Citation Impact
Citing Papers
Phosphorylation and Regulation of Akt/PKB by the Rictor-mTOR Complex
2005 StandoutScience
Stress-Dependent Regulation of FOXO Transcription Factors by the SIRT1 Deacetylase
2004 StandoutScience
Fat Metabolism Links Germline Stem Cells and Longevity in C. elegans
2008 StandoutScienceNobel
CD4+ Tregs and immune control
2004 StandoutNobel
The promise and challenge of therapeutic genome editing
2020 StandoutNatureNobel
Spatio-temporal Dynamics of Protein Kinase B/Akt Signaling Revealed by a Genetically Encoded Fluorescent Reporter
2004 StandoutNobel
Apoptosis in the nervous system
2000 StandoutNature
The Fork head transcription factor DAF-16 transduces insulin-like metabolic and longevity signals in C. elegans
1997 StandoutNatureNobel
AKT/PKB Signaling: Navigating Downstream
2007 Standout
Oncogenic kinase signalling
2001 StandoutNature
Chromatin structural elements and chromosomal translocations in leukemia
2006
Akt Promotes Cell Survival by Phosphorylating and Inhibiting a Forkhead Transcription Factor
1999 Standout
Cell Signaling by Receptor Tyrosine Kinases
2010 Standout
BCR/ABL Regulates Expression of the Cyclin-dependent Kinase Inhibitor p27Kip1 through the Phosphatidylinositol 3-Kinase/AKT Pathway
2000
Regulatory T Cells
2000 StandoutNobel
Direct control of the Forkhead transcription factor AFX by protein kinase B
1999 Nature
Phosphatidylinositol 3-Kinase Signaling Inhibits DAF-16 DNA Binding and Function via 14-3-3-dependent and 14-3-3-independent Pathways
2001 StandoutNobel
Proliferation, cell cycle and apoptosis in cancer
2001 StandoutNature
High-Resolution Profiling of Histone Methylations in the Human Genome
2007 Standout
Yeast RNA Polymerase II at 5 Å Resolution
1999 StandoutNobel
Cellular survival: a play in three Akts
1999 Standout
Forkhead transcription factor FOXO3a protects quiescent cells from oxidative stress
2002 StandoutNature
Structural Basis for DNA Recognition by FoxO1 and Its Regulation by Posttranslational Modification
2008
A soma-to-germline transformation in long-lived Caenorhabditis elegans mutants
2009 StandoutNatureNobel
Mechanisms of therapy-related carcinogenesis
2005
The Regulation and Activities of the Multifunctional Serine/Threonine Kinase Akt/PKB
1999
Food and metabolic signalling defects in a Caenorhabditis elegans serotonin-synthesis mutant
2000 StandoutNatureNobel
Phosphorylation of Serine 256 by Protein Kinase B Disrupts Transactivation by FKHR and Mediates Effects of Insulin on Insulin-like Growth Factor-binding Protein-1 Promoter Activity through a Conserved Insulin Response Sequence
1999
FoxOs Are Critical Mediators of Hematopoietic Stem Cell Resistance to Physiologic Oxidative Stress
2007
Insulin Receptor Substrate and p55 Orthologous Adaptor Proteins Function in the Caenorhabditis elegans daf-2/Insulin-like Signaling Pathway
2002 StandoutNobel
Genome-wide RNAi analysis of Caenorhabditis elegans fat regulatory genes
2003 StandoutNatureNobel
Identification of the differential distribution patterns of mRNAs and consensus binding sequences for mouse DAF-16 homologues
2000
Increased dosage of a sir-2 gene extends lifespan in Caenorhabditis elegans
2001 StandoutNature
Insulin signalling and the regulation of glucose and lipid metabolism
2001 StandoutNature
Oxidants, oxidative stress and the biology of ageing
2000 StandoutNature
Cloning and Characterization of Three Human Forkhead Genes That Comprise an FKHR-like Gene Subfamily
1998
Origin and physiological roles of inflammation
2008 StandoutNature
The C. elegans PTEN Homolog, DAF-18, Acts in the Insulin Receptor-like Metabolic Signaling Pathway
1998 StandoutNobel
Insulin Inhibits the Activation of Transcription by a C-terminal Fragment of the Forkhead Transcription Factor FKHR
2000
The role of senescent cells in ageing
2014 StandoutNature
TGF-β-induced Foxp3 inhibits TH17 cell differentiation by antagonizing RORγt function
2008 StandoutNature
Molecular evolution of FOXP2, a gene involved in speech and language
2002 StandoutNatureNobel
Genes that act downstream of DAF-16 to influence the lifespan of Caenorhabditis elegans
2003 StandoutNature
NF-κB is a target of AKT in anti-apoptotic PDGF signalling
1999 StandoutNature
Scurfin (FOXP3) Acts as a Repressor of Transcription and Regulates T Cell Activation
2001 StandoutNobel
Cell Signaling by Receptor Tyrosine Kinases
2000 Standout
Dual modulation of cell survival and cell death by β 2 -adrenergic signaling in adult mouse cardiac myocytes
2001 StandoutNobel
Architecture of an RNA Polymerase II Transcription Pre-Initiation Complex
2013 StandoutScienceNobel
Biosynthesis of the Caenorhabditis elegans dauer pheromone
2009 StandoutNobel
DAF-16 recruits the CREB-binding protein coactivator complex to the insulin-like growth factor binding protein 1 promoter in HepG2 cells
2000 StandoutNobel
Inhibition of Nuclear Import by Protein Kinase B (Akt) Regulates the Subcellular Distribution and Activity of the Forkhead Transcription Factor AFX
2001
AF6q21, a Novel Partner of the MLL Gene in t(6; 11)(q21; q23), Defines a Forkhead Transcriptional Factor Subfamily
1997
Regulation of C. elegans Life-Span by Insulinlike Signaling in the Nervous System
2000 StandoutScienceNobel
Regulation of nuclear translocation of Forkhead transcription factor AFX by protein kinase B
1999
A common muscarinic pathway for diapause recovery in the distantly related nematode species Caenorhabditis elegans and Ancylostoma caninum
2000 StandoutNobel
DAF-16 Target Genes That Control C. elegans Life-Span and Metabolism
2003 StandoutScienceNobel
The Taxonomy of Developmental Control in Caenorhabditis elegans
1998 StandoutScienceNobel
Aging, life span, and senescence
1998 StandoutNobel
Phosphatidylinositol-3-Kinase Signaling Is Required for Erythropoietin-Mediated Acute Protection Against Myocardial Ischemia/Reperfusion Injury
2004 StandoutNobel
MLL leukemia induction by genome editing of human CD34+ hematopoietic cells
2015
Factors regulating the transcriptional elongation activity of RNA polymerase II
1998
Cell Survival Promoted by the Ras-MAPK Signaling Pathway by Transcription-Dependent and -Independent Mechanisms
1999 StandoutScience
Chemotherapy triggers HIF-1–dependent glutathione synthesis and copper chelation that induces the breast cancer stem cell phenotype
2015 StandoutNobel
Structural Basis of Transcription: RNA Polymerase II at 2.8 Ångstrom Resolution
2001 StandoutScienceNobel
Normal development is an integral part of tumorigenesis in T cell-specific PTEN-deficient mice
2008 StandoutNobel
FKHR Binds the Insulin Response Element in the Insulin-Like Growth Factor Binding Protein-1 Promoter*
1999
Protein kinase B/Akt-mediated phosphorylation promotes nuclear exclusion of the winged helix transcription factor FKHR1
1999
The Many Forks in FOXO's Road
2003
Dynamic FoxO transcription factors
2007
Works of Thomas Leis being referenced
Analysis of t(9;11) chromosomal breakpoint sequences in childhood acute leukemia: Almost identical MLL breakpoints in therapy‐related AML after treatment without etoposides
2003
A DNA damage repair mechanism is involved in the origin of chromosomal translocations t(4;11) in primary leukemic cells
1999
Cloning and characterization of AFX, the gene that fuses to MLL in acute leukemias with a t(X;11)(q13;q23)
1997
Biased distribution of chromosomal breakpoints involving the MLL gene in infants versus children and adults with t(4;11) ALL
2001