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Effects of short-term cortisol infusion on growth hormone-releasing hormone stimulation of growth hormone release in sheep
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Differential effects of in vivo estrogen administration on hypothalamic growth hormone releasing hormone and somatostatin gene expression
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Regulation of growth hormone-releasing hormone and somatostatin from perifused, bovine hypothalamic slices. III. Reciprocal feedback between growth hormone-releasing hormone and somatostatin
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Nutritional Regulation of the Insulin-Like Growth Factors*
1994
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Thyroid hormone modulation of the hypothalamic growth hormone (GH)-releasing factor-pituitary GH axis in the rat.
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New insights into the regulation of somatotrope function using genetic and transgenic models
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Inhibition of Hypothalamic Somatostatin Release by β-Adrenergic Antagonists*
1990
Nature of Altered Growth Hormone Secretion in Hyperthyroidism*
1991
The Growth-Hormone-Releasing Hormone Receptor: Signal Transduction, Gene Expression, and Physiological Function in Growth Regulationa
2006
Natural Substrates of Dipeptidyl Peptidase IV
2002
Urocortin, a mammalian neuropeptide related to fish urotensin I and to corticotropin-releasing factor
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2001
Dipeptidyl‐peptidase IV hydrolyses gastric inhibitory polypeptide, glucagon‐like peptide‐1(7–36)amide, peptide histidine methionine and is responsible for their degradation in human serum
1993
Acromegaly
1990
Paradoxical Enhancement of Pituitary Growth Hormone (GH) Responsiveness to GH-Releasing Factor in the Face of High Somatostatin Tone*
1989
Effect of chronic metabolic acidosis on the growth hormone/IGF-1 endocrine axis: New cause of growth hormone insensitivity in humans
1997
The Impact of Gonadal Steroid Hormone Action on Growth Hormone Secretion During Childhood and Adolescence*
1992
Thyroid Hormone and the Cardiovascular System
2001 Standout
Chronic growth hormone (GH) hypersecretion induces reciprocal and reversible changes in mRNA levels from hypothalamic GH-releasing hormone and somatostatin neurons in the rat.
1993
Masculinization of growth hormone (GH) secretory pattern by dihydrotestosterone is associated with augmentation of hypothalamic somatostatin and GH-releasing hormone mRNA levels in ovariectomized adult rats
1992
Dipeptide Phosphonates as Inhibitors of Dipeptidyl Peptidase IV
1994
Growth Hormone-Releasing Hormone: Synthesis and Signaling
1995
Influence of Food Deprivation in the Rat on Hypothalamic Expression of Growth Hormone-Releasing Factor and Somatostatin*
1990
Epidemiology of Acromegaly
1999
Molecular Mechanisms of Depression: Perspectives on New Treatment Strategies
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Glucagon-like peptide-1-(9-36) amide is a major metabolite of glucagon-like peptide-1-(7-36) amide after in vivo administration to dogs, and it acts as an antagonist on the pancreatic receptor
1996
In vivo inhibition of dipeptidyl peptidase IV activity by pro-pro-diphenyl-phosphonate (prodipine)
1997
Attenuation of spontaneous, nocturnal growth hormone secretion in children with hypothyroidism and its correlation with plasma insulin-like growth factor I concentrations
1989
Neuroendocrine and physiological regulation of intake with particular reference to domesticated ruminant animals
2008
The Pit-1 transcription factor gene is a candidate for the murine Snell dwarf mutation
1990
Neuroendocrine control of pulsatile growth hormone release in the human: relationship with gender
1998
BASIC COUNTERPOINT: Mechanisms and Pathways of Gonadal Steroid Modulation of Growth Hormone Secretion*
1992
Relationship between hypophyseal portal GHRH and somatostatin and peripheral GH levels in the conscious sheep
1994
A low dose euglycemic infusion of recombinant human insulin-like growth factor I rapidly suppresses fasting-enhanced pulsatile growth hormone secretion in humans.
1993
Ghrelin induces adiposity in rodents
2000 StandoutNature
Effect of tianeptine on the hypothalamic somatotropic axis in the conscious sheep
1994
Alogliptin after Acute Coronary Syndrome in Patients with Type 2 Diabetes
2013 Standout
The incretin system: glucagon-like peptide-1 receptor agonists and dipeptidyl peptidase-4 inhibitors in type 2 diabetes
2006 Standout
Growth hormone-releasing hormone and somatostatin concentrations in the hypophysial portal blood of conscious sheep during the infusion of growth hormone-releasing peptide-6
1996
Identification of a seven transmembrane helix receptor for corticotropin-releasing factor and sauvagine in mammalian brain
1993
Pharmaceutical and medicinal significance of sulfur (SVI)-Containing motifs for drug discovery: A critical review
2018 Standout
Effect of ingestion of glucose on GH and TSH secretion: Evidence for stimulation of somatostatin release from the hypothalamus by acute hyperglycemia in normal man and its impairment in acromegalic patients
1989
Endogenous growth hormone (GH)-releasing hormone is required for GH responses to pharmacological stimuli.
1996
PTP1B as a drug target: recent developments in PTP1B inhibitor discovery
2007
Effect of Restricted Feeding on the Relationship Between Hypophysial Portal Concentrations of Growth Hormone (GH)-Releasing Factor and Somatostatin, and Jugular Concentrations of GH in Ovariectomized Ewes*
1991
Neuroendocrine Control of Growth Hormone Secretion
1991
International Union of Pharmacology. XXXV. The Glucagon Receptor Family
2003
β-Adrenergic Modulation of Growth Hormone (GH) Autofeedback on Sleep-Associated and Pharmacologically Induced GH Secretion*
1989
Thyroid hormones and growth hormone secretion
1992
Defective Hypothalamic Growth Hormone (GH)-Releasing Hormone Activity May Contribute to Declining GH Secretion with Age in Man1
1997
Dipeptidyl peptidase 4 is a functional receptor for the emerging human coronavirus-EMC
2013 StandoutNature
Ambient Temperature Regulation of Apoptosis in Brown Adipose Tissue
1998
Suppression of growth hormone (GH) secretion by a selective GH-releasing hormone (GHRH) antagonist. Direct evidence for involvement of endogenous GHRH in the generation of GH pulses.
1993
The effects of pituitary stalk transection, hypophysectomy and thyroid hormone status on insulin-like growth factor 2-, growth hormone releasing hormone-, and somatostatin mRNA prevalence in rat brain
1992
Perinatal Growth Hormone (GH) Physiology: Effect of GH-Releasing Factor on Maternal and Fetal Secretion of Pituitary and Placental GH*
1990
Cysteamine-Induced Enhancement of Growth Hormone- Releasing Factor (GRF) Immunoreactivity in Arcuate Neurons: Morphological Evidence for Putative Somatostatin/GRF Interactions within Hypothalamus*
1990
The Physiology of Glucagon-like Peptide 1
2007 Standout
Mechanisms of Antineoplastic Action of Somatostatin Analogs
1998 Nobel
Production of parathyroid hormone‐related protein by cultured human myeloma cells
1994 StandoutNobel
Sequence-Specific Gene Detection with a Gold Electrode Modified with DNA Probes and an Electrochemically Active Dye
1994
[26] Deconvolution analysis of hormone data
1992
Invited review: Body condition score and its association with dairy cow productivity, health, and welfare
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GHRH receptor of little mice contains a missense mutation in the extracellular domain that disrupts receptor function
1993
GROWTH HORMONE NEUROREGULATION AND ITS ALTERATIONS IN DISEASE STATES
1988
Antioxidant enzyme levels as a function of growth state in cell culture
1995
The Amyloid State of Proteins in Human Diseases
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Somatostatin receptor subtype specificity in human fetal pituitary cultures. Differential role of SSTR2 and SSTR5 for growth hormone, thyroid-stimulating hormone, and prolactin regulation.
1997
What We Talk About When We Talk About Fat
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A mutation in the human leptin receptor gene causes obesity and pituitary dysfunction
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Iodine-deficiency disorders
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1999
Hypothalamic regulation of growth hormone secretion during food deprivation in the rat
1993
Negative feedback regulation of pulsatile growth hormone secretion by insulin-like growth factor I. Involvement of hypothalamic somatostatin.
1994
Mutant cells defective in poly(ADP-ribose) synthesis due to stable alterations in enzyme activity or substrate availability
1989
Expression of sstr1 and sstr2 in Rat Hypothalamus: Correlation with Receptor Binding and Distribution of Growth Hormone Regulatory Peptides
2007
The multifunctional or moonlighting protein CD26/DPPIV
2003
Differential impact of age, sex steroid hormones, and obesity on basal versus pulsatile growth hormone secretion in men as assessed in an ultrasensitive chemiluminescence assay.
1995
Fluorometric assay of DNA in cartilage explants using Hoechst 33258
1988
Sulfur(VI) Fluoride Exchange (SuFEx): Another Good Reaction for Click Chemistry
2014 StandoutNobel
The Effect of Hypophysectomy and Growth Hormone Administration on Pre-Prosomatostatin Messenger Ribonucleic Acid in the Periventricular Nucleus of the Rat Hypothalamus*
1988
Immobilization of specific monoclonal antibody on Au nanoparticles for hGH detection by electrochemical impedance spectroscopy
2009
[7] Model-independent quantification of measurement error: Empirical estimation of discrete variance function profiles based on standard curves
1994
Structure of proline iminopeptidase from Xanthomonas campestris pv. citri: a prototype for the prolyl oligopeptidase family
1998
Microfluidics: reframing biological enquiry
2015
The Intermediate Lactotroph: A Morphologically Distinct, Ghrelin-Responsive Pituitary Cell in the Dwarf (dw/dw) Rat
2005
Gene expression of hypothalamic somatostatin, growth hormone releasing factor, and their pituitary receptors in hypothyroidism.
1996
Studies on Prolactin and Growth Hormone Gene Expression in the Pituitary Gland of Spontaneous Dwarf Rats*
1989
Intrahypothalamic Neurohormonal Interactions in the Control of Growth Hormone Secretion
2007
Insulin-like growth factors I and II expression in the healing wound
1992
Dipeptidyl-Peptidase IV from Bench to Bedside: An Update on Structural Properties, Functions, and Clinical Aspects of the Enzyme DPP IV
2003
RAMPs regulate the transport and ligand specificity of the calcitonin-receptor-like receptor
1998 StandoutNature
Conformation of one- and two-chain high molecular weight urokinase analyzed by small-angle neutron scattering and vacuum ultraviolet circular dichroism
1991 StandoutNobel
Multilineage Potential of Adult Human Mesenchymal Stem Cells
1999 StandoutScience
Hypothalamic Growth Hormone Secretagogue-Receptor (GHS-R) Expression Is Regulated by Growth Hormone in the Rat
1997
Effects of iodine deficiency on insulin‐like growth factor‐I, insulin‐like growth factor‐binding protein‐3 levels and height attainment in malnourished children
1996
Pathophysiology of the Neuroregulation of Growth Hormone Secretion in Experimental Animals and the Human*
1998 Standout
Integrins, Oncogenes, and Anchorage Independence
1997
Ames dwarf mice exhibit somatotrope commitment but lack growth hormone-releasing factor response.
1995
Uptake of thyroid hormones in neonatal rat cardiac myocytes.
1996
Dominant dwarfism in transgenic rats by targeting human growth hormone (GH) expression to hypothalamic GH-releasing factor neurons.
1996
Growth Hormone Receptor Antagonists: Discovery, Development, and Use in Patients with Acromegaly
2002
Regulation of hypothalamic somatostatin, growth hormone-releasing hormone, and growth hormone receptor messenger ribonucleic acid by glucocorticoids.
1996
Mice carrying null mutations of the genes encoding insulin-like growth factor I (Igf-1) and type 1 IGF receptor (Igf1r)
1993 Standout
Regulation of the endothelial cell urokinase-type plasminogen activator receptor. Evidence for cyclic AMP-dependent and protein kinase C-dependent pathways.
1993 StandoutNobel
Gold Nanoparticles: Assembly, Supramolecular Chemistry, Quantum-Size-Related Properties, and Applications toward Biology, Catalysis, and Nanotechnology
2003 Standout
Enhanced basal and disorderly growth hormone secretion distinguish acromegalic from normal pulsatile growth hormone release.
1994
Differential orderliness of the GH release process in castrate male and female rats
1998
Inhibition of the activity of dipeptidyl-peptidase IV as a treatment for type 2 diabetes.
1998
Regulation of hypothalamic neuropeptide-Y neurons by growth hormone in the rat.
1996
The plasminogen system and cell surfaces: evidence for plasminogen and urokinase receptors on the same cell type.
1986
Spermatogenesis following male germ-cell transplantation.
1994 Standout
Effects of hypothyroidism and hyperthyroidism on insulin-like growth factors (IGFs) and growth hormone- and IGF-binding proteins.
1993
Functional Arteries Grown in Vitro
1999 StandoutScience
Role of insulin-like growth factors in embryonic and postnatal growth
1993 Standout
Plasma Insulin-Like Growth Factor-I and Prostate Cancer Risk: A Prospective Study
1998 StandoutScience
The role of galanin and its receptor in the feedback regulation of growth hormone secretion.
1996
Brown Adipose Tissue: Function and Physiological Significance
2004 Standout
Intrahypothalamic Growth Hormone Feedback: From Dwarfism to Acromegaly in the Rat
1997
ProTox-II: a webserver for the prediction of toxicity of chemicals
2018 Standout
Tissue Engineering--Current Challenges and Expanding Opportunities
2002 StandoutScience
Age-related changes in osteogenic stem cells in mice
1996
Role of selected endogenous peptides in growth hormone-releasing hexapeptide activity: analysis of growth hormone-releasing hormone, thyroid hormone-releasing hormone, and gonadotropin-releasing hormone.
1992
Wound Healing--Aiming for Perfect Skin Regeneration
1997 StandoutScience
Growth Hormone (GH)-Releasing Peptide-6 Requires Endogenous Hypothalamic GH-Releasing Hormone for Maximal GH Stimulation
1998
Integrin Signaling
1999 StandoutScience
Effects of a prolonged growth hormone (GH)-releasing peptide infusion on pulsatile GH secretion in normal men.
1993
Growth Hormone Inhibits Its Own Secretion by Acting on the Hypothalamus through Its Receptors on Neuropeptide Y Neurons in the Arcuate Nucleus and Somatostatin Neurons in the Periventricular Nucleus
1998
Gold Nanoparticles in Chemical and Biological Sensing
2012 Standout
Interaction of single-chain urokinase-type plasminogen activator with human endothelial cells.
1990 StandoutNobel
High-resolution dose–response screening using droplet-based microfluidics
2011
Sex-related differences in GH secretion in rat using reverse hemolytic plaque assay
1986
Antioxidant-induced changes of the AP-1 transcription complex are paralleled by a selective suppression of human papillomavirus transcription
1997 StandoutNobel
Characterization of an Extremely Large, Ligand-Induced Conformational Change in Plasminogen
1990 StandoutScienceNobel
Multiple Levels of Cross-Talk between Somatostatin (SRIF) and Growth Hormone (GH) -Releasing Factor in Genesis of Pulsatile GH Secretion
1994
Effects of Antagonists of Growth Hormone-Releasing Hormone (GHRH) on GH and Insulin-Like Growth Factor I Levels in Transgenic Mice Overexpressing the Human GHRH Gene, an Animal Model of Acromegaly*
1997 Nobel
Protease Inhibitors: Current Status and Future Prospects
2000
Ultradian oscillations in somatostatin and growth hormone-releasing hormone mRNAs in the brains of adult male rats.
1991
Sexual Dimorphism of Somatostatin and Growth Hormone-Releasing Factor Signaling in the Control of Pulsatile Growth Hormone Secretion in the Rat*
1991
Nocturnal growth hormone (GH) secretion is eliminated by infusion of GH-releasing hormone antagonist.
1996
Plasminogen receptors, urokinase receptors, and their modulation on human endothelial cells
1988
daf-2 , an Insulin Receptor-Like Gene That Regulates Longevity and Diapause in Caenorhabditis elegans
1997 StandoutScienceNobel
Differential effects of central and peripheral administration of growth hormone (GH) and insulin-like growth factor on hypothalamic GH-releasing hormone and somatostatin gene expression in GH-deficient dwarf rats.
1993
Growth hormone induces expression of the c-fos gene on hypothalamic neuropeptide-Y and somatostatin neurons in hypophysectomized rats.
1994
The Effect of Insulinlike Growth Factor I on Wound Healing Variables and Macrophages in Rats
1994
Role of growth hormone (GH)-releasing hormone and somatostatin in the mediation of clonidine-induced GH release in sheep.
1994
Ultradian oscillation in somatostatin binding in the arcuate nucleus of adult male rats.
1993
The Cytogenesis and Pathogenesis of Pituitary Adenomas*
1998
Females secrete growth hormone with more process irregularity than males in both humans and rats
1996
Both oral and transdermal estrogen increase growth hormone release in postmenopausal women--a clinical research center study.
1996
Sulfamic Acid and Its N- and O-Substituted Derivatives
2013
Peptidomimetic Regulation of Growth Hormone Secretion
1997
Emerging approaches in predictive toxicology
2014
Ghrelin is a growth-hormone-releasing acylated peptide from stomach
1999 StandoutNature
Effects of systemic GHRH on sleep in intact and hypophysectomized rats
1996
Central Administration of a Growth Hormone (GH) Receptor mRNA Antisense Increases GH Pulsatility and Decreases Hypothalamic Somatostatin Expression in Rats
1996
Regulation of insulin-like growth factor I gene expression by growth hormone.
1986
Accumulation of the Oxidative Base Lesion 8-Hydroxyguanine in DNA of Tumor-Prone Mice Defective in Both the Myh and Ogg1 DNA Glycosylases
2004 StandoutNobel
Sulfur(VI) Fluoride Exchange (SuFEx)-Enabled High-Throughput Medicinal Chemistry
2020 StandoutNobel
Emerging Droplet Microfluidics
2017 Standout
Effect of pyridostigmine and pirenzepine on GH responses to GHRH in hyperthyroid patients
1991
Irreversible Inhibitors of Serine, Cysteine, and Threonine Proteases
2002 Standout
A New Portal to SuFEx Click Chemistry: A Stable Fluorosulfuryl Imidazolium Salt Emerging as an “F−SO2+” Donor of Unprecedented Reactivity, Selectivity, and Scope
2017 StandoutNobel
NAD(+)-dependent repair of damaged DNA by human cell extracts.
1993 StandoutNobel
Regulation of Wound Healing by Growth Factors and Cytokines
2003 Standout
Genetic Engineering of Livestock
1989 Science
Enantioselective Total Synthesis of Nigelladine A via Late-Stage C–H Oxidation Enabled by an Engineered P450 Enzyme
2017 StandoutNobel
Works of Thomas R. Downs being referenced
Measurement of growth hormone-releasing hormone and somatostatin in hypothalamic-portal plasma of unanesthetized sheep. Spontaneous secretion and response to insulin-induced hypoglycemia.
1990
Comet assay in reconstructed 3D human epidermal skin models--investigation of intra- and inter-laboratory reproducibility with coded chemicals
2013
Feedback Regulation of Growth Hormone (GH)-Releasing Hormone Gene Expression by GH in Rat Hypothalamus
1988
Medical Management of Acromegaly Due to Ectopic Production of Growth Hormone-Releasing Hormone by a Carcinoid Tumor*
1988
Obesity-Associated Decrease in Growth Hormone-Releasing Hormone Gene Expression: A Mechanism for Reduced Growth Hormone mRNA Levels in Genetically Obese Zucker Rats
1993
Growth hormone and insulin-like growth factor-I measurements in high growth (hg) mice
1991
Effects of Thyroid Hormone Deficiency and Replacement on Rat Hypothalamic Growth Hormone (GH)-Releasing Hormone Gene Expressionin VivoAre Mediated by GH
1990
Tissue Distribution and Molecular Heterogeneity of Human Growth Hormone-Releasing Factor in the Transgenic Mouse
1990
Tissue-Specific Transcription Initiation and Effects of Growth Hormone (GH) Deficiency on the Regulation of Mouse and Rat GHReleasing Hormone Gene in Hypothalamus and Placenta
1991
Inhibitory Effect of Hypothalamic Medial Preoptic Area Somatostatin on Growth Hormone-Releasing Factor in the Rat
1988
Comparison of the Sensitivity of Growth Hormone Secretion to Somatostatinin Vivoandin Vitroin Acromegaly*
1988
Dipeptidylpeptidase IV and trypsin-like enzymatic degradation of human growth hormone-releasing hormone in plasma.
1989
Differential Effects of Somatostatin (SRIH) and a SRIH Analog, SMS 201-995, on the Secretion of Growth Hormone and Thyroid-Stimulating Hormone in Man*
1988
1,2,3,4-Tetrahydroisoquinolinyl sulfamic acids as phosphatase PTP1B inhibitors
2006
Evidence for a Defect in Growth Hormone-Releasing Factor Signal Transduction in the Dwarf (dw/dw) Rat Pituitary*
1991
Cloning and Characterization of Mouse Growth Hormone-Releasing Hormone (GRH) Complementary DNA: Increased GRH Messenger RNA Levels in the Growth Hormone-Deficient lit/lit Mouse
1989
Validation of the 3D Skin Comet assay using full thickness skin models: Transferability and reproducibility
2018
Dual Inhibition of Angiotensin-Converting Enzyme and Neutral Endopeptidase in Rats with Hypertension
1995
Effects of Intravenous, Subcutaneous, and Intranasal Administration of Growth Hormone (GH)-Releasing Hormone-40 on Serum GH Concentrations in Normal Men*
1985
Impaired growth hormone-releasing hormone signal transduction in the dwarf (dw) rat is independent of a generalized defect in the stimulatory G-protein, Gs alpha.
1993
Receptor-Associated Resistance to Growth Hormone-Releasing Factor in Dwarf "Little" Mice
1986 Science
Decreased hypothalamic growth hormone-releasing hormone content and pituitary responsiveness in hypothyroidism.
1986
[27] Measurement of growth hormone-releasing factor
1986
Development of neuroepithelial tumors of the adrenal medulla in transgenic mice expressing a mouse hypothalamic growth hormone-releasing hormone promoter-simian virus-40 T-antigen fusion gene.
1994
Morphologic effects of hGRH gene expression on the pituitary, liver, and pancreas of MT-hGRH transgenic mice. An in situ hybridization analysis.
1992
Effect of Hypophysectomy on Hypothalamic Growth Hormone-Releasing Factor Content and Release in the Rat*
1987
Fluorometric quantification of DNA in cells and tissue
1983
Regulation of growth hormone-releasing hormone gene expression and biosynthesis.
1990
Congenital gigantism due to growth hormone-releasing hormone excess and pituitary hyperplasia with adenomatous transformation.
1993
An in vitro model for studies of intercellular communication in cultured rat anterior pituitary cells
1984
Rapid enzymatic degradation of growth hormone-releasing hormone by plasma in vitro and in vivo to a biologically inactive product cleaved at the NH2 terminus.
1986