Standout Papers
Citation Impact
Citing Papers
A Membrane Receptor for Retinol Binding Protein Mediates Cellular Uptake of Vitamin A
2007 Science
Insulin-sensitive obesity
2010
Metabolic Syndrome and Altered Gut Microbiota in Mice Lacking Toll-Like Receptor 5
2010 StandoutScience
Sex Differences in the Gut Microbiome Drive Hormone-Dependent Regulation of Autoimmunity
2013 StandoutScience
Transthyretin: a multifaceted protein
2014
The STRA6 Receptor Is Essential for Retinol-binding Protein-induced Insulin Resistance but Not for Maintaining Vitamin A Homeostasis in Tissues Other Than the Eye
2013
WGCNA: an R package for weighted correlation network analysis
2008 Standout
Bone-marrow adipocytes as negative regulators of the haematopoietic microenvironment
2009 Nature
The secretory function of adipocytes in the physiology of white adipose tissue
2008
Ceramides as modulators of cellular and whole-body metabolism
2011
Molecular mechanisms of GLUT4 regulation in adipocytes
2014
Adipose tissue heterogeneity: Implication of depot differences in adipose tissue for obesity complications
2012
MCP-1 contributes to macrophage infiltration into adipose tissue, insulin resistance, and hepatic steatosis in obesity
2006 Standout
S-Nitrosothiols modulate G protein-coupled receptor signaling in a reversible and highly receptor-specific manner
2005
Inflammation and metabolic disorders
2006 StandoutNature
Adipose Tissue Branched Chain Amino Acid (BCAA) Metabolism Modulates Circulating BCAA Levels
2010
Increased adipose tissue expression of lipocalin-2 in obesity is related to inflammation and matrix metalloproteinase-2 and metalloproteinase-9 activities in humans
2009
NMDA Receptor-Nitric Oxide Transmission Mediates Neuronal Iron Homeostasis via the GTPase Dexras1
2006
Dietary emulsifiers impact the mouse gut microbiota promoting colitis and metabolic syndrome
2015 StandoutNature
Fecal Lipocalin 2, a Sensitive and Broadly Dynamic Non-Invasive Biomarker for Intestinal Inflammation
2012
Dynamics of fat cell turnover in humans
2008 StandoutNature
Control of Metabolic Homeostasis by Stress Signaling Is Mediated by the Lipocalin NLaz
2009
Mechanisms linking obesity with cardiovascular disease
2006 StandoutNature
The genetics of ageing
2010 StandoutNature
Activation of a Mitogen-activated Protein Kinase (ERK2) by the 5-Hydroxytryptamine1A Receptor Is Sensitive Not Only to Inhibitors of Phosphatidylinositol 3-Kinase, but to an Inhibitor of Phosphatidylcholine Hydrolysis
1996
RBP4 Activates Antigen-Presenting Cells, Leading to Adipose Tissue Inflammation and Systemic Insulin Resistance
2014
β-Arrestin-biased Agonism at the β2-Adrenergic Receptor
2007 StandoutNobel
A novel ChREBP isoform in adipose tissue regulates systemic glucose metabolism
2012 Nature
Identification of a novel distal enhancer in human adiponectin gene
2008
Adipocytes as regulators of energy balance and glucose homeostasis
2006 StandoutNature
Vitamin A Transport and the Transmembrane Pore in the Cell-Surface Receptor for Plasma Retinol Binding Protein
2013
Machine learning for molecular and materials science
2018 StandoutNature
Subcutaneous and Visceral Adipose Tissue Gene Expression of Serum Adipokines That Predict Type 2 Diabetes
2009
Homeostasis, Inflammation, and Disease Susceptibility
2015
A Single-Cell Transcriptome Atlas of the Human Pancreas
2016
Human nutrition, the gut microbiome and the immune system
2011 StandoutNature
Macrophage-specific PPARγ controls alternative activation and improves insulin resistance
2007 StandoutNature
STRA6 is critical for cellular vitamin A uptake and homeostasis
2014
Thrombin signalling and protease-activated receptors
2000 StandoutNature
RBP4: a controversial adipokine
2011
TLR4 links innate immunity and fatty acid–induced insulin resistance
2006 Standout
A unique chromatin signature uncovers early developmental enhancers in humans
2010 StandoutNature
Adipokines in inflammation and metabolic disease
2011 Standout
Regulation of β-Adrenergic Receptor Signaling by S-Nitrosylation of G-Protein-Coupled Receptor Kinase 2
2007 StandoutNobel
Molecular and metabolic mechanisms of insulin resistance and β-cell failure in type 2 diabetes
2008
Ferroptosis: An Iron-Dependent Form of Nonapoptotic Cell Death
2012 Standout
Functional interactions between the gut microbiota and host metabolism
2012 StandoutNature
Tissue-specific Alterations of Glucose Transport and Molecular Mechanisms of Intertissue Communication in Obesity and Type 2 Diabetes
2007
STRA6-Catalyzed Vitamin A Influx, Efflux, and Exchange
2012
Roles of Diacylglycerols and Ceramides in Hepatic Insulin Resistance
2017
The GLUT4 Glucose Transporter
2007
Macrophages are Novel Sites of Expression and Regulation of RetinolBinding Protein-4 (RBP4)
2010
Mechanisms linking obesity to insulin resistance and type 2 diabetes
2006 StandoutNature
Expression, characterization and ligand specificity of lipocalin-1 interacting membrane receptor (LIMR)
2013
Anti-diabetic drugs inhibit obesity-linked phosphorylation of PPARγ by Cdk5
2010 Nature
Macrophages block insulin action in adipocytes by altering expression of signaling and glucose transport proteins
2006
Retinol Binding Protein 4 Stimulates Hepatic Sterol Regulatory Element-Binding Protein 1 and Increases Lipogenesis Through the Peroxisome Proliferator-Activated Receptor-γ Coactivator 1β-Dependent Pathway
2013
Origin and physiological roles of inflammation
2008 StandoutNature
G-protein signaling: back to the future
2005
Mechanisms of fatty acid-induced inhibition of glucose uptake.
1994 Standout
Serotonin 5-HT1A Receptor-mediated Erk Activation Requires Calcium/Calmodulin-dependent Receptor Endocytosis
1999 StandoutNobel
Genetics and pathogenesis of inflammatory bowel disease
2011 StandoutNature
Network-Based Analysis of Affected Biological Processes in Type 2 Diabetes Models
2007
What We Talk About When We Talk About Fat
2014 Standout
Receptor-Mediated Cellular Uptake Mechanism That Couples to Intracellular Storage
2011
Application of text mining in the biomedical domain
2015
Macrophage biology in development, homeostasis and disease
2013 StandoutNature
Reconstitution of Receptors and GTP-binding Regulatory Proteins (G Proteins) in Sf9 Cells
1997
Serum retinol binding protein 4 level is related with renal functions in Type 2 diabetes
2010
Positive and Negative Regulation of Insulin Signaling by Reactive Oxygen and Nitrogen Species
2009
Transplantation of adipose tissue and stem cells: role in metabolism and disease
2010
High Sugar-Induced Insulin Resistance in Drosophila Relies on the Lipocalin Neural Lazarillo
2012
Inflammation, metaflammation and immunometabolic disorders
2017 StandoutNature
Comprehensive Integration of Single-Cell Data
2019 Standout
Allosteric Effects of G Protein Overexpression on the Binding of β-Adrenergic Ligands with Distinct Inverse Efficacies
2001
RBP4 Disrupts Vitamin A Uptake Homeostasis in a STRA6-Deficient Animal Model for Matthew-Wood Syndrome
2008
Adipocytokines: mediators linking adipose tissue, inflammation and immunity
2006 Standout
Single-Cell Transcriptome Profiling of Human Pancreatic Islets in Health and Type 2 Diabetes
2016
Retinaldehyde dehydrogenase 1 regulates a thermogenic program in white adipose tissue
2012
LRG1 promotes angiogenesis by modulating endothelial TGF-β signalling
2013 StandoutNature
Nicotinamide N-methyltransferase knockdown protects against diet-induced obesity
2014 Nature
Adiponectin and adiponectin receptors in insulin resistance, diabetes, and the metabolic syndrome
2006 Standout
Mechanisms of Insulin Action and Insulin Resistance
2018 Standout
Structure of the STRA6 receptor for retinol uptake
2016 StandoutScienceNobel
Ras-Dependent Activation of Fibroblast Mitogen-Activated Protein Kinase by 5-HT1A Receptor via a G Protein βγ-Subunit-Initiated Pathway
1996 StandoutNobel
Myocardial Fatty Acid Metabolism in Health and Disease
2010 Standout
Adipose Tissue
2006
Serum Retinol-Binding Protein-4, Leptin, and Adiponectin Concentrations Are Related to Ectopic Fat Accumulation
2007
β-Arrestin-Dependent Formation of β 2 Adrenergic Receptor-Src Protein Kinase Complexes
1999 StandoutScienceNobel
Interactions Between the Microbiota and the Immune System
2012 StandoutScience
Combined Proteomic and Metabolomic Profiling of Serum Reveals Association of the Complement System with Obesity and Identifies Novel Markers of Body Fat Mass Changes
2011
Lipocalin-2 Is an Inflammatory Marker Closely Associated with Obesity, Insulin Resistance, and Hyperglycemia in Humans
2006
Endocrine Functions of Adipose Tissue
2006
A minor role for lipocalin 2 in high-fat diet-induced glucose intolerance
2011
The role of skeletal muscle insulin resistance in the pathogenesis of the metabolic syndrome
2007
Identification of the retinol‐binding protein (RBP) interaction site and functional state of RBPs for the membrane receptor
2007
Impaired insulin secretion and glucose intolerance in synaptotagmin-7 null mutant mice
2008 StandoutNobel
Characterization of the Vitreous Proteome in Diabetes without Diabetic Retinopathy and Diabetes with Proliferative Diabetic Retinopathy
2008
Spermidine in health and disease
2018 StandoutScience
The multifaceted nature of retinoid transport and metabolism.
2014
Lipocalin-2 Deficiency Attenuates Insulin Resistance Associated With Aging and Obesity
2010
Retinol‐binding protein‐4 attenuates insulin‐induced phosphorylation of IRS1 and ERK1/2 in primary human adipocytes
2007
The biology , function , and biomedical applications of exosomes
2020 StandoutScience
Sphingolipids, Insulin Resistance, and Metabolic Disease: New Insights from in Vivo Manipulation of Sphingolipid Metabolism
2008
Inflammatory Mechanisms in Obesity
2011 Standout
The Role of Lipocalin 2 in the Regulation of Inflammation in Adipocytes and Macrophages
2008
Hypoxia and Adipose Tissue Function and Dysfunction in Obesity
2013
An endocrine role for brown adipose tissue?
2013
Diabetic Neuropathy: A Position Statement by the American Diabetes Association
2016 Standout
Fenretinide Derivatives Act as Disrupters of Interactions of Serum Retinol Binding Protein (sRBP) with Transthyretin and the sRBP Receptor
2011
The effect of ligand efficacy on the formation and stability of a GPCR-G protein complex
2009 StandoutNobel
Lipocalin-2 Deficiency Impairs Thermogenesis and Potentiates Diet-Induced Insulin Resistance in Mice
2010
Macrophages, Inflammation, and Insulin Resistance
2010 Standout
Rapid activation of sodium–proton exchange and extracellular signal-regulated protein kinase in fibroblasts by G protein-coupled 5-HT1A receptor involves distinct signalling cascades
1998
Evidence That Kidney Function but Not Type 2 Diabetes Determines Retinol-Binding Protein 4 Serum Levels
2008
Adipose Tissue Exosome-Like Vesicles Mediate Activation of Macrophage-Induced Insulin Resistance
2009
Mitochondrial Dysfunction in the Elderly: Possible Role in Insulin Resistance
2003 StandoutScience
Cross Talk between Signaling and Vitamin A Transport by the Retinol-Binding Protein Receptor STRA6
2012
Retinol-Binding Protein 4 Inhibits Insulin Signaling in Adipocytes by Inducing Proinflammatory Cytokines in Macrophages through a c-Jun N-Terminal Kinase- and Toll-Like Receptor 4-Dependent and Retinol-Independent Mechanism
2012
Signaling by vitamin A and retinol-binding protein regulates gene expression to inhibit insulin responses
2011
Works of Timothy E. Graham being referenced
High circulating levels of RBP4 and mRNA levels of aP2, PGC‐1α and UCP‐2 predict improvement in insulin sensitivity following pioglitazone treatment of drug‐naïve type 2 diabetic subjects
2008
Dexras1/AGS-1 Inhibits Signal Transduction from the Gi-coupled Formyl Peptide Receptor to Erk-1/2 MAP Kinases
2002
Serum Retinol-Binding Protein Is More Highly Expressed in Visceral than in Subcutaneous Adipose Tissue and Is a Marker of Intra-abdominal Fat Mass
2007
Retinol-Binding Protein 4 and Insulin Resistance in Lean, Obese, and Diabetic Subjects
2006
Expression of the Human 5-Hydroxytryptamine1A Receptor in Sf9 Cells
1995
Shortcomings in methodology complicate measurements of serum retinol binding protein (RBP4) in insulin-resistant human subjects
2007
Serum retinol binding protein 4 contributes to insulin resistance in obesity and type 2 diabetes
2005 StandoutNature
Liver Retinol Transporter and Receptor for Serum Retinol-binding Protein (RBP4)
2012
Decreased clearance of serum retinol-binding protein and elevated levels of transthyretin in insulin-resistantob/obmice
2008
The Relationship of Retinol Binding Protein 4 to Changes in Insulin Resistance and Cardiometabolic Risk in Overweight Black Adolescents
2008
Dexras1 inhibits adenylyl cyclase
2004
Dexras1/AGS-1, a Steroid Hormone-Induced Guanosine Triphosphate-Binding Protein, Inhibits 3′,5′-Cyclic Adenosine Monophosphate-Stimulated Secretion in AtT-20 Corticotroph Cells1
2001
Quantitative Measurement of Full-Length and C-Terminal Proteolyzed RBP4 in Serum of Normal and Insulin-Resistant Humans using a Novel Mass Spectrometry Immunoassay
2012
The Adipokine Lipocalin 2 Is Regulated by Obesity and Promotes Insulin Resistance
2007
Hepatocytes Are the Principal Source of Circulating RBP4 in Mice
2016
Reduction of Elevated Serum Retinol Binding Protein in Obese Children by Lifestyle Intervention: Association with Subclinical Inflammation
2007
Long-term Fenretinide treatment prevents high-fat diet-induced obesity, insulin resistance, and hepatic steatosis
2009
Effects of Genetic Variation in the Human Retinol Binding Protein-4 Gene (RBP4) on Insulin Resistance and Fat Depot–Specific mRNA Expression
2007
Exercise increases cutaneous nerve density in diabetic patients without neuropathy
2014