Citation Impact

Citing Papers

Specialized Persister Cells and the Mechanism of Multidrug Tolerance in Escherichia coli
2004
Bacterial Persistence as a Phenotypic Switch
2004 StandoutScience
Strategy for Dual-Analyte Luciferin Imaging: In Vivo Bioluminescence Detection of Hydrogen Peroxide and Caspase Activity in a Murine Model of Acute Inflammation
2013 StandoutNobel
Regulation of phenotypic variability by a threshold-based mechanism underlies bacterial persistence
2010
Cytoplasmic steps of peptidoglycan biosynthesis
2008
Proteases in Escherichia coli and Staphylococcus aureus confer reduced susceptibility to lactoferricin B
2002
Global, regional, and national age–sex specific all-cause and cause-specific mortality for 240 causes of death, 1990–2013: a systematic analysis for the Global Burden of Disease Study 2013
2014 Standout
Discovery of chlamydial peptidoglycan reveals bacteria with murein sacculi but without FtsZ
2013
Mechanism of antimicrobial action of indolicidin
1998
The relationship between peptide structure and antibacterial activity
2003
The Chlamydial Anomaly Clarified?
2014
Cationic antimicrobial peptides activate a two‐component regulatory system, PmrA‐PmrB, that regulates resistance to polymyxin B and cationic antimicrobial peptides in Pseudomonas aeruginosa
2003
Persister cells and tolerance to antimicrobials
2003
Peptidoglycan structure and architecture
2008 Standout
Parvovirus-associated arthritis
2000
Burden of disease caused by Streptococcus pneumoniae in children younger than 5 years: global estimates
2009 Standout
Persister cells, dormancy and infectious disease
2006
Formation and Characterization of a Single Trp-Trp Cross-link in Indolicidin That Confers Protease Stability without Altering Antimicrobial Activity
2000
The Human Cathelicidin LL-37 Has Antiviral Activity against Respiratory Syncytial Virus
2013 StandoutNobel
Phenotypic Landscape of a Bacterial Cell
2010
Structural and DNA-binding studies on the bovine antimicrobial peptide, indolicidin: evidence for multiple conformations involved in binding to membranes and DNA
2005
Global burden of childhood pneumonia and diarrhoea
2013 Standout
Function of the drosophila pattern-recognition receptor PGRP-SD in the detection of Gram-positive bacteria
2004 StandoutNobel
Antimicrobial peptides in mammalian and insect host defence
1999
Extreme antimicrobial peptide and polymyxin B resistance in the genus Burkholderia
2011
Mechanism of the binding, insertion and destabilization of phospholipid bilayer membranes by α-helical antimicrobial and cell non-selective membrane-lytic peptides
1999 Standout
PR-39, a Syndecan-inducing Antimicrobial Peptide, Binds and Affects p130Cas
1998
Antimicrobial Peptides as Mediators of Epithelial Host Defense
1999
Microbial Persistence and the Road to Drug Resistance
2013
Mechanisms of polymyxin resistance: acquired and intrinsic resistance in bacteria
2014 Standout
Binding a heparin derived disaccharide to defensin inspired peptides: insights to antimicrobial inhibition from gas-phase measurements
2010 StandoutNobel
Mode of action of linear amphipathic α-helical antimicrobial peptides
1998
New-found fundamentals of bacterial persistence
2012
Extreme Antimicrobial Peptide and Polymyxin B Resistance in the Genus Burkholderia
2011
Antimicrobial peptides of vertebrates
1998
Antimicrobial agents
1997
Properties and structure–activity studies of cyclic β-hairpin peptidomimetics based on the cationic antimicrobial peptide protegrin I
2005
A new metabolic cell-wall labelling method reveals peptidoglycan in Chlamydia trachomatis
2013 Nature
The Science of Antibiotic Discovery
2020 Standout
Structural Requirements for Potent Versus Selective Cytotoxicity for Antimicrobial Dermaseptin S4 Derivatives
2002
Building the invisible wall: updating the chlamydial peptidoglycan anomaly
2006
Prokaryotic toxin–antitoxin stress response loci
2005
A multinational, randomized phase iii trial of iseganan hcl oral solution for reducing the severity of oral mucositis in patients receiving radiotherapy for head-and-neck malignancy
2004
Transgenic plants expressing cationic peptide chimeras exhibit broad-spectrum resistance to phytopathogens
2000
Malaria
2013 Standout
Hydrophobicity, hydrophobic moment and angle subtended by charged residues modulate antibacterial and haemolytic activity of amphipathic helical peptides
1997
High Persister Mutants in Mycobacterium tuberculosis
2016
Peptide antibiotics
1997
Influence of preformed α‐helix and α‐helix induction on the activity of cationic antimicrobial peptides
1998
Ciprofloxacin Causes Persister Formation by Inducing the TisB toxin in Escherichia coli
2010
Interaction of antimicrobial peptides with biological and model membranes: structural and charge requirements for activity
1999
Drosophila innate immunity: an evolutionary perspective
2002 StandoutNobel
A Chromatin-Mediated Reversible Drug-Tolerant State in Cancer Cell Subpopulations
2010 Standout
Illumination of growth, division and secretion by metabolic labeling of the bacterial cell surface
2015 StandoutNobel
Cationic peptides: a new source of antibiotics
1998
Lipid-induced conformation and lipid-binding properties of cytolytic and antimicrobial peptides: determination and biological specificity
1999
Can innate immunity be enhanced to treat microbial infections?
2004
Structure–activity relationships for the β-hairpin cationic antimicrobial peptide polyphemusin I
2004
Analysis and Separation of Residues Important for the Chemoattractant and Antimicrobial Activities of β-Defensin 3
2008 StandoutNobel
Mechanisms of Antimicrobial Peptide Action and Resistance
2003 Standout
Mechanisms of Action for Antimicrobial Peptides With Antibacterial and Antibiofilm Functions
2019
Programmed population control by cell–cell communication and regulated killing
2004 StandoutNatureNobel
Structure and Biology of Cathelicidins
2002
Antibacterial photodynamic therapy in dermatology
2004
Signal Transduction by a Death Signal Peptide
2000 StandoutNobel
Efficacy assessment of a cell-mediated immunity HIV-1 vaccine (the Step Study): a double-blind, randomised, placebo-controlled, test-of-concept trial
2008 Standout
Hospital-Acquired Infections Due to Gram-Negative Bacteria
2010 Standout
Requirements for high impact diagnostics in the developing world
2006 StandoutNature
The evolution and genetics of innate immunity
2001 StandoutNobel
How do bacteria resist human antimicrobial peptides?
2002
Randomised trial of Haemophilus influenzae type-b tetanus protein conjugate for prevention of pneumonia and meningitis in Gambian infants
1997
Induction of cathelicidin in normal and CF bronchial epithelial cells by 1,25-dihydroxyvitamin D3
2007
Interaction of Cationic Antimicrobial Peptides with Model Membranes
2001
Structure determination of human and murine β‐defensins reveals structural conservation in the absence of significant sequence similarity
2001
Cecropins induce the hyperosmotic stress response in Escherichia coli
1998
In vitro and in vivo antimicrobial activity of two α-helical cathelicidin peptides and of their synthetic analogs
2003
A Putative Src Homology 3 Domain Binding Motif but Not the C-terminal Dystrophin WW Domain Binding Motif Is Required for Dystroglycan Function in Cellular Polarity in Drosophila
2007 StandoutNobel
Antimicrobial peptides of multicellular organisms
2002 StandoutNature
From “carpet” mechanism to de-novo designed diastereomeric cell-selective antimicrobial peptides
2001
Cationic host defense (antimicrobial) peptides
2005
A Common Mechanism of Cellular Death Induced by Bactericidal Antibiotics
2007 Standout
Parvovirus B19
2004 Standout
Antibacterial drug discovery in the resistance era
2016 StandoutNature
How many child deaths can we prevent this year?
2003 Standout
Antimicrobial and host-defense peptides as new anti-infective therapeutic strategies
2006 Standout
Multidrug Tolerance of Biofilms and Persister Cells
2008
Diversity of antimicrobial peptides and their mechanisms of action
1999
Polar Angle as a Determinant of Amphipathic α-Helix-Lipid Interactions: A Model Peptide Study
2000
Bacteremia among Children Admitted to a Rural Hospital in Kenya
2005
Structure determination of human and murine beta-defensins reveals structural conservation in the absence of significant sequence similarity
2001
Bacterial Persistence and Toxin-Antitoxin Loci
2012
Pseudomonas aeruginosa Reveals High Intrinsic Resistance to Penem Antibiotics: Penem Resistance Mechanisms and Their Interplay
2001
Specific Lipopolysaccharide Found in Cystic Fibrosis Airway Pseudomonas aeruginosa
1999 Science
Peptide Antimicrobial Agents
2006 Standout
Invited review: Diversity of endotoxin and its impact on pathogenesis
2006
GlpD and PlsB Participate in Persister Cell Formation in Escherichia coli
2006
Tissue-Specific Inducible Expression of Antimicrobial Peptide Genes in Drosophila Surface Epithelia
2000 StandoutNobel
Supramolecular Hydrogelators and Hydrogels: From Soft Matter to Molecular Biomaterials
2015 Standout
Cyclization of a Cytolytic Amphipathic α-Helical Peptide and Its Diastereomer:  Effect on Structure, Interaction with Model Membranes, and Biological Function
2000
Nanozymes: Classification, Catalytic Mechanisms, Activity Regulation, and Applications
2019 Standout
Polysialic Acid, a Glycan with Highly Restricted Expression, Is Found on Human and Murine Leukocytes and Modulates Immune Responses
2008 StandoutNobel
Antibacterial Action of Structurally Diverse Cationic Peptides on Gram-Positive Bacteria
2000
Visualization of mycobacterial membrane dynamics in live cells
2017 StandoutNobel
The antimicrobial peptide SAAP-148 combats drug-resistant bacteria and biofilms
2018
Characterization of the hipA7 allele of Escherichia coli and evidence that high persistence is governed by (p)ppGpp synthesis
2003
Proteus mirabilis pmrI , an RppA-Regulated Gene Necessary for Polymyxin B Resistance, Biofilm Formation, and Urothelial Cell Invasion
2010
Experimental evolution of resistance to an antimicrobial peptide
2005
Bacterial Resistance to β-Lactam Antibiotics:  Compelling Opportunism, Compelling Opportunity
2005 Standout
PhoU Is a Persistence Switch Involved in Persister Formation and Tolerance to Multiple Antibiotics and Stresses in Escherichia coli
2007
Characterization of UDP-Glucose Dehydrogenase and UDP-Glucose Pyrophosphorylase Mutants ofProteus mirabilis: Defectiveness in Polymyxin B Resistance, Swarming, and Virulence
2010
β-Peptides:  From Structure to Function
2001 Standout
Riddle of Biofilm Resistance
2001 Standout
A PhoP-Regulated Outer Membrane Protease of Salmonella enterica Serovar Typhimurium Promotes Resistance to Alpha-Helical Antimicrobial Peptides
2000
Importance of the Membrane-Perturbing Properties of the Membrane-Proximal External Region of Human Immunodeficiency Virus Type 1 gp41 to Viral Fusion
2008
Imaging bacterial peptidoglycan with near-infrared fluorogenic azide probes
2014 StandoutNobel
Immunomodulatory Activities of Small Host Defense Peptides
2005
Complicated Catheter-Associated Urinary Tract Infections Due toEscherichia coliandProteus mirabilis
2008
Persisters: a distinct physiological state of E. coli.
2006
Role of RppA in the Regulation of Polymyxin B Susceptibility, Swarming, and Virulence Factor Expression in Proteus mirabilis
2008
Protegrin-1: a broad-spectrum, rapidly microbicidal peptide with in vivo activity
1997
Enhanced Antibacterial Potential in UBP43-Deficient Mice against Salmonella typhimurium Infection by Up-Regulating Type I IFN Signaling
2005 StandoutNobel
The importance of being proline: the interaction of proline‐rich motifs in signaling proteins with their cognate domains
2000
Antiendotoxin activity of cationic peptide antimicrobial agents
1996
Biofilm-Related Infections: Bridging the Gap between Clinical Management and Fundamental Aspects of Recalcitrance toward Antibiotics
2014 Standout
Identification of simple arylfluorosulfates as potent agents against resistant bacteria
2021 StandoutNobel
Mechanism of Interaction of Different Classes of Cationic Antimicrobial Peptides with Planar Bilayers and with the Cytoplasmic Membrane ofEscherichia coli
1999
Programmed Death in Bacteria
2000
Functional and Biochemical Analysis of Chlamydia trachomatis MurC, an Enzyme Displaying UDP- N -Acetylmuramate:Amino Acid Ligase Activity
2003
Capsule Polysaccharide Mediates Bacterial Resistance to Antimicrobial Peptides
2004
Structure−Activity Relation of Human β-Defensin 3:  Influence of Disulfide Bonds and Cysteine Substitution on Antimicrobial Activity and Cytotoxicity
2005
Pharmaceuticals of Emerging Concern in Aquatic Systems: Chemistry, Occurrence, Effects, and Removal Methods
2019 Standout
Biofilms and Planktonic Cells of Pseudomonas aeruginosa Have Similar Resistance to Killing by Antimicrobials
2001
Bacteria-Selective Synergism between the Antimicrobial Peptides α-Helical Magainin 2 and Cyclic β-Sheet Tachyplesin I:  Toward Cocktail Therapy
2001
Activatable Photosensitizers for Imaging and Therapy
2010 Standout
mig - 14 Is a Salmonella Gene That Plays a Role in Bacterial Resistance to Antimicrobial Peptides
2002
Interaction of Polyphemusin I and Structural Analogs with Bacterial Membranes, Lipopolysaccharide, and Lipid Monolayers
2000
Inherent Antibacterial Activity of a Peptide-Based β-Hairpin Hydrogel
2007
Killing by Ampicillin and Ofloxacin Induces Overlapping Changes in Escherichia coli Transcription Profile
2004
Molecular mechanisms of multiple toxin–antitoxin systems are coordinated to govern the persister phenotype
2013
Interaction and Cellular Localization of the Human Host Defense Peptide LL-37 with Lung Epithelial Cells
2004
Large mutational target size for rapid emergence of bacterial persistence
2012
The plasma membrane of Leishmania donovani promastigotes is the main target for CA(1–8)M(1–18), a synthetic cecropin A–melittin hybrid peptide
1998
Lack of Cell Wall Peptidoglycan versus Penicillin Sensitivity: New Insights into the Chlamydial Anomaly
1999
A Fluorogenic Trehalose Probe for Tracking Phagocytosed Mycobacterium tuberculosis
2020 StandoutNobel
Involvement of pmrAB and phoPQ in Polymyxin B Adaptation and Inducible Resistance in Non-Cystic Fibrosis Clinical Isolates of Pseudomonas aeruginosa
2009
Acute Modulation of Mycobacterial Cell Envelope Biogenesis by Front‐Line Tuberculosis Drugs
2018 StandoutNobel
Dormancy Is Not Necessary or Sufficient for Bacterial Persistence
2013
Phylogenetic Perspectives in Innate Immunity
1999 StandoutScienceNobel
Role of Pseudomonas aeruginosa PhoP-PhoQ in resistance to antimicrobial cationic peptides and aminoglycosides
2000
Persister Cells
2010
Structure of the Bovine Antimicrobial Peptide Indolicidin Bound to Dodecylphosphocholine and Sodium Dodecyl Sulfate Micelles,
2000
Structure-Based Design of an Indolicidin Peptide Analogue with Increased Protease Stability,
2003
Induced resistance to the antimicrobial peptide lactoferricin B in Staphylococcus aureus
2005
Human parvovirus B19 as a causative agent for rheumatoid arthritis
1998
Salt-Resistant Alpha-Helical Cationic Antimicrobial Peptides
1999
Peptide Antibiotics
1999

Works of Timothy J. Falla being referenced

Cationic Bactericidal Peptides
1995
Mode of Action of the Antimicrobial Peptide Indolicidin
1996
Determinants of Recombinant Production of Antimicrobial Cationic Peptides and Creation of Peptide Variants in Bacteria
1998
HB‐107, a nonbacteriostatic fragment of the antimicrobial peptide cecropin B, accelerates murine wound repair
2004
Development of protegrins for the treatment and prevention of oral mucositis: Structure-activity relationships of synthetic protegrin analogues
2000
Antimicrobial peptides: therapeutic potential
2006
Antimicrobial peptides: broad-spectrum antibiotics from nature
1996
Population-based study of non-typable Haemophilus influenzae invasive disease in children and neonates
1993
PCR for capsular typing of Haemophilus influenzae
1994
Improved activity of a synthetic indolicidin analog
1997
Identification of Proteus mirabilis Mutants with Increased Sensitivity to Antimicrobial Peptides
2001
IB-367, a Protegrin Peptide with In Vitro and In Vivo Activities against the Microflora Associated with Oral Mucositis
2000
Joint Tolerance to β-Lactam and Fluoroquinolone Antibiotics in Escherichia coli Results from Overexpression of hipA
1998
Antibiotics, peptidoglycan synthesis and genomics: the chlamydial anomaly revisited
1998
Antimicrobial Peptide Therapeutics for Cystic Fibrosis
2005
Cationic antimicrobial peptides – an update
2004
Stabilization of Rhizobium symbiosis plasmids
1999
Rankless by CCL
2026