Citation Impact
Citing Papers
Hierarchical Mechanisms for Direct Reprogramming of Fibroblasts to Neurons
2013 StandoutNobel
The role of chromatin accessibility in directing the widespread, overlapping patterns of Drosophila transcription factor binding
2011
An integrated encyclopedia of DNA elements in the human genome
2012 StandoutNature
Yeast heat shock factor is an essential DNA-binding protein that exhibits temperature-dependent phosphorylation
1988
Molecular cloning and expression of a hexameric Drosophila heat shock factor subject to negative regulation
1990
Heat-inducible DNA Binding of Purified Heat Shock Transcription Factor 1
1995
Attenuated stress responses in young and old human lymphocytes
1997
HIV-1 rev regulation involves recognition of non-Watson-Crick base pairs in viral RNA
1991 StandoutNobel
Trimerization of a yeast transcriptional activator via a coiled-coil motif
1989
Structure of the Histone Acetyltransferase Hat1
1998 StandoutNobel
Expression of the SV40 promoter in fission yeast: Identification and characterization of an AP-1-like factor
1988 StandoutNobel
Yeast heat shock factor contains separable transient and sustained response transcriptional activators
1990
Structural Basis of Transcription: Role of the Trigger Loop in Substrate Specificity and Catalysis
2006 StandoutNobel
MAP kinase activation during heat shock in quiescent and exponentially growing mammalian cells
1993
Multiple functions of Drosophila heat shock transcription factor in vivo
1997
A Model for the Cooperative Binding of Eukaryotic Regulatory Proteins to Nucleosomal Target Sites
1996
Firefly luciferase mutants as sensors of proteome stress
2011
Role of chromatin structure in the regulation of transcription by RNA polymerase II
1993
Transcript cleavage factors GreA and GreB act as transient catalytic components of RNA polymerase
2003
Architectural variations of inducible eukaryotic promoters: Preset and remodeling chromatin structures
1994
Twenty-Five Years of the Nucleosome, Fundamental Particle of the Eukaryote Chromosome
1999 StandoutNobel
RSC, an Essential, Abundant Chromatin-Remodeling Complex
1996 StandoutNobel
Stress–inducible responses and heat shock proteins: New pharmacologic targets for cytoprotection
1998
Is hsp70 the cellular thermometer?
1991
Disruption of the HSF3 gene results in the severe reduction of heat shock gene expression and loss of thermotolerance
1998
A Mutant Drosophila Homolog of Mammalian Clock Disrupts Circadian Rhythms and Transcription of period and timeless
1998 StandoutNobel
Control of NF- B-dependent Transcriptional Responses by Chromatin Organization
2009
The language of covalent histone modifications
2000 StandoutNature
Expression cloning of a cDNA encoding a retinoblastoma-binding protein with E2F-like properties
1992 StandoutNobel
Regulation of the heat shock transcriptional response: cross talk between a family of heat shock factors, molecular chaperones, and negative regulators
1998 Standout
SWI/SNF Stimulates the Formation of Disparate Activator-Nucleosome Complexes but Is Partially Redundant with Cooperative Binding
1997
The C-terminal region of Drosophila heat shock factor (HSF) contains a constitutively functional transactivation domain
1996
Targeted Disruption of Heat Shock Transcription Factor 1 Abolishes Thermotolerance and Protection against Heat-inducible Apoptosis
1998
Celastrols as Inducers of the Heat Shock Response and Cytoprotection
2004 Standout
Repression of Heat Shock Transcription Factor HSF1 Activation by HSP90 (HSP90 Complex) that Forms a Stress-Sensitive Complex with HSF1
1998
Nucleosomes Unfold Completely at a Transcriptionally Active Promoter
2003 StandoutNobel
Complex expression of murine heat shock transcription factors
1995
Crystal structure of the nucleosome core particle at 2.8 Å resolution
1997 StandoutNature
The origin of pattern and polarity in the Drosophila embryo
1992 StandoutNobel
A mediator required for activation of RNA polymerase II transcription in vitro
1991 StandoutNatureNobel
Position and orientation of the globular domain of linker histone H5 on the nucleosome
1998 StandoutNatureNobel
Conservation of a stress response: human heat shock transcription factors functionally substitute for yeast HSF
1997
Induction of Phosphoglycerate Kinase 1 Gene Expression by Hypoxia
1996
Nucleosome displacement in transcription: Figure 1.
2006
Transcriptional regulation by the immediate early protein of pseudorabies virus during in vitro nucleosome assembly
1988
Continuous and widespread roles for the Swi-Snf complex in transcription
1999
The Transcriptional regulation of heat shock genes: A plethora of heat shock factors and regulatory conditions
1996
The yeast heat shock transcription factor contains a transcriptional activation domain whose activity is repressed under nonshock conditions
1990
The complexities of eukaryotic transcription initiation: regulation of preinitiation complex assembly
1991
Histone Octamer Transfer by a Chromatin-Remodeling Complex
1999 StandoutNobel
Protein folding in the cell
1992 StandoutNature
A novel kinase cascade triggered by stress and heat shock that stimulates MAPKAP kinase-2 and phosphorylation of the small heat shock proteins
1994 StandoutNobel
Similarities between prokaryotic and eukaryotic cyclic AMP-responsive promoter elements
1989 Nature
Jak-STAT Pathways and Transcriptional Activation in Response to IFNs and Other Extracellular Signaling Proteins
1994 StandoutScience
Isolation of the gene encoding the S. cerevisiae heat shock transcription factor
1988
Pioneer transcription factors: establishing competence for gene expression
2011
Nucleosomes, DNA-binding proteins, and DNA sequence modulate retroviral integration target site selection
1992
Purification and Characterization of Hypoxia-inducible Factor 1
1995 StandoutNobel
Negative regulation of the heat shock transcriptional response by HSBP1
1998
The unfolded-protein-response pathway in yeast
1994
Longevity, Stress Response, and Cancer in Aging Telomerase-Deficient Mice
1999 StandoutNobel
The Hsf world: classification and properties of plant heat stress transcription factors
1996
Identification of cellular proteins that can interact specifically with the T/ElA-binding region of the retinoblastoma gene product
1991 StandoutNobel
Suppression of inflammation by a synthetic histone mimic
2010 StandoutNatureNobel
Oxidants, oxidative stress and the biology of ageing
2000 StandoutNature
Multisite phosphorylation provides sophisticated regulation of transcription factors
2002
The Role of Chromatin during Transcription
2007 Standout
Sensing stress and responding to stress
1996
Two cDNAs for Tomato Heat Stress Transcription Factors
1993
Phosphorylation of serine 230 promotes inducible transcriptional activity of heat shock factor 1
2001
Formation of nuclear HSF1 granules varies depending on stress stimuli
2000
Different Thresholds in the Responses of Two Heat Shock Transcription Factors, HSF1 and HSF3
1997
Trimerization of the heat shock transcription factor by a triple-stranded .alpha.-helical coiled-coil
1992
Mechanism of Protein Access to Specific DNA Sequences in Chromatin: A Dynamic Equilibrium Model for Gene Regulation
1995
The fission yeast cdc18+ gene product couples S phase to START and mitosis
1993 StandoutNobel
Effects of activation-defective TBP mutations on transcription initiation in yeast
1994 StandoutNatureNobel
Expression of Heat Shock Factor 2 in Mouse Testis: Potential Role as a Regulator of Heat-Shock Protein Gene Expression during Spermatogenesis1
1994
Quantitative Models of the Mechanisms That Control Genome-Wide Patterns of Transcription Factor Binding during Early Drosophila Development
2011
Induction temperature of human heat shock factor is reprogrammed in a Drosophila cell environment
1993 Nature
Cloning of the p50 DNA binding subunit of NF-κB: Homology to rel and dorsal
1990 Nobel
Injection of the cAMP-responsive element into the nucleus of Aplysia sensory neurons blocks long-term facilitation
1990 StandoutNatureNobel
Identification of a DNA binding factor involved in cell-cycle control of the yeast HO gene
1989
A positive role for histone acetylation in transcription factor access to nucleosomal DNA
1993
Multiple extracellular activities in Drosophila egg perivitelline fluid are required for establishment of embryonic dorsal-ventral polarity
1992 StandoutNobel
Stress-induced oligomerization and chromosomal relocalization of heat-shock factor
1991 Nature
Human SWI/SNF Interconverts a Nucleosome between Its Base State and a Stable Remodeled State
1998
cactus, a gene involved in dorsoventral pattern formation of Drosophila, is related to the IκB gene family of vertebrates
1992 StandoutNobel
Activation of Heat Shock Factor 1 DNA Binding Precedes Stress-induced Serine Phosphorylation
1996
Mechanisms of intracellular protein transport
1994 StandoutNatureNobel
Isolation and characterization of six heat shock transcription factor cDNA clones from soybean
1995
Irresistible force meets immovable object: Transcription and the nucleosome
1991 StandoutNobel
Protein traffic on the heat shock promoter: Parking, stalling, and trucking along
1993
Promoter specificity and deletion analysis of three heat stress transcription factors of tomato
1993
Function and regulation of heat shock factor 2 during mouse embryogenesis
1997
Expression of heat shock protein 70 is altered by age and diet at the level of transcription.
1993
Activation of Drosophila heat shock factor: conformational change associated with a monomer-to-trimer transition.
1993
Repression of the Heat Shock Factor 1 Transcriptional Activation Domain Is Modulated by Constitutive Phosphorylation
1997
Human Heat Shock Factors 1 and 2 Are Differentially Activated and Can Synergistically Induce hsp70 Gene Transcription
1994
Purification and characterization of a heat-shock element binding protein from yeast.
1987
NMR structure determination reveals that the homeodomain is connected through a flexible linker to the main body in the Drosophila Antennapedia protein.
1992 StandoutNobel
Sequence analysis of the cis-regulatory regions of the bithorax complex of Drosophila.
1995 StandoutNobel
Direct Sensing of Heat and Oxidation by Drosophila Heat Shock Transcription Factor
1998
The transactivation domain of Pho4 is required for nucleosome disruption at the PHO5 promoter.
1994
DNA binding of heat shock factor to the heat shock element is insufficient for transcriptional activation in murine erythroleukemia cells.
1990
The human heat shock protein hsp70 interacts with HSF, the transcription factor that regulates heat shock gene expression.
1992
Mutation of the mouse klotho gene leads to a syndrome resembling ageing.
1997 Standout
Hormone induces binding of receptors and transcription factors to a rearranged nucleosome on the MMTV promoter in vivo.
1995
Attenuation of the heat shock response in HeLa cells is mediated by the release of bound heat shock transcription factor and is modulated by changes in growth and in heat shock temperatures.
1991
Novel cysteine-rich motif and homeodomain in the product of the Caenorhabditis elegans cell lineage gene lin-II
1990 StandoutNatureNobel
PER Protein Interactions and Temperature Compensation of a Circadian Clock in Drosophila
1995 StandoutScienceNobel
Complex modes of heat shock factor activation.
1990
Identification of the C-terminal activator domain in yeast heat shock factor: independent control of transient and sustained transcriptional activity.
1993
Regulation of Heat Shock Factor Trimer Formation: Role of a Conserved Leucine Zipper
1993 Science
Selection of new HSF1 and HSF2 DNA-binding sites reveals difference in trimer cooperativity.
1994
Coordinate changes in heat shock element-binding activity and HSP70 gene transcription rates in human cells.
1988
Molecular cloning and expression of a human heat shock factor, HSF1.
1991
(CT)n (GA)n repeats and heat shock elements have distinct roles in chromatin structure and transcriptional activation of the Drosophila hsp26 gene.
1993
Repression of human heat shock factor 1 activity at control temperature by phosphorylation.
1996
A histone-binding protein, nucleoplasmin, stimulates transcription factor binding to nucleosomes and factor-induced nucleosome disassembly.
1994
A short element required for turning off heat shock transcription factor: evidence that phosphorylation enhances deactivation.
1994
(CT)n (GA)n Repeats and Heat Shock Elements Have Distinct Roles in Chromatin Structure and Transcriptional Activation of the Drosophila hsp26 Gene
1993
Cytoplasmic activation of ISGF3, the positive regulator of interferon-alpha-stimulated transcription, reconstituted in vitro.
1989
Small molecule probes to quantify the functional fraction of a specific protein in a cell with minimal folding equilibrium shifts
2014 StandoutNobel
The DNA-Binding Properties of Two Heat Shock Factors, HSF1 and HSF3, Are Induced in the Avian Erythroblast Cell Line HD6
1995
Binding of disparate transcriptional activators to nucleosomal DNA is inherently cooperative
1995
Interaction between heat shock factor and hsp70 is insufficient to suppress induction of DNA-binding activity in vivo.
1994
Activation of human heat shock genes is accompanied by oligomerization, modification, and rapid translocation of heat shock transcription factor HSF1.
1993
In vitro activation of heat shock transcription factor DNA-binding by calcium and biochemical conditions that affect protein conformation.
1990
Nucleosome Core Displacement in Vitro via a Metastable Transcription Factor-Nucleosome Complex
1992 Science
Decoding the nucleosome
1993
Stimulation of GAL4 Derivative Binding to Nucleosomal DNA by the Yeast SWI/SNF Complex
1994 Science
ALTERATION OF NUCLEOSOME STRUCTURE AS A MECHANISM OF TRANSCRIPTIONAL REGULATION
1998
Purification and Properties of Drosophila Heat Shock Activator Protein
1987 Science
Chromatin remodeling by DNA bending, not twisting
2005 StandoutNobel
Regulation of Inducible and Tissue-Specific Gene Expression
1987 Science
Activation of yeast RNA polymerase II transcription by a thymidine-rich upstream element in vitro.
1989 StandoutNobel
Arachidonate is a potent modulator of human heat shock gene transcription.
1994
Multiple Layers of Regulation of Human Heat Shock Transcription Factor 1
1995
Hypoxia-inducible factor-1 modulates gene expression in solid tumors and influences both angiogenesis and tumor growth
1997 StandoutNobel
Transcriptional Regulation in Mammalian Cells by Sequence-Specific DNA Binding Proteins
1989 StandoutScience
The DNA-Binding Activity of the Human Heat Shock Transcription Factor Is Regulated In Vivo by hsp70
1993
Differential Display of Eukaryotic Messenger RNA by Means of the Polymerase Chain Reaction
1992 StandoutScience
Roles of the heat shock transcription factors in regulation of the heat shock response and beyond
2001
Effect of Sodium Salicylate on the Human Heat Shock Response
1992 Science
Three tomato genes code for heat stress transcription factors with a region of remarkable homology to the DNA-binding domain of the yeast HSF.
1990
Chromatin remodeling by nucleosome disassembly in vitro
2006 StandoutNobel
Characterization of a novel chicken heat shock transcription factor, heat shock factor 3, suggests a new regulatory pathway.
1993
Heat shock gene regulation by nascent polypeptides and denatured proteins: hsp70 as a potential autoregulatory factor
1992
Activation of the DNA-Binding Ability of Human Heat Shock Transcription Factor 1 May Involve the Transition from an Intramolecular to an Intermolecular Triple-Stranded Coiled-Coil Structure
1994
The Carboxyl-Terminal Transactivation Domain of Heat Shock Factor 1 Is Negatively Regulated and Stress Responsive
1995
Tissue-Dependent Expression of Heat Shock Factor 2 Isoforms with Distinct Transcriptional Activities
1995
A human homologue of Saccharomyces cerevisiae SNF2/SWI2 and Drosophila brm genes potentiates transcriptional activation by the glucocorticoid receptor.
1993
Activation of Heat Shock Factor 2 during Hemin-Induced Differentiation of Human Erythroleukemia Cells
1992
Nucleosome Translational Position, Not Histone Acetylation, Determines TFIIIA Binding to Nucleosomal Xenopus laevis 5S rRNA Genes
1998
Activation of heat shock gene transcription by heat shock factor 1 involves oligomerization, acquisition of DNA-binding activity, and nuclear localization and can occur in the absence of stress.
1993
Hemin-induced transcriptional activation of the HSP70 gene during erythroid maturation in K562 cells is due to a heat shock factor-mediated stress response.
1989
Expression of Heat Shock Protein 70 is Altered by Age and Diet at the Level of Transcription
1993
Regulation of chemical stress-induced hsp70 gene expression in murine L929 cells
1994
HSP90 Interacts with and Regulates the Activity of Heat Shock Factor 1 in Xenopus Oocytes
1998
Cloning and characterization of two mouse heat shock factors with distinct inducible and constitutive DNA-binding ability.
1991
Activation of Heat Shock Transcription Factor 3 by c-Myb in the Absence of Cellular Stress
1997 Science
HSF4, a New Member of the Human Heat Shock Factor Family Which Lacks Properties of a Transcriptional Activator
1997
Crystal Structure of the DNA Binding Domain of the Heat Shock Transcription Factor
1994 Science
Persistent Site-Specific Remodeling of a Nucleosome Array by Transient Action of the SWI/SNF Complex
1996 Science
Structural analysis of the RSC chromatin-remodeling complex
2002 StandoutNobel
Nucleosome disruption and enhancement of activator binding by a human SW1/SNF complex
1994 Nature
HSF1 granules: a novel stress-induced nuclear compartment of human cells
1997
Heat shock factor is regulated differently in yeast and HeLa cells
1987 Nature
A Heat Shock Transcription Factor with Reduced Activity Suppresses a Yeast HSP70 Mutant
1995
Cells in Stress: Transcriptional Activation of Heat Shock Genes
1993 Science
Stimulation of Transcription Factor Binding and Histone Displacement by Nucleosome Assembly Protein 1 and Nucleoplasmin Requires Disruption of the Histone Octamer
1995
Works of Thomas Schuetz being referenced
Activation in vitro of sequence-specific DNA binding by a human regulatory factor
1988 Nature
Heat-Inducible Human Factor That Binds to a Human hsp70 Promoter
1987
Regulation of heat shock factor in Schizosaccharomyces pombe more closely resembles regulation in mammals than in Saccharomyces cerevisiae.
1991
In vitro activation of purified human heat shock factor by heat
1995
Facilitated binding of GAL4 and heat shock factor to nucleosomal templates: differential function of DNA-binding domains.
1991
A Heat Shock-Responsive Domain of Human HSF1 That Regulates Transcription Activation Domain Function
1995
Isolation of a cDNA for HSF2: evidence for two heat shock factor genes in humans.
1991
Heat-inducible human factor that binds to a human hsp70 promoter.
1987