Standout Papers
- A Cellular Mechanism of Classical Conditioning in Aplysia : Activity-Dependent Amplification of Presynaptic Facilitation (1983)
- Is contiguity detection in classical conditioning a system or a cellular property? Learning in Aplysia suggests a possible molecular site (1988)
- A Quantitative Study of the Ca2+/Calmodulin Sensitivity of Adenylyl Cyclase in Aplysia, Drosophila, and Rat (1992)
- Two endogenous neuropeptides modulate the gill and siphon withdrawal reflex in Aplysia by presynaptic facilitation involving cAMP-dependent closure of a serotonin-sensitive potassium channel. (1984)
- Classical Conditioning and Sensitization Share Aspects of the Same Molecular Cascade in Aplysia (1983)
Citation Impact
Citing Papers
Evaluation of cellular mechanisms for modulation of calcium transients using a mathematical model of fura-2 Ca2+ imaging in Aplysia sensory neurons
1992
Molecular mechanisms of nociception
2001 StandoutNatureNobel
Spatio-temporal dynamics of cyclic AMP signals in an intact neural circuit
1996 StandoutNatureNobel
A Molecular Switch for the Consolidation of Long‐Term Memory: cAMP‐Inducible Gene Expression
1995 StandoutNobel
Target-dependent structural changes in sensory neurons of aplysia accompany long-term heterosynaptic inhibition
1991
Serotonin Induces Temporally and Mechanistically Distinct Phases of Persistent PKA Activity in Aplysia Sensory Neurons
1998
The Synapse Between LE Sensory Neurons and Gill Motoneurons Makes Only a Small Contribution to the Aplysia Gill‐withdrawal Reflex
1997
Long-term heterosynaptic inhibition in Aplysia
1988 StandoutNatureNobel
Complexity and Diversity of Mammalian Adenylyl Cyclases
1996 Nobel
Imaging terminals of Aplysia sensory neurons demonstrates role of enhanced Ca2+ influx in presynaptic facilitation
1993 StandoutNatureNobel
cAMP and arachidonic acid simulate long-term structural and functional changes produced by neurotransmitters in aplysia sensory neurons
1993 StandoutNobel
Roles of PKA and PKC in facilitation of evoked and spontaneous transmitter release at depressed and nondepressed synapses in aplysia sensory neurons
1992
Persistent and transcriptionally-dependent increase in protein phosphorylation in long-term facilitation ofAplysia sensory neurons
1989 StandoutNatureNobel
Facilitatory and inhibitory transmitters modulate calcium influx during action potentials in Aplysia sensory neurons
1990 StandoutNobel
The Drosophila dunce locus: learning and memory genes in the fly
1991
Synaptotagmin I functions as a calcium regulator of release probability
2001 StandoutNatureNobel
Identification of a cold receptor reveals a general role for TRP channels in thermosensation
2002 StandoutNatureNobel
Neurogenetic Dissection of Learning and Short-Term Memory in Drosophila
1988
NMDA Receptor Activation Increases Cyclic AMP in Area CA1 of the Hippocampus via Calcium/Calmodulin Stimulation of Adenylyl Cyclase
1993
Functions of the LE sensory neurons inAplysia
1997
FMRFamide reverses protein phosphorylation produced by 5-HT and cAMP in Aplysia sensory neurons
1989 StandoutNatureNobel
Parallel Molecular Pathways Mediate Expression of Distinct Forms of Intermediate-Term Facilitation at Tail Sensory–Motor Synapses in Aplysia
2000
Learning to Modulate Transmitter Release: Themes and Variations in Synaptic Plasticity
1993 StandoutNobel
Injection of the cAMP-responsive element into the nucleus of Aplysia sensory neurons blocks long-term facilitation
1990 StandoutNatureNobel
Calcium signaling in cold cells studied in cultured dorsal root ganglion neurons
1999
Cognitive Neuroscience and the Study of Memory
1998
The role of Rab3A in neurotransmitter release
1994 StandoutNatureNobel
Role of guanylyl cyclase and cGMP-dependent protein kinase in long-term potentiation
1994 StandoutNatureNobel
Facilitation, augmentation and potentiation at central synapses
2000
Mushroom bodies and drosophila learning
1993
RIM1α forms a protein scaffold for regulating neurotransmitter release at the active zone
2002 StandoutNatureNobel
A Transient, Neuron-Wide Form of CREB-Mediated Long-Term Facilitation Can Be Stabilized at Specific Synapses by Local Protein Synthesis
1999 StandoutNobel
The CREB family of transcription activators
1992
Serotonergic modulation of two potassium currents in the pleural sensory neurons of Aplysia
1989
Stimuli that produce sensitization lead to elevation of cyclic AMP levels in tail sensory neurons ofAplysia
1986
Loss of calcium/calmodulin responsiveness in adenylate cyclase of rutabaga, a Drosophila learning mutant
1984
The long and the short of long–term memory—a molecular framework
1986 StandoutNatureNobel
Spatially Resolved Dynamics of cAMP and Protein Kinase A Subunits in Aplysia Sensory Neurons
1993 StandoutScienceNobel
Facilitatory and inhibitory transmitters modulate spontaneous transmitter release at cultured Aplysia sensorimotor synapses.
1990
Modulation of spontaneous transmitter release during depression and posttetanic potentiation of Aplysia sensory-motor neuron synapses isolated in culture
1994
Serotonin-Mediated Endocytosis of apCAM: an Early Step of Learning-Related Synaptic Growth in Aplysia
1992 StandoutScienceNobel
Learning by the Aplysia Model System: Lack of Correlation Between Gill and Gill Motor Neurone Responses
1988
Mechanoafferent neurons innervating tail of Aplysia. II. Modulation by sensitizing stimulation
1983 StandoutNobel
Nitric Oxide And Carbon Monoxide Produce Activity-Dependent Long-Term Synaptic Enhancement in Hippocampus
1993 StandoutScienceNobel
Facilitatory transmitters and cAMP can modulate accommodation as well as transmitter release in Aplysia sensory neurons: Evidence for parallel processing in a single cell
1986 StandoutNobel
A Critical Period for Macromolecular Synthesis in Long-Term Heterosynaptic Facilitation in Aplysia
1986 Science
A population of SCP-containing neurons in the buccal ganglion of Aplysia are radula mechanoafferents and receive excitation of central origin
1994
Long-term enhancement produced by activity-dependent modulation of Aplysia sensory neurons
1985
Presynaptic facilitation revisited: state and time dependence
1996
Is there a cell-biological alphabet for simple forms of learning?
1984 StandoutNobel
Are the structural changes in adult Drosophila mushroom bodies memory traces? Studies on biochemical learning mutants.
1987
Parallel processing of short‐term memory for sensitization in Aplysia
1988 StandoutNobel
Message Transmission: Receptor Controlled Adenylate Cyclase System
1984 Science
In vitro classical conditioning of a gill withdrawal reflex in Aplysia: Neural correlates and possible neural mechanisms
1986
Involvement of Presynaptic and Postsynaptic Mechanisms in a Cellular Analog of Classical Conditioning atAplysiaSensory-Motor Neuron Synapses in Isolated Cell Culture
1998 StandoutNobel
Simulation of synaptic depression, posttetanic potentiation, and presynaptic facilitation of synaptic potentials from sensory neurons mediating gill-withdrawal reflex in Aplysia
1985
Invertebrate Learning and Memory: From Behavior to Molecules
1986
Phosphorylation-dependent subcellular translocation of a Ca2+/calmodulin-dependent protein kinase produces an autonomous enzyme in Aplysia neurons.
1985
Associative conditioning analog selectively increases cAMP levels of tail sensory neurons in Aplysia.
1985
DrosophilaMutations that Alter Ionic Conduction Disrupt Acquisition and Retention of a Conditioned Odor Avoidance Response
1986
Adenylyl Cyclase Amino Acid Sequence: Possible Channel- or Transporter-Like Structure
1989 StandoutScienceNobel
Sensitization of the gill and siphon withdrawal reflex of Aplysia: multiple sites of change in the neuronal network
1993
Monosynaptic connections made by the sensory neurons of the gill- and siphon-withdrawal reflex in Aplysia participate in the storage of long-term memory for sensitization
1985 StandoutNobel
Pharmacological Dissociation of Modulatory Effects of Serotonin in Aplysia Sensory Neurons
1991 Science
Impaired Long-Term Potentiation, Spatial Learning, and Hippocampal Development in fyn Mutant Mice
1992 StandoutScienceNobel
Identification of a Peptide Specific for Aplysia Sensory Neurons by PCR-based Differential Screening
1991 StandoutScienceNobel
Short-Term Synaptic Plasticity
2002 Standout
cAMP response element-binding protein is activated by Ca2+/calmodulin- as well as cAMP-dependent protein kinase.
1991 StandoutNobel
Requirement of a Critical Period of Transcription for Induction of a Late Phase of LTP
1994 StandoutScienceNobel
Post-tetanic potentiation inAplysia sensory neurons
1984
Branch-specific heterosynaptic facilitation in Aplysia siphon sensory cells
1984 StandoutNobel
Depletion of serotonin in the nervous system of Aplysia reduces the behavioral enhancement of gill withdrawal as well as the heterosynaptic facilitation produced by tail shock
1989
Contributions of Two Types of Calcium Channels to Synaptic Transmission and Plasticity
1990 StandoutScienceNobel
Distribution of cAMP and cAMP-dependent protein kinases in Aplysia sensory neurons
1987
Defective Responsiveness of Adenylate Cyclase to Forskolin in the Drosophila Memory Mutant rutabaga
1985
Serotonin mimics tail shock in producing transient inhibition in the siphon withdrawal reflex of Aplysia
1991
Effects of interstimulus interval and contingency on classical conditioning of the Aplysia siphon withdrawal reflex
1986
Suppression of calcium current by an endogenous neuropeptide in neurones of Aplysia californica.
1987
Mediation of Classical Conditioning in Aplysia californica by Long-Term Potentiation of Sensorimotor Synapses
1997 Science
Activity-induced changes in synaptic release sites at the crayfish neuromuscular junction
1994
Calcium-Mediated Reduction of Ionic Currents: A Biophysical Memory Trace
1984 Science
Additional component in the cellular mechanism of presynaptic facilitation contributes to behavioral dishabituation in Aplysia.
1986
Genetic dissection of Drosophila adenylate cyclase.
1985
The Contribution of Facilitation of Monosynaptic PSPs to Dishabituation and Sensitization of theAplysiaSiphon Withdrawal Reflex
1999 StandoutNobel
Suppression of sensory to motor synaptic transmission and narrowing of the sensory neurone action potential by arginine vasotocin in Aplysia californica
1987
Effects of cAMP Simulate a Late Stage of LTP in Hippocampal CA1 Neurons
1993 Science
Modulation of ionic currents in Aplysia motor neuron B15 by serotonin, neuropeptides, and second messengers
1989
A Simplified Preparation for Relating Cellular Events to Behavior: Contribution of LE and Unidentified Siphon Sensory Neurons to Mediation and Habituation of theAplysiaGill- and Siphon-Withdrawal Reflex
1997 StandoutNobel
Differential effects of serotonin, FMRFamide, and small cardioactive peptide on multiple, distributed processes modulating sensorimotor synaptic transmission in Aplysia
1992
Are Adult Learning Mechanisms Also Used for Development?
1992 StandoutScienceNobel
Bruchpilot Promotes Active Zone Assembly, Ca 2+ Channel Clustering, and Vesicle Release
2006 StandoutScienceNobel
A novel function for serotonin-mediated short-term facilitation in Aplysia : Conversion of a transient, cell-wide homosynaptic Hebbian plasticity into a persistent, protein synthesis-independent synapse-specific enhancement
2000 StandoutNobel
Differential Classical Conditioning of a Defensive Withdrawal Reflex in Aplysia californica
1983 Science
Are the structural changes in adultDrosophilamushroom bodies memory traces? Studies on biochemical learning mutants
1987
Classical conditioning of the Aplysia siphon-withdrawal reflex exhibits response specificity.
1989 StandoutNobel
Selective short- and long-term effects of serotonin, small cardioactive peptide, and tetanic stimulation on sensorimotor synapses of Aplysia in culture
1990
Tail shock produces inhibition as well as sensitization of the siphon-withdrawal reflex of Aplysia: possible behavioral role for presynaptic inhibition mediated by the peptide Phe-Met-Arg-Phe-NH2.
1987 StandoutNobel
A Simplified Preparation for Relating Cellular Events to Behavior: Mechanisms Contributing to Habituation, Dishabituation, and Sensitization of theAplysiaGill-Withdrawal Reflex
1997 StandoutNobel
Endothelial NOS and the Blockade of LTP by NOS Inhibitors in Mice Lacking Neuronal NOS
1994 StandoutScienceNobel
Neuronal inhibition by the peptide FMRFamide involves opening of S K+ channels
1987 StandoutNatureNobel
Activity-Dependent Enhancement of Presynaptic Inhibition in Aplysia Sensory Neurons
1989 Science
Synaptotagmin: a Calcium Sensor on the Synaptic Vesicle Surface
1992 StandoutScienceNobel
Involvement of protein kinase C in serotonin-induced spike broadening and synaptic facilitation in sensorimotor connections of Aplysia
1992
A genetic pathway for the specification of the vulval cell lineages of Caenorhabditis elegans
1987 StandoutNatureNobel
A MOLECULAR DESCRIPTION OF NERVE TERMINAL FUNCTION
1983
The Molecular Biology of Memory Storage: A Dialogue Between Genes and Synapses
2001 StandoutScienceNobel
Molecular mechanisms of receptor desensitization using the β-adrenergic receptor-coupled adenylate cyclase system as a model
1985 StandoutNatureNobel
Action-potential duration and the modulation of transmitter release from the sensory neurons of Aplysia in presynaptic facilitation and behavioral sensitization
1986 StandoutNobel
The Mating of a Fly
1994 StandoutScienceNobel
Receptive Fields and Properties of A New Cluster Of Mechanoreceptor Neurons Innervating the Mantle Region and the Branchial Cavity of the Marine MolluskAplysia California
1991
Sensitizing stimuli cause translocation of protein kinase C in Aplysia sensory neurons.
1990
Neural and molecular mechanisms underlying information storage in Aplysia: implications for learning and memory
1985
Contribution of polysynaptic pathways in the mediation and plasticity of Aplysia gill and siphon withdrawal reflex: evidence for differential modulation
1992
Target-Dependent Structural Changes Accompanying Long-Term Synaptic Facilitation in Aplysia Neurons
1990 StandoutScienceNobel
Pathway-Specific Synaptic Plasticity: Activity-Dependent Enhancement and Suppression of Long-Term Heterosynaptic Facilitation at Converging Inputs on a Single Target
1997
Molecular Basis for Interactions of G Protein βγ Subunits with Effectors
1998 StandoutScienceNobel
A cellular analysis of inhibition in the siphon withdrawal reflex of Aplysia
1991
Cellular and molecular analysis of associative learning and memory in Hermissenda
1988
FMRFamide modulation of secretory machinery underlying presynaptic inhibition of synaptic transmission requires a pertussis toxin- sensitive G-protein
1991
Long-Term Synaptic Facilitation in the Absence of Short-Term Facilitation in Aplysia Neurons
1993 Science
Hebbian induction of long-term potentiation of Aplysia sensorimotor synapses: partial requirement for activation of an NMDA-related receptor
1994
Differential Induction of Long-Term Synaptic Facilitation by Spaced and Massed Applications of Serotonin at Sensory Neuron Synapses of Aplysia californica
1998
N-methyl-D-aspartate receptor activation increases cAMP levels and voltage-gated Ca2+ channel activity in area CA1 of hippocampus.
1991
Dishabituation and sensitization emerge as separate processes during development in Aplysia
1988
Associative Conditioning of Single Sensory Neurons Suggests a Cellular Mechanism for Learning
1983 Science
Differential effects of cAMP and serotonin on membrane current, action-potential duration, and excitability in somata of pleural sensory neurons of Aplysia
1990
Mutations in the dopa decarboxylase gene affect learning in Drosophila.
1984
Modulation of an NCAM-Related Adhesion Molecule with Long-Term Synaptic Plasticity in Aplysia
1992 StandoutScienceNobel
Works of Thomas W. Abrams being referenced
Evidence that activity dependent facilitation underlying classical conditioning in aplysia involves modulation of the same ionic current as normal presynaptic facilitation
1984
cAMP modulates multiple K+ currents, increasing spike duration and excitability in Aplysia sensory neurons.
1992
Biochemical studies of stimulus convergence during classical conditioning in Aplysia: dual regulation of adenylate cyclase by Ca2+/calmodulin and transmitter
1991
Two endogenous neuropeptides modulate the gill and siphon withdrawal reflex in Aplysia by presynaptic facilitation involving cAMP-dependent closure of a serotonin-sensitive potassium channel.
1984 StandoutNobel
Second messengers involved in the two processes of presynaptic facilitation that contribute to sensitization and dishabituation in Aplysia sensory neurons.
1990
Ca2+/calmodulin sensitivity may be common to all forms of neural adenylate cyclase.
1989
Is contiguity detection in classical conditioning a system or a cellular property? Learning in Aplysia suggests a possible molecular site
1988 StandoutNobel
A Cellular Mechanism of Classical Conditioning in Aplysia : Activity-Dependent Amplification of Presynaptic Facilitation
1983 StandoutScienceNobel
Classical Conditioning and Sensitization Share Aspects of the Same Molecular Cascade in Aplysia
1983 StandoutNobel
Activity-dependent presynaptic facilitation: An associative mechanism inAplysia
1985
Use-Dependent Decline of Paired-Pulse Facilitation atAplysiaSensory Neuron Synapses Suggests a Distinct Vesicle Pool or Release Mechanism
1998
A test of Hebb's postulate at identified synapses which mediate classical conditioning in Aplysia
1984
Reversal of synaptic depression by serotonin at Aplysia sensory neuron synapses involves activation of adenylyl cyclase.
1991