Citation Impact
Citing Papers
Quantitative analysis of Argonaute protein reveals microRNA-dependent localization to stress granules
2006
P-Body Formation Is a Consequence, Not the Cause, of RNA-Mediated Gene Silencing
2007
Protein characterization of Saccharomyces cerevisiae RNA polymerase II after in vivo cross-linking
2007 StandoutNobel
The Dynamics of Mammalian P Body Transport, Assembly, and Disassembly In Vivo
2008
Emergence of the universal genetic code imprinted in an RNA record
2006
A Neuroligin-3 Mutation Implicated in Autism Increases Inhibitory Synaptic Transmission in Mice
2007 StandoutScienceNobel
A drug-controllable tag for visualizing newly synthesized proteins in cells and whole animals
2008 StandoutNobel
Inhibition of Translational Initiation by Let-7 MicroRNA in Human Cells
2005 Science
Structural inference of native and partially folded RNA by high-throughput contact mapping
2008 StandoutNobel
Movement of Eukaryotic mRNAs Between Polysomes and Cytoplasmic Processing Bodies
2005 Science
A subset of human 35S U5 proteins, including Prp19, function prior to catalytic step 1 of splicing
2004
A new function for the fragile X mental retardation protein in regulation of PSD-95 mRNA stability
2007
The FXG: A Presynaptic Fragile X Granule Expressed in a Subset of Developing Brain Circuits
2009
Structure and function of an RNase H domain at the heart of the spliceosome
2008
A Mouse Model of the Human Fragile X Syndrome I304N Mutation
2009
Staufen- and FMRP-Containing Neuronal RNPs Are Structurally and Functionally Related to Somatic P Bodies
2006
Fragile X Syndrome: Loss of Local mRNA Regulation Alters Synaptic Development and Function
2008
RAP55, a Cytoplasmic mRNP Component, Represses Translation in Xenopus Oocytes
2006
Mechanical Devices of the Spliceosome: Motors, Clocks, Springs, and Things
1998
Transcriptomic profiling of microglia and astrocytes throughout aging
2020
Phosphorylation of human PRP28 by SRPK2 is required for integration of the U4/U6-U5 tri-snRNP into the spliceosome
2008
Let Me Count the Ways: Mechanisms of Gene Regulation by miRNAs and siRNAs
2008
CD22 blockade restores homeostatic microglial phagocytosis in ageing brains
2019 StandoutNatureNobel
Human ADAR1 Prevents Endogenous RNA from Triggering Translational Shutdown
2018 StandoutNobel
A Common Core RNP Structure Shared between the Small Nucleoar Box C/D RNPs and the Spliceosomal U4 snRNP
2000 StandoutNobel
Mammalian Stress Granules and Processing Bodies
2007
PSF and p54nrb/NonO – multi‐functional nuclear proteins
2002
CGH-1 and the control of maternal mRNAs
2008
The Nuclear-Retained Noncoding RNA MALAT1 Regulates Alternative Splicing by Modulating SR Splicing Factor Phosphorylation
2010 Standout
The Spliceosome: Design Principles of a Dynamic RNP Machine
2009 Standout
Identification of small RNA pathway genes using patterns of phylogenetic conservation and divergence
2012 StandoutNatureNobel
nhl-2 Modulates MicroRNA Activity in Caenorhabditis elegans
2009 StandoutNobel
Ubiquitin binding by a variant Jab1/MPN domain in the essential pre-mRNA splicing factor Prp8p
2006
P Bodies and the Control of mRNA Translation and Degradation
2007
Making synaptic plasticity and memory last: mechanisms of translational regulation
2009
mRNA stability in eukaryotes
2000
Human Retroviral Host Restriction Factors APOBEC3G and APOBEC3F Localize to mRNA Processing Bodies
2006
General Translational Repression by Activators of mRNA Decapping
2005
Inactivation of Conserved C. elegans Genes Engages Pathogen- and Xenobiotic-Associated Defenses
2012 StandoutNobel
Translation Repression in Human Cells by MicroRNA-Induced Gene Silencing Requires RCK/p54
2006
Regulation of Translation Initiation in Eukaryotes: Mechanisms and Biological Targets
2009 Standout
Composition and Functional Characterization of the Yeast Spliceosomal Penta-snRNP
2002
Translational Control of Long-Lasting Synaptic Plasticity and Memory
2009
CRISPR RNA maturation by trans-encoded small RNA and host factor RNase III
2011 StandoutNatureNobel
TRIBE: Hijacking an RNA-Editing Enzyme to Identify Cell-Specific Targets of RNA-Binding Proteins
2016 StandoutNobel
MicroRNAs: Target Recognition and Regulatory Functions
2009 Standout
The U1 snRNP protein U1C recognizes the 5′ splice site in the absence of base pairing
2002 StandoutNatureNobel
AU-rich elements and associated factors: are there unifying principles?
2005
The question remains: is the spliceosome a ribozyme?
2000
A three-dimensional view of the molecular machinery of RNA interference
2008 StandoutNatureNobel
A novel U2 and U11/U12 snRNP protein that associates with the pre-mRNA branch site
2001
FMRP Stalls Ribosomal Translocation on mRNAs Linked to Synaptic Function and Autism
2011 Standout
Disruption of GW bodies impairs mammalian RNA interference
2005
Ganglion-specific splicing of TRPV1 underlies infrared sensation in vampire bats
2011 StandoutNatureNobel
Functional interaction of a novel 15.5kD [U4/U6middle dotU5] tri-snRNP protein with the 5' stem-loop of U4 snRNA
1999
Metazoan MicroRNAs
2018 Standout
The 100-kDa U5 snRNP protein (hPrp28p) contacts the 5′ splice site through its ATPase site
2001
An RNA Switch at the 5′ Splice Site Requires ATP and the DEAD Box Protein Prp28p
1999
The enzymes and control of eukaryotic mRNA turnover
2004
Searching for ways out of the autism maze: genetic, epigenetic and environmental clues
2006
Stress Granules and Processing Bodies in Translational Control
2018
Trans-splicing in C. elegans generates the negative RNAi regulator ERI-6/7
2008 StandoutNatureNobel
Isolation of an active step I spliceosome and composition of its RNP core
2008 Nature
The EF-G-like GTPase Snu114p Regulates Spliceosome Dynamics Mediated by Brr2p, a DExD/H Box ATPase
2006
MicroRNA-dependent localization of targeted mRNAs to mammalian P-bodies
2005
AU-Rich-Element-Mediated Upregulation of Translation by FXR1 and Argonaute 2
2007
Structure of mammalian eIF3 in the context of the 43S preinitiation complex
2015 StandoutNatureNobel
Hypersensitivity to mGluR5 and ERK1/2 Leads to Excessive Protein Synthesis in the Hippocampus of a Mouse Model of Fragile X Syndrome
2010
Function and Localization of MicroRNAs in Mammalian Cells
2006
Functional and physical interactions between components of the Prp19p-associated complex
2002
Specific Alterations of U1-C Protein or U1 Small Nuclear RNA Can Eliminate the Requirement of Prp28p, an Essential DEAD Box Splicing Factor
2001
Spliceosome disassembly catalyzed by Prp43 and its associated components Ntr1 and Ntr2
2005
Alzheimer's disease
2016 Standout
Crystal Structure of a Complex Between Human Spliceosomal Cyclophilin H and a U4/U6 snRNP-60K Peptide
2003
Insights into RNA Biology from an Atlas of Mammalian mRNA-Binding Proteins
2012 Standout
Messenger RNA Turnover in Eukaryotes: Pathways and Enzymes
2004
GW Bodies, MicroRNAs and the Cell Cycle
2006
Altered Neuronal and Circuit Excitability in Fragile X Syndrome
2015
RNA-binding proteins in human genetic disease
2020
Non-coding RNAs: lessons from the small nuclear and small nucleolar RNAs
2007
AtXRN4 Degrades mRNA in Arabidopsis and Its Substrates Include Selected miRNA Targets
2004
Drosophila Hrp48 Is Required for Mushroom Body Axon Growth, Branching and Guidance
2015
Decay of mRNAs targeted by RISC requires XRN1, the Ski complex, and the exosome
2005
Splicing of a rare class of introns by the U12-dependent spliceosome
2005
Mechanisms of microRNA-mediated gene regulation in animal cells
2007
A role for ubiquitin in the spliceosome assembly pathway
2008
Concerted action of poly(A) nucleases and decapping enzyme in mammalian mRNA turnover
2005
Characterization of U4 and U6 interactions with the 5′ splice site using a S. cerevisiae in vitro trans-splicing system
2001
The chemical repertoire of natural ribozymes
2002 StandoutNatureNobel
Identification by mass spectrometry and functional analysis of novel proteins of the yeast [U4/U6middle dotU5] tri-snRNP
1999
A role for the P-body component GW182 in microRNA function
2005
Prp8 protein: At the heart of the spliceosome
2005
Nuclear Inhibitor of Protein Phosphatase-1 (NIPP1) Directs Protein Phosphatase-1 (PP1) to Dephosphorylate the U2 Small Nuclear Ribonucleoprotein Particle (snRNP) Component, Spliceosome-associated Protein 155 (Sap155)
2008
A crucial role for GW182 and the DCP1:DCP2 decapping complex in miRNA-mediated gene silencing
2005
Signals, synapses, and synthesis: how new proteins control plasticity
2009
Processing bodies require RNA for assembly and contain nontranslating mRNAs
2005
ATP-dependent unwinding of U4/U6 snRNAs by the Brr2 helicase requires the C terminus of Prp8
2008
The Fragile X Mental Retardation Protein in Circadian Rhythmicity and Memory Consolidation
2009
The network of protein–protein interactions within the human U4/U6.U5 tri-snRNP
2006
Small RNAs are modified with N-glycans and displayed on the surface of living cells
2021 StandoutNobel
Control of translation and mRNA degradation by miRNAs and siRNAs: Table 1.
2006 Standout
Mechanisms of post-transcriptional regulation by microRNAs: are the answers in sight?
2008 Standout
Structure of the Mammalian Ribosomal 43S Preinitiation Complex Bound to the Scanning Factor DHX29
2013 StandoutNobel
Repression of protein synthesis by miRNAs: how many mechanisms?
2007
Virus-like particles of the Ty3 retrotransposon assemble in association with P-body components
2005
Identification of Novel Argonaute-Associated Proteins
2005
P bodies: at the crossroads of post-transcriptional pathways
2006
CPEB Interacts with an Ovary-specific eIF4E and 4E-T in Early Xenopus Oocytes
2007
Hepatitis C Virus RNA Functionally Sequesters miR-122
2015 StandoutNobel
Formation of GW bodies is a consequence of microRNA genesis
2006
A conserved RNA-protein complex component involved in physiological germline apoptosis regulation inC. elegans
2005
Carboxy-terminal domain of AID required for its mRNA complex formation in vivo
2009 StandoutNobel
Protein Composition and Electron Microscopy Structure of Affinity-Purified Human Spliceosomal B Complexes Isolated under Physiological Conditions
2006
Structure, function and evolution of seryl-tRNA synthetases: Implications for the evolution of aminoacyl-tRNA synthetases and the genetic code
1995
Spliceosomal Small Nuclear Ribonucleoprotein Particles Repeatedly Cycle through Cajal Bodies
2008
Prediction of the structure of symmetrical protein assemblies
2007 StandoutNobel
RNA–protein analysis using a conditional CRISPR nuclease
2013 StandoutNobel
Edc3p and a glutamine/asparagine-rich domain of Lsm4p function in processing body assembly in Saccharomyces cerevisiae
2007
The Prp19p-Associated Complex in Spliceosome Activation
2003 Science
Purification and electron microscopic visualization of functional human spliceosomes
2002
Stress granules and processing bodies are dynamically linked sites of mRNP remodeling
2005
Control of inositol 1,4,5-trisphosphate-induced Ca2+ release by cytosolic Ca2+
1995 Standout
Nonimmunoglobulin target loci of activation-induced cytidine deaminase (AID) share unique features with immunoglobulin genes
2012 StandoutNobel
The translational regulator CPEB1 provides a link between dcp1 bodies and stress granules
2005
MicroRNAs control translation initiation by inhibiting eukaryotic initiation factor 4E/cap and poly(A) tail function
2005
Eukaryotic mRNA Decapping
2004
Accumulation of Polyadenylated mRNA, Pab1p, eIF4E, and eIF4G with P-Bodies inSaccharomyces cerevisiae
2007
A role for the eIF4E-binding protein 4E-T in P-body formation and mRNA decay
2005
Structure of pyrrolysyl-tRNA synthetase, an archaeal enzyme for genetic code innovation
2007 StandoutNobel
The U1 snRNP Base Pairs with the 5′ Splice Site within a Penta-snRNP Complex
2003
The State of Synapses in Fragile X Syndrome
2009
The ribosomal translocase homologue Snu114p is involved in unwinding U4/U6 RNA during activation of the spliceosome
2002
Cytoplasmic foci are sites of mRNA decay in human cells
2004
Genome-wide comprehensive analysis of human helicases
2011
The Caenorhabditis elegans ARIP-4 DNA helicase couples mitochondrial surveillance to immune, detoxification, and antiviral pathways
2022 StandoutNobel
Specific inhibition of gene expression by small double-stranded RNAs in invertebrate and vertebrate systems
2001 StandoutNobel
Autism-linked neuroligin-3 R451C mutation differentially alters hippocampal and cortical synaptic function
2011 StandoutNobel
Structure of a Multipartite Protein-Protein Interaction Domain in Splicing Factor Prp8 and Its Link to Retinitis Pigmentosa
2007
In vitro reconstitution of the human RISC-loading complex
2008 StandoutNobel
Relief of microRNA-Mediated Translational Repression in Human Cells Subjected to Stress
2006
A cyclophilin functions in pre-mRNA splicing
2002
Translocation events in the evolution of aminoacyl-tRNA synthetases.
1996 StandoutNobel
Purification of the yeast U4/U6⋅U5 small nuclear ribonucleoprotein particle and identification of its proteins
1999
Identification of GW182 and its novel isoform TNGW1 as translational repressors in Ago2-mediated silencing
2008
How Do MicroRNAs Regulate Gene Expression?
2007
CRYO-ELECTRON MICROSCOPY OF SPLICEOSOMAL COMPONENTS
2006
Inhibition of nonsense-mediated mRNA decay (NMD) by a new chemical molecule reveals the dynamic of NMD factors in P-bodies
2007
Allosteric Cascade of Spliceosome Activation
2002
RNA granules
2006
Candidate autism gene screen identifies critical role for cell-adhesion molecule CASPR2 in dendritic arborization and spine development
2012 StandoutNobel
Gawky is a component of cytoplasmic mRNA processing bodies required for early Drosophila development
2006
PERIOD1-Associated Proteins Modulate the Negative Limb of the Mammalian Circadian Oscillator
2005 StandoutScienceNobel
Structural Basis for Double-Stranded RNA Processing by Dicer
2006 StandoutScienceNobel
Toward understanding phosphoseryl-tRNA Cys formation: The crystal structure of Methanococcus maripaludis phosphoseryl-tRNA synthetase
2007 StandoutNobel
The crystal structure of a heptameric archaeal Sm protein: Implications for the eukaryotic snRNP core
2001
Regulation of mRNA Translation and Stability by microRNAs
2010 Standout
Genome-wide comprehensive analysis of human helicases.
2011
Effects of the U1C L13 mutation and temperature regulation of yeast commitment complex formation
2004 StandoutNobel
Proteomics Analysis Reveals Stable Multiprotein Complexes in Both Fission and Budding Yeasts Containing Myb-Related Cdc5p/Cef1p, Novel Pre-mRNA Splicing Factors, and snRNAs
2002
E3 ubiquitin ligase Mindbomb 1 facilitates nuclear delivery of adenovirus genomes
2020 StandoutNobel
Functional Dissection of the Human TNRC6 (GW182-Related) Family of Proteins
2009
Antiviral Protein APOBEC3G Localizes to Ribonucleoprotein Complexes Found in P Bodies and Stress Granules
2006
Structural Insights into Group II Intron Catalysis and Branch-Site Selection
2002 StandoutScienceNobel
Coordinated assembly of human translation initiation complexes by the hepatitis C virus internal ribosome entry site RNA
2004 StandoutNobel
Decapping and Decay of Messenger RNA Occur in Cytoplasmic Processing Bodies
2003 Science
p68 RNA Helicase Is an Essential Human Splicing Factor That Acts at the U1 snRNA-5′ Splice Site Duplex
2002
Works of Tilmann Achsel being referenced
CYFIP1 Coordinates mRNA Translation and Cytoskeleton Remodeling to Ensure Proper Dendritic Spine Formation
2013
mRNPs, polysomes or granules: FMRP in neuronal protein synthesis
2006
Fragile X Mental Retardation Protein (FMRP) Binds Specifically to the Brain Cytoplasmic RNAs BC1/BC200 via a Novel RNA-binding Motif
2005
Coupled In Vitro Import of U snRNPs and SMN, the Spinal Muscular Atrophy Protein
2004
Deficiency of the miR-29a/b-1 cluster leads to ataxic features and cerebellar alterations in mice
2014
FMRP regulates multipolar to bipolar transition affecting neuronal migration and cortical circuitry
2014
The human U5 snRNP 52K protein (CD2BP2) interacts with U5-102K (hPrp6), a U4/U6.U5 tri-snRNP bridging protein, but dissociates upon tri-snRNP formation
2005
The fragile X mental retardation protein–RNP granules show an mGluR-dependent localization in the post-synaptic spines
2007
Endoplasmic Reticulum Stress Induces Apoptosis by an Apoptosome-dependent but Caspase 12-independent Mechanism
2005
A role for eIF4E and eIF4E-transporter in targeting mRNPs to mammalian processing bodies
2005
The Fragile X Syndrome Protein Represses Activity-Dependent Translation through CYFIP1, a New 4E-BP
2008
RNAi knockdown of hPrp31 leads to an accumulation of U4/U6 di‐snRNPs in Cajal bodies
2004
Cooperativity in RNA–protein interactions: the complex is more than the sum of its partners
2016
Crystal Structure of the Human U4/U6 Small Nuclear Ribonucleoprotein Particle-specific SnuCyp-20, a Nuclear Cyclophilin
2000
A doughnut-shaped heteromer of human Sm-like proteins binds to the 3'-end of U6 snRNA, thereby facilitating U4/U6 duplex formation in vitro
1999
Alteration of the micro RNA network during the progression of Alzheimer's disease
2013
Neuronal RNA ‐binding proteins in health and disease
2014
The human homologue of the yeast splicing factor prp6p contains multiple TPR elements and is stably associated with the U5 snRNP via protein-protein interactions
2000
The Human U5-220kD Protein (hPrp8) Forms a Stable RNA-Free Complex with Several U5-Specific Proteins, Including an RNA Unwindase, a Homologue of Ribosomal Elongation Factor EF-2, and a Novel WD-40 Protein
1998
The human U5-200kD DEXH-box protein unwinds U4/U6 RNA duplicesin vitro
1998
The human LSm1-7 proteins colocalize with the mRNA-degrading enzymes Dcp1/2 and Xrn1 in distinct cytoplasmic foci
2002
Identity determinants of human tRNA(Ser): sequence elements necessary for serylation and maturation of a tRNA with a long extra arm.
1993
The human U5 snRNP-specific 100-kD protein is an RS domain-containing, putative RNA helicase with significant homology to the yeast splicing factor Prp28p.
1997
The 20kD protein of human [U4/U6.U5] tri-snRNPs is a novel cyclophilin that forms a complex with the U4/U6-specific 60kD and 90kD proteins.
1998