Citation Impact
Citing Papers
Anti-Markovnikov alkene oxidation by metal-oxo–mediated enzyme catalysis
2017 StandoutScienceNobel
Observation of Covalent Intermediates in an Enzyme Mechanism at Atomic Resolution
2001 Science
Directed evolution of a genetic circuit
2002 StandoutNobel
The mucin-selective protease StcE enables molecular and functional analysis of human cancer-associated mucins
2019 StandoutNobel
Origins of catalysis by computationally designed retroaldolase enzymes
2010 StandoutNobel
Tight and specific lanthanide binding in a de novo TIM barrel with a large internal cavity designed by symmetric domain fusion
2020 StandoutNobel
Computational Design of an Enzyme Catalyst for a Stereoselective Bimolecular Diels-Alder Reaction
2010 StandoutScienceNobel
Hierarchical design of pseudosymmetric protein nanocages
2024 StandoutNatureNobel
Computational design of soluble and functional membrane protein analogues
2024 StandoutNatureNobel
The (S)‐Proline/Polyelectrolyte System: An Efficient, Heterogeneous, Reusable Catalyst for Direct Asymmetric Aldol Reactions
2006
The Aldol Addition Reaction: An Old Transformation at Constant Rebirth
2002
Discovery of new peptide-Based catalysts for the direct asymmetric aldol reaction
2003
Asymmetric Direct Aldol Reaction Assisted by Water and a Proline‐Derived Tetrazole Catalyst
2004 Standout
Physical Principles of Membrane Shape Regulation by the Glycocalyx
2019 StandoutNobel
Enantioselective Organocatalytic Direct Aldol Reactions of α‐Oxyaldehydes: Step One in a Two‐Step Synthesis of Carbohydrates
2004
Development of protein, peptide, and small molecule catalysts using catalysis‐based selection strategies
2005
Amino Acids—Valuable Organocatalysts in Carbohydrate Synthesis
2005
Combinatorial and computational challenges for biocatalyst design
2001 StandoutNatureNobel
The Origin of Stereoselectivity in Primary Amino Acid Catalyzed Intermolecular Aldol Reactions
2005
Directed enzyme evolution
2001 StandoutNobel
Asymmetric direct aldol reaction catalyzed by an l-prolinamide derivative: considerable improvement of the catalytic efficiency in the ionic liquid
2005
Direct Catalytic Asymmetric Enolexo Aldolizations
2003 StandoutNobel
The road to fully programmable protein catalysis
2022 StandoutNatureNobel
Emil Knoevenagel and the Roots of Aminocatalysis
2010 StandoutNobel
Engineering aldolases as biocatalysts
2014
The Mukaiyama Aldol Reaction: 40 Years of Continuous Development
2013
Directed Evolution as a Method To Create Enantioselective Cyclohexanone Monooxygenases for Catalysis in Baeyer–Villiger Reactions
2004
Amino Acid Catalyzed Neogenesis of Carbohydrates: A Plausible Ancient Transformation
2005
Asymmetric Catalysis by Chiral Hydrogen‐Bond Donors
2006 Standout
Highly Diastereo‐ and Enantioselective Direct Aldol Reactions in Water
2005
Laboratory Evolution of Stereoselective Enzymes: A Prolific Source of Catalysts for Asymmetric Reactions
2010
Acyclic amino acid-catalyzed direct asymmetric aldol reactions: alanine, the simplest stereoselective organocatalyst
2005
The direct catalytic asymmetric aldol reaction
2010
The Direct Catalytic Asymmetric Cross‐Aldol Reaction of Aldehydes
2003
Direct Organocatalytic De Novo Synthesis of Carbohydrates
2005
Direct Amino Acid Catalyzed Asymmetric Synthesis of Polyketide Sugars
2004
Current progress in the asymmetric aldol addition reaction
2004
Organocatalytic Enantioselective Decarboxylative Aldol Reaction of Malonic Acid Half Thioesters with Aldehydes
2013 StandoutNobel
Cloning, isolation and characterization of the Thermotoga maritima KDPG aldolase
2002
Direct Asymmetric Intermolecular Aldol Reactions Catalyzed by Amino Acids and Small Peptides
2006
The coming of age of de novo protein design
2016 StandoutNatureNobel
Evidence for the Formation of an Enamine Species during Aldol and Michael‐type Addition Reactions Promiscuously Catalyzed by 4‐Oxalocrotonate Tautomerase
2015
Approaching sub-ppm-level asymmetric organocatalysis of a highly challenging and scalable carbon–carbon bond forming reaction
2018 StandoutNobel
Directed evolution and the creation of enantioselective biocatalysts
2001
Enantioselective Intramolecular Aldol Addition/Dehydration Reaction of a Macrocyclic Diketone: Synthesis of the Musk Odorants (R)‐Muscone and (R,Z)‐5‐Muscenone
2007
Small peptides as modular catalysts for the direct asymmetric aldol reaction: ancient peptides with aldolase enzyme activity
2005
The Dihydroxyacetone Unit—A Versatile C3Building Block in Organic Synthesis
2005
The Cross‐Dehydrogenative Coupling of CH Bonds: A Versatile Strategy for CC Bond Formations
2013 Standout
Proline-catalysed Mannich reactions of acetaldehyde
2008 StandoutNatureNobel
The Organic Approach to Asymmetric Catalysis
2006 StandoutScienceNobel
ESI-MS study on the aldol reaction catalyzed by l-proline
2006
Kinetic Resolution of Quaternary and Tertiary β‐Hydroxy Esters
2009
Mechanism of the Class I KDPG aldolase
2006
Asymmetric Multicomponent Reactions (AMCRs): The New Frontier
2005 Standout
A Diarylprolinol in an Asymmetric, Catalytic, and Direct Crossed‐Aldol Reaction of Acetaldehyde
2008
The small peptide-catalyzed direct asymmetric aldol reaction in water
2005
Highly Efficient and Reusable Dendritic Catalysts Derived fromN-Prolylsulfonamide for the Asymmetric Direct Aldol Reaction in Water
2006
Kinetic Resolution of Quaternary and Tertiary β‐Hydroxy Esters
2009
Amino acids and peptides as asymmetric organocatalysts
2002
New mechanistic studies on the proline-catalyzed aldol reaction
2004 StandoutNobel
4,4′‐Disubstituted L ‐Prolines as Highly Enantioselective Catalysts for Direct Aldol Reactions
2006
Room-Temperature Ionic Liquids: Solvents for Synthesis and Catalysis. 2
2011 Standout
Artificial Metalloenzymes for Enantioselective Catalysis Based on Biotin−Avidin
2003
Amino Acid‐Catalyzed Asymmetric Carbohydrate Formation: Organocatalytic One‐Step De Novo Synthesis of Keto and Amino Sugars
2006
Polystyrene-Supported Hydroxyproline: An Insoluble, Recyclable Organocatalyst for the Asymmetric Aldol Reaction in Water
2006
Proline-catalysed asymmetric aldol reaction in the room temperature ionic liquid [bmim]PF6
2002
Sterically and Electronically Tunable and Bifunctional Organocatalysts: Design and Application in Asymmetric Aldol Reaction of Cyclic Ketones with Aldehydes
2006
Chiral Primary Amine Catalyzed Asymmetric Direct Cross‐Aldol Reaction of Acetaldehyde
2011
The Origin of Stereoselectivity in Proline-Catalyzed Intramolecular Aldol Reactions
2001
In the light of directed evolution: Pathways of adaptive protein evolution
2009 StandoutNobel
Artificial Metalloenzymes: (Strept)avidin as Host for Enantioselective Hydrogenation by Achiral Biotinylated Rhodium−Diphosphine Complexes
2004
Efficiency in Isotetronic Acid Synthesis via a Diamine−Acid Couple Catalyzed Ethyl Pyruvate Homoaldol Reaction
2005
Chemical Glycobiology
2001 StandoutScienceNobel
Stereochemistry of Aldols: Configuration and Conformation of Aldols Derived from Cycloalkanones and Aldehydes
2001 StandoutNobel
The Direct Catalytic Asymmetric Aldol Reaction
2002
The Application of L-Proline as an Enzyme Mimic and Further New Asymmetric Syntheses Using Small Organic Molecules as Chiral Catalysts
2001
Crystal structures of proline-derived enamines
2010 StandoutNobel
Sodium Phenoxide−Phosphine Oxides as Extremely Active Lewis Base Catalysts for the Mukaiyama Aldol Reaction with Ketones
2007
Direct, pyrrolidine sulfonamide promoted enantioselective aldol reactions of α,α-dialkyl aldehydes: synthesis of quaternary carbon-containing β-hydroxy carbonyl compounds
2005
Amino acid catalyzed direct enantioselective formation of carbohydrates: one-step de novo synthesis of ketoses
2005
Recent applications of organocatalysts in asymmetric aldol reactions
2012
Design of Protein Catalysts
2013
Combining proline and ‘click chemistry’: a class of versatile organocatalysts for the highly diastereo- and enantioselective Michael addition in water
2006
β- N -acetylglucosamine (O-GlcNAc) is part of the histone code
2010
Catalytic, Asymmetric Transannular Aldolizations: Total Synthesis of (+)-Hirsutene
2008 StandoutNobel
Catalytic Asymmetric Hydroalkoxylation of C–C Multiple Bonds
2021 StandoutNobel
A Diarylprolinol in an Asymmetric, Catalytic, and Direct Crossed‐Aldol Reaction of Acetaldehyde
2008
Transition States of Amine-Catalyzed Aldol Reactions Involving Enamine Intermediates: Theoretical Studies of Mechanism, Reactivity, and Stereoselectivity
2001
High acceleration of the direct aldol reaction cocatalyzed by BINAM-prolinamides and benzoic acid in aqueous media
2006
C−C Bond-Forming Lyases in Organic Synthesis
2011
Mimicking Dihydroxy Acetone Phosphate-Utilizing Aldolases through Organocatalysis: A Facile Route to Carbohydrates and Aminosugars
2005
The Crucial Role of Methodology Development in Directed Evolution of Selective Enzymes
2019
Asymmetric aldol reactions catalyzed by new spiro diamine derivatives
2006
Direct Catalytic Asymmetric Enolexo Aldolizations
2003 StandoutNobel
Kinetic Resolution of Homoaldols via Catalytic Asymmetric Transacetalization
2010 StandoutNobel
A direct intramolecular asymmetric catalytic aldol cyclodehydration of meso-3,4-disubstituted-1,6-dialdehydes
2004
Chemically tunable mucin chimeras assembled on living cells
2015 StandoutNobel
Confined acids catalyze asymmetric single aldolizations of acetaldehyde enolates
2018 StandoutScienceNobel
Organic Reactions in Aqueous Media with a Focus on Carbon−Carbon Bond Formations: A Decade Update
2005 Standout
Biocatalysis in Organic Chemistry and Biotechnology: Past, Present, and Future
2013
Organocatalyzed direct aldol condensation using l-proline and BINAM-prolinamides: regio-, diastereo-, and enantioselective controlled synthesis of 1,2-diols
2006
Amino acid-catalyzed dynamic kinetic asymmetric transformations (DYKAT): one-step de novo synthesis of polyketide sugars from racemic β-hydroxy aldehydes
2005
Enzyme Redesign
2001
BINAM-prolinamides as recoverable catalysts in the direct aldol condensation
2006
Diversity-based strategy for discovery of environmentally benign organocatalyst: diamine–protonic acid catalysts for asymmetric direct aldol reaction
2002
Chemomimetic Biocatalysis: Exploiting the Synthetic Potential of Cofactor-Dependent Enzymes To Create New Catalysts
2015 StandoutNobel
IDPi Catalysis
2019 StandoutNobel
FUTURE TRENDS IN BIOSENSOR RESEARCH
2001
Development of Novel Lewis Acid Catalysts for Selective Organic Reactions in Aqueous Media
2002 Standout
De Novo Computational Design of Retro-Aldol Enzymes
2008 StandoutScienceNobel
Design of a hyperstable 60-subunit protein icosahedron
2016 StandoutNatureNobel
Enamine-Based Organocatalysis with Proline and Diamines: The Development of Direct Catalytic Asymmetric Aldol, Mannich, Michael, and Diels−Alder Reactions
2004
The Putative Diels−Alderase Macrophomate Synthase is an Efficient Aldolase
2008
Direct catalytic asymmetric cross-aldol reactions in ionic liquid media
2004
Regio- and Enantioselective Alkane Hydroxylation with Engineered Cytochromes P450 BM-3
2003 StandoutNobel
Proline‐Derived N‐Sulfonylcarboxamides: Readily Available, Highly Enantioselective and Versatile Catalysts for Direct Aldol Reactions
2004
The Direct Catalytic Asymmetric Mannich Reaction
2004
The state of the art in asymmetric induction: the aldol reaction as a case study
2009
Gold-Catalyzed Organic Reactions
2007 Standout
Catalytic Versatility, Stability, and Evolution of the (βα)8-Barrel Enzyme Fold
2005
Direct asymmetric organocatalytic de novo synthesis of carbohydrates
2005
Cu-Catalyzed Azide−Alkyne Cycloaddition
2008 StandoutNobel
Enantioselective organocatalytic aldol reaction using small organic molecules
2012
Die Anwendung vonL-Prolin als Enzymmimetikum und weitere neue asymmetrische Synthesen mit kleinen organischen Molekülen als chiralen Katalysatoren
2001
Dynamic Control of Chiral Space in a Catalytic Asymmetric Reaction Using a Molecular Motor
2011 StandoutScienceNobel
Synthesis of Complex Carbohydrates and Glycoconjugates: Enzyme-Based and Programmable One-Pot Strategies
2000
Asymmetric Enamine Catalysis
2007 StandoutNobel
Quantum Mechanical Predictions of the Stereoselectivities of Proline-Catalyzed Asymmetric Intermolecular Aldol Reactions
2003 StandoutNobel
Enantioselective organocatalytic aldehyde–aldehyde cross-aldol couplings. The broad utility of α-thioacetal aldehydes
2004
Highly Diastereo‐ and Enantioselective Direct Aldol Reactions in Water
2005
Direct Asymmetric Aldol Reactions of Acetone Using Bimetallic Zinc Catalysts
2001
Impact of scaffold rigidity on the design and evolution of an artificial Diels-Alderase
2014 StandoutNobel
Chiral Ionic Liquid Containing l -Proline Unit as a Highly Efficient and Recyclable Asymmetric Organocatalyst for Aldol Reaction
2007
Principles of Mucin Architecture: Structural Studies on Synthetic Glycopeptides Bearing Clustered Mono-, Di-, Tri-, and Hexasaccharide Glycodomains
2002
Chemical Glycoproteomics
2016 StandoutNobel
Direct Catalytic Asymmetric Aldol Reaction of Hydroxyketones: Asymmetric Zn Catalysis with a Et2Zn/Linked-BINOL Complex
2003
Design of Acid−Base Catalysis for the Asymmetric Direct Aldol Reaction
2004
Fluorescence Resonance Energy Transfer Between Quantum Dot Donors and Dye-Labeled Protein Acceptors
2003 StandoutNobel
Works of Timothy Machajewski being referenced
Directed evolution of D-2-keto-3-deoxy-6-phosphogluconate aldolase to new variants for the efficient synthesis of D- and L-sugars
2000
The Catalytic Asymmetric Aldol Reaction
2000
Die katalysierte asymmetrische Aldolreaktion
2000
Chemoenzymatic Synthesis of Key Epothilone Fragments
1999
Glycosylation of Threonine of the Repeating Unit of RNA Polymerase II with β-Linked N-Acetylglucosame Leads to a Turnlike Structure
1998
One-Pot Synthesis of l -Fructose Using Coupled Multienzyme Systems Based on Rhamnulose-1-phosphate Aldolase
2003