Citation Impact
Citing Papers
Immunomodulatory agents lenalidomide and pomalidomide co‐stimulate T cells by inducing degradation of T cell repressors I karos and A iolos via modulation of the E 3 ubiquitin ligase complex CRL 4 CRBN
2013
Lenalidomide Causes Selective Degradation of IKZF1 and IKZF3 in Multiple Myeloma Cells
2013 Science
Defining the Epithelial Stem Cell Niche in Skin
2003 StandoutScience
The Myeloma Drug Lenalidomide Promotes the Cereblon-Dependent Destruction of Ikaros Proteins
2013 StandoutScienceNobel
Nck adapter proteins: functional versatility in T cells
2009
Reactive Oxygen Species Promote TNFα-Induced Death and Sustained JNK Activation by Inhibiting MAP Kinase Phosphatases
2005 Standout
Molecular mechanism of action of immune-modulatory drugs thalidomide, lenalidomide and pomalidomide in multiple myeloma
2012
An ephrin-A-dependent Signaling Pathway Controls Integrin Function and Is Linked to the Tyrosine Phosphorylation of a 120-kDa Protein
2001
Signal Transduction by the JNK Group of MAP Kinases
2000 Standout
Signal integration by JNK and p38 MAPK pathways in cancer development
2009 Standout
DNA‐Coated AFM Cantilevers for the Investigation of Cell Adhesion and the Patterning of Live Cells
2008 StandoutNobel
Cell Signaling by Receptor Tyrosine Kinases
2010 Standout
Ephrin-A5 modulates cell adhesion and morphology in an integrin-dependent manner
2000
Interleukin-10-Producing Plasmablasts Exert Regulatory Function in Autoimmune Inflammation
2014 StandoutNobel
Excitatory Eph receptors and adhesive ephrin ligands
2001
The Nck-interacting Kinase (NIK) Phosphorylates the Na+-H+ Exchanger NHE1 and Regulates NHE1 Activation by Platelet-derived Growth Factor
2001
Eph/ephrin molecules—a hub for signaling and endocytosis
2010
Clonal Heterogeneity and Tumor Evolution: Past, Present, and the Future
2017 Standout
Transcriptional regulation by calcium, calcineurin, and NFAT
2003 Standout
Arrestin Development: Emerging Roles for β-arrestins in Developmental Signaling Pathways
2009 StandoutNobel
Inflammation, stress, and diabetes
2005 Standout
Nitric Oxide and Peroxynitrite in Health and Disease
2007 Standout
Dissecting muscle and neuronal disorders in a Drosophila model of muscular dystrophy
2007 StandoutNobel
The single-cell transcriptional landscape of mammalian organogenesis
2019 StandoutNature
Heme Oxygenase-1/Carbon Monoxide: From Basic Science to Therapeutic Applications
2006 Standout
A central role for JNK in obesity and insulin resistance
2002 StandoutNature
Cellular processing of platinum anticancer drugs
2005 Standout
Single-cell genetic analysis reveals the composition of initiating clones and phylogenetic patterns of branching and parallel evolution in myeloma
2014
Cell adhesion: integrating cytoskeletal dynamics and cellular tension
2010 Standout
Molecular profiling of angiogenesis in hypericin mediated photodynamic therapy
2008
Phase transitions in the assembly of multivalent signalling proteins
2012 StandoutNature
TAK1 is a ubiquitin-dependent kinase of MKK and IKK
2001 StandoutNature
Mechanisms and functions of eph and ephrin signalling
2002 Standout
From endoplasmic-reticulum stress to the inflammatory response
2008 StandoutNature
Molecular regulation of angiogenesis and lymphangiogenesis
2007 Standout
Multiple signaling interactions of Abl and Arg kinases with the EphB2 receptor
2001
Guidance of regulatory T cell development by Satb1-dependent super-enhancer establishment
2016 StandoutNobel
Free radicals and antioxidants in normal physiological functions and human disease
2006 Standout
Pomalidomide: a novel drug to treat relapsed and refractory multiple myeloma
2013
Different Properties of SEK1 and MKK7 in Dual Phosphorylation of Stress-induced Activated Protein Kinase SAPK/JNK in Embryonic Stem Cells
2003 StandoutNobel
Coming of age: ten years of next-generation sequencing technologies
2016 Standout
The diverse roles of IRF4 in late germinal center B‐cell differentiation
2012
Expanding roles for β-arrestins as scaffolds and adapters in GPCR signaling and trafficking
2001 StandoutNobel
Transposition of native chromatin for fast and sensitive epigenomic profiling of open chromatin, DNA-binding proteins and nucleosome position
2013 Standout
Basic and Therapeutic Aspects of Angiogenesis
2011 Standout
Transcription factor Ikzf1 associates with Foxp3 to repress gene expression in Treg cells and limit autoimmunity and anti-tumor immunity
2024 StandoutNobel
Sensors and regulators of intracellular pH
2009 Standout
Multiple roles of eph receptors and ephrins in neural development
2001
Spontaneous Neural Activity Is Required for the Establishment and Maintenance of the Olfactory Sensory Map
2004 StandoutNobel
Tissue-Resident Macrophage Enhancer Landscapes Are Shaped by the Local Microenvironment
2014 Standout
ATAC-see reveals the accessible genome by transposase-mediated imaging and sequencing
2016 StandoutNobel
Bifocal Is a Downstream Target of the Ste20-like Serine/Threonine Kinase Misshapen in Regulating Photoreceptor Growth Cone Targeting in Drosophila
2002
Structure of the human Cereblon–DDB1–lenalidomide complex reveals basis for responsiveness to thalidomide analogs
2014
Organoid single-cell genomic atlas uncovers human-specific features of brain development
2019 StandoutNatureNobel
Cell Signaling by Receptor Tyrosine Kinases
2000 Standout
Topographic Mapping in Dorsoventral Axis of the Xenopus Retinotectal System Depends on Signaling through Ephrin-B Ligands
2002
Biological Activity of Lenalidomide and Its Underlying Therapeutic Effects in Multiple Myeloma
2012
Peptidic degron in EID1 is recognized by an SCF E3 ligase complex containing the orphan F-box protein FBXO21
2015 StandoutNobel
EphA Receptors Inhibit Anti-CD3-Induced Apoptosis in Thymocytes
2006
The Murine Nck SH2/SH3 Adaptors Are Important for the Development of Mesoderm-Derived Embryonic Structures and for Regulating the Cellular Actin Network
2003
The EphA8 Receptor Regulates Integrin Activity through p110γ Phosphatidylinositol-3 Kinase in a Tyrosine Kinase Activity-Independent Manner
2001
Axonal Ephrin-As and Odorant Receptors
2003 StandoutNobel
Recent developments in myelodysplastic syndromes
2014
Peptidic degron for IMiD-induced degradation of heterologous proteins
2019 StandoutNobel
Mitogen-Activated Protein (MAP) Kinase Pathways: Regulation and Physiological Functions*
2001 Standout
Identification of a Motif in the Carboxyl Terminus of β-Arrestin2 Responsible for Activation of JNK3
2001 StandoutNobel
Downregulation of the Ras–Mitogen-Activated Protein Kinase Pathway by the EphB2 Receptor Tyrosine Kinase Is Required for Ephrin-Induced Neurite Retraction
2001
Nanoparticles in Photodynamic Therapy
2015 Standout
`Eph'ective signaling: forward, reverse and crosstalk
2003
High expression of cereblon (CRBN ) is associated with improved clinical response in patients with multiple myeloma treated with lenalidomide and dexamethasone
2013
Thalidomide promotes degradation of SALL4, a transcription factor implicated in Duane Radial Ray syndrome
2018
Clonal hematopoiesis of indeterminate potential and its distinction from myelodysplastic syndromes
2015 Standout
Cereblon expression is required for the antimyeloma activity of lenalidomide and pomalidomide
2011
Mammalian Mitogen-Activated Protein Kinase Signal Transduction Pathways Activated by Stress and Inflammation
2001 Standout
Lenalidomide efficacy in activated B ‐cell‐like subtype diffuse large B ‐cell lymphoma is dependent upon IRF 4 and cereblon expression
2012
JNK1 controls mast cell degranulation and IL-1β production in inflammatory arthritis
2010 StandoutNobel
SynCAM, a Synaptic Adhesion Molecule That Drives Synapse Assembly
2002 StandoutScienceNobel
Works of Tom Daniel being referenced
Cereblon is a direct protein target for immunomodulatory and antiproliferative activities of lenalidomide and pomalidomide
2012
Lenalidomide downregulates the cell survival factor, interferon regulatory factor‐4, providing a potential mechanistic link for predicting response
2011
Reverse endocytosis of transmembrane ephrin-B ligands via a clathrin-mediated pathway
2004
Measuring cereblon as a biomarker of response or resistance to lenalidomide and pomalidomide requires use of standardized reagents and understanding of gene complexity
2013
Direct Binding with Cereblon Mediates the Antiproliferative and Immunomodulatory Action of Lenalidomide and Pomalidomide
2011
Nck-Interacting Ste20 Kinase Couples Eph Receptors to c-Jun N-Terminal Kinase and Integrin Activation
2000
An activin receptor II A ligand trap promotes erythropoiesis resulting in a rapid induction of red blood cells and haemoglobin
2014