Standout Papers
Citation Impact
Citing Papers
Suppression of Aging in Mice by the Hormone Klotho
2005 StandoutScience
In vivo imaging of hydrogen peroxide production in a murine tumor model with a chemoselective bioluminescent reporter
2010 StandoutNobel
Tet Proteins Can Convert 5-Methylcytosine to 5-Formylcytosine and 5-Carboxylcytosine
2011 StandoutScience
Strategy for Dual-Analyte Luciferin Imaging: In Vivo Bioluminescence Detection of Hydrogen Peroxide and Caspase Activity in a Murine Model of Acute Inflammation
2013 StandoutNobel
Loss of cryptochrome reduces cancer risk in p53 mutant mice
2009 StandoutNobel
Caloric Restriction Delays Disease Onset and Mortality in Rhesus Monkeys
2009 StandoutScience
The Critical Role of Metabolic Pathways in Aging
2012
Whole-genome resequencing reveals loci under selection during chicken domestication
2010 StandoutNature
Hallmarks of Cancer: The Next Generation
2011 Standout
Early aging and age-related pathologies in mice deficient in BMAL1, the core componentof the circadian clock
2006
Base-excision repair of oxidative DNA damage
2007 StandoutNature
Demethylation of 3-Methylthymine in DNA by Bacterial and Human DNA Dioxygenases
2004 StandoutNobel
Short-Term Effects of Nose-Only Cigarette Smoke Exposure on Glutathione Redox Homeostasis, Cytochrome P450 1A1/2 and Respiratory Enzyme Activities in Mice Tissues
2013 Standout
The role of DNA damage and repair in aging through the prism of Koch-like criteria
2012
Analysis of 8-oxo-7,8-dihydro-2′-deoxyguanosine by ultra high pressure liquid chromatography–heat assisted electrospray ionization–tandem mass spectrometry
2009
Mitochondria: Dynamic Organelles in Disease, Aging, and Development
2006 Standout
Oxidative stress, dysfunctional glucose metabolism and Alzheimer disease
2019 Standout
Neural mechanisms of ageing and cognitive decline
2010 Nature
HIF-1 mediates metabolic responses to intratumoral hypoxia and oncogenic mutations
2013 StandoutNobel
Adipocytes as regulators of energy balance and glucose homeostasis
2006 StandoutNature
Amyloid beta, mitochondrial dysfunction and synaptic damage: implications for cognitive decline in aging and Alzheimer's disease
2008
Sirt3 Mediates Reduction of Oxidative Damage and Prevention of Age-Related Hearing Loss under Caloric Restriction
2010
Oxygen sensing by HIF hydroxylases
2004 StandoutNobel
AlkB-mediated oxidative demethylation reverses DNA damage in Escherichia coli
2002 Nature
Does renal ageing affect survival?
2007
Axis of ageing: telomeres, p53 and mitochondria
2012
A stress response pathway regulates DNA damage through β2-adrenoreceptors and β-arrestin-1
2011 StandoutNatureNobel
Attenuation of Sarcopenia by Dietary Restriction in Rhesus Monkeys
2008
Mitochondria: In Sickness and in Health
2012 Standout
Minimal Methylated Substrate and Extended Substrate Range of Escherichia coli AlkB Protein, a 1-Methyladenine-DNA Dioxygenase
2003 StandoutNobel
Mitochondrial fragmentation in neurodegeneration
2008
Ultra-Deep Sequencing of Mouse Mitochondrial DNA: Mutational Patterns and Their Origins
2011
Histone demethylation by a family of JmjC domain-containing proteins
2005 StandoutNature
Piezo2 is the major transducer of mechanical forces for touch sensation in mice
2014 StandoutNatureNobel
Senescence-associated phenotypes in Akita diabetic mice are enhanced by absence of bradykinin B2 receptors
2006
NOD1 and NOD2 signalling links ER stress with inflammation
2016 StandoutNature
Metabolic Reprogramming in Dietary Restriction
2006
Accumulating Mitochondrial DNA Mutations Drive Premature Hematopoietic Aging Phenotypes Distinct from Physiological Stem Cell Aging
2011
Stems Cells and the Pathways to Aging and Cancer
2008
Mitochondrial Fusion Is Required for mtDNA Stability in Skeletal Muscle and Tolerance of mtDNA Mutations
2010
Alzheimer's Disease
2010 Standout
Resistance of quiescent and proliferating airway epithelial cells to H2O2challenge
2007
Mitochondrial dysfunction and oxidative stress in neurodegenerative diseases
2006 StandoutNature
Glypican-1 identifies cancer exosomes and detects early pancreatic cancer
2015 StandoutNature
The role of senescent cells in ageing
2014 StandoutNature
DNA deletions and clonal mutations drive premature aging in mitochondrial mutator mice
2008
The Hallmarks of Aging
2013 Standout
The Retinoblastoma Binding Protein RBP2 Is an H3K4 Demethylase
2007 StandoutNobel
Naturally occurring p16Ink4a-positive cells shorten healthy lifespan
2016 StandoutNature
Mitochondrial Rhomboid PARL Regulates Cytochrome c Release during Apoptosis via OPA1-Dependent Cristae Remodeling
2006
The Aging Stress Response
2010
Inflammation, metaflammation and immunometabolic disorders
2017 StandoutNature
Autophagy-related Protein 32 Acts as Autophagic Degron and Directly Initiates Mitophagy
2012 StandoutNobel
Peroxynitrite: biochemistry, pathophysiology and development of therapeutics
2007 Standout
Single-cell transcriptomic analysis of Alzheimer’s disease
2019 StandoutNature
DNA damage in telomeres and mitochondria during cellular senescence: is there a connection?
2007
Pathways towards and away from Alzheimer's disease
2004 StandoutNature
Mitochondrial DNA and ageing
2006
Soluble amyloid precursor protein (APP) regulates transthyretin and Klotho gene expression without rescuing the essential function of APP
2010 StandoutNobel
Targeting Mitochondrial Dysfunction: Role for PINK1 and Parkin in Mitochondrial Quality Control
2011
Proapoptotic BAX and BAK: A Requisite Gateway to Mitochondrial Dysfunction and Death
2001 StandoutScience
Accumulation of premutagenic DNA lesions in mice defective in removal of oxidative base damage
1999 StandoutNobel
The Aging Brain
2008
Ancient Ethiopian genome reveals extensive Eurasian admixture in Eastern Africa
2015 StandoutScience
Mutation of the mouse klotho gene leads to a syndrome resembling ageing.
1997 Standout
The p24 proteins are not essential for vesicular transport in Saccharomyces cerevisiae
2000 StandoutNobel
Quality Control by DNA Repair
1999 StandoutScienceNobel
Lysosomal activity regulatesCaenorhabditis elegansmitochondrial dynamics through vitamin B12 metabolism
2020 StandoutNobel
HAPLOFIND: A New Method for High-Throughput mtDNA Haplogroup Assignment
2013
Erythroid dysplasia, megaloblastic anemia, and impaired lymphopoiesis arising from mitochondrial dysfunction
2009
Signal transduction by reactive oxygen species
2011 Standout
Somatic Progenitor Cell Vulnerability to Mitochondrial DNA Mutagenesis Underlies Progeroid Phenotypes in Polg Mutator Mice
2012
The Caenorhabditis elegans ARIP-4 DNA helicase couples mitochondrial surveillance to immune, detoxification, and antiviral pathways
2022 StandoutNobel
Spermidine in health and disease
2018 StandoutScience
Mouse models of mitochondrial DNA defects and their relevance for human disease
2009
Reversal of DNA alkylation damage by two human dioxygenases
2002 StandoutNobel
Bradykinin B1 and B2 receptors both have protective roles in renal ischemia/reperfusion injury
2007 StandoutNobel
Mitochondrial DNA mutations in disease and aging
2011
Molecular Mechanisms of Mammalian DNA Repair and the DNA Damage Checkpoints
2004 StandoutNobel
Works of Tim Hofer being referenced
Mitochondrial DNA mutations, energy metabolism and apoptosis in aging muscle
2006
The transcriptosomal response of human A549 lung cells to a hydrogen peroxide-generating system: relationship to DNA damage, cell cycle arrest, and caspase activation
2004
Mitochondrial DNA Mutations Induce Mitochondrial Dysfunction, Apoptosis and Sarcopenia in Skeletal Muscle of Mitochondrial DNA Mutator Mice
2010
RNA oxidation in Alzheimer disease and related neurodegenerative disorders
2009
A method to determine RNA and DNA oxidation simultaneously by HPLC-ECD: greater RNA than DNA oxidation in rat liver after doxorubicin administration
2006
Hepatic Oxidative Stress During Aging: Effects of 8% Long-Term Calorie Restriction and Lifelong Exercise
2006
Reduction of Oxidation during the Preparation of DNA and Analysis of 8-Hydroxy-2‘-deoxyguanosine
1998
Mitochondrial DNA Mutations, Oxidative Stress, and Apoptosis in Mammalian Aging
2005 StandoutScience