Standout Papers
Citation Impact
Citing Papers
Differential Antigen Processing by Dendritic Cell Subsets in Vivo
2007 StandoutScienceNobel
Genome-wide CRISPR screens reveal a specific ligand for the glycan-binding immune checkpoint receptor Siglec-7
2021 StandoutNobel
Topological control of cytokine receptor signaling induces differential effects in hematopoiesis
2019 StandoutScienceNobel
Caenorhabditis elegans ADAR editing and the ERI-6/7/MOV10 RNAi pathway silence endogenous viral elements and LTR retrotransposons
2020 StandoutNobel
X-linked cholestasis in mouse due to mutations of the P4-ATPase ATP11C
2011 StandoutNobel
Selective delivery of β cell antigen to dendritic cells in vivo leads to deletion and tolerance of autoreactive CD8 + T cells in NOD mice
2008 StandoutNobel
Chromatin state dynamics during blood formation
2014 Science
Designed protein logic to target cells with precise combinations of surface antigens
2020 StandoutScienceNobel
Efficient human iPS cell derivation by a non-integrating plasmid from blood cells with unique epigenetic and gene expression signatures
2011
An integrated encyclopedia of DNA elements in the human genome
2012 StandoutNature
Lineage-specific and single-cell chromatin accessibility charts human hematopoiesis and leukemia evolution
2016
Identification of an MHC class I-restricted autoantigen in type 1 diabetes by screening an organ-specific cDNA library
1999
Young blood reverses age-related impairments in cognitive function and synaptic plasticity in mice
2014
Cut and trim: generating MHC class I peptide ligands
2001
Directional DNA Methylation Changes and Complex Intermediate States Accompany Lineage Specificity in the Adult Hematopoietic Compartment
2011
Logic-Gated ROR1 Chimeric Antigen Receptor Expression Rescues T Cell-Mediated Toxicity to Normal Tissues and Enables Selective Tumor Targeting
2019
CD22 blockade restores homeostatic microglial phagocytosis in ageing brains
2019 StandoutNatureNobel
Human ADAR1 Prevents Endogenous RNA from Triggering Translational Shutdown
2018 StandoutNobel
Evolution of the cancer genome
2012
C-type lectins in immunity and homeostasis
2018
A unique regulatory phase of DNA methylation in the early mammalian embryo
2012 Nature
Discrete Proteolytic Intermediates in the MHC Class I Antigen Processing Pathway and MHC I–Dependent Peptide Trimming in the ER
1999
Human umbilical cord plasma proteins revitalize hippocampal function in aged mice
2017 Nature
Genome-wide DNA methylation profiles in hematopoietic stem and progenitor cells reveal overrepresentation of ETS transcription factor binding sites
2012
Generation of Antigen-Specific, LacZ-Inducible T-Cell Hybrids
2003
ATP11C is critical for the internalization of phosphatidylserine and differentiation of B lymphocytes
2011
Ultrasensitive fluorescent proteins for imaging neuronal activity
2013 StandoutNature
Poor Repair of Skeletal Muscle in Aging Mice Reflects a Defect in Local, Interleukin-33-Dependent Accumulation of Regulatory T Cells
2016
DNA methylation: roles in mammalian development
2013 Standout
Haematopoietic stem cells and early lymphoid progenitors occupy distinct bone marrow niches
2013 Nature
Cell type–specific DNA methylation at intragenic CpG islands in the immune system
2011
The bone marrow niche for haematopoietic stem cells
2014 StandoutNature
Ageing, neurodegeneration and brain rejuvenation
2016 Nature
Biological Functions of Autophagy Genes: A Disease Perspective
2019 Standout
Two-Photon Calcium Imaging Reveals an Odor-Evoked Map of Activity in the Fly Brain
2003 StandoutNobel
Microbial Stimulation Fully Differentiates Monocytes to DC-SIGN/CD209+ Dendritic Cells for Immune T Cell Areas
2010 StandoutNobel
Sources of diversity in T cell epitope discovery
2011
Molecular Determinants of Regulatory T Cell Development: The Essential Roles of Epigenetic Changes
2013 StandoutNobel
Tuning Cytokine Receptor Signaling by Re-orienting Dimer Geometry with Surrogate Ligands
2015
Engineering CAR-T cells: Design concepts
2015
Reprogramming of T Cells from Human Peripheral Blood
2010
Taking dendritic cells into medicine
2007 StandoutNatureNobel
Mechanism-driven biomarkers to guide immune checkpoint blockade in cancer therapy
2016 Standout
A new paradigm for hematopoietic cell lineages: revision of the classical concept of the myeloid–lymphoid dichotomy
2009
DNA Methylation Dynamics during In Vivo Differentiation of Blood and Skin Stem Cells
2012
The causes and consequences of genetic heterogeneity in cancer evolution
2013 StandoutNature
Restoring function in exhausted CD8 T cells during chronic viral infection
2005 StandoutNatureNobel
PU.1 Is Required for the Developmental Progression of Multipotent Progenitors to Common Lymphoid Progenitors
2018
Cancer immunotherapy comes of age
2011 StandoutNature
Identification of transcriptional regulators in the mouse immune system
2013
Charting histone modifications and the functional organization of mammalian genomes
2010
Identification of genetic elements that autonomously determine DNA methylation states
2011
Innate production of TH2 cytokines by adipose tissue-associated c-Kit+Sca-1+ lymphoid cells
2009 StandoutNature
A promoter DNA demethylation landscape of human hematopoietic differentiation
2011
The role of senescent cells in ageing
2014 StandoutNature
Epigenetic modifications and human disease
2010 Standout
The Hallmarks of Aging
2013 Standout
Epigenetic modifications in pluripotent and differentiated cells
2010
Adoptive-cell-transfer therapy for the treatment of patients with cancer
2003
Comprehensive Integration of Single-Cell Data
2019 Standout
Cdc42 Activity Regulates Hematopoietic Stem Cell Aging and Rejuvenation
2012
26 S Proteasome-mediated Production of an Authentic Major Histocompatibility Class I-restricted Epitope from an Intact Protein Substrate
1999
Organoid single-cell genomic atlas uncovers human-specific features of brain development
2019 StandoutNatureNobel
Innate immunity and intestinal microbiota in the development of Type 1 diabetes
2008 StandoutNature
A high signal-to-noise Ca2+ probe composed of a single green fluorescent protein
2001
Fluorescent Indicators for Cyclic GMP Based on Cyclic GMP-Dependent Protein Kinase Iα and Green Fluorescent Proteins
2000
Immunization with HIV Gag targeted to dendritic cells followed by recombinant New York vaccinia virus induces robust T-cell immunity in nonhuman primates
2011 StandoutNobel
Tissue Tregs
2016
An Efficient Nonviral Method to Generate Integration-Free Human-Induced Pluripotent Stem Cells from Cord Blood and Peripheral Blood Cells
2012 StandoutNobel
SPAS-1 (stimulator of prostatic adenocarcinoma-specific T cells)/SH3GLB2: A prostate tumor antigen identified by CTLA-4 blockade
2008 StandoutNobel
Genetically encoded reporters of protein kinase A activity reveal impact of substrate tethering
2001 StandoutNobel
DEC-205 receptor on dendritic cells mediates presentation of HIV gag protein to CD8 + T cells in a spectrum of human MHC I haplotypes
2007 StandoutNobel
Immuno-Navigator, a batch-corrected coexpression database, reveals cell type-specific gene networks in the immune system
2016 StandoutNobel
The MHC Class I-Restricted Immune Response to HIV-gag in BALB/c Mice Selects a Single Epitope That Does Not Have a Predictable MHC-Binding Motif and Binds to Kd Through Interactions Between a Glutamine at P3 and Pocket D
1998
Reconstructing the DNA Methylation Maps of the Neandertal and the Denisovan
2014 StandoutScienceNobel
Comparable T helper 1 (Th1) and CD8 T-cell immunity by targeting HIV gag p24 to CD8 dendritic cells within antibodies to Langerin, DEC205, and Clec9A
2011 StandoutNobel
Intramembrane Proteolysis of Signal Peptides: An Essential Step in the Generation of HLA-E Epitopes
2001
Epigenetic control of thymic Treg‐cell development
2014 StandoutNobel
The Caenorhabditis elegans ARIP-4 DNA helicase couples mitochondrial surveillance to immune, detoxification, and antiviral pathways
2022 StandoutNobel
Genome-wide promoter DNA methylation dynamics of human hematopoietic progenitor cells during differentiation and aging
2011
RNA editing by ADAR1 prevents MDA5 sensing of endogenous dsRNA as nonself
2015 Science
Spatiotemporal dynamics of guanosine 3′,5′-cyclic monophosphate revealed by a genetically encoded, fluorescent indicator
2001 StandoutNobel
Detection of T cell responses to a ubiquitous cellular protein in autoimmune disease
2014 StandoutScienceNobel
Proenkephalin+regulatory T cells expanded by ultraviolet B exposure maintain skin homeostasis with a healing function
2020 StandoutNobel
DEGRADATION OF CELL PROTEINS AND THE GENERATION OF MHC CLASS I-PRESENTED PEPTIDES
1999
Immunotherapy: Bewitched, Bothered, and Bewildered No More
2004 StandoutScienceNobel
The Caenorhabditis elegans IMPAS gene, imp-2, is essential for development and is functionally distinct from related presenilins
2004 StandoutNobel
The Ubiquitin-Proteasome Proteolytic Pathway: Destruction for the Sake of Construction
2002 StandoutNobel
CAR T cell immunotherapy for human cancer
2018 StandoutScience
The Essential Functions of Adipo-osteogenic Progenitors as the Hematopoietic Stem and Progenitor Cell Niche
2010
Multiple Click-Selective tRNA Synthetases Expand Mammalian Cell-Specific Proteomics
2018 StandoutNobel
DNA methyltransferase 1 and DNA methylation patterning contribute to germinal center B-cell differentiation
2011
Antibody to Langerin/CD207 localizes large numbers of CD8α + dendritic cells to the marginal zone of mouse spleen
2009 StandoutNobel
Thimet Oligopeptidase (EC 3.4.24.15), a Novel Protein on the Route of MHC Class I Antigen Presentation
1999
CELL BIOLOGY OF ANTIGEN PROCESSING IN VITRO AND IN VIVO
2005
Works of Thomas Serwold being referenced
Reductive isolation from bone marrow and blood implicates common lymphoid progenitors as the major source of thymopoiesis
2008
Restoring Systemic GDF11 Levels Reverses Age-Related Dysfunction in Mouse Skeletal Muscle
2014 Science
Young, Proliferative Thymic Epithelial Cells Engraft and Function in Aging Thymuses
2015
Gene Expression Commons: An Open Platform for Absolute Gene Expression Profiling
2012
Does nitric oxide regulate capacitative Ca influx in HEK 293 cells?
1997
The Autoimmunity-Associated Gene CLEC16A Modulates Thymic Epithelial Cell Autophagy and Alters T Cell Selection
2015
Growth Differentiation Factor 11 Is a Circulating Factor that Reverses Age-Related Cardiac Hypertrophy
2013 Standout
Reading within the lines: naturally processed peptides displayed by MHC class I molecules
1998
Ly6d marks the earliest stage of B-cell specification and identifies the branchpoint between B-cell and T-cell development
2009
All the peptides that fit: the beginning, the middle, and the end of the MHC class I antigen‐processing pathway
2005
MHC Class I Molecules Can Direct Proteolytic Cleavage of Antigenic Precursors in the Endoplasmic Reticulum
2001
ERAAP customizes peptides for MHC class I molecules in the endoplasmic reticulum
2002 Nature
ER aminopeptidases generate a unique pool of peptides for MHC class I molecules
2001
Comprehensive methylome map of lineage commitment from haematopoietic progenitors
2010 Nature
Specific Proteolytic Cleavages Limit the Diversity of the Pool of Peptides Available to MHC Class I Molecules in Living Cells
1999
Flk2+ common lymphoid progenitors possess equivalent differentiation potential for the B and T lineages
2008
The mouse mammary tumor virusenvgene is the source of a CD8+T-cell-stimulating peptide presented by a major histocompatibility complex class I molecule in a murine thymoma
1996
Early TCR Expression and Aberrant T Cell Development in Mice with Endogenous Prerearranged T Cell Receptor Genes
2007
T-cell receptor-driven lymphomagenesis in mice derived from a reprogrammed T cell
2010
Producing Nature’s Gene-Chips: The Generation of Peptides for Display by MHC Class I Molecules
2002
Presentation of endogenous peptide/MHC class I complexes is profoundly influenced by specific C-terminal flanking residues
1995