Standout Papers
Citation Impact
Citing Papers
Inositol Hexakisphosphate Is Bound in the ADAR2 Core and Required for RNA Editing
2005 Science
A monomeric G protein-coupled receptor isolated in a high-density lipoprotein particle efficiently activates its G protein
2007 StandoutNobel
DNA capture by a CRISPR-Cas9–guided adenine base editor
2020 StandoutScienceNobel
Piezo1 and Piezo2 Are Essential Components of Distinct Mechanically Activated Cation Channels
2010 StandoutScienceNobel
Sparse bursts optimize information transmission in a multiplexed neural code
2018
Evolution of new nonantibody proteins via iterative somatic hypermutation
2004 StandoutNobel
Neurexin and Neuroligin Mediate Retrograde Synaptic Inhibition in C. elegans
2012 Science
Gating the Selectivity Filter in ClC Chloride Channels
2003 StandoutScienceNobel
A monomeric red fluorescent protein
2002 StandoutNobel
Q/R site editing in kainate receptor GluR5 and GluR6 pre-mRNAs requires distant intronic sequences.
1996
De novo design of modular and tunable protein biosensors
2021 StandoutNatureNobel
De novo design of allosterically switchable protein assemblies
2024 StandoutNatureNobel
Energetics of glutamate receptor ligand binding domain dimer assembly are modulated by allosteric ions
2009
Ionotropic Glutamate Receptors & CNS Disorders
2008
Creating new fluorescent probes for cell biology
2002 StandoutNobel
Base-modification mRNA editing through deamination — the good, the bad and the unregulated
1996
Glutamate receptor ion channels
2005 Standout
Structure of the TRPA1 ion channel suggests regulatory mechanisms
2015 StandoutNatureNobel
Glutamate Receptor Ion Channels: Structure, Regulation, and Function
2010 Standout
Stress-induced Apoptosis Associated with Null Mutation of ADAR1 RNA Editing Deaminase Gene
2004
Structural biology of glutamate receptor ion channel complexes
2016
X-Ray Structure of Acid-Sensing Ion Channel 1–Snake Toxin Complex Reveals Open State of a Na+-Selective Channel
2014 StandoutNobel
Channel opening and gating mechanism in AMPA-subtype glutamate receptors
2017 StandoutNatureNobel
TRPC1 and TRPC5 Form a Novel Cation Channel in Mammalian Brain
2001
Human ADAR1 Prevents Endogenous RNA from Triggering Translational Shutdown
2018 StandoutNobel
RNA Binding-independent Dimerization of Adenosine Deaminases Acting on RNA and Dominant Negative Effects of Nonfunctional Subunits on Dimer Functions
2007
[8] Substituted-cysteine accessibility method
1998
Backpropagation and the brain
2020 StandoutNobel
Mapping Neural Circuits with Activity-Dependent Nuclear Import of a Transcription Factor
2012
Presynaptic Neurexin-3 Alternative Splicing trans-Synaptically Controls Postsynaptic AMPA Receptor Trafficking
2013 StandoutNobel
Crystal structure and mechanism of a calcium-gated potassium channel
2002 StandoutNatureNobel
Nociceptive Signals Induce Trafficking of TRPA1 to the Plasma Membrane
2009 StandoutNobel
Characterization of the Ligand-binding Domains of Glutamate Receptor (GluR)-B and GluR-D Subunits Expressed in as Periplasmic Proteins
1996
Green fluorescent protein‐based halide indicators with improved chloride and iodide affinities
2001
Anion-Sensitive Fluorophore Identifies the Drosophila Swell-Activated Chloride Channel in a Genome-Wide RNA Interference Screen
2012
The role of neurexins and neuroligins in the formation, maturation, and function of vertebrate synapses
2012
Mechanisms for Activation and Antagonism of an AMPA-Sensitive Glutamate Receptor
2000
Coordination of entorhinal–hippocampal ensemble activity during associative learning
2014 StandoutNatureNobel
Glutamate receptors in the mammalian central nervous system
1998
Probing Intersubunit Interfaces in AMPA-subtype Ionotropic Glutamate Receptors
2016
TRIBE: Hijacking an RNA-Editing Enzyme to Identify Cell-Specific Targets of RNA-Binding Proteins
2016 StandoutNobel
Genetically Encodable Fluorescent Biosensors for Tracking Signaling Dynamics in Living Cells
2011
Conformational Changes That Occur during an RNA-editing Adenosine Deamination Reaction
2001
Structural Requirements for RNA Editing in Glutamate Receptor Pre-mRNAs by Recombinant Double-stranded RNA Adenosine Deaminase
1996
Four Different Subunits Are Essential for Expressing the Synaptic Glutamate Receptor at Neuromuscular Junctions ofDrosophila
2005
Membrane protein sequestering by ionic protein–lipid interactions
2011 StandoutNatureNobel
Trans-splicing in C. elegans generates the negative RNAi regulator ERI-6/7
2008 StandoutNatureNobel
Editing of α-Amino-3-hydroxy-5-methylisoxazole-4-propionic Acid Receptor GluR-B Pre-mRNA in Vitro Reveals Site-selective Adenosine to Inosine Conversion
1995
Reducing the Environmental Sensitivity of Yellow Fluorescent Protein
2001 StandoutNobel
The structure and function of G-protein-coupled receptors
2009 StandoutNatureNobel
Genomic Organization and Evolution of Alternative Exons in a Drosophila Calcium Channel Gene
1997 StandoutNobel
Neuroligin-1 Overexpression in Newborn Granule Cells In Vivo
2012
The calyx of Held
2006
Structure of a glutamate-receptor ligand-binding core in complex with kainate
1998 Nature
Transcriptome-wide sequencing reveals numerous APOBEC1 mRNA-editing targets in transcript 3′ UTRs
2011
Fluorescent proteins as a toolkit for in vivo imaging
2005
Parallel Mitral and Tufted Cell Pathways Route Distinct Odor Information to Different Targets in the Olfactory Cortex
2012
A dual-Ca2+-sensor model for neurotransmitter release in a central synapse
2007 StandoutNatureNobel
SWELL1, a Plasma Membrane Protein, Is an Essential Component of Volume-Regulated Anion Channel
2014 StandoutNobel
Higher-Order Thalamocortical Inputs Gate Synaptic Long-Term Potentiation via Disinhibition
2018
A place in the world for RNA editing
1995
The PtdIns(3,4)P2 phosphatase INPP4A is a suppressor of excitotoxic neuronal death
2010 StandoutNatureNobel
Molecular Basis for Species-Specific Sensitivity to “Hot” Chili Peppers
2002 StandoutNobel
Molecular biology of glutamate receptors in the central nervous system and their role in excitotoxicity, oxidative stress and aging
1998
A mammalian RNA editing enzyme
1996 Nature
Deep tissue two-photon microscopy
2005 Standout
DrosophilaNeuroligin 2 is Required Presynaptically and Postsynaptically for Proper Synaptic Differentiation and Synaptic Transmission
2012
The Outer Pore of the Glutamate Receptor Channel Has 2-Fold Rotational Symmetry
2004
A light-gated, potassium-selective glutamate receptor for the optical inhibition of neuronal firing
2010
Distinct Cellular Mechanisms Underlie Anti-CTLA-4 and Anti-PD-1 Checkpoint Blockade
2017 StandoutNobel
X-ray structure, symmetry and mechanism of an AMPA-subtype glutamate receptor
2009 Nature
Comprehensive Classification of Retinal Bipolar Neurons by Single-Cell Transcriptomics
2016
Class Switch Recombination and Hypermutation Require Activation-Induced Cytidine Deaminase (AID), a Potential RNA Editing Enzyme
2000 StandoutNobel
Allosteric Receptors after 30 Years
1998
Insulin disrupts β-adrenergic signalling to protein kinase A in adipocytes
2005 StandoutNatureNobel
Distinct Structural Pathways Coordinate the Activation of AMPA Receptor-Auxiliary Subunit Complexes
2016
Stargazin promotes closure of the AMPA receptor ligand-binding domain
2014
Elucidation of AMPA receptor–stargazin complexes by cryo–electron microscopy
2016 StandoutScienceNobel
Functions and Regulation of RNA Editing by ADAR Deaminases
2010
Circular permutation and receptor insertion within green fluorescent proteins
1999 StandoutNobel
RNA Editing by Adenosine Deaminases That Act on RNA
2002
Genetically encoded reporters of protein kinase A activity reveal impact of substrate tethering
2001 StandoutNobel
Stimulated emission depletion (STED) nanoscopy of a fluorescent protein-labeled organelle inside a living cell
2008 StandoutNobel
Substrate Analogues for an RNA-Editing Adenosine Deaminase: Mechanistic Investigation and Inhibitor Design
2003
ADrosophilaCalcium Channel α1 Subunit Gene Maps to a Genetic Locus Associated with Behavioral and Visual Defects
1996 StandoutNobel
The Bruchpilot cytomatrix determines the size of the readily releasable pool of synaptic vesicles
2013 StandoutNobel
Genetically Encoded Fluorescent Biosensors Illuminate the Spatiotemporal Regulation of Signaling Networks
2018
RIM-Binding Protein, a Central Part of the Active Zone, Is Essential for Neurotransmitter Release
2011 StandoutScienceNobel
Glutamate Receptor RNA Editing in Vitro by Enzymatic Conversion of Adenosine to Inosine
1995 Science
Glutamate receptor pores
2014
Molecular Structure and Physiological Function of Chloride Channels
2002
Bcl-2-mediated alterations in endoplasmic reticulum Ca 2+ analyzed with an improved genetically encoded fluorescent sensor
2004 StandoutNobel
Regulation of GPCRs by Endocytic Membrane Trafficking and Its Potential Implications
2007
Properties of the thalamic projection from the posterior medial nucleus to primary and secondary somatosensory cortices in the mouse
2011
Reversible Photocontrol of Biological Systems by the Incorporation of Molecular Photoswitches
2013 StandoutNobel
RNA editing changes the identity of a mitochondrial tRNA in marsupials.
1996 StandoutNobel
The Glutamate Receptor Ion Channels
1999 Standout
Bruchpilot Promotes Active Zone Assembly, Ca 2+ Channel Clustering, and Vesicle Release
2006 StandoutScienceNobel
X-ray structures of AMPA receptor–cone snail toxin complexes illuminate activation mechanism
2014 Science
Non-NMDA and NMDA receptor-mediated excitotoxic neuronal deaths in adult brain are morphologically distinct: Further evidence for an apoptosis-necrosis continuum
1997
Structure and gating of tetrameric glutamate receptors
2013
Editing of the GLuR-B ion channel RNA in vitro by recombinant double-stranded RNA adenosine deaminase.
1996
New directions in single-molecule imaging and analysis
2007 StandoutNobel
Overexpression of a glutamate receptor (GluR2) ligand binding domain in Escherichia coli : Application of a novel protein folding screen
1997
Neuroscience: Breaking Down Scientific Barriers to the Study of Brain and Mind
2000 StandoutScienceNobel
The glutamate receptor ion channels.
1999
Genetically encoded fluorescent reporters of protein tyrosine kinase activities in living cells
2001 StandoutNobel
The Fluorescent Toolbox for Assessing Protein Location and Function
2006 StandoutScienceNobel
Presynaptic Depression at a Calyx Synapse: The Small Contribution of Metabotropic Glutamate Receptors
1997 Nobel
Functional Significance of Cell Volume Regulatory Mechanisms
1998 Standout
Single-Channel Properties of Recombinant AMPA Receptors Depend on RNA Editing, Splice Variation, and Subunit Composition
1997
Activation Kinetics of AMPA Receptor Channels Reveal the Number of Functional Agonist Binding Sites
1998
Mechanism of interferon action: functionally distinct RNA-binding and catalytic domains in the interferon-inducible, double-stranded RNA-specific adenosine deaminase
1996
Purification and characterization of a human RNA adenosine deaminase for glutamate receptor B pre-mRNA editing
1997 StandoutNobel
Circadian neuron feedback controls the Drosophila sleep–activity profile
2016 StandoutNatureNobel
Brominated 7-hydroxycoumarin-4-ylmethyls: Photolabile protecting groups with biologically useful cross-sections for two photon photolysis
1999 StandoutNobel
Works of Thomas Kuner being referenced
Calcium-channel number critically influences synaptic strength and plasticity at the active zone
2012
Intracellular Mg2+ interacts with structural determinants of the narrow constriction contributed by the NR1‐subunit in the NMDA receptor channel
1998 Nobel
Imaging synaptic inhibition in transgenic mice expressing the chloride indicator, Clomeleon
2006
Two-Photon Imaging Reveals Somatodendritic Chloride Gradient in Retinal ON-Type Bipolar Cells Expressing the Biosensor Clomeleon
2006
Structure of the NMDA Receptor Channel M2 Segment Inferred from the Accessibility of Substituted Cysteines
1996 Nobel
A Genetically Encoded Ratiometric Indicator for Chloride
2000
Targeted in vivo expression of proteins in the calyx of Held
2004
The NMDA Receptor Channel: Molecular Design of a Coincidence Detector
1995
Adjacent asparagines in the NR2‐subunit of the NMDA receptor channel control the voltage‐dependent block by extracellular Mg2+
1998 Nobel
Imaging synaptic inhibition throughout the brain via genetically targeted Clomeleon
2008
Differential contribution of the NR1‐ and NR2A‐subunits to the selectivity filter of recombinant NMDA receptor channels.
1996 Nobel
Genetic manipulation of key determinants of ion flow in glutamate receptor channels in the mouse
2001
Maintaining Accuracy at the Expense of Speed
2004
Glutamate receptor channel signatures
2001
Dimensions of a Projection Column and Architecture of VPM and POm Axons in Rat Vibrissal Cortex
2010 Nobel
A Molecular Basis of Analgesic Tolerance to Cannabinoids
2007
Multiplexed Spike Coding and Adaptation in the Thalamus
2017
Small N‐Terminal Deletion by Splicing in Cerebellar α6 Subunit Abolishes GABAA Receptor Function
1994
A common architecture for K+ channels and ionotropic glutamate receptors?
2002
Molecular biology of glutamate receptors
1994
Donut-Like Topology of Synaptic Vesicles with a Central Cluster of Mitochondria Wrapped into Membrane Protrusions: A Novel Structure–Function Module of the Adult Calyx of Held
2006
NMDAR Channel Segments Forming the Extracellular Vestibule Inferred from the Accessibility of Substituted Cysteines
1999 Nobel
The Primordial, Blue-Cone Color System of the Mouse Retina
2005
Ethanol inhibits glutamate-induced currents in heteromeric NMDA receptor subtypes
1993
Multiple Structural Elements Determine Subunit Specificity of Mg2+Block in NMDA Receptor Channels
1996
Control of Kinetic Properties of AMPA Receptor Channels by Nuclear RNA Editing
1994 Science
The Lurcher Mutation Identifies δ2 as an AMPA/Kainate Receptor-Like Channel That Is Potentiated by Ca2+
2000
Maintaining Accuracy at the Expense of SpeedStimulus Similarity Defines Odor Discrimination Time in Mice
2004
Channel-Lining Residues of the AMPA Receptor M2 Segment: Structural Environment of the Q/R Site and Identification of the Selectivity Filter
2001 Nobel
Postsynaptic Neuroligin1 regulates presynaptic maturation
2009
DRPEER: A Motif in the Extracellular Vestibule Conferring High Ca2+Flux Rates in NMDA Receptor Channels
2002