Citation Impact
Citing Papers
An enumerative algorithm for de novo design of proteins with diverse pocket structures
2020 StandoutNobel
Loss of conformational entropy in protein folding calculated using realistic ensembles and its implications for NMR-based calculations
2014 StandoutNobel
Principles for designing proteins with cavities formed by curved β sheets
2017 StandoutScienceNobel
De novo design of transmembrane β barrels
2021 StandoutScienceNobel
Trained immunity: A program of innate immune memory in health and disease
2016 StandoutScience
The origin of β-strand bending in globular proteins
2015
Gut microbiota as the key controllers of “healthy” aging of elderly people
2021
Stability of person-specific blood-based infrared molecular fingerprints opens up prospects for health monitoring
2021 StandoutNobel
The role of short-chain fatty acids in the interplay between diet, gut microbiota, and host energy metabolism
2013 Standout
Structure of the PAPP-ABP5 complex reveals mechanism of substrate recognition
2022 StandoutNobel
Gut bacteria–host metabolic interplay during conventionalisation of the mouse germfree colon
2012
Origin of the sequence‐dependent polyproline II structure in unfolded peptides
2005
Multistate and functional protein design using RoseTTAFold sequence space diffusion
2024 StandoutNobel
The Role of Short-Chain Fatty Acids in Health and Disease
2014 Standout
Oncology Meets Immunology: The Cancer-Immunity Cycle
2013 Standout
Physical Principles of Membrane Shape Regulation by the Glycocalyx
2019 StandoutNobel
Reaching for high-hanging fruit in drug discovery at protein–protein interfaces
2007 StandoutNature
Understanding organofluorine chemistry. An introduction to the C–F bond
2007 Standout
Synthesis and structural studies of peptides containing a mannose-derived furanoid sugar amino acid
2007
Thermodynamics of a reverse turn motif. Solvent effects and side-chain packing
1997
Crosstalk between Microbiota-Derived Short-Chain Fatty Acids and Intestinal Epithelial HIF Augments Tissue Barrier Function
2015
Hallmarks of aging: An expanding universe
2023 Standout
Solution conformations and thermodynamics of structured peptides: molecular dynamics simulation with an implicit solvation model
1998
The Human Intestinal Microbiome in Health and Disease
2016 Standout
Introduction of Fluorine and Fluorine‐Containing Functional Groups
2013 Standout
Microbial Modulation of Energy Availability in the Colon Regulates Intestinal Transit
2013
Barstar is electrostatically optimized for tight binding to barnase.
2001
Structure-guided mutagenesis of a mucin-selective metalloprotease from Akkermansia muciniphila alters substrate preferences
2022 StandoutNobel
Short-Chain Fatty Acids Induce Apoptosis in Colon Cancer Cells Associated with Changes to Intracellular Redox State and Glucose Metabolism
2012
Insulin-Like Growth Factor 1 Physiology
2012
Use it or lose it to age: A review of bone and muscle communication
2018
Sodium Butyrate Induces Endoplasmic Reticulum Stress and Autophagy in Colorectal Cells: Implications for Apoptosis
2016
Gut Microbiota Regulate Motor Deficits and Neuroinflammation in a Model of Parkinson’s Disease
2016 Standout
Metabolic tinkering by the gut microbiome
2014
The Colonic Crypt Protects Stem Cells from Microbiota-Derived Metabolites
2016
Metabolic Disturbances Identified in Plasma Are Associated With Outcomes in Patients With Heart Failure
2015
Diet–microbiota interactions as moderators of human metabolism
2016 StandoutNature
Dependence of alpha-helical and beta-sheet amino acid propensities on the overall protein fold type
2012
Functional interactions between the gut microbiota and host metabolism
2012 StandoutNature
Metaboloepigenetics: Interrelationships between energy metabolism and epigenetic control of gene expression
2012
An Orientation-dependent Hydrogen Bonding Potential Improves Prediction of Specificity and Structure for Proteins and Protein–Protein Complexes
2003 StandoutNobel
Comparison of a QM/MM force field and molecular mechanics force fields in simulations of alanine and glycine “dipeptides” (Ace‐Ala‐Nme and Ace‐Gly‐Nme) in water in relation to the problem of modeling the unfolded peptide backbone in solution
2003
From Dietary Fiber to Host Physiology: Short-Chain Fatty Acids as Key Bacterial Metabolites
2016 Standout
Long term conservation of human metabolic phenotypes and link to heritability
2014
Sarcopenia
2019 Standout
Microbiome remodelling leads to inhibition of intestinal farnesoid X receptor signalling and decreased obesity
2013
De novo design of a fluorescence-activating β-barrel
2018 StandoutNatureNobel
Butyrate and Propionate Protect against Diet-Induced Obesity and Regulate Gut Hormones via Free Fatty Acid Receptor 3-Independent Mechanisms
2012
The microbiome and cancer
2013
Butyrate Activates the cAMP-Protein Kinase A-cAMP Response Element-Binding Protein Signaling Pathway in Caco-2 Cells ,
2011
Metabolomics enables precision medicine: “A White Paper, Community Perspective”
2016
The Polar Hydrophobicity of Fluorinated Compounds
2004
Commensal bacteria at the interface of host metabolism and the immune system
2013
Short Chain Fatty Acids (SCFAs)-Mediated Gut Epithelial and Immune Regulation and Its Relevance for Inflammatory Bowel Diseases
2019 Standout
Structure-based design of non-natural amino-acid inhibitors of amyloid fibril formation
2011 StandoutNatureNobel
Fusobacterium nucleatum Promotes Chemoresistance to Colorectal Cancer by Modulating Autophagy
2017 Standout
Microbial Regulation of Glucose Metabolism and Cell-Cycle Progression in Mammalian Colonocytes
2012
Quantifying Diet-Induced Metabolic Changes of the Human Gut Microbiome
2015
MetaboAnalyst 3.0—making metabolomics more meaningful
2015 Standout
Inflammation, metaflammation and immunometabolic disorders
2017 StandoutNature
Optimization of binding electrostatics: Charge complementarity in the barnase‐barstar protein complex
2001
Microbiota-Generated Metabolites Promote Metabolic Benefits via Gut-Brain Neural Circuits
2014 Standout
Identification of predictive biomarkers of disease state in transition dairy cows
2014
Close agreement between the orientation dependence of hydrogen bonds observed in protein structures and quantum mechanical calculations
2004 StandoutNobel
Metabolomics View on Gut Microbiome Modulation by Polyphenol-rich Foods
2012
The Supramolecular Chemistry of β-Sheets
2013
Calculating Structures and Free Energies of Complex Molecules: Combining Molecular Mechanics and Continuum Models
2000 Standout
Discrimination between native and intentionally misfolded conformations of proteins: ES/IS, a new method for calculating conformational free energy that uses both dynamics simulations with an explicit solvent and an implicit solvent continuum model.
1998
Helix, Sheet, and Polyproline II Frequencies and Strong Nearest Neighbor Effects in a Restricted Coil Library
2005
Regulation of immune cell function by short‐chain fatty acids
2016
Discrimination between native and intentionally misfolded conformations of proteins: ES/IS, a new method for calculating conformational free energy that uses both dynamics simulations with an explicit solvent and an implicit solvent continuum model
1998
Implicit Solvation Models: Equilibria, Structure, Spectra, and Dynamics
1999 Standout
Microbiota-activated PPAR-γ signaling inhibits dysbiotic Enterobacteriaceae expansion
2017 Science
Folding of Oligoviologens Induced by Radical–Radical Interactions
2014 StandoutNobel
The mucus and mucins of the goblet cells and enterocytes provide the first defense line of the gastrointestinal tract and interact with the immune system
2014
Fluorine in Pharmaceuticals: Looking Beyond Intuition
2007 StandoutScience
The Reciprocal Interactions between Polyphenols and Gut Microbiota and Effects on Bioaccessibility
2016 Standout
Spermidine in health and disease
2018 StandoutScience
Supramolecular Helical Systems: Helical Assemblies of Small Molecules, Foldamers, and Polymers with Chiral Amplification and Their Functions
2016 Standout
Forced unfolding of fibronectin type 3 modules: an analysis by biased molecular dynamics simulations
1999 StandoutNobel
Metabolic fate of polyphenols in the human superorganism
2010
The ecology of the microbiome: Networks, competition, and stability
2015 StandoutScience
Molecular dynamics in the endgame of protein structure prediction
2001 StandoutNobel
Evaluation of Models of Electrostatic Interactions in Proteins
2003 StandoutNobel
Quantum Mechanical Continuum Solvation Models
2005 Standout
Inhibitors of Amyloid Toxicity Based on β-sheet Packing of Aβ40 and Aβ42
2006
Local sequence of protein β‐strands influences twist and bend angles
2014
Arsenic Exposure Perturbs the Gut Microbiome and Its Metabolic Profile in Mice: An Integrated Metagenomics and Metabolomics Analysis
2014
2.1 and 1.8 Å Average Cα RMSD Structure Predictions on Two Small Proteins, HP-36 and S15
2001 StandoutNobel
Caenorhabditis elegans responses to bacteria from its natural habitats
2016 StandoutNobel
Folding of the C-terminal bacterial binding domain in statherin upon adsorption onto hydroxyapatite crystals
2006 StandoutNobel
The inconstant gut microbiota of Drosophila species revealed by 16S rRNA gene analysis
2013
MetaboAnalyst 5.0: narrowing the gap between raw spectra and functional insights
2021 Standout
Works of Thomas M. O’Connell being referenced
ACVR2B/Fc counteracts chemotherapy-induced loss of muscle and bone mass
2017
Effects of a prolonged standardized diet on normalizing the human metabolome
2009
Metabolomic Profiling Reveals Mitochondrial-Derived Lipid Biomarkers That Drive Obesity-Associated Inflammation
2012
Use of Pharmaco-Metabonomics for Early Prediction of Acetaminophen-Induced Hepatotoxicity in Humans
2010
Energetic decomposition of the α-helix-coil equilibrium of a dynamic model system
1998
Molecular Simulations of β-Sheet Twisting
1996
The Microbiome and Butyrate Regulate Energy Metabolism and Autophagy in the Mammalian Colon
2011
Anomeric Dependence of Fluorodeoxyglucose Transport in Human Erythrocytes
1994
IGF-I/IGF-Binding Protein-3 Combination Improves Insulin Resistance By GH-Dependent and Independent Mechanisms
2002
Metabolomic analysis of cancer cachexia reveals distinct lipid and glucose alterations
2008
The ?random-coil? state of proteins: Comparison of database statistics and molecular simulations
1999