Citation Impact
Citing Papers
Selective targeting of engineered T cells using orthogonal IL-2 cytokine-receptor complexes
2018 StandoutScienceNobel
Neutralizing antibody response during acute and chronic hepatitis C virus infection
2004 StandoutNobel
A noninflammatory mRNA vaccine for treatment of experimental autoimmune encephalomyelitis
2021 StandoutScienceNobel
The microbiota regulates type 2 immunity through RORγt + T cells
2015 StandoutScienceNobel
Satb1 regulates the effector program of encephalitogenic tissue Th17 cells in chronic inflammation
2019 StandoutNobel
CCR2 defines in vivo development and homing of IL-23-driven GM-CSF-producing Th17 cells
2015
Human immunodeficiency virus type 1 (HIV-1) infection of the central nervous system: an evaluation of cytokines in cerebrospinal fluid
1989
Impaired immune and acute-phase responses in interleukin-6-deficient mice
1994 StandoutNatureNobel
Lymphoid follicle destruction and immunosuppression after repeated CpG oligodeoxynucleotide administration
2004
Bacterial Meningitis: Pathogenesis, Pathophysiology, and Progress
1992
extradenticle, a regulator of homeotic gene activity, is a homolog of the homeobox-containing human proto-oncogene pbx1
1993 StandoutNobel
Virus persistence in acutely infected immunocompetent mice by exhaustion of antiviral cytotoxic effector T cells
1993 StandoutNature
Mice lacking the tumour necrosis factor receptor 1 are resistant to IMF-mediated toxicity but highly susceptible to infection by Listeria monocytogenes
1993 Nature
The Hox-1.3 homeo box protein is a sequence-specific DNA-binding phosphoprotein.
1989
The level of CD8 expression can determine the outcome of thymic selection
1992 StandoutNobel
Synaptic transmission: A bidirectional and self-modifiable form of cell-cell communication
1993 StandoutNobel
Normal development and function of CD8+ cells but markedly decreased helper cell activity in mice lacking CD4
1991 Nature
CD4-positive T lymphocytes are required for the generation of the primary but not the secondary CD8-positive cytolytic T lymphocyte response to herpes simplex virus in C57BL/6 mice
1991
Generation of peptide–MHC class I complexes through UV-mediated ligand exchange
2006
Protective Immunity Does Not Correlate with the Hierarchy of Virus-specific Cytotoxic T Cell Responses to Naturally Processed Peptides
1998
Prospects for a vaccine against the hepatitis C virus
2005 StandoutNatureNobel
The coming of age of de novo protein design
2016 StandoutNatureNobel
Neuropoietic cytokines in the hematopoietic fold
1991
Environmental modulation of the autonomy of cytotoxic T lymphocytes
1993
Dissection of an inflammatory process induced by CD8+ T cells
1990 StandoutNobel
Taking dendritic cells into medicine
2007 StandoutNatureNobel
Cell-mediated cytotoxicity
1993 StandoutNobel
Restoring function in exhausted CD8 T cells during chronic viral infection
2005 StandoutNatureNobel
Virus-induced autoantibody response to a transgenic viral antigen
1990 StandoutNatureNobel
Emergence of vancomycin tolerance in Streptococcus pneumoniae
1999 StandoutNatureNobel
Lysis of infected cells in vivo by antiviral cytolytic T cells demonstrated by release of cell internal viral proteins
1993
Major histocompatibility complex – dependent T cell epitopes of lymphocytic choriomeningitis virus nucleoprotein and their protective capacity against viral disease
1989
Ablation of “tolerance” and induction of diabetes by virus infection in viral antigen transgenic mice
1991
Cancer exome analysis reveals a T-cell-dependent mechanism of cancer immunoediting
2012 StandoutNatureNobel
A case for cytokines as effector molecules in the resolution of virus infection
1993
Mice deficient for the 55 kd tumor necrosis factor receptor are resistant to endotoxic shock, yet succumb to L. monocytogenes infection
1993
A Kinetic Basis For T Cell Receptor Repertoire Selection during an Immune Response
1999
Extrathymic positive selection of αβ T-cell precursors in nude mice
1992 StandoutNatureNobel
Inferences, questions and possibilities in Toll-like receptor signalling
2004 StandoutNatureNobel
Tumor necrosis factor in mediating experimental Haemophilus influenzae type B meningitis.
1989 StandoutNobel
The Tumor Necrosis Factor Ligand and Receptor Families
1996 StandoutNobel
Viral Immune Evasion Due to Persistence of Activated T Cells Without Effector Function
1998 Standout
Impaired apoptosis, extended duration of immune responses, and a lupus-like autoimmune disease in IEX-1-transgenic mice
2002 StandoutNobel
Thymocyte development is normal in CTLA-4-deficient mice
1997 StandoutNobel
Virus-induced immunosuppression: immune system-mediated destruction of virus-infected dendritic cells results in generalized immune suppression
1995
Enhanced establishment of a virus carrier state in adult CD4+ T-cell-deficient mice
1994
Generation of protein-reactive antibodies by short peptides is an event of high frequency: implications for the structural basis of immune recognition.
1983
Expression of murine interleukin 7 in a murine glioma cell line results in reduced tumorigenicity in vivo.
1992 StandoutNobel
Infection of lymphocytes by a virus that aborts cytotoxic T lymphocyte activity and establishes persistent infection.
1991
Do L3T4+ T cells act as effector cells in protection against influenza virus infection.
1987
Viral Persistence Alters CD8 T-Cell Immunodominance and Tissue Distribution and Results in Distinct Stages of Functional Impairment
2003
Viral and Bacterial Infections Interfere with Peripheral Tolerance Induction and Activate CD8+ T Cells to Cause Immunopathology
1998
Site-restricted persistent cytomegalovirus infection after selective long-term depletion of CD4+ T lymphocytes.
1989 Standout
Cd4+ T Cell Subsets during Virus Infection
2000
Vaccination with a synthetic peptide modulates lymphocytic choriomeningitis virus-mediated immunopathology
1992
Antiviral defense in mice lacking both alpha/beta and gamma interferon receptors
1995
Immune response against lymphocytic choriomeningitis virus infection in mice without CD8 expression.
1991
Clonal Deletion Versus Clonal Anergy: The Role of the Thymus in Inducing Self Tolerance
1990 StandoutScienceNobel
Induction and Exhaustion of Lymphocytic Choriomeningitis Virus–specific Cytotoxic T Lymphocytes Visualized Using Soluble Tetrameric Major Histocompatibility Complex Class I–Peptide Complexes
1998
Persistent hepatitis C virus infection in a chimpanzee is associated with emergence of a cytotoxic T lymphocyte escape variant.
1995 StandoutNobel
Contrasting Roles of IL-2 and IL-15 in the Life and Death of Lymphocytes Implications for Immunotherapy
2001
Mechanisms of mouse spleen dendritic cell function in the generation of influenza-specific, cytolytic T lymphocytes.
1992 StandoutNobel
Activation and differentiation requirements of primary T cells in vitro.
1993 StandoutNobel
Simultaneous inhibition of two regulatory T-cell subsets enhanced Interleukin-15 efficacy in a prostate tumor model
2012 StandoutNobel
Viral persistencein vivothrough selection of neutralizing antibody-escape variants
2000
Prolonged and effective blockade of tumor necrosis factor activity through adenovirus-mediated gene transfer.
1994 StandoutNobel
Avoiding horror autotoxicus: The importance of dendritic cells in peripheral T cell tolerance
2002 StandoutNobel
Interleukin 6: A Multifunctional Cytokine Regulating Immune Reactions and the Acute Phase Protein Response
1990
The Yin and Yang of T Cell Costimulation
1995 StandoutScienceNobel
Unique potential of 4-1BB agonist antibody to promote durable regression of HPV + tumors when combined with an E6/E7 peptide vaccine
2015 StandoutNobel
Activity of CD4+ T-cell clones of type 1 and type 2 in generation of influenza virus-specific cytotoxic responses in vitro
1991
Characterization of a Helical Protein Designed from First Principles
1988 Science
Host response to Sendai virus in mice lacking class II major histocompatibility complex glycoproteins
1995 StandoutNobel
Solid Phase Synthesis
1986 Science
T4+ T helper cell function in vivo: differential requirement for induction of antiviral cytotoxic T-cell and antibody responses
1988
Epigenetic conversion of conventional T cells into regulatory T cells by CD28 signal deprivation
2020 StandoutNobel
A platelet-activating factor antagonist, RP 55778, inhibits cytokine-dependent induction of human immunodeficiency virus expression in chronically infected promonocytic cells.
1993 StandoutNobel
Cytotoxic T lymphocyte antigen-4 (CTLA-4) regulates the size, reactivity, and function of a primed pool of CD4+T cells
2000 StandoutNobel
Protective Immunity Does Not Correlate with the Hierarchy of Virus-specific Cytotoxic T Cell Responses to Naturally Processed Peptides
1998
Single dose of anti–CTLA-4 enhances CD8 + T-cell memory formation, function, and maintenance
2010 StandoutNobel
Identical short peptide sequences in unrelated proteins can have different conformations: a testing ground for theories of immune recognition.
1985 StandoutNobel
Hepatitis C virus (HCV)-specific cytotoxic T lymphocytes recognize epitopes in the core and envelope proteins of HCV
1993 StandoutNobel
T cell priming versus T cell tolerance induced by synthetic peptides.
1995
Immune Response in Mice that Lack the Interferon-γ Receptor
1993 Science
Priming of CTLs by Lymphocytic Choriomeningitis Virus Depends on Dendritic Cells
2005
A maize cDNA encoding a member of the retinoblastoma protein family: involvement in endoreduplication.
1996 StandoutNobel
Impaired Effector Function of Hepatitis C Virus-Specific CD8+ T Cells in Chronic Hepatitis C Virus Infection
2002
Presentation of a Viral T Cell Epitope Expressed in the CDR3 Region of a Self Immunoglobulin Molecule
1993 StandoutScienceNobel
Function of PI3Kγ in Thymocyte Development, T Cell Activation, and Neutrophil Migration
2000 StandoutScienceNobel
Contrasting Roles of IL-2 and IL-15 in the Life and Death of Lymphocytes
2001
Adjuvant-Enhanced Antibody Responses in the Absence of Toll-Like Receptor Signaling
2006 StandoutScienceNobel
Thymic selection of H-2-incompatible bone marrow cells in SCID mice. Differences in T help for induction of B cell IgG responses versus cytotoxic T cells.
1988
Human glioblastoma cells release interleukin 6 in vivo and in vitro.
1990
Human immunodeficiency virus-specific cytotoxic responses of seropositive individuals: distinct types of effector cells mediate killing of targets expressing gag and env proteins
1989 StandoutNobel
Differential T Cell Costimulatory Requirements in CD28-Deficient Mice
1993 Science
The microbial mimic poly IC induces durable and protective CD4+T cell immunity together with a dendritic cell targeted vaccine
2008 StandoutNobel
Vaccination for Disease
1991 Science
Expression of the Serpin Serine Protease Inhibitor 6 Protects Dendritic Cells from Cytotoxic T Lymphocyte–Induced Apoptosis
2001
Unraveling Function in the TNF Ligand and Receptor Families
1994 StandoutScienceNobel
Works of Thomas Leist being referenced
Involvement of IL-15 in the Pathogenesis of Human T Lymphotropic Virus Type I-Associated Myelopathy/Tropical Spastic Paraparesis: Implications for Therapy with a Monoclonal Antibody Directed to the IL-2/15Rβ Receptor
1999
Applications of Synthetic Peptides
1985
Role of tumor necrosis factor in Listeria resistance of nude mice
1990
On the cellular source and function of interleukin 6 produced in the central nervous system in viral diseases
1989
Reduction in HTLV‐I proviral load and spontaneous lymphoproliferation in HTLV‐I–associated myelopathy/tropical spastic paraparesis patients treated with humanized anti‐tac
1998
Physicochemical and antigenic properties of synthetic fragments of human leukocyte interferon
1981 Nature
Functional analysis of T lymphocyte subsets in antiviral host defense.
1987
Tumor necrosis factor alpha in cerebrospinal fluid during bacterial, but not viral, meningitis. Evaluation in murine model infections and in patients.
1988
Impaired Generation of Anti‐Viral Cytotoxicity against Lymphocytic Choriomeningitis and Vaccinia Virus in Mice Treated with CD4‐Specific Monoclonal Antibody
1989
Susceptibility to lymphocytic choriomeningitis virus isolates correlates directly with early and high cytotoxic T cell activity, as well as with footpad swelling reaction, and all three are regulated by H-2D.
1985
Direct visualization of antigen-specific T cells: HTLV-1 Tax11–19- specific CD8+T cells are activated in peripheral blood and accumulate in cerebrospinal fluid from HAM/TSP patients
1998
Virus-triggered immune suppression in mice caused by virus-specific cytotoxic T cells.
1988
Enhanced virus replication and inhibition of lymphocytic choriomeningitis virus disease in anti-gamma interferon-treated mice
1989
Production of B cell stimulatory factor-2 and interferon gamma in the central nervous system during viral meningitis and encephalitis. Evaluation in a murine model infection and in patients.
1988
Virus-triggered acquired immunodeficiency by cytotoxic T-cell-dependent destruction of antigen-presenting cells and lymph follicle structure.
1991
Expression of GM-CSF in T Cells Is Increased in Multiple Sclerosis and Suppressed by IFN-β Therapy
2015
Involvement of IL-15 in the pathogenesis of human T lymphotropic virus type I-associated myelopathy/tropical spastic paraparesis: implications for therapy with a monoclonal antibody directed to the IL-2/15R beta receptor.
1999