Thomas M. Li

Carboxylate-bridged dinuclear manganese systems – From catalases to oxidation catalysis

Phosphorothioate analogs of 2',5'-oligoadenylate. Enzymic synthesis, properties, and biological activities of 2',5'-phosphorothioates from adenosine 5'-O-(2-thiotriphosphate) and adenosine 5'-O-(3-thiotriphosphate)

Chiral Phosphorothioates: Stereochemical Analysis of Enzymatic Substitution at Phosphorus

Phosphorothioate analogs of 2',5'-oligoadenylate. Enzymatically synthesized 2',5'-phosphorothioate dimer and trimer: unequivocal structural assignment and activation of 2',5'-oligoadenylate-dependent endoribonuclease

Structural principles for the inhibition of the 3′-5′ exonuclease activity of Escherichia coli DNA polymerase I by phosphorothioates

Are Mixed Explicit/Implicit Solvation Models Reliable for Studying Phosphate Hydrolysis? A Comparative Study of Continuum, Explicit and Mixed Solvation Models

Why nature really chose phosphate

Quantitative exploration of the molecular origin of the activation of GTPase

Geometric and Electronic Structure/Function Correlations in Non-Heme Iron Enzymes

The Active Sites in Manganese‐Containing Metalloproteins and Inorganic Model Complexes

Studies of the mechanism of action and regulation of cAMP-dependent protein kinase

Crystal structures of a tetranucleating macrocycle and its dimanganese(III) derivative, and magnetism of the latter

The Crystal Structures of Metal Complexes of Nucleic Acids and Their Constituent

The Role of Metals in Enzyme‐Catalyzed Substitutions at each of the Phosphorus Atoms of ATP

Structural and Functional Aspects of Metal Sites in Biology

Phosphate Ester Hydrolysis in Aqueous Solution:  Associative versus Dissociative Mechanisms

Stereochemical courses of nucleotidyltransferase and phosphotransferase action. Uridine diphosphate glucose pyrophosphorylase, galactose-1-phosphate uridylyltransferase, adenylate kinase, and nucleoside diphosphate kinase

The kinetics of tyrosine phosphorylation by the purified epidermal growth factor receptor kinase of A-431 cells.

Dineopentyl Phosphate Hydrolysis: Evidence for Stepwise Water Attack

Stereochemistry of enzymatic reactions of phosphates

T7-induced DNA polymerase. Requirement for thioredoxin sulfhydryl groups.

The use of synthetic peptides for defining the specificity of typrosine protein kinases

X-ray crystal and molecular structure and absolute configuration of (dihydrogen tripolyphosphato)tetraamminecobalt(III) monohydrate, Co(NH₃)₄H₂P₃O₁₀·H₂O. A model for a metal-nucleoside polyphosphate complex

Stereochemical course of nucleotidyl transfer catalyzed by bacteriophage T7 induced DNA polymerase

Stereochemical course of the reaction catalyzed by 5'-nucleotide phosphodiesterase from snake venom

Addressing Open Questions about Phosphate Hydrolysis Pathways by Careful Free Energy Mapping

Stereochemical Course of Catalysis by the Tetrahymena Ribozyme

Quantifying the Mechanism of Phosphate Monoester Hydrolysis in Aqueous Solution by Evaluating the Relevant Ab Initio QM/MM Free-Energy Surfaces

Stereochemical and kinetic studies on the action of the catalytic subunit of bovine cardiac muscle adenosine 3',5'-monophosphate dependent protein kinase using metal ion complexes of ATP.beta.S

Stereochemical course of phosphokinases. The use of adenosine [.gamma.-(S)-16O,17O,18O]triphosphate and the mechanistic consequences for the reactions catalyzed by glycerol kinase, hexokinase, pyruvate kinase, and acetate kinase

Protein Radicals in Enzyme Catalysis

The Role of Metal Ions in the Mechanisms of DNA and RNA Polymerase

Crystallographic studies and model building of ATP at the active site of hexokinase

On the Interpretation of the Observed Linear Free Energy Relationship in Phosphate Hydrolysis: A Thorough Computational Study of Phosphate Diester Hydrolysis in Solution

Predicted structures of cAMP binding domains of type I and II regulatory subunits of cAMP-dependent protein kinase

Stabilization of the tertiary structure of yeast phenylalanine tRNA by [Co(NH3)6]3+

Kinetic and magnetic resonance studies of the interaction of the Cr-ATP complex with phosphoribosylpyrophosphate synthetase from Salmonella typhimurium

Studies of the stereochemistry and of the role of metal ions in the mechanism of phosphoribosylpyrophosphate synthetase from Salmonella typhimurium.