Thomas Westergard

Loss of C9 ORF 72 impairs autophagy and synergizes with polyQ Ataxin‐2 to induce motor neuron dysfunction and cell death

Mechanisms, regulation and functions of the unfolded protein response

A C9orf72 ALS/FTD Ortholog Acts in Endolysosomal Degradation and Lysosomal Homeostasis

The UPR ER : Sensor and Coordinator of Organismal Homeostasis

MBNL Sequestration by Toxic RNAs and RNA Misprocessing in the Myotonic Dystrophy Brain

The Neurovascular Unit Coming of Age: A Journey through Neurovascular Coupling in Health and Disease

C9orf72 BAC Mouse Model with Motor Deficits and Neurodegenerative Features of ALS/FTD

Amyotrophic lateral sclerosis

Modifiers of C9orf72 dipeptide repeat toxicity connect nucleocytoplasmic transport defects to FTD/ALS

C9orf72 Dipeptide Repeats Impair the Assembly, Dynamics, and Function of Membrane-Less Organelles

The molecular machinery of regulated cell death

Distribution of dipeptide repeat proteins in cellular models and C9orf72 mutation cases suggests link to transcriptional silencing

Quality Control of Membraneless Organelles

Dynamic transcriptomic m6A decoration: writers, erasers, readers and functions in RNA metabolism

Biological Functions of Autophagy Genes: A Disease Perspective

Decoding ALS: from genes to mechanism

GGGGCC repeat expansion in C9orf72 compromises nucleocytoplasmic transport

Considerations and Challenges in Studying Liquid-Liquid Phase Separation and Biomolecular Condensates

Widespread Translational Remodeling during Human Neuronal Differentiation

Artificial intelligence in drug development: present status and future prospects

The Role of Dipeptide Repeats in C9ORF72-Related ALS-FTD

Toxic PR Poly-Dipeptides Encoded by the C9orf72 Repeat Expansion Target LC Domain Polymers

Dipeptide repeat protein inclusions are rare in the spinal cord and almost absent from motor neurons in C9ORF72 mutant amyotrophic lateral sclerosis and are unlikely to cause their degeneration

Quantitative analysis and clinico-pathological correlations of different dipeptide repeat protein pathologies in C9ORF72 mutation carriers

Exosomes, an Unmasked Culprit in Neurodegenerative Diseases

Artificial intelligence in neurodegenerative disease research: use of IBM Watson to identify additional RNA-binding proteins altered in amyotrophic lateral sclerosis

The biology , function , and biomedical applications of exosomes

A C9ORF72/SMCR8-containing complex regulates ULK1 and plays a dual role in autophagy

Cell-to-Cell Transmission of Dipeptide Repeat Proteins Linked to C9orf72-ALS/FTD

Pathogenic determinants and mechanisms of ALS/FTD linked to hexanucleotide repeat expansions in the C9orf72 gene

Antisense Proline-Arginine RAN Dipeptides Linked to C9ORF72-ALS/FTD Form Toxic Nuclear Aggregates that Initiate In Vitro and In Vivo Neuronal Death