Tim Holbrook

Virus-Induced Autoimmunity

The american rheumatism association 1987 revised criteria for the classification of rheumatoid arthritis

Antinuclear Antibodies: Diagnostic Markers for Autoimmune Diseases and Probes for Cell Biology

Small-Vessel Vasculitis

Regulatory T Cells

Structure and physical map of 64 variable segments in the 3′ 0.8–megabase region of the human immunoglobulin heavy–chain locus

Extent of γδ T cell involvement in the pneumonia caused by sendai virus

Control of Autoimmunity by Naturally Arising Regulatory CD4+ T Cells

HAPPY mapping of a YAC reveals alternative haplotypes in the human immunoglobulin V_Hlocus

Rheumatoid Arthritis

Tolerance, Danger, and the Extended Family

Myasthenia Gravis

Physical map of the 3′ region of the human immunoglobulin heavy chain locus: clustering of autoantibody-related variable segments in one haplotype.

Involvement of receptor activator of NFκB ligand and tumor necrosis factor-α in bone destruction in rheumatoid arthritis

Cryoglobulinemic glomerulonephritis: A membranoproliferative glomerulonephritis induced by hepatitis C virus

Germline variable region gene segment derivation of human monoclonal anti-Rh(D) antibodies. Evidence for affinity maturation by somatic hypermutation and repertoire shift.

Virus-induced autoantibody response to a transgenic viral antigen

Thioredoxin as a biomarker for oxidative stress in patients with rheumatoid arthritis

Atherosclerosis — An Inflammatory Disease

The complete nucleotide sequences of the heavy chain variable regions of six monospecific rheumatoid factors derived from Epstein-Barr virus-transformed B cells isolated from the synovial tissue of patients with rheumatoid arthritis. Further evidence that some autoantibodies are unmutated copies of germ line genes.

The repertoire of human germline vH sequences reveals about fifty groups of VH segments with different hypervariable loops

Structural repertoire of the human VH segments

Platelet Activation and Binding of Complement Components to Platelets Induced by Immune Complexes

A Pilot Study of Idiotypic Vaccination for Follicular B-cell Lymphoma Using a Genetic Approach. University of Bristol, Bristol, United Kingdom

Cyclin/PCNA is the auxiliary protein of DNA polymerase-δ

Different Functional Domains of the Adenovirus E1A Gene are Involved in Regulation of Host Cell Cycle Products

Immunological Surveillance of Tumors in the Context of Major Histocompatibility Complex Restriction of T Cell Function

NaturallyArisingCD4⁺RegulatoryT Cells forImmunologicSelf-Tolerance andNegativeControl ofImmuneResponses

Seronegative Rheumatoid Arthritis

Thymus and autoimmunity: capacity of the normal thymus to produce pathogenic self-reactive T cells and conditions required for their induction of autoimmune disease.

Lamin B autoantibodies in sera of certain patients with systemic lupus erythematosus.

Analysis of Autoimmunity through Experimental Models of Thyroiditis and Allergic Encephalomyelitis

Lack of connectivity between the induced and autoimmune repertoires of lpr/lpr mice.

Small nuclear ribonucleoprotein particle assembly in vivo: Demonstration of a 6S RNA-free core precursor and posttranslational modification

Autoantibodies to Nuclear Antigens (ANA): Their Immunobiology and Medicine

Different functional domains of the adenovirus E1A gene are involved in regulation of host cell cycle products.

The Human Immune Response Region (HLA‐D) and Disease Susceptibility

Study on cellular events in post-thymectomy autoimmune oophoritis in mice. II. Requirement of Lyt-1 cells in normal female mice for the prevention of oophoritis.

Nocardia species: host-parasite relationships

Human autoantibodies reactive with the signal-recognition particle.

Dysbiosis Contributes to Arthritis Development via Activation of Autoreactive T Cells in the Intestine

The Biology and Detection of Immune Complexes

Pulse labeling of small nuclear ribonucleoproteins in vivo reveals distinct patterns of antigen recognition by human autoimmune antibodies.

Thymus and Autoimmunity: Production of CD25+CD4+ Naturally Anergic and Suppressive T Cells as a Key Function of the Thymus in Maintaining Immunologic Self-Tolerance

Somatic Hypermutations Confer Rheumatoid Factor Activity in Hepatitis C Virus–Associated Mixed Cryoglobulinemia

Autoantibodies in infectious mononucleosis have specificity for the glycine-alanine repeating region of the Epstein-Barr virus nuclear antigen.

B-lymphocyte activation with an extract of Nocardia brasiliensis

Sharing of Antigenic Determinants between the Nicotinic Acetylcholine Receptor and Proteins inEscherichia coli, Proteus vulgaris,andKlebsiella pneumoniae

Virus and Autoimmunity: Induction of Autoimmune Disease in Mice by Mouse T Lymphotropic Virus (MTLV) Destroying CD4+ T Cells

Antibodies in human serum that precipitate ribonuclease P.

In vitro effects of Epstein-Barr virus on peripheral blood mononuclear cells from patients with rheumatoid arthritis and normal subjects.

Age-associated changes in Epstein-Barr virus-induced human lymphocyte autoantibody responses.