Citation Impact
Citing Papers
Serotonin Transporter Genetic Variation and the Response of the Human Amygdala
2002 StandoutScience
Catechol‐o‐methyltransferase (COMT) and proline dehydrogenase (PRODH) mRNAs in the dorsolateral prefrontal cortex in schizophrenia, bipolar disorder, and major depression
2003
A biomolecular force field based on the free enthalpy of hydration and solvation: The GROMOS force‐field parameter sets 53A5 and 53A6
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Understanding adolescence as a period of social–affective engagement and goal flexibility
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Neurobehavioral evidence for changes in dopamine system activity during adolescence
2009
Genetic and Neurochemical Modulation of Prefrontal Cognitive Functions in Children
2003
Functional Analysis of Genetic Variation in Catechol-O-Methyltransferase (COMT): Effects on mRNA, Protein, and Enzyme Activity in Postmortem Human Brain
2004
Okey Lecture 2006: identifying the neurobiological mechanisms of addictive behaviour*
2007
Stress-Related Methylation of the Catechol- O -Methyltransferase Val 158 Allele Predicts Human Prefrontal Cognition and Activity
2011
Catechol O-methyltransferase mRNA expression in human and rat brain: evidence for a role in cortical neuronal function
2003
Adverse Health Effects of Marijuana Use
2014 Standout
Genetic basis for individual variations in pain perception and the development of a chronic pain condition
2004 Standout
Association of the G1947A COMT (Val108/158Met) gene polymorphism with prefrontal P300 during information processing
2003
The T-box factor MLS-1 acts as a molecular switch during specification of nonstriated muscle in C. elegans
2002 StandoutNobel
Ultradian rapid cycling in prepubertal and early adolescent bipolarity is not in transmission disequilibrium with val/met COMT alleles
2000
Population variation in linkage disequilibrium across the COMT gene considering promoter region and coding region variation
2002
Catechol- O -methyltransferase gene polymorphisms are associated with multiple pain-evoking stimuli
2006
Oral Anticoagulant Therapy
2012 Standout
Using genetic data in cognitive neuroscience: from growing pains to genuine insights
2008
Catechol-O-Methyltransferase Inhibition Improves Set-Shifting Performance and Elevates Stimulated Dopamine Release in the Rat Prefrontal Cortex
2004
Phaeochromocytoma
2005 Standout
Understanding Catecholamine Metabolism as a Guide to the Biochemical Diagnosis of Pheochromocytoma
2001
Identification of Sequence Variants and Analysis of the Role of the Catechol-O-Methyl-Transferase Gene in Schizophrenia Susceptibility
1998
The ground state of embryonic stem cell self-renewal
2008 StandoutNature
Human catechol O-methyltransferase genetic variation: gene resequencing and functional characterization of variant allozymes
2004
Metabolite profiles of two [14C]-labelled catechol O-methyltransferase inhibitors, nitecapone and entacapone, in rat and mouse urine and rat bile
1994
Global variation in the frequencies of functionally different catechol-O-methyltransferase alleles
1999
Family‐based and case‐control association studies of catechol‐O‐methyltransferase in attention deficit hyperactivity disorder suggest genetic sexual dimorphism
2002
22q11.21 Deletion Syndromes: A Review of Proximal, Central, and Distal Deletions and Their Associated Features
2015 Standout
Prefrontal neurons and the genetics of schizophrenia
2001
Kinetics and Crystal Structure of Catechol-O-Methyltransferase Complex with Co-Substrate and a Novel Inhibitor with Potential Therapeutic Application
2002
Catechol- O -methyltransferase inhibition increases pain sensitivity through activation of both β2- and β3-adrenergic receptors
2006
Aggressive behavior in schizophrenia is associated with the low enzyme activity COMT polymorphism: A replication study
2003
REPuter: the manifold applications of repeat analysis on a genomic scale
2001 Standout
Biological Effects of COMT Haplotypes and Psychosis Risk in 22q11.2 Deletion Syndrome
2013
Quantitative role of COMT in dopamine clearance in the prefrontal cortex of freely moving mice
2010
Genetic Determinants of Time Perception Mediated by the Serotonergic System
2010
Dopamine system genes associated with parenting in the context of daily hassles
2007
CYP2C9 Genotype-guided Warfarin Prescribing Enhances the Efficacy and Safety of Anticoagulation: A Prospective Randomized Controlled Study
2007
Genetics of human prefrontal function
2003
The Physiology, Signaling, and Pharmacology of Dopamine Receptors
2011 Standout
Pathophysiological distortions in time perception and timed performance
2011 Standout
Stress signalling pathways that impair prefrontal cortex structure and function
2009 Standout
Moderation of the Effect of Adolescent-Onset Cannabis Use on Adult Psychosis by a Functional Polymorphism in the Catechol-O-Methyltransferase Gene: Longitudinal Evidence of a Gene X Environment Interaction
2005
Linkage study of Catechol-O-Methyltransferase and attention-deficit hyperactivity disorder
1999
Higher scores of self reported schizotypy in healthy young males carrying the COMT high activity allele
2002
Polyphenols: food sources and bioavailability
2004 Standout
Beyond diathesis stress: Differential susceptibility to environmental influences.
2009 Standout
Hubris syndrome: An acquired personality disorder? A study of US Presidents and UK Prime Ministers over the last 100 years
2009 Standout
Impulsivity as a vulnerability marker for substance-use disorders: Review of findings from high-risk research, problem gamblers and genetic association studies
2008 Standout
Persistent postsurgical pain: risk factors and prevention
2006 Standout
A structure-activity relationship study of catechol-O-methyltransferase inhibitors combining molecular docking and 3D QSAR methods
2003
Association of catechol-O-methyltransferase genetic variants with outcome in patients undergoing surgical treatment for lumbar degenerative disc disease
2010
Association study of NlaIII and MspI genetic polymorphisms of catechol-O-methyltransferase gene and susceptibility to Schizophrenia
1997
Schizophrenia genes, gene expression, and neuropathology: on the matter of their convergence
2004 Standout
Candidate gene studies of ADHD: a meta-analytic review
2009
Membrane electrostatics
1990
Purification methods of mammalian catechol-O-methyltransferases
1996
The molecular genetics of schizophrenia: new findings promise new insights
2003
No association between low- and high-activity catecholamine-methyl-transferase (COMT) and attention deficit hyperactivity disorder (ADHD) in a sample of Turkish children
2000
A Haplotype Implicated in Schizophrenia Susceptibility Is Associated with Reduced COMT Expression in Human Brain
2003
Variants in the catechol-o-methyltransferase (COMT) gene are associated with schizophrenia in Irish high-density families
2004
Conformational preferences and basicities of monofluorinated cyclopropyl amines in comparison to cyclopropylamine and 2-fluoroethylamine
2008
Chronic Back Pain Is Associated with Decreased Prefrontal and Thalamic Gray Matter Density
2004 Standout
The BDNF val66met Polymorphism Affects Activity-Dependent Secretion of BDNF and Human Memory and Hippocampal Function
2003 Standout
Cannabis use and risk of psychotic or affective mental health outcomes: a systematic review
2007 Standout
The biopsychosocial approach to chronic pain: Scientific advances and future directions.
2007 Standout
Association of Ala72Ser polymorphism with COMT enzyme activity and the risk of schizophrenia in Koreans
2005
The Endophenotype Concept in Psychiatry: Etymology and Strategic Intentions
2003 Standout
Association study of a functional catechol-O-methyltransferase gene polymorphism in Japanese schizophrenics
1998
Plasma Metanephrines Are Markers of Pheochromocytoma Produced by Catechol-O-Methyltransferase Within Tumors
1998
Expression and Intracellular Localization of Catechol O‐methyltransferase in Transfected Mammalian Cells
1997
Epistatic and Functional Interactions of Catechol-O-Methyltransferase (COMT) and AKT1 on Neuregulin1-ErbB Signaling in Cell Models
2010
No association between catechol-O-methyltransferase (COMT) gene polymorphism and attention deficit hyperactivity disorder (ADHD) in an Irish sample
2000
Non-specific low back pain
2011 Standout
Catechol O-Methyltransferase (COMT) mRNA Expression in the Dorsolateral Prefrontal Cortex of Patients with Schizophrenia
2003
Family-based linkage disequilibrium mapping using SNP marker haplotypes: application to a potential locus for schizophrenia at chromosome 22q11
2000
The effects of gender and catechol O-methyltransferase (COMT) Val108/158Met polymorphism on emotion regulation in velo-cardio-facial syndrome (22q11.2 deletion syndrome): An fMRI study
2010
Association Between a Functional Catechol O-Methyltransferase Gene Polymorphism and Schizophrenia: Meta-Analysis of Case-Control and Family-Based Studies
2003
Lack of association of functional cathechol-O-methyltransferase gene polymorphism in schizophrenia
1997
Catechol-o-Methyltransferase, Cognition, and Psychosis: Val158Met and Beyond
2006
The Attention System of the Human Brain: 20 Years After
2012 Standout
A catechol- O -methyltransferase that is essential for auditory function in mice and humans
2008 StandoutNobel
Confirmation of an excess of the high enzyme activity COMTval allele in heroin addicts in a family-based haplotype relative risk study
2000
Role of Dopamine in the Motivational and Cognitive Control of Behavior
2008
Haplotype relative risk study of catechol-O-methyltransferase (COMT) and attention deficit hyperactivity disorder (ADHD): Association of the high-enzyme activity val allele with adhd impulsive-hyperactive phenotype
1999
Nitrile-Containing Pharmaceuticals: Efficacious Roles of the Nitrile Pharmacophore
2010 Standout
Implicit Solvation Models: Equilibria, Structure, Spectra, and Dynamics
1999 Standout
Cortical inhibitory neurons and schizophrenia
2005 Standout
A New 2,2,2-Trifluoroethanol Model for Molecular Dynamics Simulations
2000
High-activity catechol-O-methyltransferase allele is more prevalent in polysubstance abusers
1997
Transport phenomena in nanofluidics
2008 Standout
AnFgf8mouse mutant phenocopies human 22q11 deletion syndrome
2002 StandoutNobel
Executive Functions
2012 Standout
Catechol-O-methyltransferase (COMT): Biochemistry, Molecular Biology, Pharmacology, and Clinical Efficacy of the New Selective COMT Inhibitors
1999
Force measurements with the atomic force microscope: Technique, interpretation and applications
2005 Standout
Linkage disequilibrium on theCOMT gene in French schizophrenics and controls
1999
QM−FE and Molecular Dynamics Calculations on Catechol O-Methyltransferase: Free Energy of Activation in the Enzyme and in Aqueous Solution and Regioselectivity of the Enzyme-Catalyzed Reaction
2000
Conditional Deletion of Focal Adhesion Kinase Leads to Defects in Ventricular Septation and Outflow Tract Alignment
2007 StandoutNobel
Temporomandibular Disorders
2008 Standout
Electrostatic Basis for Enzyme Catalysis
2006 StandoutNobel
No evidence for allelic association between schizophrenia and a polymorphism determining high or low catechol O-methyltransferase activity
1996
Ab Initio Evaluation of the Free Energy Surfaces for the General Base/Acid Catalyzed Thiolysis of Formamide and the Hydrolysis of Methyl Thiolformate: A Reference Solution Reaction for Studies of Cysteine Proteases
2001 StandoutNobel
Rapid metabolic evolution in human prefrontal cortex
2011 StandoutNobel
Effect of COMT Val 108/158 Met genotype on frontal lobe function and risk for schizophrenia
2001 Standout
A Theoretical Examination of the Factors Controlling the Catalytic Efficiency of a Transmethylation Enzyme: Catechol O-Methyltransferase
1997
Microglial M1/M2 polarization and metabolic states
2015 Standout
How important are entropic contributions to enzyme catalysis?
2000 StandoutNobel
Coupled-cluster methods with noniterative triple excitations for restricted open-shell Hartree–Fock and other general single determinant reference functions. Energies and analytical gradients
1993 Standout
Catalytic Asymmetric Protonation of Silyl Ketene Imines
2013 StandoutNobel
COMT val 158 met Genotype Affects µ-Opioid Neurotransmitter Responses to a Pain Stressor
2003 Science
The Concise Guide toPHARMACOLOGY 2013/14: Enzymes
2013
Synopsis of Some Recent Tactical Application of Bioisosteres in Drug Design
2011 Standout
Analytic gradients for coupled-cluster energies that include noniterative connected triple excitations: Application to c i s- and t r a n s-HONO
1991
Pheochromocytoma and Paraganglioma: An Endocrine Society Clinical Practice Guideline
2014 Standout
Molecular Genetics of Attention-Deficit/Hyperactivity Disorder
2005 Standout
Works of Timo Lotta being referenced
Kinetics of Human Soluble and Membrane-Bound Catechol O-Methyltransferase: A Revised Mechanism and Description of the Thermolabile Variant of the Enzyme
1995
Metabolism of OR-1896, a metabolite of levosimendan, in rats and humans
2008
Iron(III)-Chelating Properties of the Novel Catechol O-Methyltransferase Inhibitor Entacapone in Aqueous Solution
1997
PLS modelling of structure?activity relationships of catechol O-methyltransferase inhibitors
1992
Fourier transform infrared study of fully hydrated dimyristoylphosphatidylglycerol. Effects of sodium on the sn-1' and sn-3' headgroup stereoisomers
1988
Identification of major metabolites of the catechol-O-methyltransferase-inhibitor nitecapone in human urine.
1991
Thermal and IR-induced conformer interconversion processes for 2-fluoroethylamine in several low-temperature matrix media and ab initio 4-31G, 4-31G(N*), and 6-31G** calculations
1985
Ab initio calculations on ethanol and 2-substituted fluorine and chlorine containing mono-, di- and tri-haloethanols, with reference to conformer interconversions at low temperatures
1984
Ab initio calculations on hono: Energies, geometries and force fields on different levels of theory
1985