Citation Impact
Citing Papers
Detection and quantification of rare mutations with massively parallel sequencing
2011
A "Silent" Polymorphism in the MDR 1 Gene Changes Substrate Specificity
2006 StandoutScience
Controlling Macromolecular Topology with Genetically Encoded SpyTag–SpyCatcher Chemistry
2013 StandoutNobel
X-linked cholestasis in mouse due to mutations of the P4-ATPase ATP11C
2011 StandoutNobel
High burden and pervasive positive selection of somatic mutations in normal human skin
2015 StandoutScience
Plant Cuticular Lipid Export Requires an ABC Transporter
2004 StandoutScience
Detection of ultra-rare mutations by next-generation sequencing
2012
The ABC transporter Bcrp1/ABCG2 is expressed in a wide variety of stem cells and is a molecular determinant of the side-population phenotype
2001 Standout
Piezo1 ion channel pore properties are dictated by C-terminal region
2015 StandoutNobel
Nucleoside-modified VEGFC mRNA induces organ-specific lymphatic growth and reverses experimental lymphedema
2021 StandoutNobel
The homodimeric ATP-binding cassette transporter LmrA mediates multidrug transport by an alternating two-site (two-cylinder engine) mechanism
2000
Multidrug resistance in cancer: role of ATP–dependent transporters
2002 Standout
Cancer statistics, 2020
2020 Standout
Cancer Statistics, 2021
2021 Standout
Therapy-Related Clonal Hematopoiesis in Patients with Non-hematologic Cancers Is Common and Associated with Adverse Clinical Outcomes
2017
The Mechanosensitive Ion Channel Piezo Inhibits Axon Regeneration
2019 StandoutNobel
P-glycoprotein: from genomics to mechanism
2003
A view on drug resistance in cancer
2019 StandoutNature
ABC-ATPases, adaptable energy generators fuelling transmembrane movement of a variety of molecules in organisms from bacteria to humans
1999
Experimental models of inflammatory bowel disease reveal innate, adaptive, and regulatory mechanisms of host dialogue with the microbiota
2005
Hypoxia Regulates CD44 and Its Variant Isoforms through HIF-1α in Triple Negative Breast Cancer
2012 StandoutNobel
Unravelling the pathogenesis of inflammatory bowel disease
2007 StandoutNature
Differential and Simultaneous Adenosine Di- and Triphosphate Binding by MutS
2003 StandoutNobel
Hydrolytically Deficient MutS E694A Is Defective in the MutL-dependent Activation of MutH and in the Mismatch-dependent Assembly of the MutS · MutL · Heteroduplex Complex
2003 StandoutNobel
Cancer drug resistance: an evolving paradigm
2013 Standout
Hallmarks of aging: An expanding universe
2023 Standout
Lamellarin D: a novel pro-apoptotic agent from marine origin insensitive to P-glycoprotein-mediated drug efflux
2004
Identification and Characterization of the Binding Sites of P-Glycoprotein for Multidrug Resistance-Related Drugs and Modulators
2004
Application of second-generation sequencing to cancer genomics
2010
Effect of Solar Particle Event Radiation and Hindlimb Suspension on Gastrointestinal Tract Bacterial Translocation and Immune Activation
2012 StandoutNobel
Induction of Intestinal Th17 Cells by Segmented Filamentous Bacteria
2009 Standout
Design of association studies with pooled or un‐pooled next‐generation sequencing data
2010
Persistent expression of the ATP-binding cassette transporter, Abcg2, identifies cardiac SP cells in the developing and adult heart
2003
Analysis of Circulating Tumor DNA to Monitor Metastatic Breast Cancer
2013 Standout
Recent Developments in mRNA-Based Protein Supplementation Therapy to Target Lung Diseases
2019
Impaired PIEZO1 function in patients with a novel autosomal recessive congenital lymphatic dysplasia
2015 StandoutNobel
Nanocarriers as an emerging platform for cancer therapy
2007 Standout
Inflammatory Bowel Disease
2009 Standout
The role of ABC transporters in drug absorption, distribution, metabolism, excretion and toxicity (ADME–Tox)
2008
Mechanically Activated Ion Channels
2015 StandoutNobel
Cancer stem cells in solid tumours: accumulating evidence and unresolved questions
2008 Standout
Piezos thrive under pressure: mechanically activated ion channels in health and disease
2017 StandoutNobel
Piezo2 is the principal mechanotransduction channel for proprioception
2015 StandoutNobel
Sex and gender: modifiers of health, disease, and medicine
2020 Standout
Clonal Hematopoiesis and Evolution to Hematopoietic Malignancies
2018
Euphorbia factor L1 reverses ABCB1‐mediated multidrug resistance involving interaction with ABCB1 independent of ABCB1 downregualtion
2011
Structure of the mechanically activated ion channel Piezo1
2017 StandoutNatureNobel
Three-dimensional Structures of the Mammalian Multidrug Resistance P-glycoprotein Demonstrate Major Conformational Changes in the Transmembrane Domains upon Nucleotide Binding
2003
Single-Cell Transcriptomic Analysis of Primary and Metastatic Tumor Ecosystems in Head and Neck Cancer
2017 Standout
Functional Characterization of Glycosylation-Deficient Human P-Glycoprotein Using A Vaccinia Virus Expression System
2000
Mammalian drug efflux transporters of the ATP binding cassette (ABC) family: an overview
2003 Standout
Fluoxetine and reversal of multidrug resistance
2005
Microtubules as a target for anticancer drugs
2004 Standout
Predicting drug sensitivity and resistance
2004
SwissADME: a free web tool to evaluate pharmacokinetics, drug-likeness and medicinal chemistry friendliness of small molecules
2017 Standout
The neuronal endopeptidase ECEL1 is associated with a distinct form of recessive distal arthrogryposis
2012
Astrocyte–endothelial interactions at the blood–brain barrier
2005 Standout
High-Affinity Interaction of Tyrosine Kinase Inhibitors with the ABCG2 Multidrug Transporter
2004
Piezo2 senses airway stretch and mediates lung inflation-induced apnoea
2016 StandoutNatureNobel
Molecular damage in aging
2021
Functional Expression and Localization of P-glycoprotein in the Central Nervous System: Relevance to the Pathogenesis and Treatment of Neurological Disorders
2004
The ABC transporter structure and mechanism: perspectives on recent research
2004
Multidrug resistance mediated by the breast cancer resistance protein BCRP (ABCG2)
2003
Small molecules that dramatically alter multidrug resistance phenotype by modulating the substrate specificity of P -glycoprotein
2001
A family of distal arthrogryposis type 5 due to a novel PIEZO2 mutation
2015
Mammalian drug efflux transporters of the ATP binding cassette (ABC) family: an overview
2012 Standout
Tumour stem cells and drug resistance
2005 Standout
Effects of Isoprenoid Analogues ofSDB-Ethylenediamine on Multidrug Resistant Tumor Cells Alone and in Combination with Chemotherapeutic Drugs
2002
Antitumor Antibiotics: Bleomycin, Enediynes, and Mitomycin
2005 Standout
Biomedical and Biotechnological Applications of Elastin-Like Polypeptides
2007
Levels of multidrug resistance (MDR1) P-glycoprotein expression by human breast cancer correlate with in vitro resistance to taxol and doxorubicin.
1998
Chromone: A Valid Scaffold in Medicinal Chemistry
2014 Standout
Piperazinobenzopyranones and Phenalkylaminobenzopyranones: Potent Inhibitors of Breast Cancer Resistance Protein (ABCG2)
2005
Sex ratio among childhood cancers by single year of age
2019
Gain-of-function mutations in the mechanically activated ion channel PIEZO2 cause a subtype of Distal Arthrogryposis
2013 StandoutNobel
ABC Multidrug Transporters: Structure, Function and Role in Chemoresistance
2007
Expression, Up-Regulation, and Transport Activity of the Multidrug-Resistance Protein Abcg2 at the Mouse Blood-Brain Barrier
2004
Mammalian ABC Transporters in Health and Disease
2002
Piezo1, a mechanically activated ion channel, is required for vascular development in mice
2014 StandoutNobel
P-Glycoprotein Protects Leukemia Cells Against Caspase-Dependent, but not Caspase-Independent, Cell Death
1999
P-glycoprotein plays a drug-efflux–independent role in augmenting cell survival in acute myeloblastic leukemia and is associated with modulation of a sphingomyelin-ceramide apoptotic pathway
2000
Studies of Human MDR1-MDR2 Chimeras Demonstrate the Functional Exchangeability of a Major Transmembrane Segment of the Multidrug Transporter and Phosphatidylcholine Flippase
1999
A statistical framework for SNP calling, mutation discovery, association mapping and population genetical parameter estimation from sequencing data
2011 Standout
Quantification and Characterization of P-Glycoprotein−Substrate Interactions
2006
Structure of P-Glycoprotein Reveals a Molecular Basis for Poly-Specific Drug Binding
2009 StandoutScience
The breast cancer resistance protein protects against a major chlorophyll-derived dietary phototoxin and protoporphyria
2002
Euphorbia Diterpenes: Isolation, Structure, Biological Activity, and Synthesis (2008–2012)
2014 Standout
Identification of Chemoresistance-Related Cell-Surface Glycoproteins in Leukemia Cells and Functional Validation of Candidate Glycoproteins
2014
Lamellarins and Related Pyrrole-Derived Alkaloids from Marine Organisms
2007 Standout
A Phase I Trial of a Potent P-Glycoprotein Inhibitor, Zosuquidar Trihydrochloride (LY335979), Administered Intravenously in Combination with Doxorubicin in Patients with Advanced Malignancy
2004
LoFreq: a sequence-quality aware, ultra-sensitive variant caller for uncovering cell-population heterogeneity from high-throughput sequencing datasets
2012
Physiology of Microglia
2011 Standout
Chemical Glycoproteomics
2016 StandoutNobel
Works of Todd E. Druley being referenced
Quantification of rare allelic variants from pooled genomic DNA
2009
Pediatric cancer risk in association with birth defects: A systematic review
2017
Myosin binding protein C1: a novel gene for autosomal dominant distal arthrogryposis type 1
2010
From MDR to MXR: new understanding of multidrug resistance systems, their properties and clinical significance
2001
Clonal haematopoiesis harbouring AML-associated mutations is ubiquitous in healthy adults
2016
Whole-Exome Capture and Sequencing Identifies HEATR2 Mutation as a Cause of Primary Ciliary Dyskinesia
2012
High-throughput discovery of rare insertions and deletions in large cohorts
2010
P-Glycoprotein-Mediated Colchicine Resistance in Different Cell Lines Correlates with the Effects of Colchicine on P-Glycoprotein Conformation
2001
P-glycoprotein function involves conformational transitions detectable by differential immunoreactivity
1997
The evolutionary dynamics and fitness landscape of clonal hematopoiesis
2020 Science
Analysis of MDR1 P-Glycoprotein Conformational Changes in Permeabilized Cells Using Differential Immunoreactivity
2001