissemination of HCV in vitro and in humanized mice
2012
Three-Dimensional Architecture and Biogenesis of Membrane Structures Associated with Hepatitis C Virus Replication
2012
HCV and the hepatic lipid pathway as a potential treatment target
2011
Essential Role of Domain III of Nonstructural Protein 5A for Hepatitis C Virus Infectious Particle Assembly
2008
Development of Virus-Like Particle Technology from Small Highly Symmetric to Large Complex Virus-Like Particle Structures
2013 Standout
Replication of hepatitis C virus
2007 StandoutNobel
The non‐immunosuppressive cyclosporin DEBIO‐025 is a potent inhibitor of hepatitis C virus replication in vitro†
2006
Quantitative Analysis of the Hepatitis C Virus Replication Complex
2005
Regulation of the Production of Infectious Genotype 1a Hepatitis C Virus by NS5A Domain III
2011
Serology-Enabled Discovery of Genetically Diverse Hepaciviruses in a New Host
2012 StandoutNobel
Lipoprotein profiles in SCID/uPA mice transplanted with human hepatocytes become human-like and correlate with HCV infection success
2010
Human combinatorial libraries yield rare antibodies that broadly neutralize hepatitis C virus
2007
Replication of Hepatitis C Virus (HCV) RNA in Mouse Embryonic Fibroblasts: Protein Kinase R (PKR)-Dependent and PKR-Independent Mechanisms for Controlling HCV RNA Replication and Mediating Interferon Activities
2006
Viral and therapeutic control of IFN-β promoter stimulator 1 during hepatitis C virus infection
2006
Role of the Hepatitis C Virus Core+1 Open Reading Frame and Corecis-Acting RNA Elements in Viral RNA Translation and Replication
2008
Advantages of a single-cycle production assay to study cell culture-adaptive mutations of hepatitis C virus
2008
The low-density lipoprotein receptor plays a role in the infection of primary human hepatocytes by hepatitis C virus
2006
Characterization of the Envelope Glycoproteins Associated with Infectious Hepatitis C Virus
2010
Sulfated Homologues of Heparin Inhibit Hepatitis C Virus Entry into Mammalian Cells
2007
Unbiased probing of the entire hepatitis C virus life cycle identifies clinical compounds that target multiple aspects of the infection
2009
Rational HIV Immunogen Design to Target Specific Germline B Cell Receptors
2013 StandoutScienceNobel
Hepatitis C Virus Entry
2013
Role of Annexin A2 in the Production of Infectious Hepatitis C Virus Particles
2010
Scavenger Receptor BI and BII Expression Levels Modulate Hepatitis C Virus Infectivity
2007
Robust full-length hepatitis C virus genotype 2a and 2b infectious cultures using mutations identified by a systematic approach applicable to patient strains
2012
Identification of New Functional Regions in Hepatitis C Virus Envelope Glycoprotein E2
2010
Claudin-6 and Claudin-9 Function as Additional Coreceptors for Hepatitis C Virus
2007
A virocidal amphipathic α-helical peptide that inhibits hepatitis C virus infection in vitro
2008
Human broadly neutralizing antibodies to the envelope glycoprotein complex of hepatitis C virus
2012 StandoutNobel
Cell Culture Adaptation of Hepatitis C Virus and In Vivo Viability of an Adapted Variant
2007
Preferential association of Hepatitis C virus with apolipoprotein B48-containing lipoproteins
2006
Protein Kinase A-Dependent Step(s) in Hepatitis C Virus Entry and Infectivity
2008
Hepatitis C virus cell entry: role of lipoproteins and cellular receptors
2009
Unique Features of Hepatitis C Virus Capsid Formation Revealed by De Novo Cell-Free Assembly
2004
Production of Infectious Hepatitis C Virus by Well-Differentiated, Growth-Arrested Human Hepatoma-Derived Cells
2006
Isolation and Characterization of Broadly Neutralizing Human Monoclonal Antibodies to the E1 Glycoprotein of Hepatitis C Virus
2007
Efficient Replication of Genotype 3a and 4a Hepatitis C Virus Replicons in Human Hepatoma Cells
2012 StandoutNobel
Development of JFH1-based cell culture systems for hepatitis C virus genotype 4a and evidence for cross-genotype neutralization
2008
Hepatitis C Virus Core Protein Is a Dimeric Alpha-Helical Protein Exhibiting Membrane Protein Features
2005
Signal Peptide Cleavage and Internal Targeting Signals Direct the Hepatitis C Virus p7 Protein to Distinct Intracellular Membranes
2005
High-Avidity Monoclonal Antibodies against the Human Scavenger Class B Type I Receptor Efficiently Block Hepatitis C Virus Infection in the Presence of High-Density Lipoprotein
2007 StandoutNobel
Identification of transferrin receptor 1 as a hepatitis C virus entry factor
2013
High-density lipoproteins reduce the neutralizing effect of hepatitis C virus (HCV)-infected patient antibodies by promoting HCV entry
2006
Disrupting the association of hepatitis C virus core protein with lipid droplets correlates with a loss in production of infectious virus
2007
Initiation of Hepatitis C Virus Infection Is Dependent on Cholesterol and Cooperativity between CD81 and Scavenger Receptor B Type I
2006
Rapid induction of virus-neutralizing antibodies and viral clearance in a single-source outbreak of hepatitis C
2007
Development of an Intergenotypic Hepatitis C Virus (HCV) Cell Culture Method To Assess Antiviral Susceptibilities and Resistance Development of HCV NS3 Protease Genes from HCV Genotypes 1 to 6
2010
The NS5A Protein of Bovine Viral Diarrhea Virus Contains an Essential Zinc-Binding Site Similar to That of the Hepatitis C Virus NS5A Protein
2006 StandoutNobel
Human serum leads to differentiation of human hepatoma cells, restoration of very-low-density lipoprotein secretion, and a 1000-fold increase in HCV Japanese fulminant hepatitis type 1 titers
2013 StandoutNobel
Hepatitis C Virus Entry Depends on Clathrin-Mediated Endocytosis
2006
Viral entry and escape from antibody-mediated neutralization influence hepatitis C virus reinfection in liver transplantation
2010
Modeling shows that the NS5A inhibitor daclatasvir has two modes of action and yields a shorter estimate of the hepatitis C virus half-life
2013
Hepatitis C virus entry: potential receptors and their biological functions
2006
Neutralizing Antibody-Resistant Hepatitis C Virus Cell-to-Cell Transmission
2010
Hepatitis C Virus NS2 Protein Contributes to Virus Particle Assembly via Opposing Epistatic Interactions with the E1-E2 Glycoprotein and NS3-NS4A Enzyme Complexes
2009
Genetic diversity and evolution of hepatitis C virus – 15 years on
2004
Hepatitis C Virus p7 and NS2 Proteins Are Essential for Production of Infectious Virus
2007 StandoutNobel
Identification of Residues Required for RNA Replication in Domains II and III of the Hepatitis C Virus NS5A Protein
2007 StandoutNobel
Hepatoma Cell Density Promotes Claudin-1 and Scavenger Receptor BI Expression and Hepatitis C Virus Internalization
2009
Human Serum Amyloid A Protein Inhibits Hepatitis C Virus Entry into Cells
2007
Identification of Rodent Homologs of Hepatitis C Virus and Pegiviruses
2013 StandoutNobel
A Genetic Interaction between the Core and NS3 Proteins of Hepatitis C Virus Is Essential for Production of Infectious Virus
2011
MicroRNA-122 antagonism against hepatitis C virus genotypes 1–6 and reduced efficacy by host RNA insertion or mutations in the HCV 5′ UTR
2011
The α Isoform of Protein Kinase CKI Is Responsible for Hepatitis C Virus NS5A Hyperphosphorylation
2006
CD81 Is a Central Regulator of Cellular Events Required for Hepatitis C Virus Infection of Human Hepatocytes
2008
Modulation of Hepatitis C Virus RNA Abundance by a Liver-Specific MicroRNA
2005 StandoutScience
Cellular cofactors affecting hepatitis C virus infection and replication
2007 StandoutNobel
Pharmacokinetics and Safety in Cynomolgus Monkeys of a Monoclonal Antibody Targeting Human Scavenger Receptor Class B Type-1 for Hepatitis C Treatment
2013
Development of a Cell-Based Hepatitis C Virus Infection Fluorescent Resonance Energy Transfer Assay for High-Throughput Antiviral Compound Screening
2009
Oligomerization of Hepatitis C Virus Core Protein Is Crucial for Interaction with the Cytoplasmic Domain of E1 Envelope Protein
2006
Cyclophilin A Is an Essential Cofactor for Hepatitis C Virus Infection and the Principal Mediator of Cyclosporine Resistance In Vitro
2008
3′ RNA Elements in Hepatitis C Virus Replication: Kissing Partners and Long Poly(U)
2007 StandoutNobel
Characterization of the Early Steps of Hepatitis C Virus Infection by Using Luciferase Reporter Viruses
2006
Highly efficient full-length hepatitis C virus genotype 1 (strain TN) infectious culture system
2012
A cell protection screen reveals potent inhibitors of multiple stages of the hepatitis C virus life cycle
2010 StandoutNobel
Replication of Subgenomic Hepatitis C Virus Replicons in Mouse Fibroblasts Is Facilitated by Deletion of Interferon Regulatory Factor 3 and Expression of Liver-Specific MicroRNA 122
2010
Neutralizing Antibody Response to Hepatitis C Virus
2011
Time- and Temperature-Dependent Activation of Hepatitis C Virus for Low-pH-Triggered Entry
2006 StandoutNobel
Hepatitis C Virus Induces CD81 and Claudin-1 Endocytosis
2012
Human Apolipoprotein E Is Required for Infectivity and Production of Hepatitis C Virus in Cell Culture
2007
Successful anti-scavenger receptor class B type I (SR-BI) monoclonal antibody therapy in humanized mice after challenge with HCV variants with in vitro resistance to SR-BI-targeting agents
2014 StandoutNobel
The Hepatitis C Virus RNA 3′-Untranslated Region Strongly Enhances Translation Directed by the Internal Ribosome Entry Site
2006
Virus‐neutralizing antibodies to hepatitis C virus
2013
Hepatitis C Virus Hypervariable Region 1 Modulates Receptor Interactions, Conceals the CD81 Binding Site, and Protects Conserved Neutralizing Epitopes
2010
Novel Infectious cDNA Clones of Hepatitis C Virus Genotype 3a (Strain S52) and 4a (Strain ED43): Genetic Analyses and In Vivo Pathogenesis Studies
2010
Design of a hyperstable 60-subunit protein icosahedron
2016 StandoutNatureNobel
Apolipoprotein C1 Association with Hepatitis C Virus
2008
Comprehensive linker-scanning mutagenesis of the hepatitis C virus E1 and E2 envelope glycoproteins reveals new structure–function relationships
2011
Diverse CD81 Proteins Support Hepatitis C Virus Infection
2006 StandoutNobel
Hepatitis C virus production by human hepatocytes dependent on assembly and secretion of very low-density lipoproteins
2007
The Hepatitis C Virus NS4B Protein Can trans -Complement Viral RNA Replication and Modulates Production of Infectious Virus
2008
Different Domains of CD81 Mediate Distinct Stages of Hepatitis C Virus Pseudoparticle Entry
2006
Alanine Scanning of the Hepatitis C Virus Core Protein Reveals Numerous Residues Essential for Production of Infectious Virus
2007 StandoutNobel
Development of NS3/4A Protease-Based Reporter Assay Suitable for Efficiently Assessing Hepatitis C Virus Infection
2009
NS3 Helicase Domains Involved in Infectious Intracellular Hepatitis C Virus Particle Assembly
2008
Identification of a Residue in Hepatitis C Virus E2 Glycoprotein That Determines Scavenger Receptor BI and CD81 Receptor Dependency and Sensitivity to Neutralizing Antibodies
2008
Ultrastructural and Biophysical Characterization of Hepatitis C Virus Particles Produced in Cell Culture
2010
Identification of Conserved Residues in the E2 Envelope Glycoprotein of the Hepatitis C Virus That Are Critical for CD81 Binding
2006
The Level of CD81 Cell Surface Expression Is a Key Determinant for Productive Entry of Hepatitis C Virus into Host Cells
2006
Depletion of interfering antibodies in chronic hepatitis C patients and vaccinated chimpanzees reveals broad cross-genotype neutralizing activity
2009
De novo infection and propagation of wild-type Hepatitis C virus in human T lymphocytes in vitro
2006
Differential Biophysical Properties of Infectious Intracellular and Secreted Hepatitis C Virus Particles
2006
Effect of Cell Polarization on Hepatitis C Virus Entry
2007
Hypervariable Region 1 Differentially Impacts Viability of Hepatitis C Virus Strains of Genotypes 1 to 6 and Impairs Virus Neutralization
2010
Targeting HCV Entry For Development of Therapeutics
2010
Structure of the catalytic domain of the hepatitis C virus NS2-3 protease
2006 StandoutNatureNobel
Identification of a Naturally Occurring Recombinant Genotype 2/6 Hepatitis C Virus
2006
Works of Tomoko Date being referenced
Cell culture and infection system for hepatitis C virus
2006
Replication and infectivity of a novel genotype 1b hepatitis C virus clone
2012
Production and characterization of HCV particles from serum-free culture
2011
Efficient replication of the genotype 2a hepatitis C virus subgenomic replicon
2003
Sequence analysis of hepatitis C virus isolated from a fulminant hepatitis patient*
2001
Genotype 2a Hepatitis C Virus Subgenomic Replicon Can Replicate in HepG2 and IMY-N9 Cells
2004
Biological properties of purified recombinant HCV particles with an epitope-tagged envelope
2010
The roles of CD81 and glycosaminoglycans in the adsorption and uptake of infectious HCV particles
2007
Production of infectious hepatitis C virus in tissue culture from a cloned viral genome
2005 Standout
RNA Polymerase Activity and Specific RNA Structure Are Required for Efficient HCV Replication in Cultured Cells
2010
Replication of Hepatitis C Virus Genotype 3a in Cultured Cells
2012
In vivo adaptation of hepatitis C virus in chimpanzees for efficient virus production and evasion of apoptosis
2011
Neutralizing Antibodies Induced by Cell Culture–Derived Hepatitis C Virus Protect Against Infection in Mice
2013
Comparison between Subgenomic Replicons of Hepatitis C Virus Genotypes 2a (JFH-1) and 1b (Con1 NK5.1)
2005
Processing of hepatitis C virus core protein is regulated by its C‐terminal sequence
2003
The NS3 Helicase and NS5B-to-3′X Regions Are Important for Efficient Hepatitis C Virus Strain JFH-1 Replication in Huh7 Cells
2007
Production of Infectious Chimeric Hepatitis C Virus Genotype 2b Harboring Minimal Regions of JFH-1
2011
CD81 Expression Is Important for the Permissiveness of Huh7 Cell Clones for Heterogeneous Hepatitis C Virus Infection
2007
Nonhepatic Cell Lines HeLa and 293 Support Efficient Replication of the Hepatitis C Virus Genotype 2a Subgenomic Replicon
2004
Interaction of Hepatitis C Virus Nonstructural Protein 5A with Core Protein Is Critical for the Production of Infectious Virus Particles
2008
Novel Cell Culture-Adapted Genotype 2a Hepatitis C Virus Infectious Clone
2012