Citation Impact
Citing Papers
Histone demethylase KDM6A directly senses oxygen to control chromatin and cell fate
2019 StandoutScienceNobel
Multiple Antitumor Mechanisms Downstream of Prophylactic Regulatory T-Cell Depletion
2010 StandoutNobel
PD-1 + regulatory T cells amplified by PD-1 blockade promote hyperprogression of cancer
2019 StandoutNobel
Treatment of kidney cancer
2009 StandoutNobel
Hallmarks of Cancer: The Next Generation
2011 Standout
Immunotherapy of cancer in 2012
2012
Platelet factor 4–induced T H 1-T reg polarization suppresses antitumor immunity
2024 StandoutScienceNobel
Hypoxia-Inducible Factor Linked to Differential Kidney Cancer Risk Seen with Type 2A and Type 2B VHL Mutations
2007 StandoutNobel
Functional diversity of helper T lymphocytes
1996 StandoutNature
Mechanism of activation of the TGF-β receptor
1994 StandoutNature
Bioorthogonal Chemistry: Fishing for Selectivity in a Sea of Functionality
2009 StandoutNobel
The von Hippel–Lindau tumour suppressor protein: O2 sensing and cancer
2008 StandoutNobel
Synthesis and biological study of a flavone acetic acid analogue containing an azido reporting group designed as a multifunctional binding site probe
2005
Combining immunotherapy and targeted therapies in cancer treatment
2012
Melanin Pigmentation in Mammalian Skin and Its Hormonal Regulation
2004 Standout
Unravelling the pathogenesis of inflammatory bowel disease
2007 StandoutNature
Transforming growth factor beta (TGF-?) in inflammation: A cause and a cure
1992
TGF-β signalling from cell membrane to nucleus through SMAD proteins
1997 StandoutNature
Elite and stochastic models for induced pluripotent stem cell generation
2009 StandoutNatureNobel
The von Hippel‐Lindau Tumor Suppressor Protein: An Update
2007 StandoutNobel
HIF2α cooperates with RAS to promote lung tumorigenesis in mice
2009 StandoutNobel
Renal-Cell Carcinoma
1996 Standout
Transforming growth factor beta 1 suppresses acute and chronic arthritis in experimental animals.
1991
Functional polarization of tumour-associated macrophages by tumour-derived lactic acid
2014 StandoutNature
The Hallmarks of Cancer
2000 Standout
The T/E1A-binding domain of the retinoblastoma product can interact selectively with a sequence-specific DNA-binding protein
1991 StandoutNobel
KLF4, p21 and context-dependent opposing forces in cancer
2005
Transforming growth factor-β induces development of the TH17 lineage
2006 StandoutNature
Inhibitory B7-family molecules in the tumour microenvironment
2008
Immune-mediated mechanisms influencing the efficacy of anticancer therapies
2015
Failure to prolyl hydroxylate hypoxia‐inducible factor α phenocopies VHL inactivation in vivo
2006 StandoutNobel
Alternative Activation of Macrophages: Mechanism and Functions
2010 Standout
Exosomes facilitate therapeutic targeting of oncogenic KRAS in pancreatic cancer
2017 StandoutNature
Targeted disruption of the mouse transforming growth factor-β1 gene results in multifocal inflammatory disease
1992 StandoutNature
Points of control in inflammation
2002 StandoutNature
Macrophage biology in development, homeostasis and disease
2013 StandoutNature
Oxygen Sensing, Homeostasis, and Disease
2011 StandoutNobel
Co-evolution of tumor cells and their microenvironment
2008
Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan
2003 StandoutNature
EGLN1 Inhibition and Rerouting of α-Ketoglutarate Suffice for Remote Ischemic Protection
2016 StandoutNobel
The pathogenesis of atherosclerosis: a perspective for the 1990s
1993 StandoutNature
Combination immunotherapy: a road map
2017
TGF-β stimulation and inhibition of cell proliferation: New mechanistic insights
1990 Standout
Autochthonous tumors driven by Rb1 loss have an ongoing requirement for the RBP2 histone demethylase
2018 StandoutNobel
Cancer dormancy. VII. A regulatory role for CD8+ T cells and IFN-gamma in establishing and maintaining the tumor-dormant state.
1999
The Von Hippel-Lindau Tumor Suppressor Gene and Kidney Cancer
2004 StandoutNobel
von Hippel-Lindau Disease
2006 StandoutNobel
Recruitment of monocytes/macrophages by tissue factor-mediated coagulation is essential for metastatic cell survival and premetastatic niche establishment in mice
2012
Lack of a role for transforming growth factor-β in cytotoxic T lymphocyte antigen-4-mediated inhibition of T cell activation
2001 StandoutNobel
Cancer Immunoediting: Integrating Immunity’s Roles in Cancer Suppression and Promotion
2011 StandoutScience
EglN3 hydroxylase stabilizes BIM-EL linking VHL type 2C mutations to pheochromocytoma pathogenesis and chemotherapy resistance
2019 StandoutNobel
A Feedback Loop Involving the Phd3 Prolyl Hydroxylase Tunes the Mammalian Hypoxic Response In Vivo
2009 StandoutNobel
IL-27 gene therapy induces depletion of Tregs and enhances the efficacy of cancer immunotherapy
2018
Kinase requirements in human cells: III. Altered kinase requirements inVHL−/− cancer cells detected in a pilot synthetic lethal screen
2008 StandoutNobel
Chemotherapy induces enrichment of CD47 + /CD73 + /PDL1 + immune evasive triple-negative breast cancer cells
2018 StandoutNobel
Reactivation of Hepatic EPO Synthesis in Mice After PHD Loss
2010 StandoutScienceNobel
pVHL suppresses kinase activity of Akt in a proline-hydroxylation–dependent manner
2016 StandoutScienceNobel
TGF-β1 inhibition of c-myc transcription and growth in keratinocytes is abrogated by viral transforming proteins with pRB binding domains
1990
Somatic inactivation of the PHD2 prolyl hydroxylase causes polycythemia and congestive heart failure
2007 StandoutNobel
The Effects of Plant Flavonoids on Mammalian Cells:Implications for Inflammation, Heart Disease, and Cancer
2000 Standout
Cancer Genome Landscapes
2013 StandoutScience
Precision glycocalyx editing as a strategy for cancer immunotherapy
2016 StandoutNobel
Transforming growth factor beta 1 null mutation in mice causes excessive inflammatory response and early death.
1993 Standout
Antitumor and antimetastatic activity of interleukin 12 against murine tumors.
1993
The von Hippel-Lindau Tumor Suppressor Protein and Clear Cell Renal Carcinoma
2007 StandoutNobel
Genetics and biology of pancreatic ductal adenocarcinoma
2016
Discovery and Biology of IL-23 and IL-27: Related but Functionally Distinct Regulators of Inflammation
2006
Inhibition of the oxygen sensor PHD2 in the liver improves survival in lactic acidosis by activating the Cori cycle
2015 StandoutNobel
Works of Timothy Back being referenced
Nitric Oxide Is a Key Component in Inflammation-Accelerated Tumorigenesis
2008
mTOR Kinase Inhibitor AZD8055 Enhances the Immunotherapeutic Activity of an Agonist CD40 Antibody in Cancer Treatment
2011
IL-27 Mediates Complete Regression of Orthotopic Primary and Metastatic Murine Neuroblastoma Tumors: Role for CD8+ T Cells
2004
Macrophage migration inhibitory factor induces epithelial to mesenchymal transition, enhances tumor aggressiveness and predicts clinical outcome in resected pancreatic ductal adenocarcinoma
2012
Administration of Interleukin 12 With Pulse Interleukin 2 and the Rapid and Complete Eradication of Murine Renal Carcinoma
1996
IFN-γ mediates CD4+ T-cell loss and impairs secondary antitumor responses after successful initial immunotherapy
2007
Flavone-8-acetic acid augments systemic natural killer cell activity and synergizes with IL-2 for treatment of murine renal cancer.
1988
Augmentation of natural killer activity, induction of IFN and development tumor immunity during the successful treatment of established murine renal cancer using flavone acetic acid and IL-2.
1988
Mice with a targeted mutation in lymphotoxin-alpha exhibit enhanced tumor growth and metastasis: impaired NK cell development and recruitment.
1999
Enhanced Antitumor Response by Divergent Modulation of Natural Killer and Natural Killer T Cells in the Liver
2006
Hepatic vascular tumors, angiectasis in multiple organs, and impaired spermatogenesis in mice with conditional inactivation of the VHL gene.
2003
Synergistic Anti-Tumor Responses After Administration of Agonistic Antibodies to CD40 and IL-2: Coordination of Dendritic and CD8+ Cell Responses
2003
Successful immunotherapy with IL-2/anti-CD40 induces the chemokine-mediated mitigation of an immunosuppressive tumor microenvironment
2009
Immunologic and Therapeutic Synergy of IL-27 and IL-2: Enhancement of T Cell Sensitization, Tumor-Specific CTL Reactivity and Complete Regression of Disseminated Neuroblastoma Metastases in the Liver and Bone Marrow
2009
Inhibition of early murine hemopoietic progenitor cell proliferation after in vivo locoregional administration of transforming growth factor-beta 1.
1989
Successful treatment of advanced murine renal cell cancer by bicompartmental adoptive chemoimmunotherapy.
1987
Tumor-Specific CTL Kill Murine Renal Cancer Cells Using Both Perforin and Fas Ligand-Mediated Lysis In Vitro, But Cause Tumor Regression In Vivo in the Absence of Perforin
2002
Interleukin 12 primes macrophages for nitric oxide production in vivo and restores depressed nitric oxide production by macrophages from tumor-bearing mice: implications for the antitumor activity of interleukin 12 and/or interleukin 2.
1996
In Vivo Regulation of Experimental Autoimmune Encephalomyelitis by NK Cells: Alteration of Primary Adaptive Responses
2008