Citation Impact
Citing Papers
The Unconventional Secretory Machinery of Fibroblast Growth Factor 2
2011
Ligand-affinity cloning and structure of a cell surface heparan sulfate proteoglycan that binds basic fibroblast growth factor.
1990
Hallmarks of Cancer: The Next Generation
2011 Standout
Cutaneous Wound Healing
1999 Standout
Structure of the Histone Acetyltransferase Hat1
1998 StandoutNobel
The mystery of nonclassical protein secretion
2003
Inflammation and cancer
2002 StandoutNature
The Highly Cooperative Folding of Small Naturally Occurring Proteins Is Likely the Result of Natural Selection
2007 StandoutNobel
Interaction of Basic Fibroblast Growth Factor with Extracellular Matrix and Receptorsa
1991
Involvement of Reactive Oxygen Species in Cytokine and Growth Factor Induction of c-fos Expression in Chondrocytes
1995 Standout
How Tumors Become Angiogenic
1996
Patterns and Emerging Mechanisms of the Angiogenic Switch during Tumorigenesis
1996 Standout
Twenty-Five Years of the Nucleosome, Fundamental Particle of the Eukaryote Chromosome
1999 StandoutNobel
Eomesodermin, a Key Early Gene in Xenopus Mesoderm Differentiation
1996 StandoutNobel
Characterization of the Structure and Dynamics of a Near-native Equilibrium Intermediate in the Unfolding Pathway of an All β-Barrel Protein
2002
A protein-conducting channel in the endoplasmic reticulum
1991 StandoutNobel
A Xenopus mRNA related to Drosophila twist is expressed in response to induction in the mesoderm and the neural crest
1989 StandoutNobel
The generation of diversity and pattern in animal development
1992 StandoutNobel
Electrical signals control wound healing through phosphatidylinositol-3-OH kinase-γ and PTEN
2006 StandoutNatureNobel
The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis
1999 StandoutNatureNobel
Telomere states and cell fates
2000 StandoutNatureNobel
Hypoxia-mediated induction of endothelial cell interleukin-1 alpha. An autocrine mechanism promoting expression of leukocyte adhesion molecules on the vessel surface.
1992
Histone acetyltransferase activity of yeast Gcn5p is required for the activation of target genes in vivo
1998
Wnt‐1 as a short‐range signaling molecule
1994
N-Glycosylation Is Essential for Vesicular Targeting of Synaptotagmin 1
2004 StandoutNobel
Telomere Shortening and Tumor Formation by Mouse Cells Lacking Telomerase RNA
1997 StandoutNobel
The Hallmarks of Cancer
2000 Standout
Unconventional secretion: a stress on GRASP
2011
Potent synergism between vascular endothelial growth factor and basic fibroblast growth factor in the induction of angiogenesis in vitro
1992
Identification of angiogenic activity and the cloning and expression of platelet-derived endothelial cell growth factor
1989 Nature
Proteoglycans as modulators of growth factor activities
1991
Telomeres shorten during ageing of human fibroblasts
1990 StandoutNatureNobel
Structural and Functional Diversity in the FGf Receptor Multigene Family
1992
Regulators of Angiogenesis
1991
Activin signalling and response to a morphogen gradient
1994 StandoutNatureNobel
Platelet-derived growth factor mRNA detection in human atherosclerotic plaques by in situ hybridization.
1988
Tumor Induction of VEGF Promoter Activity in Stromal Cells
1998
Nopp 140 shuttles on tracks between nucleolus and cytoplasm
1992 StandoutNobel
Longevity, Stress Response, and Cancer in Aging Telomerase-Deficient Mice
1999 StandoutNobel
The biology of replicative senescence
1997
Raf-1 kinase is essential for early Xenopus development and mediates the induction of mesoderm by FGF
1993
3 Fibroblast Growth Factor and Its Involvement in Developmental Processes
1990
p53 Deficiency Rescues the Adverse Effects of Telomere Loss and Cooperates with Telomere Dysfunction to Accelerate Carcinogenesis
1999 StandoutNobel
Switching and Signaling at the Telomere
2001 StandoutNobel
Atherosclerosis — An Inflammatory Disease
1999 Standout
Mice with targeted disruptions in the paralogous genes hoxa-3 and hoxd-3 reveal synergistic interactions
1994 StandoutNatureNobel
Angiogenesis in cancer, vascular, rheumatoid and other disease
1995 Standout
Translational activation of the lck proto-oncogene
1988 StandoutNatureNobel
Short Dysfunctional Telomeres Impair Tumorigenesis in the INK4aΔ2/3 Cancer-Prone Mouse
1999 StandoutNobel
Pituitary follicular cells secrete a novel heparin-binding growth factor specific for vascular endothelial cells
1989 Standout
The angiogenic switch in carcinogenesis
2009
Treatment of skin ulcers with cultured epidermal allografts
1989
An FGF receptor signaling pathway is required for the normal cell migrations of the sex myoblasts in C. elegans hermaphrodites
1995 StandoutNobel
Insulin, Insulin-Like Growth Factor I and Platelet-Derived Growth Factor Interact Additively in the Induction of the Protooncogenec-mycand Cellular Proliferation in Cultured Bovine Aortic Smooth Muscle Cells
1989
TGFα deficiency results in hair follicle and eye abnormalities in targeted and waved-1 mice
1993 StandoutNobel
Swaying is a mutant allele of the proto-oncogene Wnt-1
1991 StandoutNobel
Disruption of the proto-oncogene int-2 in mouse embryo-derived stem cells: a general strategy for targeting mutations to non-selectable genes
1988 StandoutNatureNobel
Cooperative effect of antisense-Rb and antisense-p53 oligomers on the extension of life span in human diploid fibroblasts, TIG-1
1991
Angiogenesis and angiogenesis inhibition: An overview
1997
The pathogenesis of atherosclerosis: a perspective for the 1990s
1993 StandoutNature
Thrombin inactivates acidic fibroblast growth factor but not basic fibroblast growth factor
1988
Human Endothelial Cell Life Extension by Telomerase Expression
1999
Molecular mechanisms of action of antisense drugs
1999
Interleukin 1 receptor antagonist. A new member of the interleukin 1 family.
1991
The Tumor Necrosis Factor Ligand and Receptor Families
1996 StandoutNobel
Molecular Characterization of a Functional cDNA Encoding the Serotonin 1c Receptor
1988 StandoutScienceNobel
Saccharomyces cerevisiae STE6 gene product: a novel pathway for protein export in eukaryotic cells.
1989
Sequences of the 5′ portion of the humanc-sisgene: characterization of the transcriptional promoter and regulation of expression of the protein product by 5' untranslated mRNA sequences
1987
Fibroblast growth factors are present in the extracellular matrix produced by endothelial cells invitro: Implications for a role of heparinase-like enzymes in the neovascular response
1987
Telomere length predicts replicative capacity of human fibroblasts.
1992 StandoutNobel
Isolation and characterization of a newly identified endothelial cell mitogen produced by AtT-20 cells.
1989
Biological and biochemical properties of fibroblast growth factors. Implications for the pathogenesis of atherosclerosis.
1989
Isolation and characterization of a vascular endothelial cell mitogen produced by pituitary-derived folliculo stellate cells.
1989
A novel vascular endothelial growth factor, VEGF-C, is a ligand for the Flt4 (VEGFR-3) and KDR (VEGFR-2) receptor tyrosine kinases.
1996 Standout
Fgf-4expression during gastrulation, myogenesis, limb and tooth development in the mouse
1992
Purification and cloning of vascular endothelial growth factor secreted by pituitary folliculostellate cells
1991
A heparin-binding angiogenic protein--basic fibroblast growth factor--is stored within basement membrane.
1988
Transforming growth factor-α in the mammalian brain
1989
Genetic Models of Human Vascular Disease
1995 StandoutNobel
The fibroblast growth factor family.
1990
General involvement of hypoxia-inducible factor 1 in transcriptional response to hypoxia.
1993 StandoutNobel
The biological clock that measures the mitotic life-span of mouse embryo fibroblasts continues to function in the presence of simian virus 40 large tumor antigen.
1994
Activated human monocytes express the c-sis proto-oncogene and release a mediator showing PDGF-like activity
1986 Nature
A tyrosine-phosphorylated carboxy-terminal peptide of the fibroblast growth factor receptor (Flg) is a binding site for the SH2 domain of phospholipase C-gamma 1.
1991
The characterization of the receptor for endothelial cell growth factor by covalent ligand attachment.
1986
Unconventional Mechanisms of Protein Transport to the Cell Surface of Eukaryotic Cells
2008
Heparin-copper biaffinity chromatography of fibroblast growth factors.
1988
A Heparin-Binding Growth Factor Secreted by Macrophage-Like Cells That Is Related to EGF
1991 Science
Nucleotide Sequence of a Bovine Clone Encoding the Angiogenic Protein, Basic Fibroblast Growth Factor
1986 Science
Ectopic Expression of the Serotonin 1c Receptor and the Triggering of Malignant Transformation
1989 StandoutScienceNobel
Purification of melanoma growth stimulatory activity
1986
A human osteosarcoma cell line secretes a growth factor structurally related to a homodimer of PDGF A-chains
1986 Nature
Structural Characterization and Biological Functions of Fibroblast Growth Factor
1987
Growth factors and the pathogenesis of atherosclerosis
1986
Association of bovine brain-derived growth factor receptor with protein tyrosine kinase activity.
1986
Heparin-binding fragments of fibronectin are potent inhibitors of endothelial cell growth.
1985
Multiple RNAs expressed from the int-2 gene in mouse embryonal carcinoma cell lines encode a protein with homology to fibroblast growth factors.
1988
Rous-Whipple Award Lecture. Atherosclerosis: a defense mechanism gone awry.
1993
Requirement of Heparan Sulfate for bFGF-Mediated Fibroblast Growth and Myoblast Differentiation
1991 Science
Bovine retina contains three growth factor activities with different affinity to heparin: eye derived growth factor I, II, III
1985
Interaction of endothelial cell growth factor with heparin: characterization by receptor and antibody recognition.
1985
Induction of angiogenesis by bovine brain derived class 1 heparin-binding growth factor
1985
Purification of a factor from human placenta that stimulates capillary endothelial cell protease production, DNA synthesis, and migration.
1986
Specific inhibition of gene expression by small double-stranded RNAs in invertebrate and vertebrate systems
2001 StandoutNobel
The fms -Like Tyrosine Kinase, a Receptor for Vascular Endothelial Growth Factor
1992 StandoutScience
Angiogenesis: Models and Modulators
1995
Regulation of differentiated properties and proliferation of arterial smooth muscle cells.
1990
Vascular Endothelial Growth Factor Is a Secreted Angiogenic Mitogen
1989 StandoutScience
Three-Dimensional Structures of Acidic and Basic Fibroblast Growth Factors
1991 Science
Interferons alpha and beta down-regulate the expression of basic fibroblast growth factor in human carcinomas.
1995
Angiogenic Factors
1987 StandoutScience
Cellular Senescence revisited: a review
1987
Stimulation of aortic smooth muscle cell mitogenesis by serotonin.
1986
Recent developments in the cell biology of basic fibroblast growth factor.
1989
Cultured human endothelial cells express platelet-derived growth factor B chain: cDNA cloning and structural analysis
1985 Nature
Transforming growth factor-beta in human platelets. Identification of a major storage site, purification, and characterization.
1983 Standout
Identification of the fibroblast growth factor receptor of Swiss 3T3 cells and mouse skeletal muscle myoblasts
1986
Four classes of mRNA are expressed from the mouse int-2 gene, a member of the FGF gene family.
1988
Diverse forms of a receptor for acidic and basic fibroblast growth factors.
1990
Human platelet-derived growth factor stimulates amino acid transport and protein synthesis by human diploid fibroblasts in plasma-free media.
1982
Diversity in unconventional protein secretion
2012
Amino acid and cDNA sequences of a vascular endothelial cell mitogen that is homologous to platelet-derived growth factor.
1990
Isolation and partial characterization of an endothelial cell growth factor from the bovine kidney: homology with basic fibroblast growth factor
1985
A unique family of endothelial cell polypeptide mitogens: the antigenic and receptor cross-reactivity of bovine endothelial cell growth factor, brain-derived acidic fibroblast growth factor, and eye-derived growth factor-II.
1985
Purification and characterization of heparin-binding endothelial cell growth factors.
1986
Purification of heparin-binding growth factors
1986
PHARMACOLOGIC ENHANCEMENT OF WOUND HEALING
1995
Significance of quiescent smooth muscle migration in the injured rat carotid artery.
1985
Unconventional Secretion, Unconventional Solutions
2013 StandoutScienceNobel
The biology of platelet-derived growth factor
1986 Standout
Neurite outgrowth induced by an endothelial cell mitogen isolated from retina.
1986
Angiogenesis is stimulated by a tumor‐derived endothelial cell growth factor
1985
Mice homozygous for a targeted disruption of the proto-oncogene int-2 have developmental defects in the tail and inner ear
1993 StandoutNobel
The Platelet-Derived Growth Factor Receptor
1985
The Presence of Fibroblast Growth Factor in the Frog Egg: Its Role as a Natural Mesoderm Inducer
1988 Science
The proto-oncogene int-1 encodes a secreted protein associated with the extracellular matrix.
1990
Angiogenesis.
1992 Standout
Pure brain-derived acidic fibroblast growth factor is a potent angiogenic vascular endothelial cell mitogen with sequence homology to interleukin 1.
1985
Works of Thomas Maciag being referenced
Recombinant fibroblast growth factor-1 promotes intimal hyperplasia and angiogenesis in arteries in vivo
1993 Nature
THE HEPARIN-BINDING (FIBROBLAST) GROWTH FACTOR FAMILY OF PROTEINS
1989 Standout
S100A13 Participates in the Release of Fibroblast Growth Factor 1 in Response to Heat Shock in Vitro
2001
Copper Induces the Assembly of a Multiprotein Aggregate Implicated in the Release of Fibroblast Growth Factor 1 in Response to Stress
2001
Novel Mechanisms of Fibroblast Growth Factor 1 Function
1994
Serum-starvation induces the extracellular appearance of FGF-1
1996
Synaptotagmin-1 Is Required for Fibroblast Growth Factor-1 Release
1998
The Release of Fibroblast Growth Factor-1 from NIH 3T3 Cells in Response to Temperature Involves the Function of Cysteine Residues
1995
The Extravesicular Domain of Synaptotagmin-1 Is Released with the Latent Fibroblast Growth Factor-1 Homodimer in Response to Heat Shock
1998
Characterization of edg-2, a human homologue of theXenopus maternal transcript G10 from endothelial cells
1995
Heparin protects heparin-binding growth factor-I from proteolytic inactivation in vitro
1988
A Carboxyl-terminal Domain in Fibroblast Growth Factor (FGF)-2 Inhibits FGF-1 Release in Response to Heat Shock in Vitro
1997
The Precursor but Not the Mature Form of IL1α Blocks the Release of FGF1 in Response to Heat Shock
2001
The Cysteine Residue Responsible for the Release of Fibroblast Growth Factor-1 Resides in a Domain Independent of the Domain for Phosphatidylserine Binding
1995
S100A13 Is Involved in the Regulation of Fibroblast Growth Factor-1 and p40 Synaptotagmin-1 Release in Vitro
1998
Molecular mechanisms of angiogenesis: fibroblast growth factor signal transduction
1995
The intracellular translocation of the components of the fibroblast growth factor 1 release complex precedes their assembly prior to export
2002
Extension of the Life-Span of Human Endothelial Cells by an Interleukin-1αAntisense Oligomer
1990 Science
Autocrine and paracrine growth stimulation of cells derived from human skin
1983
Modulation of the sis Gene Transcript During Endothelial Cell Differentiation in Vitro
1985 Science
The non-classical export routes: FGF1 and IL-1α point the way
2003
Site-Directed Neovessel Formation in Vivo
1988 Science
Hormonal Requirements for Growth of Arterial Smooth Muscle Cells in vitro: An Endocrine Approach to Atherosclerosis
1981 Science
Heparin Binds Endothelial Cell Growth Factor, the Principal Endothelial Cell Mitogen in Bovine Brain
1984 Science
S100A13 mediates the copper-dependent stress-induced release of IL-1α from both human U937 and murine NIH 3T3 cells
2003
Human Endothelial Cell Growth Factor: Cloning, Nucleotide Sequence, and Chromosome Localization
1986 Science
Recovery of Mitogenic Activity of a Growth Factor Mutant with a Nuclear Translocation Sequence
1990 Science