Citation Impact
Citing Papers
Complement drives Th17 cell differentiation and triggers autoimmune arthritis
2010 StandoutNobel
Interleukin-1 in the pathogenesis and treatment of inflammatory diseases
2011 Standout
Toll‐like receptor 2‐dependent bacterial sensing does not occur via peptidoglycan recognition
2004
Reciprocal T H 17 and Regulatory T Cell Differentiation Mediated by Retinoic Acid
2007 StandoutScience
Group A Streptococcus Activates Type I Interferon Production and MyD88-dependent Signaling without Involvement of TLR2, TLR4, and TLR9
2008 StandoutNobel
The regulation of IL-10 production by immune cells
2010 Standout
Therapeutic potential of complement modulation
2009
Engagement of fatty acids with toll‐like receptor 2 drives interleukin‐1β production via the ASC/caspase 1 pathway in monosodium urate monohydrate crystal–induced gouty arthritis
2010
Inflammatory links between obesity and metabolic disease
2011 Standout
A Crohn's disease–associated NOD2 mutation suppresses transcription of human IL10 by inhibiting activity of the nuclear ribonucleoprotein hnRNP-A1
2009
Attenuation of cardiac dysfunction by HSPA12B in endotoxin-induced sepsis in mice through a PI3K-dependent mechanism
2010
Intestinal homeostasis and its breakdown in inflammatory bowel disease
2011 StandoutNature
Ulcerative Colitis
2011 Standout
Acute Kidney Injury and Chronic Kidney Disease as Interconnected Syndromes
2014 Standout
TLR-dependent and TLR-independent pathways of type I interferon induction in systemic autoimmunity
2007 StandoutNobel
Unravelling the pathogenesis of inflammatory bowel disease
2007 StandoutNature
The NLRP3 inflammasome: molecular activation and regulation to therapeutics
2019 Standout
Shared Principles in NF-κB Signaling
2008 Standout
A cytokine-mediated link between innate immunity, inflammation, and cancer
2007 Standout
Hypoxia and Inflammation
2011 Standout
Recognition of microorganisms and activation of the immune response
2007 StandoutNature
NF-κB, the first quarter-century: remarkable progress and outstanding questions
2012 Standout
Crohn's disease
2012 Standout
Effect of Solar Particle Event Radiation and Hindlimb Suspension on Gastrointestinal Tract Bacterial Translocation and Immune Activation
2012 StandoutNobel
The inhibitory cytokine IL-35 contributes to regulatory T-cell function
2007 StandoutNature
Outer membrane composition of a lipopolysaccharide-deficient Neisseria meningitidis mutant
2001
Pattern Recognition Receptors and Inflammation
2010 Standout
Complement in human diseases: Lessons from complement deficiencies
2009
ATP-sensitive potassium channels mediate survival during infection in mammals and insects
2007 StandoutNobel
Chronic kidney disease worsens sepsis and sepsis-induced acute kidney injury by releasing High Mobility Group Box Protein-1
2011
Inflammatory bowel disease: cause and immunobiology
2007 Standout
The TLR2-MyD88-NOD2-RIPK2 signalling axis regulates a balanced pro-inflammatory and IL-10-mediated anti-inflammatory cytokine response to Gram-positive cell walls
2008
Inflammatory Bowel Disease
2009 Standout
De-escalation therapy among bacteraemic patients with community-acquired pneumonia
2015
Nonresolving Inflammation
2010 Standout
Heat Shock Protein A12B Protects Vascular Endothelial Cells Against Sepsis-Induced Acute Lung Injury in Mice
2017 Standout
Complement: a key system for immune surveillance and homeostasis
2010 Standout
NOD2 and Crohn’s Disease: Loss or Gain of Function?
2005
Bench-to-bedside review: Angiopoietin signalling in critical illness – a future target?
2009
The alternative complement pathway revisited
2008
Functional consequences of NOD2 (CARD15) mutations
2006
NOD2 and Toll-Like Receptors Are Nonredundant Recognition Systems of Mycobacterium tuberculosis
2005
Gout
2016 Standout
Intestinal mucosal barrier function in health and disease
2009 Standout
How regulatory T cells work
2008 Standout
New genes in inflammatory bowel disease: lessons for complex diseases?
2006
Toll-like receptor-4 is required for intestinal response to epithelial injury and limiting bacterial translocation in a murine model of acute colitis
2005
Negative regulation of Toll-like receptor-mediated immune responses
2005
Role of C5a???C5aR Interaction in Sepsis
2003
Alternative Activation of Macrophages: Mechanism and Functions
2010 Standout
Innate Immune Sensing of Microbes by Nod Proteins
2006
Thioredoxin-interacting protein links oxidative stress to inflammasome activation
2009 Standout
Innate immunity in inflammatory bowel disease
2007
The Macrophage Mannose Receptor Induces IL-17 in Response to Candida albicans
2009
The Inflammasomes
2010 Standout
A microbial symbiosis factor prevents intestinal inflammatory disease
2008 StandoutNature
Cytokines in the pathogenesis of rheumatoid arthritis
2007 Standout
Activation of Hypoxia Inducible Factor 1 Is a General Phenomenon in Infections with Human Pathogens
2010
Signalling pathways and molecular interactions of NOD1 and NOD2
2005
Inhibition of toll‐like receptor 4 breaks the inflammatory loop in autoimmune destructive arthritis
2007
Pathogen Recognition and Innate Immunity
2006 Standout
Interactions between Lipid A and Serum Proteins
2009
Does the shape of lipid A determine the interaction of LPS with Toll-like receptors?
2002
Diagnosis and Treatment of Adults with Community-acquired Pneumonia. An Official Clinical Practice Guideline of the American Thoracic Society and Infectious Diseases Society of America
2019 Standout
Coordinated Regulation of Toll-Like Receptor and NOD2 Signaling by K63-Linked Polyubiquitin Chains
2007
Physiological Implications of Hydrogen Sulfide: A Whiff Exploration That Blossomed
2012 Standout
Toll-Like Receptors
2003 Standout
ROLE OF C5A IN INFLAMMATORY RESPONSES
2005
Loss of the autophagy protein Atg16L1 enhances endotoxin-induced IL-1β production
2008 StandoutNature
NOD-Like Receptors: Role in Innate Immunity and Inflammatory Disease
2008
IL-17 and Th17 Cells
2009 Standout
Regulatory T cells suppress systemic and mucosal immune activation to control intestinal inflammation
2006
Immunological and Inflammatory Functions of the Interleukin-1 Family
2009 Standout
IL-32 synergizes with nucleotide oligomerization domain (NOD) 1 and NOD2 ligands for IL-1β and IL-6 production through a caspase 1-dependent mechanism
2005
C3a modulates IL-1β secretion in human monocytes by regulating ATP efflux and subsequent NLRP3 inflammasome activation
2013
Inflammatory Bowel Disease
2010 Standout
NF-κB-dependent induction of microRNA miR-146, an inhibitor targeted to signaling proteins of innate immune responses
2006 StandoutNobel
The microbial metabolite butyrate regulates intestinal macrophage function via histone deacetylase inhibition
2014 Standout
Gout
2021 Standout
COVID-19 and its implications for thrombosis and anticoagulation
2020 Standout
Lipopolysaccharide Endotoxins
2002 Standout
Differential function of the NACHT-LRR (NLR) members Nod1 and Nod2 in arthritis
2008
MyD88 signaling in nonhematopoietic cells protects mice against induced colitis by regulating specific EGF receptor ligands
2010 StandoutNobel
NOD-LRR PROTEINS: Role in Host-Microbial Interactions and Inflammatory Disease
2005
Nod2 Deficiency Augments Th17 Responses and Exacerbates Autoimmune Arthritis
2018 StandoutNobel
Functions of the complement components C3 and C5 during sepsis
2008
Differential requirement for the activation of the inflammasome for processing and release of IL-1β in monocytes and macrophages
2008
Works of Tom Sprong being referenced
Complement plays a central role in C andida albicans ‐induced cytokine production by human PBMC s
2012
Human lipoproteins have divergent neutralizing effects on E. coli LPS, N. meningitidis LPS, and complete Gram-negative bacteria
2004
NOD2 mediates anti‐inflammatory signals induced by TLR2 ligands: implications for Crohn's disease
2004
Effect of antibiotic streamlining on patient outcome in pneumococcal bacteraemia
2014
VASCULAR ENDOTHELIAL GROWTH FACTOR IS INCREASED DURING THE FIRST 48 HOURS OF HUMAN SEPTIC SHOCK AND CORRELATES WITH VASCULAR PERMEABILITY
2005
Contributions ofNeisseria meningitidisLPS and non-LPS to proinflammatory cytokine response
2001
LethalEscherichia coli andSalmonella typhimurium endotoxemia is mediated through different pathways
2001
Inhibition of C5a-induced inflammation with preserved C5b-9-mediated bactericidal activity in a human whole blood model of meningococcal sepsis
2003
Bartonella quintanaLipopolysaccharide Is a Natural Antagonist of Toll-Like Receptor 4
2007
Complement Activation and Complement-Dependent Inflammation byNeisseria meningitidisAre Independent of Lipopolysaccharide
2004