Citation Impact
Citing Papers
Complement and microglia mediate early synapse loss in Alzheimer mouse models
2016 StandoutScience
Global analysis of protein folding using massively parallel design, synthesis, and testing
2017 StandoutScienceNobel
Protein Misfolding, Amyloid Formation, and Human Disease: A Summary of Progress Over the Last Decade
2017 Standout
α-Synuclein in Central Nervous System and from Erythrocytes, Mammalian Cells, and Escherichia coli Exists Predominantly as Disordered Monomer
2012
Apolipoprotein E and Alzheimer's disease: the influence of apolipoprotein E on amyloid-β and other amyloidogenic proteins
2017
Functional and dynamic polymerization of the ALS-linked protein TDP-43 antagonizes its pathologic aggregation
2017
Small Heat-shock Proteins Prevent α-Synuclein Aggregation via Transient Interactions and Their Efficacy Is Affected by the Rate of Aggregation
2016
The role of liquid–liquid phase separation in aggregation of the TDP-43 low-complexity domain
2019 Standout
A pupal transcriptomic screen identifies Ral as a target of store-operated calcium entry in Drosophila neurons
2017 StandoutNobel
Sorting out release, uptake and processing of alpha‐synuclein during prion‐like spread of pathology
2015
Limelight on Alpha-Synuclein: Pathological and Mechanistic Implications in Neurodegeneration
2013
Mechanisms, regulation and functions of the unfolded protein response
2020 Standout
Parkinson disease
2017 Standout
CHARMM All-Atom Additive Force Field for Sphingomyelin: Elucidation of Hydrogen Bonding and of Positive Curvature
2014
Pathological roles of α-synuclein in neurological disorders
2011
CD22 blockade restores homeostatic microglial phagocytosis in ageing brains
2019 StandoutNatureNobel
Cerebrospinal fluid biomarkers in Parkinson disease
2013
Oxidative Stress Hypothesis in Alzheimer's Disease
1997 Standout
The role of autophagy in neurodegenerative disease
2013 Standout
The glymphatic pathway in neurological disorders
2018 Standout
Structural Characteristics of α-Synuclein Oligomers
2016
Sphingolipids and their metabolism in physiology and disease
2017 Standout
The Roles of PINK1, Parkin, and Mitochondrial Fidelity in Parkinson’s Disease
2015 Standout
The Neurovascular Unit Coming of Age: A Journey through Neurovascular Coupling in Health and Disease
2017 Standout
Neutral Sphingomyelinase-2 Deficiency Ameliorates Alzheimer's Disease Pathology and Improves Cognition in the 5XFAD Mouse
2016
Hexagonal Substructure and Hydrogen Bonding in Liquid-Ordered Phases Containing Palmitoyl Sphingomyelin
2015
VPS35 in Dopamine Neurons Is Required for Endosome-to-Golgi Retrieval of Lamp2a, a Receptor of Chaperone-Mediated Autophagy That Is Critical for -Synuclein Degradation and Prevention of Pathogenesis of Parkinson's Disease
2015
Understanding Dopaminergic Cell Death Pathways in Parkinson Disease
2016
Oxidative stress and cellular pathologies in Parkinson’s disease
2017
Slowing of neurodegeneration in Parkinson's disease and Huntington's disease: future therapeutic perspectives
2014
TRAP1 rescues PINK1 loss-of-function phenotypes
2013
COVID-19: A promising cure for the global panic
2020 Standout
Mitochondrial defects and oxidative stress in Alzheimer disease and Parkinson disease
2012
Membrane Curvature Sensing by Amphipathic Helices
2011
Tau in physiology and pathology
2015 Standout
Mitochondria: In Sickness and in Health
2012 Standout
Immune attack: the role of inflammation in Alzheimer disease
2015 Standout
Alzheimer Disease: An Update on Pathobiology and Treatment Strategies
2019 Standout
Role of Detergents in Conformational Exchange of a G Protein-coupled Receptor
2012 StandoutNobel
Inhibition of Amyloid Formation
2012
Reactive oxygen species (ROS) as pleiotropic physiological signalling agents
2020 Standout
Parkinson's disease
2015 Standout
The Unfolded Protein Response: Detecting and Responding to Fluctuations in the Protein-Folding Capacity of the Endoplasmic Reticulum
2019
Gut microbiome alterations in Alzheimer’s disease
2017 Standout
Fast protein folding kinetics
2014
Evidence that small molecule enhancement of β-hexosaminidase activity corrects the behavioral phenotype in Dutch APPE693Q mice through reduction of ganglioside-bound Aβ
2014
Bioenergetic Origins of Complexity and Disease
2011
Autophagy in Human Health and Disease
2013 Standout
Converging environmental and genetic pathways in the pathogenesis of Parkinson's disease
2011
Intrinsically disordered proteins in cellular signalling and regulation
2014 Standout
Recent Advances in α-Synuclein Functions, Advanced Glycation, and Toxicity: Implications for Parkinson’s Disease
2012
Alzheimer's disease
2016 Standout
Parkinson's disease and α‐synuclein expression
2011
α-Synuclein Populates Both Elongated and Broken Helix States on Small Unilamellar Vesicles
2011
Structural Insights into Amyloid Oligomers of the Parkinson Disease-related Protein α-Synuclein
2014
The mystery of membrane organization: composition, regulation and roles of lipid rafts
2017 Standout
Non-motor features of Parkinson disease
2017 Standout
Alpha-synuclein-induced neurodegeneration is exacerbated in PINK1 knockout mice
2014
Design of amyloidogenic peptide traps
2024 StandoutNobel
Alpha-synuclein and Protein Degradation Systems: a Reciprocal Relationship
2012
Reactive Astrocytes: Production, Function, and Therapeutic Potential
2017 Standout
Mitochondria: The Next (Neurode)Generation
2011
Mutant A53T α-Synuclein Induces Neuronal Death by Increasing Mitochondrial Autophagy
2011
Systematic Mutagenesis of α-Synuclein Reveals Distinct Sequence Requirements for Physiological and Pathological Activities
2012 StandoutNobel
Physiological Roles of Mitochondrial Reactive Oxygen Species
2012 Standout
The PI3K Pathway in Human Disease
2017 Standout
Pathogenesis of synaptic degeneration in Alzheimer's disease and Lewy body disease
2014
Etiology and pathogenesis of Parkinson's disease
2011
Mitochondria and cancer
2012 Standout
The associations between Parkinson’s disease and cancer: the plot thickens
2015
Solution NMR of SNAREs, complexin and α-synuclein in association with membrane-mimetics
2018
A Unique Microglia Type Associated with Restricting Development of Alzheimer’s Disease
2017 Standout
O-GlcNAc modification of small heat shock proteins enhances their anti-amyloid chaperone activity
2021 StandoutNobel
Molecular and Biological Compatibility with Host Alpha-Synuclein Influences Fibril Pathogenicity
2016
The amyloid state and its association with protein misfolding diseases
2014 Standout
G2019S-LRRK2 Expression Augments -Synuclein Sequestration into Inclusions in Neurons
2016
The amyloid hypothesis of Alzheimer's disease at 25 years
2016 Standout
Redox Mechanisms in Neurodegeneration: From Disease Outcomes to Therapeutic Opportunities
2018
Mitochondrial Dysfunction in Genetic Animal Models of Parkinson's Disease
2011
Comprehensive Review on Alzheimer’s Disease: Causes and Treatment
2020 Standout
Lipids and Alzheimer’s Disease
2020
Autophagy, mitochondria and oxidative stress: cross-talk and redox signalling
2011 Standout
Native α-synuclein induces clustering of synaptic-vesicle mimics via binding to phospholipids and synaptobrevin-2/VAMP2
2013 StandoutNobel
α‐Synuclein: The Long Distance Runner
2013
A soluble α-synuclein construct forms a dynamic tetramer
2011
Physicochemical Properties of Cells and Their Effects on Intrinsically Disordered Proteins (IDPs)
2014
CHARMM-GUI Input Generator for NAMD, GROMACS, AMBER, OpenMM, and CHARMM/OpenMM Simulations Using the CHARMM36 Additive Force Field
2015 Standout
What Genetics Tells us About the Causes and Mechanisms of Parkinson's Disease
2011
Endoplasmic reticulum-associated SKN-1A/Nrf1 mediates a cytoplasmic unfolded protein response and promotes longevity
2019 StandoutNobel
Development of Multifunctional Molecules as Potential Therapeutic Candidates for Alzheimer’s Disease, Parkinson’s Disease, and Amyotrophic Lateral Sclerosis in the Last Decade
2018
ROS-based lethality of Caenorhabditis elegans mitochondrial electron transport mutants grown on Escherichia coli siderophore iron release mutants
2019 StandoutNobel
The Molecular Structure of the Liquid-Ordered Phase of Lipid Bilayers
2013
Microglia Function in the Central Nervous System During Health and Neurodegeneration
2017 Standout
Site-Specific Interaction between α-Synuclein and Membranes Probed by NMR-Observed Methionine Oxidation Rates
2013
The Chemistry of Reactive Oxygen Species (ROS) Revisited: Outlining Their Role in Biological Macromolecules (DNA, Lipids and Proteins) and Induced Pathologies
2021 Standout
How neuroinflammation contributes to neurodegeneration
2016 StandoutScience
Mechanism of Oxidative Stress in Neurodegeneration
2012
Interaction of toxic and non-toxic HypF-N oligomers with lipid bilayers investigated at high resolution with atomic force microscopy
2016
The Synaptic Function of α-Synuclein
2015
Mitochondrial Contribution to Parkinson's Disease Pathogenesis
2011
Another Piece of the Membrane Puzzle: Extending Slipids Further
2012
Cryo-EM structure of alpha-synuclein fibrils
2018
Cell Biology of the Mitochondrion
2017
Reactive Oxygen Species (ROS)-Based Nanomedicine
2019 Standout
Impact of N-Terminal Acetylation of α-Synuclein on Its Random Coil and Lipid Binding Properties
2012
Solution conditions determine the relative importance of nucleation and growth processes in α-synuclein aggregation
2014
Seeking a Mechanism for the Toxicity of Oligomeric α-Synuclein
2015
Oxidative Stress: A Key Modulator in Neurodegenerative Diseases
2019 Standout
Membrane Morphology Is Actively Transformed by Covalent Binding of the Protein Atg8 to PE-Lipids
2014 StandoutNobel
Test of the 'glymphatic' hypothesis demonstrates diffusive and aquaporin-4-independent solute transport in rodent brain parenchyma
2017
α‐Synuclein oligomers and clinical implications for Parkinson disease
2012
Works of Tim Bartels being referenced
In Vivo Cross-linking Reveals Principally Oligomeric Forms of α-Synuclein and β-Synuclein in Neurons and Non-neural Cells
2013
Soluble, Prefibrillar α-Synuclein Oligomers Promote Complex I-dependent, Ca2+-induced Mitochondrial Dysfunction
2014
α-Synuclein occurs physiologically as a helically folded tetramer that resists aggregation
2011 Nature
New insights into cellular α-synuclein homeostasis in health and disease
2015
Parkinson-causing α-synuclein missense mutations shift native tetramers to monomers as a mechanism for disease initiation
2015
N-Alpha-Acetylation of α-Synuclein Increases Its Helical Folding Propensity, GM1 Binding Specificity and Resistance to Aggregation
2014
Soluble Aβ Oligomers Are Rapidly Sequestered from Brain ISF In Vivo and Bind GM1 Ganglioside on Cellular Membranes
2014
The N-Terminus of the Intrinsically Disordered Protein α-Synuclein Triggers Membrane Binding and Helix Folding
2010
Inhibition of mitochondrial fusion by α‐synuclein is rescued by PINK1, Parkin and DJ‐1
2010
Non-denaturing purification of alpha-Synuclein from erythrocytes
2011
KTKEGV repeat motifs are key mediators of normal α-synuclein tetramerization: Their mutation causes excess monomers and neurotoxicity
2015
Loss of native α-synuclein multimerization by strategically mutating its amphipathic helix causes abnormal vesicle interactions in neuronal cells
2017
Purification of α-Synuclein from Human Brain Reveals an Instability of Endogenous Multimers as the Protein Approaches Purity
2014
Raftlike Mixtures of Sphingomyelin and Cholesterol Investigated by Solid-State 2H NMR Spectroscopy
2008