Citation Impact
Citing Papers
Generation of ordered protein assemblies using rigid three-body fusion
2021 StandoutNobel
DNA capture by a CRISPR-Cas9–guided adenine base editor
2020 StandoutScienceNobel
Structures of a CRISPR-Cas9 R-loop complex primed for DNA cleavage
2016 StandoutScienceNobel
De novo design of self-assembling helical protein filaments
2018 StandoutScienceNobel
Structure of the human TRPM4 ion channel in a lipid nanodisc
2017 StandoutScienceNobel
Structures of the CRISPR genome integration complex
2017 StandoutScienceNobel
Hallucinating symmetric protein assemblies
2022 StandoutScienceNobel
Accurate computational design of multipass transmembrane proteins
2018 StandoutScienceNobel
De novo design of picomolar SARS-CoV-2 miniprotein inhibitors
2020 StandoutScienceNobel
Structural basis for the recognition of SARS-CoV-2 by full-length human ACE2
2020 StandoutScience
Structure of the human epithelial sodium channel by cryo-electron microscopy
2018
Frealign
2016
Four-component protein nanocages designed by programmed symmetry breaking
2024 StandoutNatureNobel
Hierarchical design of pseudosymmetric protein nanocages
2024 StandoutNatureNobel
Assembly of complex viruses exemplified by a halophilic euryarchaeal virus
2019
Target-conditioned diffusion generates potent TNFR superfamily antagonists and agonists
2024 StandoutScienceNobel
The ϕPA3 phage nucleus is enclosed by a self-assembling 2D crystalline lattice
2023 StandoutNobel
Computational design of soluble and functional membrane protein analogues
2024 StandoutNatureNobel
De novo design of allosterically switchable protein assemblies
2024 StandoutNatureNobel
Engineered receptors for soluble cellular communication and disease sensing
2024 StandoutNatureNobel
Structural Basis for Gating and Activation of RyR1
2016 StandoutNobel
Unravelling biological macromolecules with cryo-electron microscopy
2016 Nature
Discoveries in structure and physiology of mechanically activated ion channels
2020 StandoutNatureNobel
cryoSPARC: algorithms for rapid unsupervised cryo-EM structure determination
2017 Standout
Structural biology of glutamate receptor ion channel complexes
2016
A Bayesian approach to beam-induced motion correction in cryo-EM single-particle analysis
2018
Real-time cryo-electron microscopy data preprocessing with Warp
2019 Standout
MotionCor2: anisotropic correction of beam-induced motion for improved cryo-electron microscopy
2017 Standout
Non-uniform refinement: adaptive regularization improves single-particle cryo-EM reconstruction
2020 Standout
Channel opening and gating mechanism in AMPA-subtype glutamate receptors
2017 StandoutNatureNobel
Evaluating Local and Directional Resolution of Cryo-EM Density Maps
2020
Irritant-evoked activation and calcium modulation of the TRPA1 receptor
2020 StandoutNatureNobel
Resting-State Structure and Gating Mechanism of a Voltage-Gated Sodium Channel
2019
De novo design of luciferases using deep learning
2023 StandoutNatureNobel
Cryo-EM structure of the protein-conducting ERAD channel Hrd1 in complex with Hrd3
2017 StandoutNatureNobel
Asynchronous data acquisition and on-the-fly analysis of dose fractionated cryoEM images by UCSFImage
2015
Enhanced proofreading governs CRISPR–Cas9 targeting accuracy
2017 StandoutNatureNobel
Cryo-EM structures of fungal and metazoan mitochondrial calcium uniporters
2018 Nature
A Broad-Spectrum Inhibitor of CRISPR-Cas9
2017 StandoutNobel
Retrieving high-resolution information from disordered 2D crystals by single-particle cryo-EM
2019
A Cell-Penetrating Scorpion Toxin Enables Mode-Specific Modulation of TRPA1 and Pain
2019 StandoutNobel
Structure of the mechanically activated ion channel Piezo1
2017 StandoutNatureNobel
TRPV1 structures in nanodiscs reveal mechanisms of ligand and lipid action
2016 StandoutNatureNobel
Structural snapshots of TRPV1 reveal mechanism of polymodal functionality
2021 StandoutNobel
Human TRPML1 channel structures in open and closed conformations
2017 NatureNobel
3D variability analysis: Resolving continuous flexibility and discrete heterogeneity from single particle cryo-EM
2021
In vivo phosphorylation patterns of key stressosome proteins define a second feedback loop that limits activation of Bacillus subtilisσB
2011
Real-space refinement in PHENIX for cryo-EM and crystallography
2018 Standout
The Biology of CRISPR-Cas: Backward and Forward
2018 StandoutNobel
Structural Bases of Desensitization in AMPA Receptor-Auxiliary Subunit Complexes
2017 StandoutNobel
CasX enzymes comprise a distinct family of RNA-guided genome editors
2019 StandoutNatureNobel
Structure Basis for Directional R-loop Formation and Substrate Handover Mechanisms in Type I CRISPR-Cas System
2017
Architecture of the TRPM2 channel and its activation mechanism by ADP-ribose and calcium
2018 Nature
Cryo-EM Structure of a KCNQ1/CaM Complex Reveals Insights into Congenital Long QT Syndrome
2017 Nobel
Structure of the hyperosmolality-gated calcium-permeable channel OSCA1.2
2018
Cryo-EM structure of a type IV secretion system
2022 StandoutNatureNobel
Alternate binding modes of anti-CRISPR viral suppressors AcrF1/2 to Csy surveillance complex revealed by cryo-EM structures
2017
Elucidation of AMPA receptor–stargazin complexes by cryo–electron microscopy
2016 StandoutScienceNobel
Structure of the STRA6 receptor for retinol uptake
2016 StandoutScienceNobel
The 3.1-Angstrom Cryo-electron Microscopy Structure of the Porcine Epidemic Diarrhea Virus Spike Protein in the Prefusion Conformation
2019
Guidelines for using Bsoft for high resolution reconstruction and validation of biomolecular structures from electron micrographs
2017
Osmosensory signaling in Mycobacterium tuberculosis mediated by a eukaryotic-like Ser/Thr protein kinase
2013 StandoutNobel
Architecture of fully occupied GluA2 AMPA receptor–TARP complex elucidated by cryo-EM
2016 Nature
Cryo-EM structure of the 2019-nCoV spike in the prefusion conformation
2020 StandoutScience
Entropy-regularized deconvolution of cellular cryotransmission electron tomograms
2021
Structure of mouse protocadherin 15 of the stereocilia tip link in complex with LHFPL5
2018
Computational design of mechanically coupled axle-rotor protein assemblies
2022 StandoutScienceNobel
New tools for automated high-resolution cryo-EM structure determination in RELION-3
2018 Standout
Accelerated cryo-EM structure determination with parallelisation using GPUs in RELION-2
2016 Standout
Structural insight into TRPV5 channel function and modulation
2019 StandoutNobel
Top-down design of protein architectures with reinforcement learning
2023 StandoutScienceNobel
Structural insights into TRPM8 inhibition and desensitization
2019 StandoutScienceNobel
Reconfigurable asymmetric protein assemblies through implicit negative design
2022 StandoutScienceNobel
Works of Timothy Grant being referenced
Activation of NMDA receptors and the mechanism of inhibition by ifenprodil
2016 Nature
Structure of the L Protein of Vesicular Stomatitis Virus from Electron Cryomicroscopy
2015
Automatic estimation and correction of anisotropic magnification distortion in electron microscopes
2015
Molecular Architecture of the "Stressosome," a Signal Integration and Transduction Hub
2008 Science
Mechanism of ribosome rescue by ArfA and RF2
2017
Measuring the optimal exposure for single particle cryo-EM using a 2.6 Å reconstruction of rotavirus VP6
2015
cisTEM, user-friendly software for single-particle image processing
2018
Ensemble cryo-EM uncovers inchworm-like translocation of a viral IRES through the ribosome
2016