Citation Impact
Citing Papers
Histone demethylase KDM6A directly senses oxygen to control chromatin and cell fate
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Structures of Cas9 Endonucleases Reveal RNA-Mediated Conformational Activation
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DNA capture by a CRISPR-Cas9–guided adenine base editor
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Two isoforms of the essential C. elegans Argonaute CSR-1 differentially regulate sperm and oocyte fertility
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Discovery and functional interrogation of SARS-CoV-2 RNA-host protein interactions
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An Integrated Approach for Analysis of the DNA Damage Response in Mammalian Cells
2015 StandoutNobel
Reconstitution of the DNA base excision—repair pathway
1994 StandoutNobel
Enzymes acting at strand interruptions in DNA
1995 StandoutNobel
N6-Methyladenosine in nuclear RNA is a major substrate of the obesity-associated FTO
2011 StandoutNobel
The DBHS proteins SFPQ, NONO and PSPC1: a multipurpose molecular scaffold
2016
Crystal Structure of a Human Alkylbase-DNA Repair Enzyme Complexed to DNA
1998
Crystal Structure of lac Repressor Core Tetramer and Its Implications for DNA Looping
1995 StandoutScienceNobel
Structure of a Voltage-Dependent K+ Channel β Subunit
1999 StandoutNobel
Short-Term Effects of Nose-Only Cigarette Smoke Exposure on Glutathione Redox Homeostasis, Cytochrome P450 1A1/2 and Respiratory Enzyme Activities in Mice Tissues
2013 Standout
DNA base damage induced by ionizing radiation recognized byEscherichia coli UvrABC nuclease but not Nth or Fpg proteins
1996
Analysis of class II (hydrolytic) and class I (β-lyase) apurinic/apyrimidinic endonucleases with a synthetic DNA substrate
1990
Noxious compounds activate TRPA1 ion channels through covalent modification of cysteines
2007 StandoutNatureNobel
Ap endonucleases and dna glycosylases that recognize oxidative dna damage
1988
High-Resolution Mapping Reveals a Conserved, Widespread, Dynamic mRNA Methylation Program in Yeast Meiosis
2013 StandoutNobel
Homologous Recombination but Not Nucleotide Excision Repair Plays a Pivotal Role in Tolerance of DNA-Protein Cross-links in Mammalian Cells
2009
Reactions of oxyl radicals with DNA
1995
Investigating the importance of proteasome-interaction for Rad23 function
2002
Intrinsic disorder in scaffold proteins: Getting more from less
2008
Instability and decay of the primary structure of DNA
1993 StandoutNatureNobel
Release of normal bases from intact DNA by a native DNA repair enzyme
1998
Crystal structures of DNA/RNA repair enzymes AlkB and ABH2 bound to dsDNA
2008 Nature
Activity of Escherichia coli DNA-glycosylases on DNA damaged by methylating and ethylating agents and influence of 3-substituted adenine derivatives
1998
Repair activity of base and nucleotide excision repair enzymes for guanine lesions induced by nitrosative stress
2005
A critical review of permeabilized cell systems for studying mammalian DNA repair
1990
Identification of the Structural and Functional Domains of MutY, an DNA Mismatch Repair Enzyme
1996
The Ogg1 protein of Saccharomyces cerevisiae: a 7,8-dihydro-8- oxoguanine DNA glycosylase/AP lyase whose lysine 241 is a critical residue for catalytic activity
1997
What a difference a hydroxyl makes: mutant IDH, (R)-2-hydroxyglutarate, and cancer
2013 StandoutNobel
Alkylation damage in DNA and RNA—repair mechanisms and medical significance
2004
Molecular Cloning and Functional Analysis of a Human cDNA Encoding an Escherichia Coli AlkB Homolog, a Protein Involved in DNA Alkylation Damage Repair
1996
Oxidative demethylation by Escherichia coli AlkB directly reverts DNA base damage
2002 StandoutNatureNobel
Opposite base-dependent reactions of a human base excision repair enzyme on DNA containing 7,8-dihydro-8-oxoguanine and abasic sites
1997
Enzymic release of 5'-terminal deoxyribose phosphate residues from damaged DNA in human cells
1991 StandoutNobel
Oncogenic Mutations Counteract Intrinsic Disorder in the EGFR Kinase and Promote Receptor Dimerization
2012 StandoutNobel
Human AlkB Homolog 1 Is a Mitochondrial Protein That Demethylates 3-Methylcytosine in DNA and RNA
2008
Preferential recognition of I·T base-pairs in the initiation of excision-repair by hypoxanthine-DNA glycosylase
1991
Purification and Cloning of Micrococcus luteus Ultraviolet Endonuclease, an N-Glycosylase/Abasic Lyase That Proceeds via an Imino Enzyme-DNA Intermediate
1995
DNA Repair: Enzymatic Mechanisms and Relevance to Drug Response
1996
The Exonuclease TREX1 Is in the SET Complex and Acts in Concert with NM23-H1 to Degrade DNA during Granzyme A-Mediated Cell Death
2006
DNA glycosylases
1997
Crystal Structure of a G:T/U Mismatch-Specific DNA Glycosylase
1998
Structures and functions of DNA glycosylases
1990
Cleavage and binding of a DNA fragment containing a single 8-oxoguanine by wild type and mutant FPG proteins
1993
Biological properties of imidazole ring-opened N7-methylguanine in M13mp18 phage DNA
1992
Release of 5′-terminal deoxyribose-phosphate residues from incised abasic sites in DNA by theEscherichia coliRecJ protein
1994 StandoutNobel
Oxidative demethylation of 3‐methylthymine and 3‐methyluracil in single‐stranded DNA and RNA by mouse and human FTO
2008
Beckwith–Wiedemann syndrome
2009
Integrase-mediated spacer acquisition during CRISPR–Cas adaptive immunity
2015 StandoutNatureNobel
Substrate specificities of the Ntg1 and Ntg2 proteins of Saccharomyces cerevisiae for oxidized DNA bases are not identical
1998
Cellular pathways for DNA repair and damage tolerance of formaldehyde-induced DNA-protein crosslinks
2009
Human MMH (OGG1) Type 1a Protein Is a Major Enzyme for Repair of 8-Hydroxyguanine Lesions in Human Cells
1999
Substrate specificity of the Escherichia coli Fpg protein formamidopyrimidine-DNA glycosylase: excision of purine lesions in DNA produced by ionizing radiation or photosensitization
1992
Endogenous lesions, S-phase-independent spontaneous mutations, and evolutionary strategies for base excision repair
1998
Isolation of cDNA clones encoding an enzyme from bovine cells that repairs oxidative DNA damagein vitro: homology with bacterial repair enzymes
1991
Distinct Repair Activities of Human 7,8-Dihydro-8-oxoguanine DNA Glycosylase and Formamidopyrimidine DNA Glycosylase for Formamidopyrimidine and 7,8-Dihydro-8-oxoguanine
2000 StandoutNobel
Stereochemical studies of the .beta.-elimination reactions at aldehydic abasic sites in DNA: endonuclease III from Escherichia coli, sodium hydroxide, and Lys-Trp-Lys
1991
Local Supercoil-Stabilized DNA Structure
1991
Genetics of Food Intake Self-Regulation in Childhood: Literature Review and Research Opportunities
2013 Standout
Analysis of one million base pairs of Neanderthal DNA
2006 StandoutNatureNobel
An alcoholic binge causes massive degradation of hepatic mitochondrial DNA in mice
1999
The enzymology of apurinic/apyrimidinic endonucleases
1990
Trex1 Exonuclease Degrades ssDNA to Prevent Chronic Checkpoint Activation and Autoimmune Disease
2007 StandoutNobel
Accumulation of premutagenic DNA lesions in mice defective in removal of oxidative base damage
1999 StandoutNobel
Cloning and expression in Escherichia coli of the OGG1 gene of Saccharomyces cerevisiae, which codes for a DNA glycosylase that excises 7,8-dihydro-8-oxoguanine and 2,6-diamino-4-hydroxy-5-N-methylformamidopyrimidine.
1996
Highly sensitive apurinic/apyrimidinic site assay can detect spontaneous and chemically induced depurination under physiological conditions.
1998
DNA excision-repair defect of xeroderma pigmentosum prevents removal of a class of oxygen free radical-induced base lesions.
1993 StandoutNobel
Expression of the E.coli 3-methyladenine DNA glycosylase I gene in mammalian cells reduces the toxic and mutagenic effects of methylating agents.
1992
Molecular cloning, expression and catalytic activity of a human AKR7 member of the aldo–keto reductase superfamily: evidence that the major 2-carboxybenzaldehyde reductase from human liver is a homologue of rat aflatoxin B1-aldehyde reductase
1998
Generation of Single-Nucleotide Repair Patches Following Excision of Uracil Residues from DNA
1992 StandoutNobel
Patterns of nucleotide misincorporations during enzymatic amplification and direct large-scale sequencing of ancient DNA
2006 StandoutNobel
Structure of the STRA6 receptor for retinol uptake
2016 StandoutScienceNobel
In vitro repair of oxidative DNA damage by human nucleotide excision repair system: Possible explanation for neurodegeneration in Xeroderma pigmentosum patients
1997 StandoutNobel
Influence of supercoiling and sequence context on operator DNA binding with lac repressor.
1987
Mutation of the mouse klotho gene leads to a syndrome resembling ageing.
1997 Standout
Mechanism of Action of Base Release by Escherichia coli Fpg Protein: Role of Lysine 155 in Catalysis
1997
Repair of intrinsic DNA lesions
1990 StandoutNobel
Quality Control by DNA Repair
1999 StandoutScienceNobel
Patterns of damage in genomic DNA sequences from a Neandertal
2007 StandoutNobel
Reconstructing the DNA Methylation Maps of the Neandertal and the Denisovan
2014 StandoutScienceNobel
Potency of Michael reaction acceptors as inducers of enzymes that protect against carcinogenesis depends on their reactivity with sulfhydryl groups
2001
3, N 4 -ethenocytosine, a highly mutagenic adduct, is a primary substrate for Escherichia coli double-stranded uracil-DNA glycosylase and human mismatch-specific thymine-DNA glycosylase
1998
The Catalytic Mechanism of Fpg Protein
1995
Human DNA ligase I cDNA: cloning and functional expression in Saccharomyces cerevisiae.
1990 StandoutNobel
DNA Mismatch Repair: Functions and Mechanisms
2005 StandoutNobel
AID-induced decrease in topoisomerase 1 induces DNA structural alteration and DNA cleavage for class switch recombination
2009 StandoutNobel
Substrate spectrum of human excinuclease: repair of abasic sites, methylated bases, mismatches, and bulky adducts.
1994 StandoutNobel
Chemistry of Glycosylases and Endonucleases Involved in Base-Excision Repair
1998
8-Hydroxyguanine, an abundant form of oxidative DNA damage, causes G-T and A-C substitutions.
1992 Standout
Temperature dependence of the dynamic light scattering of linear ϕ29 DNA: Implications for spontaneous opening of the double‐helix
1983
Excision of Deoxyribose Phosphate Residues by DNA Polymerase β During DNA Repair
1995 Science
Noroviruses subvert the core stress granule component G3BP1 to promote viral VPg-dependent translation
2019
Non-B right-handed DNA conformations of homopurine.homopyrimidine sequences in the murine immunoglobulin C alpha switch region.
1988
Purification and characterization of a novel deoxyinosine-specific enzyme, deoxyinosine 3' endonuclease, from Escherichia coli.
1994
The GO system protects organisms from the mutagenic effect of the spontaneous lesion 8-hydroxyguanine (7,8-dihydro-8-oxoguanine)
1992
DNA glycosylases in the base excision repair of DNA
1997
Cloning and characterization of a functional human homolog of Escherichia coli endonuclease III
1997 StandoutNobel
Evidence for two DNA repair enzymes for 8-hydroxyguanine (7,8-dihydro-8-oxoguanine) in human cells.
1993
Reversal of DNA alkylation damage by two human dioxygenases
2002 StandoutNobel
Molecular cloning and functional expression of a human cDNA encoding the antimutator enzyme 8-hydroxyguanine-DNA glycosylase
1997 StandoutNobel
Enzymatic Processing of Radiation-Induced Free Radical Damage in DNA
1998
Suppressing Brownian motion of individual biomolecules in solution
2006 StandoutNobel
Circadian control of XPA and excision repair of cisplatin-DNA damage by cryptochrome and HERC2 ubiquitin ligase
2010 StandoutNobel
Mechanistic Studies on Synthetic Fe−S-Based Clusters and Their Relevance to the Action of Nitrogenases
2005 StandoutNobel
Structural diversity of calmodulin binding to its target sites
2013
Generation of single-nucleotide repair patches following excision of uracil residues from DNA.
1992 StandoutNobel
Removal of oxygen free-radical-induced 5′,8-purine cyclodeoxynucleosides from DNA by the nucleotide excision-repair pathway in human cells
2000 StandoutNobel
Scanning the human proteome for calmodulin-binding proteins
2005 StandoutNobel
8-oxoguanine (8-hydroxyguanine) DNA glycosylase and its substrate specificity.
1991
Repair of DNA–polypeptide crosslinks by human excision nuclease
2006 StandoutNobel
Escherichia coli Fpg protein and UvrABC endonuclease repair DNA damage induced by methylene blue plus visible light in vivo and in vitro
1991
Molecular cloning of human uracil-DNA glycosylase, a highly conserved DNA repair enzyme.
1989
Cloning and characterization of mammalian 8-hydroxyguanine-specific DNA glycosylase/apurinic, apyrimidinic lyase, a functional mutM homologue.
1997
Human nucleotide excision nuclease removes thymine dimers from DNA by incising the 22nd phosphodiester bond 5' and the 6th phosphodiester bond 3' to the photodimer.
1992 StandoutNobel
Works of Timothy O’Connor being referenced
Cupric ion/ascorbate/hydrogen peroxide-induced DNA damage: DNA-bound copper ion primarily induces base modifications
1996
Excision of DNA adducts of nitrogen mustards by bacterial and mammalian 3-methyladenine-DNA glycosylases
1996
Defining the RGG/RG Motif
2013
Isolation and structure of a cDNA expressing a mammalian 3-methyladenine-DNA glycosylase.
1990
Ring-opened 7-methylguanine residues in DNA are a block to in vitro DNA synthesis
1988
Effect of alkyl-N-purine DNA glycosylase overexpression on cellular resistance to bifunctional alkylating agents
1995
Nucleotide Excision Repair Eliminates Unique DNA-Protein Cross-links from Mammalian Cells
2007
Calmodulin signaling: Analysis and prediction of a disorder‐dependent molecular recognition
2006
Repair of Methylation Damage in DNA and RNA by Mammalian AlkB Homologues
2005
Methylation of cytosine in the 5-position alters the structural and energetic properties of the supercoil-induced Z-helix and B-Z junctions
1988
Heterogeneous repair of N -methylpurines at the nucleotide level in normal human cells 1 1Edited by M. Yahiv
1998
Physiological properties and repair of apurinic/apyrimidinic sites and imidazole ring-opened guanines in DNA
1990
Human cDNA expressing a functional DNA glycosylase excising 3-methyladenine and 7-methylguanine
1991
3-Methyladenine-DNA Glycosylase (MPG Protein) Interacts with Human RAD23 Proteins
2000
Serum α-fetoprotein screening for hepatoblastoma in children with Beckwith-Wiedemann syndrome or isolated hemihyperplasia
2003
Mechanism of DNA strand nicking at apurinic/apyrimidinic sites by Escherichia coli [formamidopyrimidine]DNA glycosylase
1989
Homogeneous Escherichia coli FPG protein. A DNA glycosylase which excises imidazole ring-opened purines and nicks DNA at apurinic/apyrimidinic sites.
1990
Characterization of the 3‘ → 5‘ Exonuclease Activity Found in Human Nucleoside Diphosphate Kinase 1 (NDK1) and Several of Its Homologues
2005
Formamidopyrimidine-DNA glycosylase of Escherichia coli: cloning and sequencing of the fpg structural gene and overproduction of the protein.
1987
Left-handed DNA Helices, Supercoiling, and the B-Z Junction
1983
Stability, Miscoding Potential, and Repair of 2‘-Deoxyxanthosine in DNA: Implications for Nitric Oxide-Induced Mutagenesis
2003
Physical association of the 2,6-diamino-4-hydroxy-5N-formamidopyrimidine-DNA glycosylase of Escherichia coli and an activity nicking DNA at apurinic/apyrimidinic sites.
1989
The pH-dependent structure of calf thymus DNA studied by Raman spectroscopy
1982
Thermodynamic parameters are sequence-dependent for the supercoil-induced B to Z transition in recombinant plasmids.
1986
Excision of 5'-terminal deoxyribose phosphate from damaged DNA is catalyzed by the Fpg protein of Escherichia coli.
1992
Regulation of carbonyl-reducing enzymes in rat liver by chemoprotectors.
1996
Fpg protein of Escherichia coli is a zinc finger protein whose cysteine residues have a structural and/or functional role.
1993