Citation Impact
Citing Papers
Directed evolution of the tryptophan synthase β-subunit for stand-alone function recapitulates allosteric activation
2015 StandoutNobel
SuFEx-enabled, agnostic discovery of covalent inhibitors of human neutrophil elastase
2019 StandoutNobel
Accurate computational design of multipass transmembrane proteins
2018 StandoutScienceNobel
Apg13p and Vac8p Are Part of a Complex of Phosphoproteins That Are Required for Cytoplasm to Vacuole Targeting
2000 StandoutNobel
Oligosaccharide specificity of galectins: a search by frontal affinity chromatography
2002
Reaching for high-hanging fruit in drug discovery at protein–protein interfaces
2007 StandoutNature
The M2 splice isoform of pyruvate kinase is important for cancer metabolism and tumour growth
2008 StandoutNature
Targeting HIF-1 for cancer therapy
2003 StandoutNobel
HIF-1 mediates metabolic responses to intratumoral hypoxia and oncogenic mutations
2013 StandoutNobel
Functional polarization of tumour-associated macrophages by tumour-derived lactic acid
2014 StandoutNature
Ald6p Is a Preferred Target for Autophagy in Yeast, Saccharomyces cerevisiae
2004 StandoutNobel
Gliomagenesis: genetic alterations and mouse models
2001
Assessment of protein models with three-dimensional profiles
1992 StandoutNature
Rational Engineering of Enzyme Allosteric Regulation through Sequence Evolution Analysis
2012
Genome-wide RNAi analysis of Caenorhabditis elegans fat regulatory genes
2003 StandoutNatureNobel
Functional Analysis of Conserved Structural Elements in Yeast Syntaxin Vam3p
2001 StandoutNobel
Acetylation Targets the M2 Isoform of Pyruvate Kinase for Degradation through Chaperone-Mediated Autophagy and Promotes Tumor Growth
2011
Nucleoside triphosphate-binding proteins: different scaffolds to achieve phosphoryl transfer
1999
Quantitative reactivity profiling predicts functional cysteines in proteomes
2010 StandoutNatureNobel
Identification of human brain tumour initiating cells
2004 StandoutNature
Pyruvate kinase M2 is a phosphotyrosine-binding protein
2008 Nature
Sulfur(VI) Fluoride Exchange (SuFEx): Another Good Reaction for Click Chemistry
2014 StandoutNobel
Pyruvate Kinase M2 Is a PHD3-Stimulated Coactivator for Hypoxia-Inducible Factor 1
2011 StandoutNobel
The Vesicle Transport Protein Vps33p Is an ATP-binding Protein That Localizes to the Cytosol in an Energy-dependent Manner
1998
Evolution of Aldolase Antibodies in Vitro : Correlation of Catalytic Activity and Reaction-based Selection
2003
Developmental regulation of energy metabolism in Caenorhabditis elegans
1989
Chaperone-mediated Autophagy Targets Hypoxia-inducible Factor-1α (HIF-1α) for Lysosomal Degradation
2013 StandoutNobel
Cysteine 288: An essential hyperreactive thiol of cytosolic phosphoenolpyruvate carboxykinase (GTP)
1989
Quantitative exploration of the molecular origin of the activation of GTPase
2013 StandoutNobel
Caclium uptake and associated adenosine triphosphatase activity in fragmented sarcoplasmic reticulum. Requirement for potassium ions.
1977
Energetics of Ligand Binding to Proteins
1975
How Is the Active Site of Enolase Organized To Catalyze Two Different Reaction Steps?
2000
Protein hydration changes during catalysis: a new mechanism of enzymic rate-enhancement and ion activation/inhibition of catalysis.
1975
Investigating Cell Surface Galectin-Mediated Cross-Linking on Glycoengineered Cells
2012 StandoutNobel
Solubilization of Enzymes and Nucleic Acids in Hydrocarbon Micellar Solution
1986
Aerobic Glycolysis: Meeting the Metabolic Requirements of Cell Proliferation
2011 Standout
Evidence for export of a muscle lectin from cytosol to extracellular matrix and for a novel secretory mechanism.
1990
On the Mechanism of Hydrolysis of Phosphate Monoesters Dianions in Solutions and Proteins
2006 StandoutNobel
The equivalence of phosphate oxygens for exchange and the hydrolysis characteristics revealed by the distribution of [18O]Pi species formed by myosin and actomyosin ATPase.
1980 StandoutNobel
The Role of Metals in Enzyme‐Catalyzed Substitutions at each of the Phosphorus Atoms of ATP
1979
Modulation of stoichiometry of the sarcoplasmic reticulum calcium pump may enhance thermodynamic efficiency.
1985 StandoutNobel
The structure of Yeast Enolase at 2.25-Å Resolution
1989
The Energy Landscapes and Motions of Proteins
1991 StandoutScience
Surfactants in nonpolar solvents
2006
Thermally Induced Structural Change of D2O-Solubilized AOT Reversed Micelles and Base-Catalyzed H−D Exchange Reaction between Solubilized D2O Deuterium and AOT−CH Proton
1996 StandoutNobel
Analysis of N-linked oligosaccharide chains of glycoproteins on nitrocellulose sheets using lectin-peroxidase reagents
1985
A Synthetic Route for Crystals of Woven Structures, Uniform Nanocrystals, and Thin Films of Imine Covalent Organic Frameworks
2017 StandoutNobel
Highly Stable Keto-Enamine Salicylideneanilines
2003
DAF-16 Target Genes That Control C. elegans Life-Span and Metabolism
2003 StandoutScienceNobel
Activities of lectins and their immobilized derivatives in detergent solutions. Implications on the use of lectin affinity chromatography for the purification of membrane glycoproteins
1977
(p-Amidinophenyl)methanesulfonyl fluoride, an irreversible inhibitor of serine proteases
1980
Mammalian beta-adrenergic receptors. Distinct glycoprotein populations containing high mannose or complex type carbohydrate chains.
1984 StandoutNobel
Exploitation of reversed micelles as membrane mimetic reagents
1984
Evaluation of synthetic linear motor-molecule actuation energetics
2006 StandoutNobel
Activation volumes in enzymic catalysis: their sources and modification by low-molecular-weight solutes.
1975
Nuclear Translocation of the Tumor Marker Pyruvate Kinase M2 Induces Programmed Cell Death
2007
Binding Energy, Specificity, and Enzymic Catalysis: The Circe Effect
1975
Intracellular Functions of N-Linked Glycans
2001 StandoutScience
Overcoming Resistance to β-Lactam Antibiotics
2013
Structural Basis for Tumor Pyruvate Kinase M2 Allosteric Regulation and Catalysis,
2005
Computationally designed peptide macrocycle inhibitors of New Delhi metallo-β-lactamase 1
2021 StandoutNobel
Entropy, Binding Energy, and Enzymic Catalysis
1977
Space-Filling Models of Kinase Clefts and Conformation Changes
1979 Science
Human galectin-1 recognition of poly-N-acetyllactosamine and chimeric polysaccharides
2003
Substrate binding closes the cleft between the domains of yeast phosphoglycerate kinase.
1979 StandoutNobel
Reversible Unfolding of Individual Titin Immunoglobulin Domains by AFM
1997 StandoutScience
Biosynthesis of N- and O-linked oligosaccharides of the low density lipoprotein receptor.
1983 StandoutNobel
A stereochemical method for detection of ATP terminal phosphate transfer in enzymatic reactions. Glutamine synthetase.
1976
Nuclear repartitioning of galectin-1 by an extracellular glycan switch regulates mammary morphogenesis
2016 StandoutNobel
The alternative splicing repressors hnRNP A1/A2 and PTB influence pyruvate kinase isoform expression and cell metabolism
2010
Electrostatic Basis for Enzyme Catalysis
2006 StandoutNobel
daf-2 , an Insulin Receptor-Like Gene That Regulates Longevity and Diapause in Caenorhabditis elegans
1997 StandoutScienceNobel
Histone demethylase JMJD2C is a coactivator for hypoxia-inducible factor 1 that is required for breast cancer progression
2012 StandoutNobel
Proton relaxation enhancement (PRE) in biochemistry: A critical survey
1979
Biogenesis of vacuolar membrane glycoproteins of yeast Saccharomyces cerevisiae.
1990 StandoutNobel
Computer simulations of enzyme catalysis: Finding out what has been optimized by evolution
1998 StandoutNobel
Transport of the vesicular stomatitis glycoprotein to trans Golgi membranes in a cell-free system.
1987 StandoutNobel
Molecular Dynamics of Ion−Chelate Complexes Attached to Dendrimers
1996 StandoutNobel
Purification and macromolecular properties of a sialic acid-specific lectin from the slug Limax flavus.
1982
De Novo Computational Design of Retro-Aldol Enzymes
2008 StandoutScienceNobel
Activation of the heat-stable polypeptide of the ATP-dependent proteolytic system.
1981 StandoutNobel
Models for the Specific Adhesion of Cells to Cells
1978 StandoutScience
The Lectins: Carbohydrate-Binding Proteins of Plants and Animals
1978
Identification of tyrosine and lysine peptides labeled by 5'-p-fluorosulfonylbenzoyl adenosine in the active site of pyruvate kinase.
1986
Living with Water Stress: Evolution of Osmolyte Systems
1982 StandoutScience
Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation
2009 StandoutScience
Carbohydrate moieties of glycoproteins a re-evaluation of their function
1982
Transition-state stabilization in the mechanism of tyrosyl-tRNA synthetase revealed by protein engineering.
1985 StandoutNobel
Urea-Linked Covalent Organic Frameworks
2018 StandoutNobel
Works of Thomas Nowak being referenced
The Proton Transfer Step Catalyzed by Yeast Pyruvate Kinase
2003
The allosteric regulation of pyruvate kinase by fructose-1,6-bisphosphate
1998
An active-site lysine in avian liver phosphoenolpyruvate carboxykinase
1991
Kinetic Linked-Function Analysis of the Multiligand Interactions on Mg2+-Activated Yeast Pyruvate Kinase
2001
NUCLEAR RELAXATION STUDIES OF THE ROLE OF THE DIVALENT CATION IN THE MECHANISM OF PYRUVATE KINASE AND ENOLASE: INNER SPHERE AND SECOND SPHERE COMPLEXES *
1973
Activation for Catalysis of Penicillin-Binding Protein 2a from Methicillin-Resistant Staphylococcus aureus by Bacterial Cell Wall
2005
Structure and state of water in reversed micelles. 3
1977
pH Dependence of the Reaction Catalyzed by Yeast Mg−Enolase
1998
Agglutinin from Limulus polyphemus. Purification with formalinized horse erythrocytes as the affinity adsorbent.
1975
Developmentally regulated lectin in embryonic chick muscle and a myogenic cell line
1976
Pyruvate kinase: Activation by and catalytic role of the monovalent and divalent cations
1981
The purification, characterization, and activation of phosphoenolpyruvate carboxykinase from chicken liver mitochondria.
1982
Fluoride inhibition of yeast enolase. 1. Formation of the ligand complexes
1981
Proton Donor in Yeast Pyruvate Kinase: Chemical and Kinetic Properties of the Active Site Thr 298 to Cys Mutant
2004
Agglutinin from Limulus polyphemus
1975
Role of Lysine 240 in the Mechanism of Yeast Pyruvate Kinase Catalysis
1999
The structure of the fluorophosphate-pyruvate kinase complex investigated by 31P relaxation rate studies
1978
Developmentally regulated lectin from embryonic chick pectoral muscle. Purification by affinity chromatography.
1977
Histological Characteristics and Expression of Acidic and Basic Fibroblast Growth Factor Genes in Intracerebral Xenogeneic Transplants of Human Glioma Cells
1994
Metal-Ion-Mediated Allosteric Triggering of Yeast Pyruvate Kinase. 1. A Multidimensional Kinetic Linked-Function Analysis
1997
Nuclear magnetic resonance studies of the function of potassium in the mechanism of pyruvate kinase
1972
Monomethylammonium Ion as a Magnetic Resonance Probe for Monovalent Cation Activators
1973
Structural changes at the active site of pyruvate kinase during activation and catalysis.
1978
Interaction of manganese with bovine factor X.
1977
Conformational changes required for pyruvate kinase activity as modulated by monovalent cations.
1976
Nuclearmagnetic resonance studies of selectively hindered internal motion of substrate analogs at the active site of pyruvate kinase
1972
Nuclear relaxation and kinetic studies of the role of Mn2+in the mechanism of enolase
1973
Kinetic evidence for a dual cation role for muscle pyruvate kinase
1982
31P-NMR studies of the metabolisms of the parasitic helminths Ascaris suum and Fasciola hepatica
1986