Citation Impact

Citing Papers

Selective targeting of engineered T cells using orthogonal IL-2 cytokine-receptor complexes
2018 StandoutScienceNobel
Differential use of endoplasmic reticulum membrane for phagocytosis in J774 macrophages
2005 StandoutNobel
Tumor-reactive CD4+ T cells develop cytotoxic activity and eradicate large established melanoma after transfer into lymphopenic hosts
2010 StandoutNobel
Genome-wide CRISPR screens reveal a specific ligand for the glycan-binding immune checkpoint receptor Siglec-7
2021 StandoutNobel
Multiple Injections of Electroporated Autologous T Cells Expressing a Chimeric Antigen Receptor Mediate Regression of Human Disseminated Tumor
2010
Endogenous human cytomegalovirus gB is presented efficiently by MHC class II molecules to CD4 + CTL
2005
Differential Expression and Function of L-Selectin on CD56bright and CD56dim Natural Killer Cell Subsets
1998
Engineered receptors for soluble cellular communication and disease sensing
2024 StandoutNatureNobel
The promise and challenge of therapeutic genome editing
2020 StandoutNatureNobel
Differential Cytokine and Chemokine Gene Expression by Human NK Cells Following Activation with IL-18 or IL-15 in Combination with IL-12: Implications for the Innate Immune Response
1999
Functional diversity of helper T lymphocytes
1996 StandoutNature
Interleukin-1β costimulates interferon-γ production by human natural killer cells
2001
Elements of cancer immunity and the cancer–immune set point
2017 StandoutNature
The biology of human natural killer-cell subsets
2001 Standout
CD56bright natural killer cell subsets: Characterization of distinct functional responses to interleukin‐2 and the c‐kit ligand
1997
Interaction between conventional dendritic cells and natural killer cells is integral to the activation of effective antiviral immunity
2005
The Orphan Nuclear Receptor RORγt Directs the Differentiation Program of Proinflammatory IL-17+ T Helper Cells
2006 Standout
Stem cells, cancer, and cancer stem cells
2001 StandoutNature
Activation of Atypical Protein Kinase C ζ by Caspase Processing and Degradation by the Ubiquitin-Proteasome System
2000 StandoutNobel
Analysis of Perforin Expression in Human Peripheral Blood Lymphocytes, CD 56+ Natural Killer Cell Subsets and Its Induction by Interleukin-2
1995
Interleukin-23 rather than interleukin-12 is the critical cytokine for autoimmune inflammation of the brain
2003 StandoutNature
Potential mechanisms of human natural killer cell expansion in vivo during low-dose IL-2 therapy
2000
The ubiquitin-proteasome proteolytic pathway
1994 StandoutNobel
A Novel Transcription Factor, T-bet, Directs Th1 Lineage Commitment
2000 Standout
Recognition of microorganisms and activation of the immune response
2007 StandoutNature
Compensatory Energetic Mechanisms Mediating the Assembly of Signaling Complexes Between Interleukin-2 and its α, β, and γc Receptors
2004
A human natural killer cell subset provides an innate source of IL-22 for mucosal immunity
2008 StandoutNature
HLA-E binds to natural killer cell receptors CD94/NKG2A, B and C
1998 StandoutNature
Selective modulation of human natural killer cells in vivo after prolonged infusion of low dose recombinant interleukin 2.
1993
Regulated portals of entry into the cell
2003 StandoutNature
Natural killer cells in viral infection: more than just killers
2006
Eater, a Transmembrane Protein Mediating Phagocytosis of Bacterial Pathogens in Drosophila
2005 StandoutNobel
Ontogeny and Expansion of Human Natural Killer Cells: Clinical Implications
2001
Functional Delineation and Differentiation Dynamics of Human CD4+ T Cells Expressing the FoxP3 Transcription Factor
2009 StandoutNobel
Sources of diversity in T cell epitope discovery
2011
Immune Checkpoint Targeting in Cancer Therapy: Toward Combination Strategies with Curative Potential
2015 StandoutNobel
Toll-like receptors in the induction of the innate immune response
2000 StandoutNature
Conserved cytoplasmic tyrosine residues of the gamma subunit are required for a phagocytic signal mediated by Fc gamma RIIIA.
1993
Jak-STAT Pathways and Transcriptional Activation in Response to IFNs and Other Extracellular Signaling Proteins
1994 StandoutScience
T cells and viral persistence: lessons from diverse infections
2005
Fc receptors: Rubor redux
1994
High prevalence of Streptococcus pyogenes Cas9-reactive T cells within the adult human population
2018
Mice Defective in Two Apoptosis Pathways in the Myeloid Lineage Develop Acute Myeloblastic Leukemia
1998
Human Natural Killer Cells: Origin, Clonality, Specificity, and Receptors
1993
Arousal and inhibition of human NK cells
1997
Restoring function in exhausted CD8 T cells during chronic viral infection
2005 StandoutNatureNobel
Function of human FcγRIIA and FcγRIIIB
1995
Sequence requirements for induction of cytolysis by the T cell antigenFc receptor ζ chain
1992
New aspects of natural-killer-cell surveillance and therapy of cancer
2002
Innate production of TH2 cytokines by adipose tissue-associated c-Kit+Sca-1+ lymphoid cells
2009 StandoutNature
Golgi Localization of Carbohydrate Sulfotransferases Is a Determinant of L-selectin Ligand Biosynthesis
2003 StandoutNobel
NK phenotypic markers and IL2 response in NK cells from elderly people
1999
Cancer exome analysis reveals a T-cell-dependent mechanism of cancer immunoediting
2012 StandoutNatureNobel
Identification of human brain tumour initiating cells
2004 StandoutNature
Requirement for Stat4 in interleukin-12-mediated responses of natural killer and T cells
1996 StandoutNatureNobel
Confronting Complexity: Real-World Immunodominance in Antiviral CD8+ T Cell Responses
2006
Natural killer cell stimulatory factor (NKSF) or interleukin-12 is a key regulator of immune response and inflammation
1992
Increased expression of the interleukin 2 (IL-2) receptor beta chain (p70) on CD56+ natural killer cells after in vivo IL-2 therapy: p70 expression does not alone predict the level of intermediate affinity IL-2 binding.
1990
NK CELL RECOGNITION
2004 Standout
IL-2 regulates FOXP3 expression in human CD4+CD25+ regulatory T cells through a STAT-dependent mechanism and induces the expansion of these cells in vivo
2006
Participation of the CD94 Receptor Complex in Costimulation of Human Natural Killer Cells
1998
Induced expression of PD-1, a novel member of the immunoglobulin gene superfamily, upon programmed cell death.
1992 StandoutNobel
Role of interleukin-15 in the development of human CD56+ natural killer cells from CD34+ hematopoietic progenitor cells
1996
Tyrosine phosphorylation and association of Syk with FcγRII in monocytic THP-1 cells
1995
Adoptive cell transfer as personalized immunotherapy for human cancer
2015 StandoutScience
Proteolytic activation of protein kinase C delta by an ICE-like protease in apoptotic cells.
1995
Interleukin-12–Activated Natural Killer Cells Recognize B7 Costimulatory Molecules on Tumor Cells and Autologous Dendritic Cells
1998
Interleukin 12 (IL-12) induces tyrosine phosphorylation of JAK2 and TYK2: differential use of Janus family tyrosine kinases by IL-2 and IL-12.
1995
Flt3 permits survival during infection by rendering dendritic cells competent to activate NK cells
2010 StandoutNobel
Sense-and-Respond Payload Delivery Using a Novel Antigen-Inducible Promoter Improves Suboptimal CAR-T Activation
2022
Control of Viremia in Simian Immunodeficiency Virus Infection by CD8 + Lymphocytes
1999 StandoutScience
Human ubiquitin-activating enzyme, E1. Indication of potential nuclear and cytoplasmic subpopulations using epitope-tagged cDNA constructs
1994 StandoutNobel
Human Dendritic Cells Activate Resting Natural Killer (NK) Cells and Are Recognized via the NKp30 Receptor by Activated NK Cells
2002 StandoutNobel
Human natural killer cells: a unique innate immunoregulatory role for the CD56bright subset
2001
Expression of a functional c-kit receptor on a subset of natural killer cells.
1993
Modification of P-selectin glycoprotein ligand-1 with a natural killer cell-restricted sulfated lactosamine creates an alternate ligand for L-selectin
2000
T cell receptor complexes containing Fc epsilon RI gamma homodimers in lieu of CD3 zeta and CD3 eta components: a novel isoform expressed on large granular lymphocytes.
1992
The functional characterization of interleukin-10 receptor expression on human natural killer cells
1995
CD1d-Restricted and TCR-Mediated Activation of V α 14 NKT Cells by Glycosylceramides
1997 StandoutScience
MECHANISMS OF PHAGOCYTOSIS IN MACROPHAGES
1999 Standout
Stimulation-dependent I kappa B alpha phosphorylation marks the NF-kappa B inhibitor for degradation via the ubiquitin-proteasome pathway.
1995 StandoutNobel
Cell surface control of the multiubiquitination and deubiquitination of high-affinity immunoglobulin E receptors.
1993
Expansion of Functional NK Cells in Multiple Tissue Compartments of Mice Treated with Flt3-Ligand: Implications for Anti-Cancer and Anti-Viral Therapy
1998
Functional expression of CD43 on human natural killer cells
1999
Detection of T cell responses to a ubiquitous cellular protein in autoimmune disease
2014 StandoutScienceNobel
Interleukin 12: A key modulator of immune function
1994
Biochemical evidence for a third chain of the interleukin-2 receptor.
1991 StandoutNobel
Cytokine Signaling Through Nonreceptor Protein Tyrosine Kinases
1995 StandoutScience
Human natural killer cells
2008
Expression of B7-1 by highly metastatic mouse T lymphomas induces optimal natural killer cell-mediated cytotoxicity.
1995
Regulation of hematopoiesis in vitro by alloreactive natural killer cell clones.
1993
Normal and leukemic hematopoiesis: Are leukemias a stem cell disorder or a reacquisition of stem cell characteristics?
2003
Effectiveness of Donor Natural Killer Cell Alloreactivity in Mismatched Hematopoietic Transplants
2002 StandoutScience
Antitumor and antimetastatic activity of interleukin 12 against murine tumors.
1993
The c-kit ligand suppresses apoptosis of human natural killer cells through the upregulation of bcl-2.
1994
Targeting of Human Dendritic Cells by Autologous NK Cells
1999
CD3+CD16+NK1.1+B220+ large granular lymphocytes arise from both alpha-beta TCR+CD4-CD8- and gamma-delta TCR+CD4-CD8- cells.
1994
CD16- CD56+ natural killer cells after bone marrow transplantation
1992
Interleukin (IL) 15 is a novel cytokine that activates human natural killer cells via components of the IL-2 receptor.
1994
THE INTERLEUKIN-12/INTERLEUKIN-12-RECEPTOR SYSTEM: Role in Normal and Pathologic Immune Responses
1998
Phylogenetic Perspectives in Innate Immunity
1999 StandoutScienceNobel
PD-1 identifies the patient-specific CD8+ tumor-reactive repertoire infiltrating human tumors
2014
Isolation of interleukin 2-induced immediate-early genes.
1993
Characterization of the interleukin 2 receptors (IL-2R) expressed on human natural killer cells activated in vivo by IL-2: association of the p64 IL-2R gamma chain with the IL-2R beta chain in functional intermediate-affinity IL-2R.
1992
THE UBIQUITIN SYSTEM
1998 StandoutNobel
Innate or Adaptive Immunity? The Example of Natural Killer Cells
2011 StandoutScience
Biology and clinical relevance of human natural killer cells
1990
Interleukin-2 enhances the response of natural killer cells to interleukin-12 through up-regulation of the interleukin-12 receptor and STAT4
2000
Analysis of Gag-specific Cytotoxic T Lymphocytes in Simian Immunodeficiency Virus–infected Rhesus Monkeys by Cell Staining with a Tetrameric Major Histocompatibility Complex Class I–Peptide Complex
1998
NATURAL KILLER CELLS IN ANTIVIRAL DEFENSE: Function and Regulation by Innate Cytokines
1999 Standout
CD1 Recognition by Mouse NK1 + T Lymphocytes
1995 StandoutScience

Works of Thomas Manley being referenced

Immune evasion proteins of human cytomegalovirus do not prevent a diverse CD8+ cytotoxic T-cell response in natural infection
2004
Functional Consequences of APO-1/Fas (CD95) Antigen Expression by Normal and Neoplastic Hematopoietic Cells
1995
Differential expression of CD8α and CD8β associated with MHC-restricted and non-MHC-restricted cytolytic effector cells
1990
Differential responses to interleukin 2 define functionally distinct subsets of human natural killer cells
1992
Activation-induced expression of CD137 permits detection, isolation, and expansion of the full repertoire of CD8+ T cells responding to antigen without requiring knowledge of epitope specificities
2007
Costimulatory signals are required for optimal proliferation of human natural killer cells
1993
Response of human natural killer (NK) cells to NK cell stimulatory factor (NKSF): cytolytic activity and proliferation of NK cells are differentially regulated by NKSF.
1992
Human natural killer cell adhesion molecules. Differential expression after activation and participation in cytolysis.
1990
Functional consequences of interleukin 2 receptor expression on resting human lymphocytes. Identification of a novel natural killer cell subset with high affinity receptors.
1990
Intracellular Retention of the MHC Class I-Related Chain B Ligand of NKG2D by the Human Cytomegalovirus UL16 Glycoprotein
2003
Fc gamma receptor type III (CD16) is included in the zeta NK receptor complex expressed by human natural killer cells.
1990
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