Citation Impact
Citing Papers
Phosphorylation and Regulation of Akt/PKB by the Rictor-mTOR Complex
2005 StandoutScience
Requirement of bic/microRNA-155 for Normal Immune Function
2007 StandoutScience
Mouse models of acute and chronic hepacivirus infection
2017 StandoutScienceNobel
TOR Signaling in Growth and Metabolism
2006 Standout
The Danger Signal, Extracellular ATP, Is a Sensor for an Airborne Allergen and Triggers IL-33 Release and Innate Th2-Type Responses
2011
The effects of IL-6 on CD4 T cell responses
2008
The Drosophila Tuberous Sclerosis Complex Gene Homologs Restrict Cell Growth and Cell Proliferation
2001
mTOR Signaling in Growth Control and Disease
2012 Standout
Inflammation and metabolic disorders
2006 StandoutNature
Mammalian cell size is controlled by mTOR and its downstream targets S6K1 and 4EBP1/eIF4E
2002
MicroRNAs
2004 Standout
The conserved phosphoinositide 3-kinase pathway determines heart size in mice
2000
NFAT dysregulation by increased dosage of DSCR1 and DYRK1A on chromosome 21
2006 StandoutNature
Multiple phases of chondrocyte enlargement underlie differences in skeletal proportions
2013 StandoutNature
Autoregulation of NFATc1/A Expression Facilitates Effector T Cells to Escape from Rapid Apoptosis
2002
Role of IL-6 in Asthma and Other Inflammatory Pulmonary Diseases
2012
Formation of the ∼350-kDa Apg12-Apg5·Apg16 Multimeric Complex, Mediated by Apg16 Oligomerization, Is Essential for Autophagy in Yeast
2002 StandoutNobel
Recognition of NFATp/AP-1 composite elements within genes induced upon the activation of immune cells
1999
AKT/PKB Signaling: Navigating Downstream
2007 Standout
Oncogenic kinase signalling
2001 StandoutNature
Nucleotide signalling during inflammation
2014 StandoutNature
Genetic and biochemical characterization of dTOR, the Drosophila homolog of the target of rapamycin
2000
Central nervous system control of food intake and body weight
2006 StandoutNature
Regulation of translation initiation by FRAP/mTOR
2001
Regulation of mTOR function in response to hypoxia by REDD1 and the TSC1/TSC2 tumor suppressor complex
2004 StandoutNobel
Dpp Gradient Formation in the Drosophila Wing Imaginal Disc
2000
Sensitizing Anthrax Lethal Toxin-resistant Macrophages to Lethal Toxin-induced Killing by Tumor Necrosis Factor-α
2003 StandoutNobel
Genetic analysis of insulin signaling in Drosophila
2002
Shared Principles in NF-κB Signaling
2008 Standout
Systemic Elevation of PTEN Induces a Tumor-Suppressive Metabolic State
2012
Regulation of naive T cell function by the NF-κB2 pathway
2006
TOR, a Central Controller of Cell Growth
2000 Standout
Calcineurin Promotes Hypoxia-inducible Factor 1α Expression by Dephosphorylating RACK1 and Blocking RACK1 Dimerization
2007 StandoutNobel
Transcriptional regulation by calcium, calcineurin, and NFAT
2003 Standout
Proliferation, cell cycle and apoptosis in cancer
2001 StandoutNature
Genetic control of cell size
2000
The genetic control of organ growth: insights from Drosophila
2000
Temsirolimus, Interferon Alfa, or Both for Advanced Renal-Cell Carcinoma
2007 Standout
TSC1 and TSC2 tumor suppressors antagonize insulin signaling in cell growth
2001
Insulin-like Growth Factor 1 Induces Hypoxia-inducible Factor 1-mediated Vascular Endothelial Growth Factor Expression, Which is Dependent on MAP Kinase and Phosphatidylinositol 3-Kinase Signaling in Colon Cancer Cells
2002 StandoutNobel
Analysis of the Catalytic Domain of Phosphatidylinositol 4-Kinase Type II
2002 StandoutNobel
Insulin/IGF and target of rapamycin signaling: a TOR de force in growth control
2003
Transcriptional Regulation of Th2 Differentiation by Inducible Costimulator
2003
mTOR Signaling in Growth, Metabolism, and Disease
2017 Standout
TSC2 Mediates Cellular Energy Response to Control Cell Growth and Survival
2003 Standout
MicroRNA Pathways in Flies and Worms
2003 StandoutNobel
Insulin Receptor Substrate and p55 Orthologous Adaptor Proteins Function in the Caenorhabditis elegans daf-2/Insulin-like Signaling Pathway
2002 StandoutNobel
A mutation in Orai1 causes immune deficiency by abrogating CRAC channel function
2006 StandoutNature
Inhibition of Drosophila EGF receptor activation by the secreted protein Argos
1995 Nature
Modulation of T Cell Cytokine Production by Interferon Regulatory Factor-4
2002
Allosteric Regulation of the Transcription Factor NFAT1 by Multiple Phosphorylation Sites: A Mathematical Analysis
2003
Partners in transcription: NFAT and AP-1
2001 Standout
Osteoclast differentiation and activation
2003 StandoutNature
Insulin signalling and the regulation of glucose and lipid metabolism
2001 StandoutNature
Methods in Mammalian Autophagy Research
2010 Standout
Cell-autonomous regulation of cell and organ growth in Drosophila by Akt/PKB
1999
The translational inhibitor 4E-BP is an effector of PI(3)K/Akt signalling and cell growth in Drosophila
2001
SREBP Activity Is Regulated by mTORC1 and Contributes to Akt-Dependent Cell Growth
2008
NFAT1 and NFAT2 are positive regulators of IL-4 gene transcription
2002
Drosophila PTEN Regulates Cell Growth and Proliferation through PI3K-Dependent and -Independent Pathways
2000
The Role of the Prothoracic Gland in Determining Critical Weight for Metamorphosis in Drosophila melanogaster
2005
Control of TH17/Treg Balance by Hypoxia-Inducible Factor 1
2011 StandoutNobel
Insights into social insects from the genome of the honeybee Apis mellifera
2006 StandoutNature
The PtdIns(3,4)P2 phosphatase INPP4A is a suppressor of excitotoxic neuronal death
2010 StandoutNatureNobel
Regulation of the Murine Nfatc1 Gene by NFATc2
2002
NFAT proteins: key regulators of T-cell development and function
2005
PTEN function in mammalian cell size regulation
2002
AKT/PKB Signaling: Navigating the Network
2017 Standout
Repertoires of Autophagy in the Pathogenesis of Ocular Diseases
2015 Standout
Regulation of cellular growth by the Drosophila target of rapamycin dTOR
2000
The Hallmarks of Aging
2013 Standout
Programmed Autophagy in the Drosophila Fat Body Is Induced by Ecdysone through Regulation of the PI3K Pathway
2004
Akt and Bcl-xL Promote Growth Factor-independent Survival through Distinct Effects on Mitochondrial Physiology
2001
Cancer-related inflammation
2008 StandoutNature
Large Scale Gene Expression Analysis of Osteoclastogenesisin Vitro and Elucidation of NFAT2 as a Key Regulator
2002
The functions of animal microRNAs
2004 StandoutNatureNobel
Ras1 Promotes Cellular Growth in the Drosophila Wing
2000
Akt1/PKBα Is Required for Normal Growth but Dispensable for Maintenance of Glucose Homeostasis in Mice
2001
Drosophila's Insulin/PI3-Kinase Pathway Coordinates Cellular Metabolism with Nutritional Conditions
2002
Both integrated and differential regulation of components of the IL-2/IL-2 receptor system
2006
Drosophila Tsc1 Functions with Tsc2 to Antagonize Insulin Signaling in Regulating Cell Growth, Cell Proliferation, and Organ Size
2001
Manipulating Immune Responses with Immunosuppressive Agents that Target NFAT
2000
Synthesis and Function of 3-Phosphorylated Inositol Lipids
2001 Standout
Do growth and cell division rates determine cell size in multicellular organisms?
2000
Angiopoietin-2, a Natural Antagonist for Tie2 That Disrupts in vivo Angiogenesis
1997 StandoutScience
The transcription factor NFATc2 controls IL-6–dependent T cell activation in experimental colitis
2008
DAF-16 Target Genes That Control C. elegans Life-Span and Metabolism
2003 StandoutScienceNobel
Regulation of interferon-γ gene expression by nuclear factor of activated T cells
2001
Inhibition of Th2 Differentiation and GATA-3 Expression by BCL-6
2003
Inhibition of NFATx Activation by an Oligopeptide: Disrupting the Interaction of NFATx with Calcineurin
2001
The bantam Gene Regulates Drosophila Growth
2002
Hypoxia-Inducible Factor 1α Is a Critical Downstream Mediator for Hypoxia-Induced Mitogenic Factor (FIZZ1/RELMα)–Induced Pulmonary Hypertension
2015 StandoutNobel
An IL-4-independent and CD25-mediated function of c-maf in promoting the production of Th2 cytokines
2002
Sustained NFAT Signaling Promotes a Th1-Like Pattern of Gene Expression in Primary Murine CD4+ T Cells
2002
Autophagy as a Regulated Pathway of Cellular Degradation
2000 StandoutScience
Differentiation of Effector CD4 T Cell Populations
2010 Standout
Early onset of neoplasia in the prostate and skin of mice with tissue-specific deletion of Pten
2004 StandoutNobel
The PI3K–PDK1 connection: more than just a road to PKB
2000
Morphogen gradient interpretation
2001 StandoutNatureNobel
Distinct influences of peptide-MHC quality and quantity on in vivo T-cell responses
2012 StandoutNobel
Works of Thomas Twardzik being referenced
Regulation of imaginal disc cell size, cell number and organ size by Drosophila class IA phosphoinositide 3-kinase and its adaptor
1999
The role of NF-AT transcription factors in T cell activation and differentiation11We dedicate this review to Prof. Dr. Rigomar Rieger (Gatersleben), a great scientist and man, on the occasion of his 70th birthday. One of us (E.S.) had the pleasure of working in his department.
2000
The Drosophila giant lens gene plays a dual role in eye and optic lobe development: Inhibition of differentiation of ommatidial cells and interference in photoreceptor axon guidance
1994
Induction of NFATc2 Expression by Interleukin 6 Promotes T Helper Type 2 Differentiation
2002
The Interleukin 2 Receptor α Chain/CD25 Promoter Is a Target for Nuclear Factor of Activated T Cells
1998