Citation Impact
Citing Papers
IL-6 and Its Soluble Receptor Orchestrate a Temporal Switch in the Pattern of Leukocyte Recruitment Seen during Acute Inflammation
2001
Comprehensive computational design of ordered peptide macrocycles
2017 StandoutScienceNobel
Effective treatment of severe COVID-19 patients with tocilizumab
2020 Standout
Gender Disparity in Liver Cancer Due to Sex Differences in MyD88-Dependent IL-6 Production
2007 StandoutScience
Murine liver repair via transient activation of regenerative pathways in hepatocytes using lipid nanoparticle-complexed nucleoside-modified mRNA
2021 StandoutNobel
A split, conditionally active mimetic of IL-2 reduces the toxicity of systemic cytokine therapy
2022 StandoutNobel
Cytokines in inflammatory bowel disease
2014 Standout
Tumor-targeting peptides from combinatorial libraries
2016
Matrix metalloproteinases and the regulation of tissue remodelling
2007 Standout
Discoveries in structure and physiology of mechanically activated ion channels
2020 StandoutNatureNobel
Targeting Interleukin-6 Signaling in Clinic
2019
Accessories to the Crime: Functions of Cells Recruited to the Tumor Microenvironment
2012 Standout
IL-6 trans-signaling licenses mouse and human tumor microvascular gateways for trafficking of cytotoxic T cells
2011
The pro- and anti-inflammatory properties of the cytokine interleukin-6
2011 Standout
Selecting and screening recombinant antibody libraries
2005
A cytokine-mediated link between innate immunity, inflammation, and cancer
2007 Standout
Hepatitis C virus infection in human liver tissue engrafted in mice with an infectious molecular clone
2004
The biology and function of fibroblasts in cancer
2016 Standout
Beyond natural antibodies: the power of in vitro display technologies
2011
Viruses as Building Blocks for Materials and Devices
2007
Levels of sP-selectin and hs-CRP Decrease with Dietary Intervention with Selenium and Coenzyme Q10 Combined: A Secondary Analysis of a Randomized Clinical Trial
2015 StandoutNobel
A Humanized Mouse Model to Study Hepatitis C Virus Infection, Immune Response, and Liver Disease
2011 StandoutNobel
Signaling of Human Ciliary Neurotrophic Factor (CNTF) Revisited
2003
Heat Shock Protein A12B Protects Vascular Endothelial Cells Against Sepsis-Induced Acute Lung Injury in Mice
2017 Standout
The IL-6/sIL-6R complex as a novel target for therapeutic approaches
2007
Cytokines and chemokines: At the crossroads of cell signalling and inflammatory disease
2014 Standout
IL-6 as a keystone cytokine in health and disease
2015 Standout
mRNA vaccines for infectious diseases: principles, delivery and clinical translation
2021 StandoutNobel
Metagenomic biomarker discovery and explanation
2011 Standout
Tumor Necrosis Factor-α-converting Enzyme (ADAM17) Mediates the Cleavage and Shedding of Fractalkine (CX3CL1)
2001
Metalloproteinases and their natural inhibitors in inflammation and immunity
2013
Role of interleukin-6 in cancer progression and therapeutic resistance
2016
Intramuscular Delivery of Replicon RNA Encoding ZIKV-117 Human Monoclonal Antibody Protects against Zika Virus Infection
2020
Anchor extension: a structure-guided approach to design cyclic peptides targeting enzyme active sites
2021 StandoutNobel
Soluble Interleukin-6 (IL-6) Receptor/IL-6 Fusion Protein Enhances in Vitro Differentiation of Purified Rat Oligodendroglial Lineage Cells
2002
Inducible targeting of IL-13 to the adult lung causes matrix metalloproteinase– and cathepsin-dependent emphysema
2000
Targeting the IL-6/JAK/STAT3 signalling axis in cancer
2018 Standout
Remodelling the extracellular matrix in development and disease
2014 Standout
Therapeutic strategies for the clinical blockade of IL-6/gp130 signaling
2011
The IFN-λ-IFN-λR1-IL-10Rβ Complex Reveals Structural Features Underlying Type III IFN Functional Plasticity
2017 StandoutNobel
STATs in cancer inflammation and immunity: a leading role for STAT3
2009 Standout
Functional mapping and annotation of genetic associations with FUMA
2017 Standout
Intestinal epithelial cells: regulators of barrier function and immune homeostasis
2014 Standout
Mouse models of inflammatory bowel disease☆
2007
Liver regeneration: from myth to mechanism
2004
Survey of the year 2003 commercial optical biosensor literature
2004
Genetics and pathogenesis of inflammatory bowel disease
2011 StandoutNature
The STATs of cancer — new molecular targets come of age
2004 Standout
Revisiting STAT3 signalling in cancer: new and unexpected biological functions
2014 Standout
Convergent Mechanisms for Recognition of Divergent Cytokines by the Shared Signaling Receptor gp130
2003 StandoutNobel
Cancer-related inflammation
2008 StandoutNature
The Forkhead Box M1 Transcription Factor Is Essential for Embryonic Development of Pulmonary Vasculature
2005
Interleukin-6 and its receptors: A highly regulated and dynamic system
2014
Computational design of ligand-binding proteins with high affinity and selectivity
2013 StandoutNatureNobel
Muscle as an Endocrine Organ: Focus on Muscle-Derived Interleukin-6
2008 Standout
Neutrophil recruitment and function in health and inflammation
2013 Standout
Synthesis of Heterobifunctional Protein Fusions Using Copper‐Free Click Chemistry and the Aldehyde Tag
2012 StandoutNobel
Survey of the year 2001 commercial optical biosensor literature
2002
Mechanisms of implantation: strategies for successful pregnancy
2012 Standout
The Many Roles of Chemokines and Chemokine Receptors in Inflammation
2006 Standout
Interleukin-6 Signaling, Soluble Glycoprotein 130, and Inflammation in Heart Failure
2014
Evidence for heterodimeric association of leukemia inhibitory factor (LIF) receptor and gp130 in the mouse uterus for LIF signaling during blastocyst implantation
2006
Interleukin-13 Induces Tissue Fibrosis by Selectively Stimulating and Activating Transforming Growth Factor β1
2001 Standout
Self-Assembly of “S-Bilayers”, a Step Toward Expanding the Dimensionality of S-Layer Assemblies
2013 StandoutNobel
Leukemia inhibitory factor promotes nasopharyngeal carcinoma progression and radioresistance
2013
iTAP, a novel iRhom interactor, controls TNF secretion by policing the stability of iRhom/TACE
2018
Principles of interleukin (IL)-6-type cytokine signalling and its regulation
2003 Standout
Current concepts in the diagnosis and management of cytokine release syndrome
2014 Standout
The transcription factor NFATc2 controls IL-6–dependent T cell activation in experimental colitis
2008
Cytokine Storm
2020 Standout
Inflammatory Blockade Restores Adult Hippocampal Neurogenesis
2003 StandoutScience
The soluble interleukin 6 receptor: mechanisms of production and implications in disease
2001
Contributions of Amino Acid Side Chains to the Kinetics and Thermodynamics of the Bivalent Binding of Protein L to Ig κ Light Chain
2004 StandoutNobel
Precision glycocalyx editing as a strategy for cancer immunotherapy
2016 StandoutNobel
Pluripotency and nuclear reprogramming
2008 StandoutNobel
Antibody–Enzyme Fusion Proteins for Cancer Therapy
2011
Surface Plasmon Resonance Sensors for Detection of Chemical and Biological Species
2008 Standout
Structure of an Extracellular gp130 Cytokine Receptor Signaling Complex
2001 Science
Localized Oncolytic Virotherapy Overcomes Systemic Tumor Resistance to Immune Checkpoint Blockade Immunotherapy
2014 StandoutNobel
Therapeutic antibodies: their mechanisms of action and the pathological findings they induce in toxicity studies
2015
Combinatorial Peptide Libraries: Mining for Cell-Binding Peptides
2013
MyD88 signaling in nonhematopoietic cells protects mice against induced colitis by regulating specific EGF receptor ligands
2010 StandoutNobel
Inhibition of STAT3 signaling induces apoptosis and decreases survivin expression in primary effusion lymphoma
2003
Leukemia-Inhibitory Factor—Neuroimmune Modulator of Endocrine Function*
2000
Interleukin-6 biology is coordinated by membrane-bound and soluble receptors: role in inflammation and cancer
2006
Nanobodies: Natural Single-Domain Antibodies
2013 Standout
Structural Biology of Shared Cytokine Receptors
2007
Works of Thomas Jostock being referenced
Analysis of IgG heavy chain to light chain ratio with mutant Encephalomyocarditis virus internal ribosome entry site
2007
Immunoadhesins of interleukin-6 and the IL-6/soluble IL-6R fusion protein hyper-IL-6
1999
Functional knockdown of VCAM-1 at the posttranslational level with ER retained antibodies
2008
Human herpes virus 8 interleukin‐6 homologue triggers gp130 on neuronal and hematopoietic cells
2000
A New Type of Cytokine Receptor Antagonist Directly Targeting gp130
1998
Combined interleukin 6 and soluble interleukin 6 receptor accelerates murine liver regeneration
2000
Soluble gp130 is the natural inhibitor of soluble interleukin‐6 receptor transsignaling responses
2001
Rapid generation of functional human IgG antibodies derived from Fab-on-phage display libraries
2004
IL-6 Receptor Independent Stimulation of Human gp130 by Viral IL-6
2000
Blockade of IL-6 transsignaling abrogates established experimental colitis in mice by suppression of T cell resistance against apoptosis
2000
Critical role of the disintegrin metalloprotease ADAM17 for intestinal inflammation and regeneration in mice
2010
Human antibody RNase fusion protein targeting CD30+ lymphomas
2008
The importance of shedding of membrane proteins for cytokine biology.
2000
Screening of Molecular Repertoires by Microbial Surface Display
2005
The Membrane Proximal Cytokine Receptor Domain of the Human Interleukin-6 Receptor Is Sufficient for Ligand Binding but Not for gp130 Association
1998