Citation Impact
Citing Papers
Histone demethylase KDM6A directly senses oxygen to control chromatin and cell fate
2019 StandoutScienceNobel
Chromatin modifiers and the promise of epigenetic therapy in acute leukemia
2014
Structure-Based Virtual Screening for Drug Discovery: a Problem-Centric Review
2012
TAILS N-terminomics and proteomics reveal complex regulation of proteolytic cleavage by O-glycosylation
2018
Bump-and-Hole Engineering Identifies Specific Substrates of Glycosyltransferases in Living Cells
2020 StandoutNobel
dCas9 fusion to computer-designed PRC2 inhibitor reveals functional TATA box in distal promoter region
2022 StandoutNobel
The molecular hallmarks of epigenetic control
2016 Standout
The RNA Binding Protein Quaking Regulates Formation of circRNAs
2015 Standout
Role of reactive oxygen species in antibiotic action and resistance
2009
Antibacterial activity of curcumin via apoptosis-like response in Escherichia coli
2016
Histone lysine demethylases as targets for anticancer therapy
2013
Epigenetic impact of dietary polyphenols in cancer chemoprevention: Lifelong remodeling of our epigenomes
2012
Dual-action inhibitors of HIF prolyl hydroxylases that induce binding of a second iron ion
2012 StandoutNobel
Regulation of chromatin by histone modifications
2011 Standout
Building the Connectivity Map of epigenetics: Chromatin profiling by quantitative targeted mass spectrometry
2014
The Role of the Histone Methyltransferase Enhancer of Zeste Homolog 2 (EZH2) in the Pathobiological Mechanisms Underlying Inflammatory Bowel Disease (IBD)
2016
Hallmarks of aging: An expanding universe
2023 Standout
Applications of CRISPR-Cas Enzymes in Cancer Therapeutics and Detection
2018 StandoutNobel
From inflammaging to healthy aging by dietary lifestyle choices: is epigenetics the key to personalized nutrition?
2015
Microbial Persistence and the Road to Drug Resistance
2013
Injury Induces Endogenous Reprogramming and Dedifferentiation of Neuronal Progenitors to Multipotency
2017
Cancer Epigenetics: From Mechanism to Therapy
2012 Standout
Antimicrobials as promoters of genetic variation
2012
A Structural Perspective on Readout of Epigenetic Histone and DNA Methylation Marks
2016
Cryptic binding sites on proteins: definition, detection, and druggability
2018
Unravelling the genomic targets of small molecules using high-throughput sequencing
2014
The threat of antimicrobial resistance in developing countries: causes and control strategies
2017 Standout
Evidence for Induction of Integron-Based Antibiotic Resistance by the SOS Response in a Clinical Setting
2012
A chemical probe toolbox for dissecting the cancer epigenome
2017
Environmental factors influencing the development and spread of antibiotic resistance
2017 Standout
[2+2] Photocycloaddition of Cinnamates in Flow and Development of a Thiourea Catalyst
2015
Epigenetic protein families: a new frontier for drug discovery
2012
Hypoxia-inducible factors promote breast cancer stem cell specification and maintenance in response to hypoxia or cytotoxic chemotherapy
2018 StandoutNobel
PROTAC targeted protein degraders: the past is prologue
2022 Standout
Driver mutations of cancer epigenomes
2014
Histone Modifications and Cancer
2016
The FDA-approved drug ivermectin inhibits the replication of SARS-CoV-2 in vitro
2020 Standout
Development of homogeneous luminescence assays for histone demethylase catalysis and binding
2010
Modulation of EZH2 expression in T cells improves efficacy of anti–CTLA-4 therapy
2018 StandoutNobel
A Brief History of the Antibiotic Era: Lessons Learned and Challenges for the Future
2010 Standout
Ivermectin: panacea for resource-poor communities?
2014 StandoutNobel
Tackling antibiotic resistance: the environmental framework
2015 Standout
Antibiotic Resistance Acquired through a DNA Damage-Inducible Response in Acinetobacter baumannii
2013
The role of senescent cells in ageing
2014 StandoutNature
Antitumor effects of pharmacological EZH2 inhibition on malignant peripheral nerve sheath tumor through the miR-30a and KPNB1 pathway
2015
Cystine transporter SLC7A11/xCT in cancer: ferroptosis, nutrient dependency, and cancer therapy
2020 Standout
Oxidative Stress: Harms and Benefits for Human Health
2017 Standout
Progress in the Discovery of Small-Molecule Inhibitors of Bromodomain–Histone Interactions
2011
How antibiotics kill bacteria: from targets to networks
2010 Standout
Starvation, Together with the SOS Response, Mediates High Biofilm-Specific Tolerance to the Fluoroquinolone Ofloxacin
2013
The history and future of targeting cyclin-dependent kinases in cancer therapy
2015 Standout
HIF activation causes synthetic lethality between the VHL tumor suppressor and the EZH1 histone methyltransferase
2017 StandoutNobel
Antibacterial activity and mechanism of cinnamon essential oil against Escherichia coli and Staphylococcus aureus
2015 Standout
Mapping the Efficiency and Physicochemical Trajectories of Successful Optimizations
2018
Mammalian SWI/SNF chromatin remodeling complexes and cancer: Mechanistic insights gained from human genomics
2015
Betti reaction enables efficient synthesis of 8-hydroxyquinoline inhibitors of 2-oxoglutarate oxygenases
2015 StandoutNobel
The Hitchhiker’s Guide to Flow Chemistry
2017 Standout
Inactivation of the PBRM1 tumor suppressor gene amplifies the HIF-response in VHL −/− clear cell renal carcinoma
2017 StandoutNobel
Antibiotics and Bacterial Resistance in the 21st Century
2014 Standout
Molecular Pathways: SWI/SNF (BAF) Complexes Are Frequently Mutated in Cancer—Mechanisms and Potential Therapeutic Insights
2013
Selective Small Molecule Probes for the Hypoxia Inducible Factor (HIF) Prolyl Hydroxylases
2013 StandoutNobel
Structure and function of histone methylation binding proteinsThis paper is one of a selection of papers published in this Special Issue, entitled CSBMCB’s 51st Annual Meeting – Epigenetics and Chromatin Dynamics, and has undergone the Journal’s usual peer review process.
2009
Protein Ensemble Generation Through Variational Autoencoder Latent Space Sampling
2024 StandoutNobel
DNA methylation in the central and efferent limbs of the chemoreflex requires carotid body neural activity
2017 StandoutNobel
Dietary and Policy Priorities for Cardiovascular Disease, Diabetes, and Obesity
2016 Standout
Structural Simplification of Bioactive Natural Products with Multicomponent Synthesis. 3. Fused Uracil-Containing Heterocycles as Novel Topoisomerase-Targeting Agents
2011
Cyclic di-GMP: the First 25 Years of a Universal Bacterial Second Messenger
2013 Standout
Combination therapy in combating cancer
2017 Standout
Turmeric (Curcuma longa) and its major constituent (curcumin) as nontoxic and safe substances: Review
2018 Standout
Biofilm-Related Infections: Bridging the Gap between Clinical Management and Fundamental Aspects of Recalcitrance toward Antibiotics
2014 Standout
The Versatile Role of microRNA-30a in Human Cancer
2017 Standout
Molecular Docking: Challenges, Advances and its Use in Drug Discovery Perspective
2018 Standout
Histone demethylase JMJD2C: epigenetic regulators in tumors
2017
Exposure to sub-inhibitory concentrations of gentamicin, ciprofloxacin and cefotaxime induces multidrug resistance and reactive oxygen species generation in meticillin-sensitive Staphylococcus aureus
2017 StandoutNobel
Paradigm Shift in Discovering Next-Generation Anti-Infective Agents: Targeting Quorum Sensing, C-Di-Gmp Signaling and Biofilm Formation in Bacteria with Small Molecules
2010
Ivermectin is a specific inhibitor of importin α/β-mediated nuclear import able to inhibit replication of HIV-1 and dengue virus
2012
Ecology and Evolution as Targets: the Need for Novel Eco-Evo Drugs and Strategies To Fight Antibiotic Resistance
2011
Antimicrobial Resistance in ESKAPE Pathogens
2020 Standout
Metal-Free Multicomponent Syntheses of Pyridines
2014 Standout
The Molecular Balancing Act of p16INK4a in Cancer and Aging
2013
Works of Tim J. Wigle being referenced
Inhibitors of RecA Activity Discovered by High-Throughput Screening: Cell-Permeable Small Molecules Attenuate the SOS Response in Escherichia coli
2009
Drugging the human methylome: an emerging modality for reversible control of aberrant gene transcription
2013
Accessing Protein Methyltransferase and Demethylase Enzymology Using Microfluidic Capillary Electrophoresis
2010
A High-Throughput Mass Spectrometry Assay Coupled with Redox Activity Testing Reduces Artifacts and False Positives in Lysine Demethylase Screening
2015
The Y641C mutation of EZH2 alters substrate specificity for histone H3 lysine 27 methylation states
2011
A687V EZH2 is a gain‐of‐function mutation found in lymphoma patients
2012
Directed molecular screening for RecA ATPase inhibitors
2007
Epigenetics: tools and technologies
2010
Screening for Inhibitors of Low-Affinity Epigenetic Peptide-Protein Interactions: An AlphaScreen™-Based Assay for Antagonists of Methyl-Lysine Binding Proteins
2009
Conformational Adaptation Drives Potent, Selective and Durable Inhibition of the Human Protein Methyltransferase DOT1L
2012
Novel Inhibitors of E. coli RecA ATPase Activity
2010
Small-Molecule Ligands of Methyl-Lysine Binding Proteins
2011
Durable tumor regression in genetically altered malignant rhabdoid tumors by inhibition of methyltransferase EZH2
2013
Aryl Pyrazoles as Potent Inhibitors of Arginine Methyltransferases: Identification of the First PRMT6 Tool Compound
2015
EPZ011989, A Potent, Orally-Available EZH2 Inhibitor with Robust in Vivo Activity
2015
Identification of Non-Peptide Malignant Brain Tumor (MBT) Repeat Antagonists by Virtual Screening of Commercially Available Compounds
2010
The Importance of Being Me: Magic Methyls, Methyltransferase Inhibitors, and the Discovery of Tazemetostat
2016