Tom C. Chan

Inference and analysis of cell-cell communication using CellChat

T cell–intrinsic prostaglandin E2-EP2/EP4 signaling is critical in pathogenic TH17 cell–driven inflammation

Heparin-Protein Interactions

DNA methylation and epigenetic inheritance

Single-cell transcriptome analysis of human skin identifies novel fibroblast subpopulation and enrichment of immune subsets in atopic dermatitis

The IL-17 Family of Cytokines in Psoriasis: IL-17A and Beyond

Bacteriophage resistance mechanisms

Psoriasis

T cell pathology in skin inflammation

The JAK/STAT signaling pathway: from bench to clinic

Mechanism of B1 cell differentiation and migration in GALT

Oral Janus kinase/SYK inhibition (ASN002) suppresses inflammation and improves epidermal barrier markers in patients with atopic dermatitis

Hidradenitis suppurativa

PGE2-EP2/EP4 signaling elicits immunosuppression by driving the mregDC-Treg axis in inflammatory tumor microenvironment

The Cellular and Molecular Biology of RNA Tumor Viruses, Especially Avian Leukosis-Sarcoma Viruses, and Their Relatives

Altering Genotype and Phenotype by DNA-Mediated Gene Transfer

Polysaccharide lyases

Molecular Basis of Bacterial Outer Membrane Permeability Revisited

Introduction of a viral thymidine kinase gene and the human β-globin gene into developmentally multipotential mouse teratocarcinoma cells

Adenosine kinase as a new selective marker in somatic cell genetics: Isolation of adenosine kinase-deficient mouse cell lines and human-mouse hybrid cell lines containing adenosine kinase

Skin Resident γδ T Cell Function and Regulation in Wound Repair

Mature dendritic cells enriched in regulatory molecules may control regulatory T cells and the prognosis of head and neck cancer

The oral Janus kinase/spleen tyrosine kinase inhibitorASN002 demonstrates efficacy and improves associated systemic inflammation in patients with moderate‐to‐severe atopic dermatitis: results from a randomized double‐blind placebo‐controlled study

Membrane-Associated Heparan Sulfate Proteoglycan Is a Receptor for Adeno-Associated Virus Type 2 Virions

Variations in sarcoma and leukemia virus activity in somatic cell hybrids

A uridine kinase-deficient mutant of 3T3 and a selective method for cells containing the enzyme

High efficiency transformation by direct microinjection of DNA into cultured mammalian cells

A human-mouse somatic hybrid line selected for human deoxycytidine deaminase

Identification and characterization of a Bacteroides gene, csuF, which encodes an outer membrane protein that is essential for growth on chondroitin sulfate

Purine excretion by mouse peritoneal macrophages lacking adenosine deaminase activity.

Microbial degradation of complex carbohydrates in the gut

Proenkephalin⁺regulatory T cells expanded by ultraviolet B exposure maintain skin homeostasis with a healing function

Transformation of mammalian cells with an amplifiable dominant-acting gene.

Characterization of plant polysaccharide- and mucin-fermenting anaerobic bacteria from human feces

Secretory products of macrophages.

Impaired T cell receptor signaling and development of T cell–mediated autoimmune arthritis

Immunology of Acute and Chronic Wound Healing

Transformation of the gene for hypoxanthine phosphoribosyltransferase

The atopic dermatitis blood signature is characterized by increases in inflammatory and cardiovascular risk proteins

Atopic dermatitis in African American patients is TH2/TH22-skewed with TH1/TH17 attenuation

Psoriasis pathogenesis and the development of novel targeted immune therapies

Isolation and characterization of two chondroitin lyases from Bacteroides thetaiotaomicron

Discovery of the IL-23/IL-17 Signaling Pathway and the Treatment of Psoriasis

Absence of demonstrable linkage of human genes for enzymes of the purine and pyrimidine salvage pathways in human-mouse somatic cell hybrids