Citation Impact
Citing Papers
Oxidative Stress
2017 Standout
Targeting Nrf2 with the triterpenoid CDDO- imidazolide attenuates cigarette smoke-induced emphysema and cardiac dysfunction in mice
2008
Nrf2-mediated neuroprotection in the MPTP mouse model of Parkinson's disease: Critical role for the astrocyte
2009
Ferroptosis regulation by the NGLY1/NFE2L1 pathway
2022 StandoutNobel
Bardoxolone methyl (BARD) ameliorates ischemic AKI and increases expression of protective genes Nrf2, PPARγ, and HO-1
2011
Reactive Oxygen Species in Inflammation and Tissue Injury
2013 Standout
Epidemic Inflammation: Pondering Obesity
2008
Nrf2 the rescue: Effects of the antioxidative/electrophilic response on the liver
2010
Acidity promotes tumour progression by altering macrophage phenotype in prostate cancer
2019
Platelet factor 4–induced T H 1-T reg polarization suppresses antitumor immunity
2024 StandoutScienceNobel
Astrocytes: biology and pathology
2009 Standout
In vivo quantitative imaging of tumor pH by nanosonophore assisted multispectral photoacoustic imaging
2017
Bardoxolone conjugation enables targeted protein degradation of BRD4
2020
An Assembled Nanocomplex for Improving both Therapeutic Efficiency and Treatment Depth in Photodynamic Therapy
2018
Bardoxolone Methyl and Kidney Function in CKD with Type 2 Diabetes
2011
Mechanisms of activation of the transcription factor Nrf2 by redox stressors, nutrient cues, and energy status and the pathways through which it attenuates degenerative disease
2015
Nrf2 degron-fused reporter system: a new tool for specific evaluation of Nrf2 inducers
2011
Nrf2, a Guardian of Healthspan and Gatekeeper of Species Longevity
2010
Novel synthetic pyridyl analogues of CDDO-Imidazolide are useful new tools in cancer prevention
2015
Inflammation and Cancer: Triggers, Mechanisms, and Consequences
2019 Standout
Different Susceptibility to the Parkinson's Toxin MPTP in Mice Lacking the Redox Master Regulator Nrf2 or Its Target Gene Heme Oxygenase-1
2010
Microbial tryptophan catabolites in health and disease
2018 Standout
Nrf2-Keap1 signaling in oxidative and reductive stress
2018 Standout
The hormetic dose-response mechanism: Nrf2 activation
2021
Identification of Novel microRNAs in Post-Transcriptional Control of Nrf2 Expression and Redox Homeostasis in Neuronal, SH-SY5Y Cells
2012
Regulation and Functions of the ER-Associated Nrf1 Transcription Factor
2022 StandoutNobel
Neuroprotective Effects of the Triterpenoid, CDDO Methyl Amide, a Potent Inducer of Nrf2-Mediated Transcription
2009
Cystamine protects from 3-nitropropionic acid lesioning via induction of nf-e2 related factor 2 mediated transcription
2010
Role of Nrf2 in prevention of high-fat diet-induced obesity by synthetic triterpenoid CDDO-Imidazolide
2009
Dual Chemodrug-Loaded Single-Walled Carbon Nanohorns for Multimodal Imaging-Guided Chemo-Photothermal Therapy of Tumors and Lung Metastases
2018
Targeting oxidative stress in disease: promise and limitations of antioxidant therapy
2021 Standout
Dimethyl fumarate and the oleanane triterpenoids, CDDO-imidazolide and CDDO-methyl ester, both activate the Nrf2 pathway but have opposite effects in the A/J model of lung carcinogenesis
2015
The role of the immune system in neurodegenerative disorders: Adaptive or maladaptive?
2014
The Science of Stroke: Mechanisms in Search of Treatments
2010 Standout
Fumaric acid esters exert neuroprotective effects in neuroinflammation via activation of the Nrf2 antioxidant pathway
2011 Standout
An RNA-Sequencing Transcriptome and Splicing Database of Glia, Neurons, and Vascular Cells of the Cerebral Cortex
2014 Standout
Role of Nrf2/HO-1 system in development, oxidative stress response and diseases: an evolutionarily conserved mechanism
2016 Standout
The Nrf2–ARE Pathway
2008
Nonresolving Inflammation
2010 Standout
Contrast agents for molecular photoacoustic imaging
2016
Natural product-derived pharmacological modulators of Nrf2/ARE pathway for chronic diseases
2013
The Triterpenoid CDDO-Imidazolide Confers Potent Protection against Hyperoxic Acute Lung Injury in Mice
2009
Induction of Cytoprotective Pathways Is Central to the Extension of Lifespan Conferred by Multiple Longevity Pathways
2012 StandoutNobel
Air pollution: mechanisms of neuroinflammation and CNS disease
2009 Standout
Understanding the metabolic fate and assessing the biosafety of MnO nanoparticles by metabonomic analysis
2013
Genetic or Pharmacologic Amplification of Nrf2 Signaling Inhibits Acute Inflammatory Liver Injury in Mice
2008
The transcription factor Nrf2 as a new therapeutic target in Parkinson's disease
2009
Halofuginone enhances the chemo-sensitivity of cancer cells by suppressing NRF2 accumulation
2016
Triterpenoids CDDO-ethyl amide and CDDO-trifluoroethyl amide improve the behavioral phenotype and brain pathology in a transgenic mouse model of Huntington's disease
2010
Reactive oxygen species (ROS) as pleiotropic physiological signalling agents
2020 Standout
The Nrf2 triterpenoid activator, CDDO-imidazolide, protects kidneys from ischemia–reperfusion injury in mice
2013
Multiscale photoacoustic tomography using reversibly switchable bacterial phytochrome as a near-infrared photochromic probe
2015
Gold Nanocage-Photosensitizer Conjugates for Dual-Modal Image-Guided Enhanced Photodynamic Therapy
2014
Targeting NRF2 signaling for cancer chemoprevention
2009
Oxidative damage and the Nrf2-ARE pathway in neurodegenerative diseases
2014
HMGB1 promotes ductular reaction and tumorigenesis in autophagy-deficient livers
2018
Oxidative Stress in Cancer
2020 Standout
Topical application of the synthetic triterpenoid RTA 408 activates Nrf2 and induces cytoprotective genes in rat skin
2013
Macrophages as regulators of tumour immunity and immunotherapy
2019 Standout
PROTAC targeted protein degraders: the past is prologue
2022 Standout
The Nrf2 regulatory network provides an interface between redox and intermediary metabolism
2014 Standout
Synthetic Oleanane Triterpenoids: Multifunctional Drugs with a Broad Range of Applications for Prevention and Treatment of Chronic Disease
2012
Defining roles of specific reactive oxygen species (ROS) in cell biology and physiology
2022 Standout
The impact of environmental metals in young urbanites’ brains
2012
A cytoprotective perspective on longevity regulation
2013 StandoutNobel
Developing drug molecules for therapy with carbon monoxide
2012
The Nrf2-ARE Pathway: A Valuable Therapeutic Target for the Treatment of Neurodegenerative Diseases
2012
Deletion of Keap1 in the Lung Attenuates Acute Cigarette Smoke–Induced Oxidative Stress and Inflammation
2009
Proteomic Analysis Shows Synthetic Oleanane Triterpenoid Binds to mTOR
2011
Therapeutic targeting of the NRF2 and KEAP1 partnership in chronic diseases
2019 Standout
NLRP3 inflammasome activation: the convergence of multiple signalling pathways on ROS production?
2010 Standout
Synthetic Triterpenoids Attenuate Cytotoxic Retinal Injury: Cross-talk between Nrf2 and PI3K/AKT Signaling through Inhibition of the Lipid Phosphatase PTEN
2009
Genetic versus chemoprotective activation of Nrf2 signaling: overlapping yet distinct gene expression profiles between Keap1 knockout and triterpenoid-treated mice
2009
Frequent epigenetics inactivation of KEAP1 gene in non-small cell lung cancer
2011
Role of microglial redox balance in modulation of neuroinflammation
2009
Transcriptional Regulation of the AP-1 and Nrf2 Target Gene Sulfiredoxin
2009
Triterpenoids and rexinoids as multifunctional agents for the prevention and treatment of cancer
2007
Brain Energy Metabolism: Focus on Astrocyte-Neuron Metabolic Cooperation
2011 Standout
Engineered Nanoparticles for Drug Delivery in Cancer Therapy
2014 Standout
Nrf2: control of sensitivity to carcinogens
2011
Nrf2 activation improves experimental rheumatoid arthritis
2023 StandoutNobel
Lipid Oxidation and Peroxidation in CNS Health and Disease: From Molecular Mechanisms to Therapeutic Opportunities
2009
NRF2 and Hypoxia-Inducible Factors: Key Players in the Redox Control of Systemic Iron Homeostasis
2020
Targeting Nrf2-Mediated Gene Transcription by Extremely Potent Synthetic Triterpenoids Attenuate Dopaminergic Neurotoxicity in the MPTP Mouse Model of Parkinson's Disease
2012
Pharmacological Targeting of the Transcription Factor Nrf2 at the Basal Ganglia Provides Disease Modifying Therapy for Experimental Parkinsonism
2011
Frequency Modulated Translocational Oscillations of Nrf2 Mediate the Antioxidant Response Element Cytoprotective Transcriptional Response
2014
Inhibition of the NRF2/KEAP1 Axis: A Promising Therapeutic Strategy to Alter Redox Balance of Cancer Cells
2021
Repurposing the NRF2 Activator Dimethyl Fumarate as Therapy Against Synucleinopathy in Parkinson's Disease
2016
The Nrf2/ARE Pathway as a Potential Therapeutic Target in Neurodegenerative Disease
2008
Nrf2-Mediated Transcriptional Induction of Antioxidant Response in Mouse Embryos Exposed to Ethanol in vivo : Implications for the Prevention of Fetal Alcohol Spectrum Disorders
2008
Nrf2, the Master Regulator of Anti-Oxidative Responses
2017
Manganese and Parkinson’s Disease: A Critical Review and New Findings
2010
Photothermal therapy and photoacoustic imaging via nanotheranostics in fighting cancer
2018 Standout
Nanomaterials for In Vivo Imaging
2017
Unmixing Molecular Agents From Absorbing Tissue in Multispectral Optoacoustic Tomography
2013
Role of Nrf2 in Oxidative Stress and Toxicity
2013 Standout
Multicomponent Plasmonic Nanoparticles: From Heterostructured Nanoparticles to Colloidal Composite Nanostructures
2019
Diabetic Downregulation of Nrf2 Activity via ERK Contributes to Oxidative Stress–Induced Insulin Resistance in Cardiac Cells In Vitro and In Vivo
2011
Mesoscopic and Macroscopic Optoacoustic Imaging of Cancer
2015
Reactive oxygen species in the tumor niche triggers altered activation of macrophages and immunosuppression: Role of fluoxetine
2015
Preparation of a Cross-Linked Porous Protein Crystal Containing Ru Carbonyl Complexes as a CO-Releasing Extracellular Scaffold
2014 StandoutNobel
NRF2 Modulates Aryl Hydrocarbon Receptor Signaling: Influence on Adipogenesis
2007
Diabetic Cardiomyopathy
2018 Standout
Distinct Regulations of HO-1 Gene Expression for Stress Response and Substrate Induction
2021
Nanotechnology for Multimodal Synergistic Cancer Therapy
2017 Standout
Microglia Function in the Central Nervous System During Health and Neurodegeneration
2017 Standout
Gold-Nanorods-Based Gene Carriers with the Capability of Photoacoustic Imaging and Photothermal Therapy
2016
Genetic activation of Nrf2 signaling is sufficient to ameliorate neurodegenerative phenotypes in aDrosophilamodel of Parkinson’s disease
2011
A genomic screen for activators of the antioxidant response element
2007
Uptake and Accumulation of Polystyrene Microplastics in Zebrafish (Danio rerio) and Toxic Effects in Liver
2016 Standout
Complete Protection against Aflatoxin B1-Induced Liver Cancer with a Triterpenoid: DNA Adduct Dosimetry, Molecular Signature, and Genotoxicity Threshold
2014
The KEAP1-NRF2 System: a Thiol-Based Sensor-Effector Apparatus for Maintaining Redox Homeostasis
2018 Standout
Gold Nanorods: The Most Versatile Plasmonic Nanoparticles
2021
Role of the K eap1/N rf2 pathway in neurodegenerative diseases
2015
Nrf2 activation in the treatment of neurodegenerative diseases: a focus on its role in mitochondrial bioenergetics and function
2016
High Levels of Nrf2 Determine Chemoresistance in Type II Endometrial Cancer
2010
SCF/β-TrCP Promotes Glycogen Synthase Kinase 3-Dependent Degradation of the Nrf2 Transcription Factor in a Keap1-Independent Manner
2011 Standout
Mechanisms of Diabetic Complications
2013 Standout
Myeloid Lineage–Specific Deletion of Antioxidant System Enhances Tumor Metastasis
2014
Reactive Oxygen Species (ROS)-Based Nanomedicine
2019 Standout
The Nrf2–ARE cytoprotective pathway in astrocytes
2009
Sulforaphane-Induced Klf9/Prdx6 Axis Acts as a Molecular Switch to Control Redox Signaling and Determines Fate of Cells
2019
Coordination Modulation Method To Prepare New Metal–Organic Framework-Based CO-Releasing Materials
2018 StandoutNobel
Magnetite pollution nanoparticles in the human brain
2016 Standout
Lipid Peroxidation: Production, Metabolism, and Signaling Mechanisms of Malondialdehyde and 4-Hydroxy-2-Nonenal
2014 Standout
Analogs of bardoxolone methyl worsen diabetic nephropathy in rats with additional adverse effects
2012
Advances in real-time multispectral optoacoustic imaging and its applications
2015
Emerging Targets in Photopharmacology
2016 StandoutNobel
NRF2-mediated Notch pathway activation enhances hematopoietic reconstitution following myelosuppressive radiation
2014
Stress-Activated Cap'n'collar Transcription Factors in Aging and Human Disease
2010
Investigating the functional link between TMEM165 and SPCA1
2019 StandoutNobel
Cellular uptake of nanoparticles: journey inside the cell
2017 Standout
Genetic Analysis of Hierarchical Regulation for Gata1 and NF-E2 p45 Gene Expression in Megakaryopoiesis
2010
Biocompatible conjugated polymer nanoparticles for highly efficient photoacoustic imaging of orthotopic brain tumors in the second near-infrared window
2017
Photothermal Nanomaterials: A Powerful Light-to-Heat Converter
2023 Standout
Photothermal Effect Enhanced Cascade-Targeting Strategy for Improved Pancreatic Cancer Therapy by Gold Nanoshell@Mesoporous Silica Nanorod
2017
Systemic Activation of NRF2 Alleviates Lethal Autoimmune Inflammation in Scurfy Mice
2017 StandoutNobel
Advanced optoacoustic methods for multiscale imaging of in vivo dynamics
2017
Works of Thomas Sardella being referenced
Targeting Acidity in Pancreatic Adenocarcinoma: Multispectral Optoacoustic Tomography Detects pH-Low Insertion Peptide Probes In Vivo
2015
Deep-Tissue Reporter-Gene Imaging with Fluorescence and Optoacoustic Tomography: A Performance Overview
2014
Fast Multispectral Optoacoustic Tomography (MSOT) for Dynamic Imaging of Pharmacokinetics and Biodistribution in Multiple Organs
2012
Effects of Chronic Manganese Exposure on Glutamatergic and GABAergic Neurotransmitter Markers in the Nonhuman Primate Brain
2009
Measures of kidney function by minimally invasive techniques correlate with histological glomerular damage in SCID mice with adriamycin-induced nephropathy
2015
Absence of Nrf2 or Its Selective Overexpression in Neurons and Muscle Does Not Affect Survival in ALS-Linked Mutant hSOD1 Mouse Models
2013
Multimodal Molecular Imaging of Integrin αvβ3 for In Vivo Detection of Pancreatic Cancer
2014
Multispectral Opto-acoustic Tomography (MSOT) of the Brain and Glioblastoma Characterization
2012
Semi-quantitative Multispectral Optoacoustic Tomography (MSOT) for volumetric PK imaging of gastric emptying
2014
In vivo modulation of the Parkinsonian phenotype by Nrf2
2006
Increased APLP1 expression and neurodegeneration in the frontal cortex of manganese‐exposed non‐human primates
2008
Structural and Functional Analysis of Intact Hair Follicles and Pilosebaceous Units by Volumetric Multispectral Optoacoustic Tomography
2015
Impairment of nigrostriatal dopamine neurotransmission by manganese is mediated by pre‐synaptic mechanism(s): implications to manganese‐induced parkinsonism
2008
VMAT2 and dopamine neuron loss in a primate model of Parkinson’s disease
2007
Manganese Neurotoxicity: Lessons Learned from Longitudinal Studies in Nonhuman Primates
2008
Pharmacodynamic characterization of chemopreventive triterpenoids as exceptionally potent inducers of Nrf2-regulated genes
2007
Preventing Plasmon Coupling between Gold Nanorods Improves the Sensitivity of Photoacoustic Detection of Labeled Stem Cells in Vivo
2016
Correction: Absence of Nrf2 or Its Selective Overexpression in Neurons and Muscle Does Not Affect Survival in ALS-Linked Mutant hSOD1 Mouse Models
2013
Comprehensive studies of pharmacokinetics and biodistribution of indocyanine green and liposomal indocyanine green by multispectral optoacoustic tomography
2014
Multiscale Multispectral Optoacoustic Tomography by a Stationary Wavelet Transform Prior to Unmixing
2014
Multispectral optoacoustic tomography at 64, 128, and 256 channels
2014
Multispectral optoacoustic and MRI coregistration for molecular imaging of orthotopic model of human glioblastoma
2016
Metastatic status of sentinel lymph nodes in melanoma determined noninvasively with multispectral optoacoustic imaging
2015
Liposome–Gold Nanorod Hybrids for High-Resolution Visualization Deep in Tissues
2012