Citation Impact
Citing Papers
Resolution of Inflammation in Murine Autoimmune Arthritis Is Disrupted by Cyclooxygenase-2 Inhibition and Restored by Prostaglandin E2-Mediated Lipoxin A4 Production
2010
Rapid Secretion of Interleukin-1β by Microvesicle Shedding
2001
Anti-inflammatory Role of Microsomal Prostaglandin E Synthase-1 in a Model of Neuroinflammation
2010
Predominance of cyclooxygenase 1 over cyclooxygenase 2 in the generation of proinflammatory prostaglandins in autoantibody‐driven K/BxN serum–transfer arthritis
2008
Natural engineering principles of electron tunnelling in biological oxidation–reduction
1999 StandoutNature
NLRP6 Inflammasome Regulates Colonic Microbial Ecology and Risk for Colitis
2011 Standout
Pro-resolving lipid mediators are leads for resolution physiology
2014 StandoutNature
Cryopyrin activates the inflammasome in response to toxins and ATP
2006 StandoutNature
Cell death by pyroptosis drives CD4 T-cell depletion in HIV-1 infection
2013 Nature
Membrane Prostaglandin E Synthase-1: A Novel Therapeutic Target
2007 Nobel
X-linked IAP is a direct inhibitor of cell-death proteases
1997 StandoutNature
Cardiovascular Risk Associated with Celecoxib in a Clinical Trial for Colorectal Adenoma Prevention
2005 Standout
COX-2 and beyond: approaches to prostaglandin inhibition in human disease
2003
Direct Binding of Activated c-Src to the β3-Adrenergic Receptor Is Required for MAP Kinase Activation
2000 StandoutNobel
Platelet Activation and Atherothrombosis
2007 Standout
mPGES-1 deletion impairs diuretic response to acute water loading
2009
PPAR-γ agonists inhibit production of monocyte inflammatory cytokines
1998 StandoutNature
Regulation of Ferroptotic Cancer Cell Death by GPX4
2014 Standout
Microsomal prostaglandin E synthase-2 is not essential for in vivo prostaglandin E2 biosynthesis
2008
The Caenorhabditis elegans cell-death protein CED-3 is a cysteine protease with substrate specificities similar to those of the human CPP32 protease.
1996 StandoutNobel
Ferroptosis: An Iron-Dependent Form of Nonapoptotic Cell Death
2012 Standout
Microsomal prostaglandin E synthase-1 is the central switch during immune-induced pyresis
2003
Altered Cytokine Production in Mice Lacking P2X7Receptors
2001
Spinal inflammatory hyperalgesia is mediated by prostaglandin E receptors of the EP2 subtype
2005
Protease activation during apoptosis: Death by a thousand cuts?
1995 Standout
Interleukin‐18 and Host Defense against Infection
2003
Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death
2015 StandoutNature
Identification and inhibition of the ICE/CED-3 protease necessary for mammalian apoptosis
1995 StandoutNature
Yama/CPP32β, a mammalian homolog of CED-3, is a CrmA-inhibitable protease that cleaves the death substrate poly(ADP-ribose) polymerase
1995 Standout
Differential activation of the inflammasome by caspase-1 adaptors ASC and Ipaf
2004 StandoutNature
FLICE, A Novel FADD-Homologous ICE/CED-3–like Protease, Is Recruited to the CD95 (Fas/APO-1) Death-Inducing Signaling Complex
1996 Standout
Reduced Pain Hypersensitivity and Inflammation in Mice Lacking Microsomal Prostaglandin E Synthase-1
2004
Non-canonical inflammasome activation targets caspase-11
2011 StandoutNature
Prostaglandin E2 synthesis and secretion: The role of PGE2 synthases
2006
Peroxisome Proliferator-activated Receptors α and γ Are Activated by Indomethacin and Other Non-steroidal Anti-inflammatory Drugs
1997
The Therapeutic Potential of Modifying Inflammasomes and NOD-Like Receptors
2013
Pyroptosis: host cell death and inflammation
2009 Standout
The Inflammasomes
2010 Standout
Mechanisms and Functions of Inflammasomes
2014 Standout
Cyclooxygenases, microsomal prostaglandin E synthase-1, and cardiovascular function
2006
Consequences of altered eicosanoid patterns for nociceptive processing in mPGES‐1‐deficient mice
2007
Extracellular mRNA Induces Dendritic Cell Activation by Stimulating Tumor Necrosis Factor-α Secretion and Signaling through a Nucleotide Receptor
2002 StandoutNobel
Mechanisms of caspase-1 activation by P2X7 receptor-mediated K+ release
2004
Prostacyclin Antagonism Reduces Pain and Inflammation in Rodent Models of Hyperalgesia and Chronic Arthritis
2006
lincRNAs act in the circuitry controlling pluripotency and differentiation
2011 StandoutNature
Hyperhomocysteinemia: An Independent Risk Factor for Vascular Disease
1991 Standout
Alterations in cellular adhesion and apoptosis in epithelial cells overexpressing prostaglandin endoperoxide synthase 2
1995 Standout
Staphylococcus aureusInfections
1998 Standout
Inflammasomes in health and disease
2012 StandoutNature
Decreased apoptosis in the brain and premature lethality in CPP32-deficient mice
1996 StandoutNature
Defects in the Ubiquitin Pathway Induce Caspase-independent Apoptosis Blocked by Bcl-2
1998 StandoutNobel
Nucleotide receptors: an emerging family of regulatory molecules in blood cells
2001
Anthrax lethal toxin-induced inflammasome formation and caspase-1 activation are late events dependent on ion fluxes and the proteasome
2007
Altered Cytokine Export and Apoptosis in Mice Deficient in Interleukin-1β Converting Enzyme
1995 Science
Dose-related inhibition of colon carcinogenesis by dietary piroxicam, a nonsteroidal antiinflammatory drug, during different stages of rat colon tumor development.
1987
Oxidative inactivation of leukotriene C 4 by stimulated human polymorphonuclear leukocytes
1982 StandoutNobel
The suppressive effect of piroxicam on autochthonous intestinal tumors in the rat
1983
Leukocyte lipid body formation and eicosanoid generation: cyclooxygenase-independent inhibition by aspirin.
1996 StandoutNobel
Lipoxygenase and Leukotriene Pathways: Biochemistry, Biology, and Roles in Disease
2011
Chemoprevention of colon carcinogenesis by concurrent administration of piroxicam, a nonsteroidal antiinflammatory drug with D,L-alpha-difluoromethylornithine, an ornithine decarboxylase inhibitor, in diet.
1990
Ca2+ Stores and Ca2+ Entry Differentially Contribute to the Release of IL-1β and IL-1α from Murine Macrophages
2003
P2X7 Receptor-Dependent Blebbing and the Activation of Rho-Effector Kinases, Caspases, and IL-1β Release
2003
Aspirin Use and Reduced Risk of Fatal Colon Cancer
1991 Standout
Prostacyclin-IP signaling and prostaglandin E2-EP2/EP4 signaling both mediate joint inflammation in mouse collagen-induced arthritis
2006
Loss of the autophagy protein Atg16L1 enhances endotoxin-induced IL-1β production
2008 StandoutNature
Peroxide mediated effects of homocysteine on arterial prostacyclin synthesis
1986
Radioimmunoassay of the leukotrienes of slow reacting substance of anaphylaxis.
1981
Interferon-Stimulated Genes: A Complex Web of Host Defenses
2014 StandoutNobel
GLUTATHIONE TRANSFERASES
2004 Standout
NF-κB-dependent induction of microRNA miR-146, an inhibitor targeted to signaling proteins of innate immune responses
2006 StandoutNobel
Antiinflammatory Action of Glucocorticoids — New Mechanisms for Old Drugs
2005 Standout
Copper induces cell death by targeting lipoylated TCA cycle proteins
2022 StandoutScience
Cancer Chemopreventive Activity of Resveratrol, a Natural Product Derived from Grapes
1997 StandoutScience
Matrix Metalloproteinase Inhibitors and Cancer—Trials and Tribulations
2002 StandoutScience
A Key Role for Redox Signaling in Rapid P2X7 Receptor-Induced IL-1β Processing in Human Monocytes
2008
Potassium-inhibited processing of IL-1 beta in human monocytes.
1995
Tissue-specific contributions of Tmem79 to atopic dermatitis and mast cell-mediated histaminergic itch
2018 StandoutNobel
Interleukin-1 beta maturation and release in response to ATP and nigericin. Evidence that potassium depletion mediated by these agents is a necessary and common feature of their activity.
1994
Protein Radicals in Enzyme Catalysis
1998 Standout
Nonclassical IL-1β Secretion Stimulated by P2X7 Receptors Is Dependent on Inflammasome Activation and Correlated with Exosome Release in Murine Macrophages
2007
Prostaglandins and Inflammation
2011 Standout
Design and Therapeutic Application of Matrix Metalloproteinase Inhibitors
1999
Effects of exogenous arachidonic, eicosapentaenoic, and docosahexaenoic acids on the generation of 5-lipoxygenase pathway products by ionophore-activated human neutrophils.
1984 StandoutNobel
Regulatory Mechanism and Physiological Role of Cytosolic Phospholipase A2
2004
Unconventional Secretion, Unconventional Solutions
2013 StandoutScienceNobel
The P2 purinergic receptors of human dendritic cells: identification and coupling to cytokine release
2000
Salicylate fails to prevent the inhibitory effect of 5,8,11,14-eicosatetraynoic acid on human platelet cyclo-oxygenase and lipoxygenase activities
1983
Hydroxamates: Relationships between Structure and Plasma Stability
2009
Proton-Coupled Electron Transfer
2012 Standout
Synopsis of Some Recent Tactical Application of Bioisosteres in Drug Design
2011 Standout
The Connectivity Map: Using Gene-Expression Signatures to Connect Small Molecules, Genes, and Disease
2006 StandoutScience
Deletion of microsomal prostaglandin E synthase-1 augments prostacyclin and retards atherogenesis
2006
Works of Thomas J. Carty being referenced
1,2-Dihydro-1-oxopyrrolo[3,2,1-kl]phenothiazine-2-carboxamides and congeners, dual cyclooxygenase/5-lipoxygenase inhibitors with anti-inflammatory activity
1990
Inhibition of 5‐lipoxygenase product formation and polymorphonuclear cell degranulation by tenidap sodium in patients with rheumatoid arthritis
1991
Discovery of 3,3-dimethyl-5-hydroxypipecolic hydroxamate-based inhibitors of aggrecanase and MMP-13
2005
New Insights into Disintegrin Metalloproteases
1999
Benzimidazolone p38 inhibitors
2004
Redirection of Eicosanoid Metabolism in mPGES-1-deficient Macrophages
2005
Tranylcypromine and 15-hydroperoxyarachidonate affect arachidonic acid release in addition to inhibition of prostacyclin synthesis in calf aortic endothelial cells.
1980
Preparation of [3H]-12-L-hydroxyeicosatetraenoic acid and its use in radioimmunoassay.
1980
The development of a radioimmunoassay for 12-L-hydroxyeicosatetraenoic acid
1980
Impaired inflammatory and pain responses in mice lacking an inducible prostaglandin E synthase
2003
Preparation of [3H]-12-L-hydroxyeicosatetraenoic acid and its use in radioimmunoassay
1980
IL-1 beta maturation: evidence that mature cytokine formation can be induced specifically by nigericin
1992
Piroxicam, a potent inhibitor of prostaglandin production in cell culture. Structure-activity study
1980
The Mechanism of Action of Ethanolamine Ammonia-Lyase, a B12-dependent Enzyme
1974